How to search

HOME> Products> Natural and Chemical compound> Bioactive Compounds

Institute of Microbial Chemistry (BIKAKEN) Bioactive Compounds

Date：November 26 2020Web Page No：90012

Institute of Microbial Chemistry

Bioactive compounds listed here are produced by the Institute of Microbial Chemistry (BIKAKEN). These products are useful for drug screenings and various pharmacological activity assays (inhibition assays).

What is BIKAKEN

The Institute of Microbial Chemistry (BIKAKEN) was established in 1962 using funds raised from royalties from the new antibiotic kanamycin, which was discovered by the late Dr. Hamao Umezawa. The institute has since given rise to numerous beneficial antibiotics, including kasugamycin, which is highly effective against rice blast, and bleomycin, which was the world’s first target-specific anticancer agent. It has continued to conduct research and development on antibacterial agents, anticancer agents, antiviral agents, etc. by microbial drug discovery, as well as organic synthesis research and process research on pharmaceutical products. To date, there have been 14 medicines created by the Institute of Microbial Chemistry, including the antibacterial agents dibekacin and arbekacin, the anticancer agents bleomycin, peplomycin, aclarubicin, the veterinary agents aivlosin, tildipirosin, and the pesticide kasugamycin. BIKAKEN’s unique bioactive compounds from microorganisms are widely used in the world as research reagents and contribute to scientific development.


Go back to index

Product Lineup

Enzyme Inhibitor or Enzyme Resistant Substance

FunctionDescriptionProduct Code
Inhibition of DNA helicase Heliquinomycin 10665
Inhibition of GMP synthase Oxanosine 00762
Inhibition of NADH (ubiquinone oxidoreductase) Piericidin A1 14688
Inhibition of NDPK (nucleoside diphosphate kinase) Cyclamidomycin 01541
Inhibition of α-glucosidase 6-O-Methylreticulol 14693
Inhibition of β-galactosidase Pyridindolol 00372
Inhibition of alkaline phosphatase Forphenicin 09636
Inhibition of glyoxalase-I (GloI) COTC 14675
Inhibition of glutathione S-transferase Benastatin A 00379
Benastatin B 14653
Benastatin C 00380
Bequinostatin A 14681
Bequinostatin C 14654
Inhibition of dipeptidyl aminopeptidase Dioctatin A (Hydrochloride) 14700
Inhibition of dipeptidyl peptidase Ⅲ Fluostatin A (Sodium Salt) 15403
Fluostatin B 14683
Inhibition of protein phosphatase 2A Cytostatin (sodium salt) 10664
Rubratoxin A 10663
Inhibition of thymidylate synthase Vanoxonin 10744
Inhibition of tyrosine kinase Erbstatin 14697
Inhibition of dopamine β-hydroxylase Dopastin 00381
Inhibition of heparanase Heparastatin (Hydrochloride) <SF-4> 11829
Inhibition of phospholipase A2 Plipastatin A1 15170
Suppression GRP78 up-regulation Piericidin A1 14688
Resistance to trehalase Lentztrehalose A 14678
Lentztrehalose B 14679
Lentztrehalose C 14680

Biological Activity

FunctionDescriptionProduct Code
Anti-tumor Altemicidin 12151
Bactobolin A (Hydrochloride) 08465
Bisucaberin 14659
COMC 14701
COTC 14675
6-epi-COTC 14698
Forphenicinol 09637
Inostamycin A (Sodium Salt) 14652
Iturin A-2 15171
Lentztrehalose A 14678
Migrastatin 10708
Oxanosine 00762
Metastasis control Migrastatin 10708
Antimicrobe (gram-positive & negative) Althiomycin 14660
Bactobolin A (Hydrochloride) 08465
Cyclamidomycin 01541
Negamycin (Sodium Salt) 14662
Anti-gram positive bacteria Bottromycin A2 00592
Anti-MRSA, Anti-VRE Bottromycin A2 00592
Anti-resporatory infectious bacteria Forphenicinol 09637
Acid-fast bacillus growth suppression Minosaminomycin 02872
Anti-fungal Benanomicin A 02966
Benanomicin B 02968
Iturin A-2 15171
Plipastatin A1 15170
Inhibition of protein synthesis in bacteria Althiomycin 14660
Minosaminomycin 02872
Negamycin 14662
Pneumocystis pneumonia suppression Benanomicin A 02966
Anti-HIV-Ⅰ Benanomicin A 02966
Benanomicin B 02968
Immunoregulation Forphenicinol 09637
Inhibition of aflatoxin production Dioctatin A (Hydrochloride) 14700
Lectin-like function Benanomicin A 02966
Induced systemic resistance Iturin A-2 15171
Plipastatin A1 15170

Inhibition of DNA Helicase

[Date : October 09 2025 00:07]

Detail Product Name Product Code Supplier Size Price
Heliquinomycin, DNA Helicase Inhibitor
DatasheetThis may not be the latest data sheet. 		10665 IMCInstitute of Microbial Chemistry 1 mg $500

Description M.W.: 698.5811 Purity : > 80％ (HPLC) Molecular Formula : C33H30O17 Solubility : Soluble in EtOAc, EtOH, and DMSO, Insoluble in H2O, and Hexane. Heliquinomycin is a natural product derived from actinomycetes and inhibits DNA helicase. This compound inhibits DNA helicase from HeLa cell (Ki＝6.8 mM). In addition, it inhibits growth of human tumor cell lines such as HeLa S3, KB, LS180, K562, and HL60 (IC50＝0.96～2.8 μg/ml). In cell culture, this compound also inhibits both DNA and RNA synthesis but do not inhibit protein synthesis. It was reported that HeLa S3 growth was arrested at G2/M phase by Heliquinomycin treatment.
Storage -20°C CAS 178182-49-5
Link

Heliquinomycin
Natural compound Product List

[Date : October 09 2025 00:07]

Heliquinomycin, DNA Helicase Inhibitor

DatasheetThis may not be the latest data sheet.


  • Product Code: 10665
  • Supplier: IMC
  • Size: 1mg
  • Price: $500

Description M.W.: 698.5811 Purity : > 80％ (HPLC) Molecular Formula : C33H30O17 Solubility : Soluble in EtOAc, EtOH, and DMSO, Insoluble in H2O, and Hexane. Heliquinomycin is a natural product derived from actinomycetes and inhibits DNA helicase. This compound inhibits DNA helicase from HeLa cell (Ki＝6.8 mM). In addition, it inhibits growth of human tumor cell lines such as HeLa S3, KB, LS180, K562, and HL60 (IC50＝0.96～2.8 μg/ml). In cell culture, this compound also inhibits both DNA and RNA synthesis but do not inhibit protein synthesis. It was reported that HeLa S3 growth was arrested at G2/M phase by Heliquinomycin treatment.
Storage -20°C CAS 178182-49-5
Link

Heliquinomycin
Natural compound Product List


Back to Product Lineup


Inhibition of GMP Synthase

[Date : October 09 2025 00:07]

Detail Product Name Product Code Supplier Size Price
Oxanosine, Antitumor, GMP Synthase Inhibitor
DatasheetThis may not be the latest data sheet. 		00762 IMCInstitute of Microbial Chemistry 1 mg $500

Description M.W.: 284.23 Purity : > 98％ (HPLC) Molecular Formula : C10H12N4O6 Solubility : Soluble in H2O, Methanol, and DMSO, Insoluble in CHCl3. Inhibitory activity of leukemia L210 : IC50=1.0 μg/ml, Competitive inhibitory activity of GMP synthase : Ki=7.4x10-4 M. Oxanosine was isolated from culture broth of Streptomyces capreolus MG265-CF3 and was reported as a novel nucleoside. It was also reported that this compound has an inhibitory activity of HIV replication and leukemia L1210 cell growth.
Storage -20°C CAS 80394-72-5
Link

Oxanosine

[Date : October 09 2025 00:07]

Oxanosine, Antitumor, GMP Synthase Inhibitor

DatasheetThis may not be the latest data sheet.


  • Product Code: 00762
  • Supplier: IMC
  • Size: 1mg
  • Price: $500

Description M.W.: 284.23 Purity : > 98％ (HPLC) Molecular Formula : C10H12N4O6 Solubility : Soluble in H2O, Methanol, and DMSO, Insoluble in CHCl3. Inhibitory activity of leukemia L210 : IC50=1.0 μg/ml, Competitive inhibitory activity of GMP synthase : Ki=7.4x10-4 M. Oxanosine was isolated from culture broth of Streptomyces capreolus MG265-CF3 and was reported as a novel nucleoside. It was also reported that this compound has an inhibitory activity of HIV replication and leukemia L1210 cell growth.
Storage -20°C CAS 80394-72-5
Link

Oxanosine


Back to Product Lineup


Inhibition of NADH (ubiquinone oxidoreductase)

[Date : October 09 2025 00:07]

Detail Product Name Product Code Supplier Size Price
Piericidin A1, NADH:Ubiquinone Oxidoreductase Inhibitor
DatasheetThis may not be the latest data sheet. 		14688 IMCInstitute of Microbial Chemistry 3x1 mg $500

Description M.W.: 415.574 Purity : >90％ (HPLC) Molecular Formula : C25H37NO4 Supplied as: EtOH solution (1 mg/mL) Solubility : Soluble in MeOH, EtOH, hexane, and DMF, Hardly soluble in H2O. Piericidin A1 is a bioactive compound which is known as a specific inhibitor of the respiratory chain in the electron transport system. This compound inhibits functions of the respiratory chain by targeting to the ubiquinone binding site on the respiratory complex I (also known as NADH:ubiquinone oxidoreductase).
Storage -20°C,Dark Storage CAS 2738-64-9
Link

Piericidin A1

[Date : October 09 2025 00:07]

Piericidin A1, NADH:Ubiquinone Oxidoreductase Inhibitor

DatasheetThis may not be the latest data sheet.


  • Product Code: 14688
  • Supplier: IMC
  • Size: 3x1mg
  • Price: $500

Description M.W.: 415.574 Purity : >90％ (HPLC) Molecular Formula : C25H37NO4 Supplied as: EtOH solution (1 mg/mL) Solubility : Soluble in MeOH, EtOH, hexane, and DMF, Hardly soluble in H2O. Piericidin A1 is a bioactive compound which is known as a specific inhibitor of the respiratory chain in the electron transport system. This compound inhibits functions of the respiratory chain by targeting to the ubiquinone binding site on the respiratory complex I (also known as NADH:ubiquinone oxidoreductase).
Storage -20°C,Dark Storage CAS 2738-64-9
Link

Piericidin A1


Back to Product Lineup


Inhibition of NDPK (Nucleoside Diphosphate Kinase)

[Date : October 09 2025 00:07]

Detail Product Name Product Code Supplier Size Price
Cyclamidomycin, Nucleoside Diphosphate Kinase (NDPK) Inhibitor, Antibacterial (Gram-Positive & Negative)
DatasheetThis may not be the latest data sheet. 		01541 IMCInstitute of Microbial Chemistry 1 mg $500

Description M.W.: 138.17 Purity : > 98％ (HPLC) Molecular Formula : C7H10N2O Solubility : Soluble in H2O, Insoluble : Hexane, and MeOH. Cyclamidomycin (synonyms: Desdanine) is isolated from cultures of Streptomyces sp.MA130-A1. It is reported that this compound inhibited nucleoside diphosphate kinase of Escherichia coli and growth of gram-positive and gram-negative bacteria. In addition, cyclamidomycin inhibited plaque formation of male-specific coliphages and suppress the multiplication of both RNA phage Qβ and filamentous DNA phage f1.
Storage -20°C CAS 35663-85-5
Link

Cyclamidomycin

[Date : October 09 2025 00:07]

Cyclamidomycin, Nucleoside Diphosphate Kinase (NDPK) Inhibitor, Antibacterial (Gram-Positive & Negative)

DatasheetThis may not be the latest data sheet.


  • Product Code: 01541
  • Supplier: IMC
  • Size: 1mg
  • Price: $500

Description M.W.: 138.17 Purity : > 98％ (HPLC) Molecular Formula : C7H10N2O Solubility : Soluble in H2O, Insoluble : Hexane, and MeOH. Cyclamidomycin (synonyms: Desdanine) is isolated from cultures of Streptomyces sp.MA130-A1. It is reported that this compound inhibited nucleoside diphosphate kinase of Escherichia coli and growth of gram-positive and gram-negative bacteria. In addition, cyclamidomycin inhibited plaque formation of male-specific coliphages and suppress the multiplication of both RNA phage Qβ and filamentous DNA phage f1.
Storage -20°C CAS 35663-85-5
Link

Cyclamidomycin


Back to Product Lineup


Inhibition of α-glucosidase

[Date : October 09 2025 00:07]

Detail Product Name Product Code Supplier Size Price
6-O-Methylreticulol, cyclic AMP Phosphodiesterase Inhibitor, α-Glucosidase Inhibitor
DatasheetThis may not be the latest data sheet. 		14693 IMCInstitute of Microbial Chemistry 1 mg $500

Description M.W.: 236.223 Purity : > 98％ (HPLC) Molecular Formula : C12H12O5 Solubility : Soluble in Methanol, DMSO, and DMF, Insoluble in H2O, This compound is a natural derivative of Reticulol which has methyl-ether group at carbon 6. The compound was reported to exhibit weak inhibitory activity of cAMP phosphodiesterase as well as Reticulol, and also inhibits α-glucosidase activity.
Storage -20°C CAS 24350-93-4
Link

6-O-Methylreticulol [CAS: 24350-93-4]

[Date : October 09 2025 00:07]

6-O-Methylreticulol, cyclic AMP Phosphodiesterase Inhibitor, α-Glucosidase Inhibitor

DatasheetThis may not be the latest data sheet.


  • Product Code: 14693
  • Supplier: IMC
  • Size: 1mg
  • Price: $500

Description M.W.: 236.223 Purity : > 98％ (HPLC) Molecular Formula : C12H12O5 Solubility : Soluble in Methanol, DMSO, and DMF, Insoluble in H2O, This compound is a natural derivative of Reticulol which has methyl-ether group at carbon 6. The compound was reported to exhibit weak inhibitory activity of cAMP phosphodiesterase as well as Reticulol, and also inhibits α-glucosidase activity.
Storage -20°C CAS 24350-93-4
Link

6-O-Methylreticulol [CAS: 24350-93-4]


Back to Product Lineup


Inhibition of β-galactosidase

[Date : October 09 2025 00:07]

Detail Product Name Product Code Supplier Size Price
Pyridindolol, β-Galactosidase Inhibitor
DatasheetThis may not be the latest data sheet. 		00372 IMCInstitute of Microbial Chemistry 1 mg $500

Description M.W.: 258.27 Purity : >90% (HPLC) Molecular Formula : C14H14N2O3 Solubility : Soluble in MeOH, EtOH, n-butanol, DMSO, DMF, and 0.5N HCl Pyridindolol has inhibitory activity against neutral bovine liver β-galactosidase which has optimal activity at pH 5.0 in tris acetate buffer. This bioactive compound shows no antibacterial and antifungal activity at 100 μg/ml and has low toxicity (LD50 >500 mg/kg, intraperitoneal injection) to mice.
Storage -20°C CAS 55812-46-9
Link

Pyridindolol

[Date : October 09 2025 00:07]

Pyridindolol, β-Galactosidase Inhibitor

DatasheetThis may not be the latest data sheet.


  • Product Code: 00372
  • Supplier: IMC
  • Size: 1mg
  • Price: $500

Description M.W.: 258.27 Purity : >90% (HPLC) Molecular Formula : C14H14N2O3 Solubility : Soluble in MeOH, EtOH, n-butanol, DMSO, DMF, and 0.5N HCl Pyridindolol has inhibitory activity against neutral bovine liver β-galactosidase which has optimal activity at pH 5.0 in tris acetate buffer. This bioactive compound shows no antibacterial and antifungal activity at 100 μg/ml and has low toxicity (LD50 >500 mg/kg, intraperitoneal injection) to mice.
Storage -20°C CAS 55812-46-9
Link

Pyridindolol


Back to Product Lineup


Inhibition of Alkaline Phosphatase

[Date : October 09 2025 00:07]

Detail Product Name Product Code Supplier Size Price
Forphenicine, Alkaline Phosphatase Inhibitor
DatasheetThis may not be the latest data sheet. 		09636 IMCInstitute of Microbial Chemistry 1 mg $500

Description M.W.: 195.174 Purity : > 90％ (HPLC) Molecular Formula : C9H9NO4 Solubility : Soluble in dilute acetic acid, dilute aqueous HCl, and H2O Insoluble in MeOH, Benzene, Pyridine and DMSO, Forphenicine is an inhibitor of alkaline phosphatase which was isolated from bacterial culture of Streptomyces fulvoviridis var. acarbodicus MC974-A5. It was reported that this compound enhances delayed-type hypersensitivity to sheep red blood cells (SRBCs) and antibody production in mice.
Storage -20°C CAS 57784-96-0
Link

Forphenicine

[Date : October 09 2025 00:07]

Forphenicine, Alkaline Phosphatase Inhibitor

DatasheetThis may not be the latest data sheet.


  • Product Code: 09636
  • Supplier: IMC
  • Size: 1mg
  • Price: $500

Description M.W.: 195.174 Purity : > 90％ (HPLC) Molecular Formula : C9H9NO4 Solubility : Soluble in dilute acetic acid, dilute aqueous HCl, and H2O Insoluble in MeOH, Benzene, Pyridine and DMSO, Forphenicine is an inhibitor of alkaline phosphatase which was isolated from bacterial culture of Streptomyces fulvoviridis var. acarbodicus MC974-A5. It was reported that this compound enhances delayed-type hypersensitivity to sheep red blood cells (SRBCs) and antibody production in mice.
Storage -20°C CAS 57784-96-0
Link

Forphenicine


Back to Product Lineup


Inhibition of Glyoxalase-I (GloI)

[Date : October 09 2025 00:07]

Detail Product Name Product Code Supplier Size Price
COTC, Glyoxalase-I Inhibitor
DatasheetThis may not be the latest data sheet. 		14675 IMCInstitute of Microbial Chemistry 1 mg $500

Description M.W.: 242.227 Purity : >90% (HPLC) Molecular Formula : C11H14O6 Solubility : Soluble in MeOH, DMSO, and H2O, Insoluble in hexane, blocks enzymatic activity of alkaline phosphodiesterase derived from murine lymphoblastoma L5178Y cells (IC50: 60ug/ml), glyoxylase I in rat liver crude (IC50: 1.8 mM), and in yeast (IC50: 1.4 mM)
Storage -20°C CAS 57449-30-6
Link

COTC

[Date : October 09 2025 00:07]

COTC, Glyoxalase-I Inhibitor

DatasheetThis may not be the latest data sheet.


  • Product Code: 14675
  • Supplier: IMC
  • Size: 1mg
  • Price: $500

Description M.W.: 242.227 Purity : >90% (HPLC) Molecular Formula : C11H14O6 Solubility : Soluble in MeOH, DMSO, and H2O, Insoluble in hexane, blocks enzymatic activity of alkaline phosphodiesterase derived from murine lymphoblastoma L5178Y cells (IC50: 60ug/ml), glyoxylase I in rat liver crude (IC50: 1.8 mM), and in yeast (IC50: 1.4 mM)
Storage -20°C CAS 57449-30-6
Link

COTC


Back to Product Lineup


Inhibition of Glutathione S-transferase

[Date : October 09 2025 00:07]

Detail Product Name Product Code Supplier Size Price
Benastatin A, Glutathione S-Transferase (GST) Inhibitor
DatasheetThis may not be the latest data sheet. 		00379 IMCInstitute of Microbial Chemistry 1 mg $500

Description M.W.: 500.547 Purity : > 95％ (HPLC) Molecular Formula : C30H28O7 Solubility : Soluble in DMSO, Poorly soluble in MeOH, and CHCl3, Insoluble in H2O. Benastatin A is isolated from the culture broth of Streptomyces sp. MI384-DF12 as an inhibitor of glutathione S-transferase (GST). It was reported that the natural compound has antibacterial activity against gram-positive bacteria including methicillin-resistant Staphylococcus aureus (MRSA).
Storage -20°C CAS 138968-85-1
Link

Benastatin A

Benastatin B, Glutathione S-Transferase (GST) Inhibitor
DatasheetThis may not be the latest data sheet. 		14653 IMCInstitute of Microbial Chemistry 1 mg $500

Description M.W.: 502.563 Purity : > 95％ (HPLC) Molecular Formula : C30H30O7 Solubility : Soluble in DMSO, Poorly soluble in MeOH, Acetone, EtOAc, Insoluble in H2O. Benastatin B exhibited competitive inhibitory activity with 3,4-dichloronitrobenzene (Ki:3.7×10^-6 M), and noncompetitive with glutathione (Ki:4.2×10^-6 M). In addition, this compound also has anti-bacterial activity against Gram-positive bacteria including methicillin-resistant Staphylococcus aureus (MRSA).
Storage -20°C CAS 138968-86-2
Link

Benastatin B

Benastatin C, Glutathione S-Transferase (GST) Inhibitor
DatasheetThis may not be the latest data sheet. 		00380 IMCInstitute of Microbial Chemistry 1 mg $500

Description M.W.: 456.538 Purity : >95% (HPLC) Molecular Formula : C29H28O5 Solubility : Soluble in DMSO, MeOH, acetone, and EtOAc Insoluble in H2O Benactatin C is reported an inhibitor of glutathione S-transferase (GST). The compound showed inhibitory activity to human pi class GST (GSTπ), and esterase from hog pancreas lipase, and in vitro stimulatory activities on the murine lymphocyte blastogenesis.
Storage -20°C CAS 150151-88-5
Link

Benastatin C

Bequinostatin A, Glutathione S-Transferase (GST) π Class Inhibitor
DatasheetThis may not be the latest data sheet. 		14681 IMCInstitute of Microbial Chemistry 1 mg $500

Description M.W.: 504.491 Purity : >75% (HPLC) Molecular Formula : C28H24O9 Solubility : Soluble in DMSO, MeOH, and pyridine Insoluble in H2O (Note: Bequinostatin A seems to change to bequinostatin C slowly in the solution condition. The stock solution should be stored at 4 degree or lower, and be used within a couple of days.) Bequinostatin A is isolated from the culture broth of Streptomyces sp., and it has a significant inhibitory activity against human pi class glutathione S-transferase (GSTπ) expressed in carcinogenesis. This product contains approximately 20% bequinostatin C.
Storage -20°C CAS 151013-37-5
Link

Bequinostatin A

Bequinostatin C, Glutathione S-Transferase (GST) π Class Inhibitor
DatasheetThis may not be the latest data sheet. 		14654 IMCInstitute of Microbial Chemistry 1 mg $500

Description M.W.: 486.476 Purity : > 90％ (HPLC) Molecular Formula : C28H22O8 Solubility : Soluble in Methanol, and DMSO (<0.2 mg/ml), Insoluble in H2O. Inhibitory activity of humanπ class glutathione S-transferase(GSTπ) expressed in carcinogenesis (IC50: 40 μg/mL). Bequinostatin C was isolated from the culture broth of Streptomyces sp. MI384-DF12, and it has inhibitory activity against humanπ class glutathione S-transferase. It was also reported that this compound exhibited no toxicity after intraperitoneal injection in mice at a dose of 100 mg/kg.
Storage -20°C CAS 152175-74-1
Link

Bequinostatin C

[Date : October 09 2025 00:07]

Benastatin A, Glutathione S-Transferase (GST) Inhibitor

DatasheetThis may not be the latest data sheet.


  • Product Code: 00379
  • Supplier: IMC
  • Size: 1mg
  • Price: $500

Description M.W.: 500.547 Purity : > 95％ (HPLC) Molecular Formula : C30H28O7 Solubility : Soluble in DMSO, Poorly soluble in MeOH, and CHCl3, Insoluble in H2O. Benastatin A is isolated from the culture broth of Streptomyces sp. MI384-DF12 as an inhibitor of glutathione S-transferase (GST). It was reported that the natural compound has antibacterial activity against gram-positive bacteria including methicillin-resistant Staphylococcus aureus (MRSA).
Storage -20°C CAS 138968-85-1
Link

Benastatin A

Benastatin B, Glutathione S-Transferase (GST) Inhibitor

DatasheetThis may not be the latest data sheet.


  • Product Code: 14653
  • Supplier: IMC
  • Size: 1mg
  • Price: $500

Description M.W.: 502.563 Purity : > 95％ (HPLC) Molecular Formula : C30H30O7 Solubility : Soluble in DMSO, Poorly soluble in MeOH, Acetone, EtOAc, Insoluble in H2O. Benastatin B exhibited competitive inhibitory activity with 3,4-dichloronitrobenzene (Ki:3.7×10^-6 M), and noncompetitive with glutathione (Ki:4.2×10^-6 M). In addition, this compound also has anti-bacterial activity against Gram-positive bacteria including methicillin-resistant Staphylococcus aureus (MRSA).
Storage -20°C CAS 138968-86-2
Link

Benastatin B

Benastatin C, Glutathione S-Transferase (GST) Inhibitor

DatasheetThis may not be the latest data sheet.


  • Product Code: 00380
  • Supplier: IMC
  • Size: 1mg
  • Price: $500

Description M.W.: 456.538 Purity : >95% (HPLC) Molecular Formula : C29H28O5 Solubility : Soluble in DMSO, MeOH, acetone, and EtOAc Insoluble in H2O Benactatin C is reported an inhibitor of glutathione S-transferase (GST). The compound showed inhibitory activity to human pi class GST (GSTπ), and esterase from hog pancreas lipase, and in vitro stimulatory activities on the murine lymphocyte blastogenesis.
Storage -20°C CAS 150151-88-5
Link

Benastatin C

Bequinostatin A, Glutathione S-Transferase (GST) π Class Inhibitor

DatasheetThis may not be the latest data sheet.


  • Product Code: 14681
  • Supplier: IMC
  • Size: 1mg
  • Price: $500

Description M.W.: 504.491 Purity : >75% (HPLC) Molecular Formula : C28H24O9 Solubility : Soluble in DMSO, MeOH, and pyridine Insoluble in H2O (Note: Bequinostatin A seems to change to bequinostatin C slowly in the solution condition. The stock solution should be stored at 4 degree or lower, and be used within a couple of days.) Bequinostatin A is isolated from the culture broth of Streptomyces sp., and it has a significant inhibitory activity against human pi class glutathione S-transferase (GSTπ) expressed in carcinogenesis. This product contains approximately 20% bequinostatin C.
Storage -20°C CAS 151013-37-5
Link

Bequinostatin A

Bequinostatin C, Glutathione S-Transferase (GST) π Class Inhibitor

DatasheetThis may not be the latest data sheet.


  • Product Code: 14654
  • Supplier: IMC
  • Size: 1mg
  • Price: $500

Description M.W.: 486.476 Purity : > 90％ (HPLC) Molecular Formula : C28H22O8 Solubility : Soluble in Methanol, and DMSO (<0.2 mg/ml), Insoluble in H2O. Inhibitory activity of humanπ class glutathione S-transferase(GSTπ) expressed in carcinogenesis (IC50: 40 μg/mL). Bequinostatin C was isolated from the culture broth of Streptomyces sp. MI384-DF12, and it has inhibitory activity against humanπ class glutathione S-transferase. It was also reported that this compound exhibited no toxicity after intraperitoneal injection in mice at a dose of 100 mg/kg.
Storage -20°C CAS 152175-74-1
Link

Bequinostatin C


Back to Product Lineup


Inhibition of Dipeptidyl Aminopeptidase

[Date : October 09 2025 00:07]

Detail Product Name Product Code Supplier Size Price
Dioctatin A (Hydrochloride), Human Dipeptidyl Aminopeptidase II Inhibitor, Aflatoxin Production Inhibitor
DatasheetThis may not be the latest data sheet. 		14700 IMCInstitute of Microbial Chemistry 1 mg $500

Description M.W.: 434.018 (hydrochloride salt form) Purity : >95% (HPLC) Molecular Formula : C21H39N3O4･HCl Solubility : Soluble in acidic DMSO, acidic MeOH, and acidic H2O Dioctatin A is a selective inhibitor of dipeptidyl aminopeptidase II (DPP2) in pancreas of rat. It was found that this bioactive compound strongly inhibited aflatoxin production by Aspergillus parasiticus.
Storage -20°C CAS 138146-67-5 (salt free form)
Link

Dioctatin A (Hydrochloride)

[Date : October 09 2025 00:07]

Dioctatin A (Hydrochloride), Human Dipeptidyl Aminopeptidase II Inhibitor, Aflatoxin Production Inhibitor

DatasheetThis may not be the latest data sheet.


  • Product Code: 14700
  • Supplier: IMC
  • Size: 1mg
  • Price: $500

Description M.W.: 434.018 (hydrochloride salt form) Purity : >95% (HPLC) Molecular Formula : C21H39N3O4･HCl Solubility : Soluble in acidic DMSO, acidic MeOH, and acidic H2O Dioctatin A is a selective inhibitor of dipeptidyl aminopeptidase II (DPP2) in pancreas of rat. It was found that this bioactive compound strongly inhibited aflatoxin production by Aspergillus parasiticus.
Storage -20°C CAS 138146-67-5 (salt free form)
Link

Dioctatin A (Hydrochloride)


Back to Product Lineup


Inhibition of Dipeptidyl Peptidase Ⅲ

[Date : October 09 2025 00:07]

Detail Product Name Product Code Supplier Size Price
Fluostatin A (sodium salt), Dipeptidyl Peptidase Ⅲ (DPP-Ⅲ) Inhibitor
DatasheetThis may not be the latest data sheet. 		15403 IMCInstitute of Microbial Chemistry 1 mg $500

Description M.W.: 328.255 (sodium salt form) Purity : >98% (HPLC) Molecular Formula : C18H9O5Na (sodium salt form) Solubility : Soluble in DMSO, and H2O. Poorly soluble in MeOH Fluostatin A is a selective human placental dipeptidyl peptidase III (DPP-III, DPP3) inhibitor isolated from the fermentation broth of Streptomyces sp. As productivity of fluostatin A by the strain is significantly low, fluostatin A was prepared from fluostatin B by chemical dehydration and oxidation. It was reported that fluostatin A has approximately 50 times higher inhibitory activity against human DPP III than fluostatin B.
Storage -20°C CAS 160219-74-9 (salt free form)
Link

Fluostatin A, B

Fluostatin B, Dipeptidyl Peptidase III (DPP-III) Inhibitor
DatasheetThis may not be the latest data sheet. 		14683 IMCInstitute of Microbial Chemistry 1 mg $500

Description M.W.: 326.304 Purity : > 98％ (HPLC) Molecular Formula : C18H14O6 Solubility : Soluble in DMSO Partially soluble in EtOAc, and Acetone Insoluble in H2O. Fluostatin B is isolated from Streptomyces sp. TA-3391 and inhibits human placental DPP-III selectively (IC50: 24 μg/mL). It was reported that the compound exhibited no toxicity after intraperitoneal injection in mice at a dose of 100 mg/kg.
Storage -20°C CAS 158906-40-2
Link

Fluostatin A, B

[Date : October 09 2025 00:07]

Fluostatin A (sodium salt), Dipeptidyl Peptidase Ⅲ (DPP-Ⅲ) Inhibitor

DatasheetThis may not be the latest data sheet.


  • Product Code: 15403
  • Supplier: IMC
  • Size: 1mg
  • Price: $500

Description M.W.: 328.255 (sodium salt form) Purity : >98% (HPLC) Molecular Formula : C18H9O5Na (sodium salt form) Solubility : Soluble in DMSO, and H2O. Poorly soluble in MeOH Fluostatin A is a selective human placental dipeptidyl peptidase III (DPP-III, DPP3) inhibitor isolated from the fermentation broth of Streptomyces sp. As productivity of fluostatin A by the strain is significantly low, fluostatin A was prepared from fluostatin B by chemical dehydration and oxidation. It was reported that fluostatin A has approximately 50 times higher inhibitory activity against human DPP III than fluostatin B.
Storage -20°C CAS 160219-74-9 (salt free form)
Link

Fluostatin A, B

Fluostatin B, Dipeptidyl Peptidase III (DPP-III) Inhibitor

DatasheetThis may not be the latest data sheet.


  • Product Code: 14683
  • Supplier: IMC
  • Size: 1mg
  • Price: $500

Description M.W.: 326.304 Purity : > 98％ (HPLC) Molecular Formula : C18H14O6 Solubility : Soluble in DMSO Partially soluble in EtOAc, and Acetone Insoluble in H2O. Fluostatin B is isolated from Streptomyces sp. TA-3391 and inhibits human placental DPP-III selectively (IC50: 24 μg/mL). It was reported that the compound exhibited no toxicity after intraperitoneal injection in mice at a dose of 100 mg/kg.
Storage -20°C CAS 158906-40-2
Link

Fluostatin A, B


Back to Product Lineup


Inhibition of Protein Phosphatase 2A

[Date : October 09 2025 00:07]

Detail Product Name Product Code Supplier Size Price
Cytostatin (Sodium Salt), Protein Phosphatase 2A (PP2A) Inhibitor
DatasheetThis may not be the latest data sheet. 		10664 IMCInstitute of Microbial Chemistry 1 mg $500

Description M.W.: 450.444 (sodium salt) Purity : >75% (HPLC) Molecular Formula : C21H32O7P Na Solubility : Soluble in MeOH, DMSO, and H2O Insoluble in n-hexane Cytostatin inhibits the adhesion of B16 melanoma cells to laminin and collagen type IV), but does not to the adhesionto fibronectin. It inhibits protein phosphatase 2A in a non-competitive manner. This product is suppled as sodium salt form.
Storage -20°C CAS 457070-06-3 (sodium salt), 156856-30-3 (salt free form)
Link

Natural compound Product List
Cytostatin (sodium salt)

Rubratoxin A, Protein Phosphatase 2A (PP2A) Inhibitor
DatasheetThis may not be the latest data sheet. 		10663 IMCInstitute of Microbial Chemistry 1 mg $500

Description M.W.: 520.531 Purity : >95% (HPLC) Molecular Formula : C26H32O11 Solubility : Soluble in DMSO, acetone, CH3CN. Poorly soluble in hexane Rubratoxin A inhibits protein phosphatase 2A (PP2A) in a competitive manner, however it does not inhibit protein phosphatases, such as PP1A and PP2B. The bioactive compound shows cytotoxicity in cultured mammalian cells and induces overphosphorylation of PP2A substrate proteins.
Storage -20°C CAS 22467-31-8
Link

Rubratoxin A
Natural compound Product List

[Date : October 09 2025 00:07]

Cytostatin (Sodium Salt), Protein Phosphatase 2A (PP2A) Inhibitor

DatasheetThis may not be the latest data sheet.


  • Product Code: 10664
  • Supplier: IMC
  • Size: 1mg
  • Price: $500

Description M.W.: 450.444 (sodium salt) Purity : >75% (HPLC) Molecular Formula : C21H32O7P Na Solubility : Soluble in MeOH, DMSO, and H2O Insoluble in n-hexane Cytostatin inhibits the adhesion of B16 melanoma cells to laminin and collagen type IV), but does not to the adhesionto fibronectin. It inhibits protein phosphatase 2A in a non-competitive manner. This product is suppled as sodium salt form.
Storage -20°C CAS 457070-06-3 (sodium salt), 156856-30-3 (salt free form)
Link

Natural compound Product List
Cytostatin (sodium salt)

Rubratoxin A, Protein Phosphatase 2A (PP2A) Inhibitor

DatasheetThis may not be the latest data sheet.


  • Product Code: 10663
  • Supplier: IMC
  • Size: 1mg
  • Price: $500

Description M.W.: 520.531 Purity : >95% (HPLC) Molecular Formula : C26H32O11 Solubility : Soluble in DMSO, acetone, CH3CN. Poorly soluble in hexane Rubratoxin A inhibits protein phosphatase 2A (PP2A) in a competitive manner, however it does not inhibit protein phosphatases, such as PP1A and PP2B. The bioactive compound shows cytotoxicity in cultured mammalian cells and induces overphosphorylation of PP2A substrate proteins.
Storage -20°C CAS 22467-31-8
Link

Rubratoxin A
Natural compound Product List


Back to Product Lineup


Inhibition of Thymidylate Synthase

[Date : October 09 2025 00:07]

Detail Product Name Product Code Supplier Size Price
Vanoxonin, Thymidylate Synthase Inhibitor
DatasheetThis may not be the latest data sheet. 		10744 IMCInstitute of Microbial Chemistry 1 mg $500

Description M.W.: 427.41 Purity : > 80％ (HPLC) Molecular Formula : C18H25N3O9 Solubility : Soluble in MeOH, DMSO, Acetic acid, and H2O, Insoluble : EtOAc, Chloroform, and n-hexane. Vanoxonin is a natural product delivered from cell culture of Saccharopolyspora hirsuta MG245-CF2 as an inhibitor of thymidylate synthetase. Vanoxonin forms a complex with a vanadium (V5+) which exhibits a strong inhibition against the synthetase. Howeber, Vanoxonin alone shows weak inhibition (IC50: 200 µg/mL). Vanoxonin-V5+ complex also showed in vitro cytotoxic activity against L-1210 lymphatic leukemia cells (MIC: 25 μg/mL).
Storage -20°C CAS 86933-99-5
Link

Vanoxonin [CAS: 86933-99-5]

[Date : October 09 2025 00:07]

Vanoxonin, Thymidylate Synthase Inhibitor

DatasheetThis may not be the latest data sheet.


  • Product Code: 10744
  • Supplier: IMC
  • Size: 1mg
  • Price: $500

Description M.W.: 427.41 Purity : > 80％ (HPLC) Molecular Formula : C18H25N3O9 Solubility : Soluble in MeOH, DMSO, Acetic acid, and H2O, Insoluble : EtOAc, Chloroform, and n-hexane. Vanoxonin is a natural product delivered from cell culture of Saccharopolyspora hirsuta MG245-CF2 as an inhibitor of thymidylate synthetase. Vanoxonin forms a complex with a vanadium (V5+) which exhibits a strong inhibition against the synthetase. Howeber, Vanoxonin alone shows weak inhibition (IC50: 200 µg/mL). Vanoxonin-V5+ complex also showed in vitro cytotoxic activity against L-1210 lymphatic leukemia cells (MIC: 25 μg/mL).
Storage -20°C CAS 86933-99-5
Link

Vanoxonin [CAS: 86933-99-5]


Back to Product Lineup


Inhibition of Tyrosine Kinase

[Date : October 09 2025 00:07]

Detail Product Name Product Code Supplier Size Price
Erbstatin, Tyrosine Kinase Inhibitor (TKI)
DatasheetThis may not be the latest data sheet. 		14697 IMCInstitute of Microbial Chemistry 1 mg $500

Description M.W.: 179.175 Purity : > 98％ (HPLC) Molecular Formula : C9H9NO3 Solubility : Soluble in MeOH, DMSO, and Acetone, Insoluble: H2O, and Hexane. Erbstatin was isolated from the culture filtrate of Streptomyces sp. MH435-hF3 as an inhibitor of epidermal growth factor (EGF) receptor associated tyrosine kinase. It was reported that the natural compound inhibits receptor-type tyrosine kinases such as EGFR tyrosine kinase without inhibiting cAMP-dependent protein kinase or protein kinase C.
Storage -20°C CAS 100827-28-9
Link

Erbstatin

[Date : October 09 2025 00:07]

Erbstatin, Tyrosine Kinase Inhibitor (TKI)

DatasheetThis may not be the latest data sheet.


  • Product Code: 14697
  • Supplier: IMC
  • Size: 1mg
  • Price: $500

Description M.W.: 179.175 Purity : > 98％ (HPLC) Molecular Formula : C9H9NO3 Solubility : Soluble in MeOH, DMSO, and Acetone, Insoluble: H2O, and Hexane. Erbstatin was isolated from the culture filtrate of Streptomyces sp. MH435-hF3 as an inhibitor of epidermal growth factor (EGF) receptor associated tyrosine kinase. It was reported that the natural compound inhibits receptor-type tyrosine kinases such as EGFR tyrosine kinase without inhibiting cAMP-dependent protein kinase or protein kinase C.
Storage -20°C CAS 100827-28-9
Link

Erbstatin


Back to Product Lineup


Inhibition of Dopamine β-hydroxylase

[Date : October 09 2025 00:07]

Detail Product Name Product Code Supplier Size Price
Dopastin, Dopamine β-Hydroxylase Inhibitor
DatasheetThis may not be the latest data sheet. 		00381 IMCInstitute of Microbial Chemistry 1 mg $500

Description M.W.: 215.25 Purity : >90% (HPLC) Molecular Formula : C9H17N3O3 Solubility : Soluble in MeOH, butanol, acetone, and CHCl3 Insoluble in H2O, ethyl acetate, ether, and hexane. Dopastin was reported as a potent inhibitor of dopamine β-hydroxylase. The compound showed a significant hypotensive effect to spontaneously hypertensive rats.
Storage -20°C CAS 37134-80-8
Link

Dopastin

[Date : October 09 2025 00:07]

Dopastin, Dopamine β-Hydroxylase Inhibitor

DatasheetThis may not be the latest data sheet.


  • Product Code: 00381
  • Supplier: IMC
  • Size: 1mg
  • Price: $500

Description M.W.: 215.25 Purity : >90% (HPLC) Molecular Formula : C9H17N3O3 Solubility : Soluble in MeOH, butanol, acetone, and CHCl3 Insoluble in H2O, ethyl acetate, ether, and hexane. Dopastin was reported as a potent inhibitor of dopamine β-hydroxylase. The compound showed a significant hypotensive effect to spontaneously hypertensive rats.
Storage -20°C CAS 37134-80-8
Link

Dopastin


Back to Product Lineup


Inhibition of Heparanase

[Date : October 09 2025 00:07]

Detail Product Name Product Code Supplier Size Price
Heparastatin (Hydrochloride), SF4 Hydrochloride, Heparanase Inhibitor
DatasheetThis may not be the latest data sheet. 		11829 IMCInstitute of Microbial Chemistry 1 mg $500

Description Molecular Formula: C8H11F3N2O5・HCl, Molecular Weight: 308.64, Heparastatin (SF4) inhibits recombinant human heparanase from human melanoma A375M cells transfected with pBK-CMV expression vectors containing the heparanase cDNA with IC50 1.02μM.
Storage -20°C CAS 153758-26-0 (hydrochloride salt), 153758-25-9 (salt free form)
Link

Heparastatin (SF4) Hydrochloride

[Date : October 09 2025 00:07]

Heparastatin (Hydrochloride), SF4 Hydrochloride, Heparanase Inhibitor

DatasheetThis may not be the latest data sheet.


  • Product Code: 11829
  • Supplier: IMC
  • Size: 1mg
  • Price: $500

Description Molecular Formula: C8H11F3N2O5・HCl, Molecular Weight: 308.64, Heparastatin (SF4) inhibits recombinant human heparanase from human melanoma A375M cells transfected with pBK-CMV expression vectors containing the heparanase cDNA with IC50 1.02μM.
Storage -20°C CAS 153758-26-0 (hydrochloride salt), 153758-25-9 (salt free form)
Link

Heparastatin (SF4) Hydrochloride


Back to Product Lineup


Inhibition of Phospholipase A2

[Date : October 09 2025 00:07]

Detail Product Name Product Code Supplier Size Price
Plipastatin A1, Phospholipase Inhibitor
DatasheetThis may not be the latest data sheet. 		15170 IMCInstitute of Microbial Chemistry 1 mg $500

Description M.W.: 1463.736　Purity : >90 % (HPLC) Solubility : Soluble in H2O, MeOH and DMSO, Insoluble in acetone, ethyl acetate Plipastatin A1, a member of lipopeptide containing a C16 3-hydroxyl fatty acid and 11 amino acids,　was isolated as an inhibitor of phospholipase A2 from the fermentation broth of Bacillus cereus BMG302-fF67. ) It showed the inhibitory activity on phospholipase A2 (IC50: 2.9 μM), C (IC50: 1.3 μM) and D (IC50: 1.4 μM).
Storage -20°C CAS 103651-09-8
Link

Plipastatin A1 [CAS: 103651-09-8]

[Date : October 09 2025 00:07]

Plipastatin A1, Phospholipase Inhibitor

DatasheetThis may not be the latest data sheet.


  • Product Code: 15170
  • Supplier: IMC
  • Size: 1mg
  • Price: $500

Description M.W.: 1463.736　Purity : >90 % (HPLC) Solubility : Soluble in H2O, MeOH and DMSO, Insoluble in acetone, ethyl acetate Plipastatin A1, a member of lipopeptide containing a C16 3-hydroxyl fatty acid and 11 amino acids,　was isolated as an inhibitor of phospholipase A2 from the fermentation broth of Bacillus cereus BMG302-fF67. ) It showed the inhibitory activity on phospholipase A2 (IC50: 2.9 μM), C (IC50: 1.3 μM) and D (IC50: 1.4 μM).
Storage -20°C CAS 103651-09-8
Link

Plipastatin A1 [CAS: 103651-09-8]


Back to Product Lineup


Suppression GRP78 Upregulation

[Date : October 09 2025 00:07]

Detail Product Name Product Code Supplier Size Price
Piericidin A1, NADH:Ubiquinone Oxidoreductase Inhibitor
DatasheetThis may not be the latest data sheet. 		14688 IMCInstitute of Microbial Chemistry 3x1 mg $500

Description M.W.: 415.574 Purity : >90％ (HPLC) Molecular Formula : C25H37NO4 Supplied as: EtOH solution (1 mg/mL) Solubility : Soluble in MeOH, EtOH, hexane, and DMF, Hardly soluble in H2O. Piericidin A1 is a bioactive compound which is known as a specific inhibitor of the respiratory chain in the electron transport system. This compound inhibits functions of the respiratory chain by targeting to the ubiquinone binding site on the respiratory complex I (also known as NADH:ubiquinone oxidoreductase).
Storage -20°C,Dark Storage CAS 2738-64-9
Link

Piericidin A1

[Date : October 09 2025 00:07]

Piericidin A1, NADH:Ubiquinone Oxidoreductase Inhibitor

DatasheetThis may not be the latest data sheet.


  • Product Code: 14688
  • Supplier: IMC
  • Size: 3x1mg
  • Price: $500

Description M.W.: 415.574 Purity : >90％ (HPLC) Molecular Formula : C25H37NO4 Supplied as: EtOH solution (1 mg/mL) Solubility : Soluble in MeOH, EtOH, hexane, and DMF, Hardly soluble in H2O. Piericidin A1 is a bioactive compound which is known as a specific inhibitor of the respiratory chain in the electron transport system. This compound inhibits functions of the respiratory chain by targeting to the ubiquinone binding site on the respiratory complex I (also known as NADH:ubiquinone oxidoreductase).
Storage -20°C,Dark Storage CAS 2738-64-9
Link

Piericidin A1


Back to Product Lineup


Resistance to Trehalase

[Date : October 09 2025 00:07]

Detail Product Name Product Code Supplier Size Price
Lentztrehalose A, Trehalase Resistant
DatasheetThis may not be the latest data sheet. 		14678 IMCInstitute of Microbial Chemistry 25 mg $500

Description M.W.: 444.430 Purity : >80% (qNMR) Molecular Formula : C17H32O13 Solubility : Soluble in DMSO, MeOH, and H2O Insoluble in hexane Lentztrehalose A is a biologically stable analog of trehalose harboring resistance of treharease and various microbes which can degrade general trehalose. The trehalose analog shows trehalose like bioactivities, such as bone reinforcement and anti-obesity effect in a postmenopausal mouse model.
Storage -20°C CAS 1609356-99-1
Link

Lentztrehalose A
Lentztrehalose A and its analogues B, C

Lentztrehalose B, Trehalase Resistant
DatasheetThis may not be the latest data sheet. 		14679 IMCInstitute of Microbial Chemistry 25 mg $500

Description M.W.: 410.416 Purity : >80% (qNMR) Molecular Formula : C17H30O11 Solubility : Soluble in DMSO, MeOH, and H2O Insoluble in hexane Lentztrehalose B is a biologically stable analog of trehalose harboring resistance of treharease and various microbes which can degrade general trehalose. After the oral administration of the trehalose analog to mice, it showed much better blood concentration compared to that of trehalose.
Storage -20°C CAS 1808096-67-4
Link

Lentztrehalose B
Lentztrehalose A and its analogues B, C

Lentztrehalose C, Trehalase Resistant
DatasheetThis may not be the latest data sheet. 		14680 IMCInstitute of Microbial Chemistry 25 mg $500

Description M.W.: 426.415 Purity : >75% (qNMR) Molecular Formula : C17H30O12 Solubility : Soluble in DMSO, MeOH, and H2O Insoluble in hexane Lentztrehalose C is a biologically stable analog of trehalose harboring resistance of treharease and various microbes which can degrade general trehalose. After the oral administration of the trehalose analog to mice, it showed much better blood concentration compared to that of trehalose.
Storage -20°C CAS 1808096-68-5
Link

Lentztrehalose C
Lentztrehalose A and its analogues B, C

[Date : October 09 2025 00:07]

Lentztrehalose A, Trehalase Resistant

DatasheetThis may not be the latest data sheet.


  • Product Code: 14678
  • Supplier: IMC
  • Size: 25mg
  • Price: $500

Description M.W.: 444.430 Purity : >80% (qNMR) Molecular Formula : C17H32O13 Solubility : Soluble in DMSO, MeOH, and H2O Insoluble in hexane Lentztrehalose A is a biologically stable analog of trehalose harboring resistance of treharease and various microbes which can degrade general trehalose. The trehalose analog shows trehalose like bioactivities, such as bone reinforcement and anti-obesity effect in a postmenopausal mouse model.
Storage -20°C CAS 1609356-99-1
Link

Lentztrehalose A
Lentztrehalose A and its analogues B, C

Lentztrehalose B, Trehalase Resistant

DatasheetThis may not be the latest data sheet.


  • Product Code: 14679
  • Supplier: IMC
  • Size: 25mg
  • Price: $500

Description M.W.: 410.416 Purity : >80% (qNMR) Molecular Formula : C17H30O11 Solubility : Soluble in DMSO, MeOH, and H2O Insoluble in hexane Lentztrehalose B is a biologically stable analog of trehalose harboring resistance of treharease and various microbes which can degrade general trehalose. After the oral administration of the trehalose analog to mice, it showed much better blood concentration compared to that of trehalose.
Storage -20°C CAS 1808096-67-4
Link

Lentztrehalose B
Lentztrehalose A and its analogues B, C

Lentztrehalose C, Trehalase Resistant

DatasheetThis may not be the latest data sheet.


  • Product Code: 14680
  • Supplier: IMC
  • Size: 25mg
  • Price: $500

Description M.W.: 426.415 Purity : >75% (qNMR) Molecular Formula : C17H30O12 Solubility : Soluble in DMSO, MeOH, and H2O Insoluble in hexane Lentztrehalose C is a biologically stable analog of trehalose harboring resistance of treharease and various microbes which can degrade general trehalose. After the oral administration of the trehalose analog to mice, it showed much better blood concentration compared to that of trehalose.
Storage -20°C CAS 1808096-68-5
Link

Lentztrehalose C
Lentztrehalose A and its analogues B, C


Back to Product Lineup


Antitumor

[Date : October 09 2025 00:07]

Detail Product Name Product Code Supplier Size Price
Altemicidin, Acaricidal and Antitumor
DatasheetThis may not be the latest data sheet. 		12151 IMCInstitute of Microbial Chemistry 1 mg $500

Description M.W.: 376.384 Purity : >90% (HPLC) Molecular Formula : C13H20N4O7S Solubility : Soluble in H2O, Poorly soluble in MeOH, Insoluble in acetone, and hexane Altemicidin inhibited the growth of murine leukemia, and IMC carcinoma cells. In addition, this bioactive compound expressed inhibitory activity against Xanthomonas oryzae and 50% prevention value against two-spotted spider mites on kidney bean leaves at around 10 ppm.
Storage -20°C CAS 125399-82-8
Link

Altemicidin

Bactobolin A (hydrochloride), Antitumor, Antibacterial
DatasheetThis may not be the latest data sheet. 		08465 IMCInstitute of Microbial Chemistry 1 mg $500

Description M.W.: 419.680 (hydrochloride form) Purity : >95％ (HPLC) Molecular Formula : C14H20Cl2N2O6･HCl (hydrochloride form) Solubility : Soluble in H2O, DMSO, Bactobolin A is supplied as hydrochloride form. This bioactive compound has broad-spectrum antibacterial, antitumor, and antileukemia activities. It prolongs the survival period of mice bearing a mouse lymphocytic leukemia L1210 cell line. It is reported that bactobolin A binds to a site on the 70S ribosome.
Storage -20°C CAS 72615-20-4 (salt free form)
Link

Bactobolin A (hydrochloride)

Bisucaberin, Antitumor
DatasheetThis may not be the latest data sheet. 		14659 IMCInstitute of Microbial Chemistry 1 mg $500

Description M.W. : 400.476　Purity : > 98% (HPLC)　Solubility : Soluble in DMSO, Slightly soluble in methanol, Insoluble in Water Bisucaberin is a siderophore isolated from a culture broth of a marine bacterial strain identified as Alteromonas haloplanktis. Bisucaberin induces macrophage-mediated tumor cell lysis (co-cultured with nonactivated macrophages.
Storage -20°C CAS 112972-60-8
Link

Bisucaberin

COMC, Cytotoxic
DatasheetThis may not be the latest data sheet. 		14701 IMCInstitute of Microbial Chemistry 1 mg $500

Description M.W.: 194.230 Purity : >98% (HPLC) Molecular Formula : C11H14O3 Supplied as : Oil Solubility : Soluble in CH3CN, CHCl3, and DMSO, COMC is a synthetic analog with simplified structure of COTC (#14675) isolated from Streptomyces and its molecular weight (MW) is less than 200. It was reported that COMC showed 10 times or more potent activity against murine colon adenocarcinoma cell line MAC26 than COTC.
Storage -20°C CAS 106281-45-2
Link

COMC [CAS: 106281-45-2]

COTC, Glyoxalase-I Inhibitor
DatasheetThis may not be the latest data sheet. 		14675 IMCInstitute of Microbial Chemistry 1 mg $500

Description M.W.: 242.227 Purity : >90% (HPLC) Molecular Formula : C11H14O6 Solubility : Soluble in MeOH, DMSO, and H2O, Insoluble in hexane, blocks enzymatic activity of alkaline phosphodiesterase derived from murine lymphoblastoma L5178Y cells (IC50: 60ug/ml), glyoxylase I in rat liver crude (IC50: 1.8 mM), and in yeast (IC50: 1.4 mM)
Storage -20°C CAS 57449-30-6
Link

COTC

6-epi-COTC, Cytotoxic
DatasheetThis may not be the latest data sheet. 		14698 IMCInstitute of Microbial Chemistry 1 mg $500

Description M.W.: 242.227 Purity : >98% (HPLC) Molecular Formula : C11H14O6 Solubility : Soluble in H2O, DMSO, 6-epi-COTC was isolated from Streptomyces griseosporeus as same as COTC. This compound is a diastereomer of COTC and showed cytotoxic activity towards lung cancer cell lines A549 and H460.
Storage -20°C CAS 959150-61-9
Link

6-epi-COTC [CAS: 959150-61-9]

Forphenicinol, Immunomodifier
DatasheetThis may not be the latest data sheet. 		09637 IMCInstitute of Microbial Chemistry 1 mg $500

Description M.W.: 197.190 Purity : >98% (HPLC) Molecular Formula : C9H11NO4 Solubility : Soluble in MeOH, DMSO, and H2O Insoluble in hexane. Forphenicinol is a synthesized derivative of forphenicine, the inhibitor of alkaline phosphatase produced by Streptomyces. The compound does not have inhibitory activity to alkaline phosphatase. It exhibits biological activities such as enhanced delayed hypersensitivity, enhanced macrophage phagocytosis, antitumor effects on transplanted tumors, and enhanced resistance to Pseudomonas aeruginosa infection in mice, while being extremely low toxicity.
Storage -20°C CAS 71522-58-2
Link

Forphenicinol

Inostamycin A (Sodium Salt), Antitumor
DatasheetThis may not be the latest data sheet. 		14652 IMCInstitute of Microbial Chemistry 1 mg $500

Description M.W.: 722.933 (Sodium salt) Purity : >90% (qNMR) Molecular Formula : C38H68O11Na (Sodium salt) Solubility : Soluble in DMSO, DMF, and CHCl3, Poorly soluble in H2O Inostamycin A is an inhibitor of phosphatidylinositol turnover, supplied as sodium salt. It was reported that this compound inhibited EGF-induced inositol incorporation into inositol lipids in the A431 cell assay system. It was also reported that inhibition of in vitro CDP-DG: inositol transferase activity of the A431 cell membrane, antimicrobial activities against gram-positive bacteria, cytocidal activity against srk-NIH-3T3, and potentiated colchicine cytotoxicity toward KB-C4 cells. In addition, it caused Ms-1 cell to accumulate in the G1 phase and induced morphological apoptosis at high concentration.
Storage -20°C CAS 1884611-95-3 (sodium salt), 129905-10-8 (salt free form)
Link

Inostamycin A (sodium salt)

Iturin A-2, Antifungal Antitumor
DatasheetThis may not be the latest data sheet. 		15171 IMCInstitute of Microbial Chemistry 1 mg $500

Description M.W.: 1,043.190 Purity : >90％ (HPLC) Molecular Formula : C48H74N12O14 Solubility : Soluble in MeOH, DMSO, and DMF Insoluble in H2O. Iturin A-2 is a cyclic polypeptide with antifungal activity. It was reported that the bioactive compound showed suppression of damping-off of tomato (a seeding disease) and cytotoxicity to human breast cancer cell line BT-474. Pharmacophore mapping studies suggested that the angiotensin-converting enzyme 2 (ACE2) as one of the potential targets of iturin A-2. This finding indicates that these lipopeptides may bind to SARS-CoV-2 nsp12 (RNA-dependent RNA polymerase) efficiently.
Storage -20°C CAS 83785-07-3
Link

Iturin A-2 [CAS: 83785-07-3]

Lentztrehalose A, Trehalase Resistant
DatasheetThis may not be the latest data sheet. 		14678 IMCInstitute of Microbial Chemistry 25 mg $500

Description M.W.: 444.430 Purity : >80% (qNMR) Molecular Formula : C17H32O13 Solubility : Soluble in DMSO, MeOH, and H2O Insoluble in hexane Lentztrehalose A is a biologically stable analog of trehalose harboring resistance of treharease and various microbes which can degrade general trehalose. The trehalose analog shows trehalose like bioactivities, such as bone reinforcement and anti-obesity effect in a postmenopausal mouse model.
Storage -20°C CAS 1609356-99-1
Link

Lentztrehalose A
Lentztrehalose A and its analogues B, C

Migrastatin, Tumor Cell Migration Inhibitor, Antitumor
DatasheetThis may not be the latest data sheet. 		10708 IMCInstitute of Microbial Chemistry 1 mg $500

Description M.W.: 489.609 Purity : >98% (HPLC) Molecular Formula : C27H39NO7 Solubility : Soluble in MeOH, DMSO, and DMF, Insoluble in H2O. Migrastatin was reported that inhibitory activities against tumor cell proliferation, metastasis of human esophageal cancer cells, anchorage-independent growth of human small cell lung carcinoma (Ms-1) cells.
Storage -20°C CAS 314245-65-3
Link

Migrastatin

Oxanosine, Antitumor, GMP Synthase Inhibitor
DatasheetThis may not be the latest data sheet. 		00762 IMCInstitute of Microbial Chemistry 1 mg $500

Description M.W.: 284.23 Purity : > 98％ (HPLC) Molecular Formula : C10H12N4O6 Solubility : Soluble in H2O, Methanol, and DMSO, Insoluble in CHCl3. Inhibitory activity of leukemia L210 : IC50=1.0 μg/ml, Competitive inhibitory activity of GMP synthase : Ki=7.4x10-4 M. Oxanosine was isolated from culture broth of Streptomyces capreolus MG265-CF3 and was reported as a novel nucleoside. It was also reported that this compound has an inhibitory activity of HIV replication and leukemia L1210 cell growth.
Storage -20°C CAS 80394-72-5
Link

Oxanosine

[Date : October 09 2025 00:07]

Altemicidin, Acaricidal and Antitumor

DatasheetThis may not be the latest data sheet.


  • Product Code: 12151
  • Supplier: IMC
  • Size: 1mg
  • Price: $500

Description M.W.: 376.384 Purity : >90% (HPLC) Molecular Formula : C13H20N4O7S Solubility : Soluble in H2O, Poorly soluble in MeOH, Insoluble in acetone, and hexane Altemicidin inhibited the growth of murine leukemia, and IMC carcinoma cells. In addition, this bioactive compound expressed inhibitory activity against Xanthomonas oryzae and 50% prevention value against two-spotted spider mites on kidney bean leaves at around 10 ppm.
Storage -20°C CAS 125399-82-8
Link

Altemicidin

Bactobolin A (hydrochloride), Antitumor, Antibacterial

DatasheetThis may not be the latest data sheet.


  • Product Code: 08465
  • Supplier: IMC
  • Size: 1mg
  • Price: $500

Description M.W.: 419.680 (hydrochloride form) Purity : >95％ (HPLC) Molecular Formula : C14H20Cl2N2O6･HCl (hydrochloride form) Solubility : Soluble in H2O, DMSO, Bactobolin A is supplied as hydrochloride form. This bioactive compound has broad-spectrum antibacterial, antitumor, and antileukemia activities. It prolongs the survival period of mice bearing a mouse lymphocytic leukemia L1210 cell line. It is reported that bactobolin A binds to a site on the 70S ribosome.
Storage -20°C CAS 72615-20-4 (salt free form)
Link

Bactobolin A (hydrochloride)

Bisucaberin, Antitumor

DatasheetThis may not be the latest data sheet.


  • Product Code: 14659
  • Supplier: IMC
  • Size: 1mg
  • Price: $500

Description M.W. : 400.476　Purity : > 98% (HPLC)　Solubility : Soluble in DMSO, Slightly soluble in methanol, Insoluble in Water Bisucaberin is a siderophore isolated from a culture broth of a marine bacterial strain identified as Alteromonas haloplanktis. Bisucaberin induces macrophage-mediated tumor cell lysis (co-cultured with nonactivated macrophages.
Storage -20°C CAS 112972-60-8
Link

Bisucaberin

COMC, Cytotoxic

DatasheetThis may not be the latest data sheet.


  • Product Code: 14701
  • Supplier: IMC
  • Size: 1mg
  • Price: $500

Description M.W.: 194.230 Purity : >98% (HPLC) Molecular Formula : C11H14O3 Supplied as : Oil Solubility : Soluble in CH3CN, CHCl3, and DMSO, COMC is a synthetic analog with simplified structure of COTC (#14675) isolated from Streptomyces and its molecular weight (MW) is less than 200. It was reported that COMC showed 10 times or more potent activity against murine colon adenocarcinoma cell line MAC26 than COTC.
Storage -20°C CAS 106281-45-2
Link

COMC [CAS: 106281-45-2]

COTC, Glyoxalase-I Inhibitor

DatasheetThis may not be the latest data sheet.


  • Product Code: 14675
  • Supplier: IMC
  • Size: 1mg
  • Price: $500

Description M.W.: 242.227 Purity : >90% (HPLC) Molecular Formula : C11H14O6 Solubility : Soluble in MeOH, DMSO, and H2O, Insoluble in hexane, blocks enzymatic activity of alkaline phosphodiesterase derived from murine lymphoblastoma L5178Y cells (IC50: 60ug/ml), glyoxylase I in rat liver crude (IC50: 1.8 mM), and in yeast (IC50: 1.4 mM)
Storage -20°C CAS 57449-30-6
Link

COTC

6-epi-COTC, Cytotoxic

DatasheetThis may not be the latest data sheet.


  • Product Code: 14698
  • Supplier: IMC
  • Size: 1mg
  • Price: $500

Description M.W.: 242.227 Purity : >98% (HPLC) Molecular Formula : C11H14O6 Solubility : Soluble in H2O, DMSO, 6-epi-COTC was isolated from Streptomyces griseosporeus as same as COTC. This compound is a diastereomer of COTC and showed cytotoxic activity towards lung cancer cell lines A549 and H460.
Storage -20°C CAS 959150-61-9
Link

6-epi-COTC [CAS: 959150-61-9]

Forphenicinol, Immunomodifier

DatasheetThis may not be the latest data sheet.


  • Product Code: 09637
  • Supplier: IMC
  • Size: 1mg
  • Price: $500

Description M.W.: 197.190 Purity : >98% (HPLC) Molecular Formula : C9H11NO4 Solubility : Soluble in MeOH, DMSO, and H2O Insoluble in hexane. Forphenicinol is a synthesized derivative of forphenicine, the inhibitor of alkaline phosphatase produced by Streptomyces. The compound does not have inhibitory activity to alkaline phosphatase. It exhibits biological activities such as enhanced delayed hypersensitivity, enhanced macrophage phagocytosis, antitumor effects on transplanted tumors, and enhanced resistance to Pseudomonas aeruginosa infection in mice, while being extremely low toxicity.
Storage -20°C CAS 71522-58-2
Link

Forphenicinol

Inostamycin A (Sodium Salt), Antitumor

DatasheetThis may not be the latest data sheet.


  • Product Code: 14652
  • Supplier: IMC
  • Size: 1mg
  • Price: $500

Description M.W.: 722.933 (Sodium salt) Purity : >90% (qNMR) Molecular Formula : C38H68O11Na (Sodium salt) Solubility : Soluble in DMSO, DMF, and CHCl3, Poorly soluble in H2O Inostamycin A is an inhibitor of phosphatidylinositol turnover, supplied as sodium salt. It was reported that this compound inhibited EGF-induced inositol incorporation into inositol lipids in the A431 cell assay system. It was also reported that inhibition of in vitro CDP-DG: inositol transferase activity of the A431 cell membrane, antimicrobial activities against gram-positive bacteria, cytocidal activity against srk-NIH-3T3, and potentiated colchicine cytotoxicity toward KB-C4 cells. In addition, it caused Ms-1 cell to accumulate in the G1 phase and induced morphological apoptosis at high concentration.
Storage -20°C CAS 1884611-95-3 (sodium salt), 129905-10-8 (salt free form)
Link

Inostamycin A (sodium salt)

Iturin A-2, Antifungal Antitumor

DatasheetThis may not be the latest data sheet.


  • Product Code: 15171
  • Supplier: IMC
  • Size: 1mg
  • Price: $500

Description M.W.: 1,043.190 Purity : >90％ (HPLC) Molecular Formula : C48H74N12O14 Solubility : Soluble in MeOH, DMSO, and DMF Insoluble in H2O. Iturin A-2 is a cyclic polypeptide with antifungal activity. It was reported that the bioactive compound showed suppression of damping-off of tomato (a seeding disease) and cytotoxicity to human breast cancer cell line BT-474. Pharmacophore mapping studies suggested that the angiotensin-converting enzyme 2 (ACE2) as one of the potential targets of iturin A-2. This finding indicates that these lipopeptides may bind to SARS-CoV-2 nsp12 (RNA-dependent RNA polymerase) efficiently.
Storage -20°C CAS 83785-07-3
Link

Iturin A-2 [CAS: 83785-07-3]

Lentztrehalose A, Trehalase Resistant

DatasheetThis may not be the latest data sheet.


  • Product Code: 14678
  • Supplier: IMC
  • Size: 25mg
  • Price: $500

Description M.W.: 444.430 Purity : >80% (qNMR) Molecular Formula : C17H32O13 Solubility : Soluble in DMSO, MeOH, and H2O Insoluble in hexane Lentztrehalose A is a biologically stable analog of trehalose harboring resistance of treharease and various microbes which can degrade general trehalose. The trehalose analog shows trehalose like bioactivities, such as bone reinforcement and anti-obesity effect in a postmenopausal mouse model.
Storage -20°C CAS 1609356-99-1
Link

Lentztrehalose A
Lentztrehalose A and its analogues B, C

Migrastatin, Tumor Cell Migration Inhibitor, Antitumor

DatasheetThis may not be the latest data sheet.


  • Product Code: 10708
  • Supplier: IMC
  • Size: 1mg
  • Price: $500

Description M.W.: 489.609 Purity : >98% (HPLC) Molecular Formula : C27H39NO7 Solubility : Soluble in MeOH, DMSO, and DMF, Insoluble in H2O. Migrastatin was reported that inhibitory activities against tumor cell proliferation, metastasis of human esophageal cancer cells, anchorage-independent growth of human small cell lung carcinoma (Ms-1) cells.
Storage -20°C CAS 314245-65-3
Link

Migrastatin

Oxanosine, Antitumor, GMP Synthase Inhibitor

DatasheetThis may not be the latest data sheet.


  • Product Code: 00762
  • Supplier: IMC
  • Size: 1mg
  • Price: $500

Description M.W.: 284.23 Purity : > 98％ (HPLC) Molecular Formula : C10H12N4O6 Solubility : Soluble in H2O, Methanol, and DMSO, Insoluble in CHCl3. Inhibitory activity of leukemia L210 : IC50=1.0 μg/ml, Competitive inhibitory activity of GMP synthase : Ki=7.4x10-4 M. Oxanosine was isolated from culture broth of Streptomyces capreolus MG265-CF3 and was reported as a novel nucleoside. It was also reported that this compound has an inhibitory activity of HIV replication and leukemia L1210 cell growth.
Storage -20°C CAS 80394-72-5
Link

Oxanosine


Back to Product Lineup


Metastasis Control

[Date : October 09 2025 00:07]

Detail Product Name Product Code Supplier Size Price
Migrastatin, Tumor Cell Migration Inhibitor, Antitumor
DatasheetThis may not be the latest data sheet. 		10708 IMCInstitute of Microbial Chemistry 1 mg $500

Description M.W.: 489.609 Purity : >98% (HPLC) Molecular Formula : C27H39NO7 Solubility : Soluble in MeOH, DMSO, and DMF, Insoluble in H2O. Migrastatin was reported that inhibitory activities against tumor cell proliferation, metastasis of human esophageal cancer cells, anchorage-independent growth of human small cell lung carcinoma (Ms-1) cells.
Storage -20°C CAS 314245-65-3
Link

Migrastatin

[Date : October 09 2025 00:07]

Migrastatin, Tumor Cell Migration Inhibitor, Antitumor

DatasheetThis may not be the latest data sheet.


  • Product Code: 10708
  • Supplier: IMC
  • Size: 1mg
  • Price: $500

Description M.W.: 489.609 Purity : >98% (HPLC) Molecular Formula : C27H39NO7 Solubility : Soluble in MeOH, DMSO, and DMF, Insoluble in H2O. Migrastatin was reported that inhibitory activities against tumor cell proliferation, metastasis of human esophageal cancer cells, anchorage-independent growth of human small cell lung carcinoma (Ms-1) cells.
Storage -20°C CAS 314245-65-3
Link

Migrastatin


Back to Product Lineup


Antimicrobe (gram-Positive & Negative)

[Date : October 09 2025 00:07]

Detail Product Name Product Code Supplier Size Price
Althiomycin, Bacterial Protein Synthesis Inhibitor, Antibacterial (Gram-Positive & Negative)
DatasheetThis may not be the latest data sheet. 		14660 IMCInstitute of Microbial Chemistry 1 mg $500

Description M.W.: 439.461 Purity : >98% (HPLC) Molecular Formula : C16H17N5O6S2 Solubility : Soluble in 2-ethoxy ethanol (ethyl cellosolve), pyridine, and DMSO. Poorly soluble in MeOH, EtOAc, and acetone. Insoluble in H2O. Althiomycin is a sulfur containing peptide antibiotic obtained from Streptomyces. This natural compound is active against both gram-positive and-negative bacteria and inhibits protein synthesis in both intact cells and cell-free system of E. coli.
Storage -20°C CAS 12656-40-5
Link

Althiomycin

Bactobolin A (hydrochloride), Antitumor, Antibacterial
DatasheetThis may not be the latest data sheet. 		08465 IMCInstitute of Microbial Chemistry 1 mg $500

Description M.W.: 419.680 (hydrochloride form) Purity : >95％ (HPLC) Molecular Formula : C14H20Cl2N2O6･HCl (hydrochloride form) Solubility : Soluble in H2O, DMSO, Bactobolin A is supplied as hydrochloride form. This bioactive compound has broad-spectrum antibacterial, antitumor, and antileukemia activities. It prolongs the survival period of mice bearing a mouse lymphocytic leukemia L1210 cell line. It is reported that bactobolin A binds to a site on the 70S ribosome.
Storage -20°C CAS 72615-20-4 (salt free form)
Link

Bactobolin A (hydrochloride)

Cyclamidomycin, Nucleoside Diphosphate Kinase (NDPK) Inhibitor, Antibacterial (Gram-Positive & Negative)
DatasheetThis may not be the latest data sheet. 		01541 IMCInstitute of Microbial Chemistry 1 mg $500

Description M.W.: 138.17 Purity : > 98％ (HPLC) Molecular Formula : C7H10N2O Solubility : Soluble in H2O, Insoluble : Hexane, and MeOH. Cyclamidomycin (synonyms: Desdanine) is isolated from cultures of Streptomyces sp.MA130-A1. It is reported that this compound inhibited nucleoside diphosphate kinase of Escherichia coli and growth of gram-positive and gram-negative bacteria. In addition, cyclamidomycin inhibited plaque formation of male-specific coliphages and suppress the multiplication of both RNA phage Qβ and filamentous DNA phage f1.
Storage -20°C CAS 35663-85-5
Link

Cyclamidomycin

Negamycin (Hydrochloride), Antibacterial (Gram-Positive & Negative), Bacterial Protein Synthesis Inhibitor
DatasheetThis may not be the latest data sheet. 		14662 IMCInstitute of Microbial Chemistry 5 mg $500

Description M.W.: 284.741（mono HCl salt） Purity : >80% (qNMR) Molecular Formula : C9H20N4O4･HCl Solubility : Soluble in DMSO, Insoluble in hexane Negamycin exhibits anti-bacterial activity against gram-positive and gram-negative bacteria including multidrug-resistant Pseudomonas and cause inhibition of protein synthesis by interacting helix 34 (h34) element of 16S rRNA. This product is supplied as HCl salt.
Storage -20°C CAS 33404-78-3 (salt free form)
Link

Negamycin (hydrochloride)

[Date : October 09 2025 00:07]

Althiomycin, Bacterial Protein Synthesis Inhibitor, Antibacterial (Gram-Positive & Negative)

DatasheetThis may not be the latest data sheet.


  • Product Code: 14660
  • Supplier: IMC
  • Size: 1mg
  • Price: $500

Description M.W.: 439.461 Purity : >98% (HPLC) Molecular Formula : C16H17N5O6S2 Solubility : Soluble in 2-ethoxy ethanol (ethyl cellosolve), pyridine, and DMSO. Poorly soluble in MeOH, EtOAc, and acetone. Insoluble in H2O. Althiomycin is a sulfur containing peptide antibiotic obtained from Streptomyces. This natural compound is active against both gram-positive and-negative bacteria and inhibits protein synthesis in both intact cells and cell-free system of E. coli.
Storage -20°C CAS 12656-40-5
Link

Althiomycin

Bactobolin A (hydrochloride), Antitumor, Antibacterial

DatasheetThis may not be the latest data sheet.


  • Product Code: 08465
  • Supplier: IMC
  • Size: 1mg
  • Price: $500

Description M.W.: 419.680 (hydrochloride form) Purity : >95％ (HPLC) Molecular Formula : C14H20Cl2N2O6･HCl (hydrochloride form) Solubility : Soluble in H2O, DMSO, Bactobolin A is supplied as hydrochloride form. This bioactive compound has broad-spectrum antibacterial, antitumor, and antileukemia activities. It prolongs the survival period of mice bearing a mouse lymphocytic leukemia L1210 cell line. It is reported that bactobolin A binds to a site on the 70S ribosome.
Storage -20°C CAS 72615-20-4 (salt free form)
Link

Bactobolin A (hydrochloride)

Cyclamidomycin, Nucleoside Diphosphate Kinase (NDPK) Inhibitor, Antibacterial (Gram-Positive & Negative)

DatasheetThis may not be the latest data sheet.


  • Product Code: 01541
  • Supplier: IMC
  • Size: 1mg
  • Price: $500

Description M.W.: 138.17 Purity : > 98％ (HPLC) Molecular Formula : C7H10N2O Solubility : Soluble in H2O, Insoluble : Hexane, and MeOH. Cyclamidomycin (synonyms: Desdanine) is isolated from cultures of Streptomyces sp.MA130-A1. It is reported that this compound inhibited nucleoside diphosphate kinase of Escherichia coli and growth of gram-positive and gram-negative bacteria. In addition, cyclamidomycin inhibited plaque formation of male-specific coliphages and suppress the multiplication of both RNA phage Qβ and filamentous DNA phage f1.
Storage -20°C CAS 35663-85-5
Link

Cyclamidomycin

Negamycin (Hydrochloride), Antibacterial (Gram-Positive & Negative), Bacterial Protein Synthesis Inhibitor

DatasheetThis may not be the latest data sheet.


  • Product Code: 14662
  • Supplier: IMC
  • Size: 5mg
  • Price: $500

Description M.W.: 284.741（mono HCl salt） Purity : >80% (qNMR) Molecular Formula : C9H20N4O4･HCl Solubility : Soluble in DMSO, Insoluble in hexane Negamycin exhibits anti-bacterial activity against gram-positive and gram-negative bacteria including multidrug-resistant Pseudomonas and cause inhibition of protein synthesis by interacting helix 34 (h34) element of 16S rRNA. This product is supplied as HCl salt.
Storage -20°C CAS 33404-78-3 (salt free form)
Link

Negamycin (hydrochloride)


Back to Product Lineup


Anti-gram Positive Bacteria

[Date : October 09 2025 00:07]

Detail Product Name Product Code Supplier Size Price
Bottromycin A2, Antibacterial (Gram-Positive)
DatasheetThis may not be the latest data sheet. 		00592 IMCInstitute of Microbial Chemistry 1 mg $500

Description M.W.: 823.06 Purity : > 80％ (HPLC) Molecular Formula : C42H62N8O7S Solubility : Soluble in H2O, Methanol, and Ether, Insoluble in n-Hexane. Bottromycin A2 has a cyclic peptide structure and shows inhibitory activity against gram-positive bacteria. It is also reported to have low toxicity but strong antibacterial activity against drug-resistant bacteria, such as against MRSA(Methicillin-Resistant Staphylococcus Aureus) and VRE(Vancomycin-Resistant enterococci). The mechanism of Bottromycin A2 is known to inhibit bacterial protein synthesis by binding to the A-site of ribosome and blocking aminoacyl-tRNA binding.
Storage -20°C CAS 15005-62-6
Link

Bottromycin A2

[Date : October 09 2025 00:07]

Bottromycin A2, Antibacterial (Gram-Positive)

DatasheetThis may not be the latest data sheet.


  • Product Code: 00592
  • Supplier: IMC
  • Size: 1mg
  • Price: $500

Description M.W.: 823.06 Purity : > 80％ (HPLC) Molecular Formula : C42H62N8O7S Solubility : Soluble in H2O, Methanol, and Ether, Insoluble in n-Hexane. Bottromycin A2 has a cyclic peptide structure and shows inhibitory activity against gram-positive bacteria. It is also reported to have low toxicity but strong antibacterial activity against drug-resistant bacteria, such as against MRSA(Methicillin-Resistant Staphylococcus Aureus) and VRE(Vancomycin-Resistant enterococci). The mechanism of Bottromycin A2 is known to inhibit bacterial protein synthesis by binding to the A-site of ribosome and blocking aminoacyl-tRNA binding.
Storage -20°C CAS 15005-62-6
Link

Bottromycin A2


Back to Product Lineup


Anti-MRSA, Anti-VRE

[Date : October 09 2025 00:07]

Detail Product Name Product Code Supplier Size Price
Bottromycin A2, Antibacterial (Gram-Positive)
DatasheetThis may not be the latest data sheet. 		00592 IMCInstitute of Microbial Chemistry 1 mg $500

Description M.W.: 823.06 Purity : > 80％ (HPLC) Molecular Formula : C42H62N8O7S Solubility : Soluble in H2O, Methanol, and Ether, Insoluble in n-Hexane. Bottromycin A2 has a cyclic peptide structure and shows inhibitory activity against gram-positive bacteria. It is also reported to have low toxicity but strong antibacterial activity against drug-resistant bacteria, such as against MRSA(Methicillin-Resistant Staphylococcus Aureus) and VRE(Vancomycin-Resistant enterococci). The mechanism of Bottromycin A2 is known to inhibit bacterial protein synthesis by binding to the A-site of ribosome and blocking aminoacyl-tRNA binding.
Storage -20°C CAS 15005-62-6
Link

Bottromycin A2

[Date : October 09 2025 00:07]

Bottromycin A2, Antibacterial (Gram-Positive)

DatasheetThis may not be the latest data sheet.


  • Product Code: 00592
  • Supplier: IMC
  • Size: 1mg
  • Price: $500

Description M.W.: 823.06 Purity : > 80％ (HPLC) Molecular Formula : C42H62N8O7S Solubility : Soluble in H2O, Methanol, and Ether, Insoluble in n-Hexane. Bottromycin A2 has a cyclic peptide structure and shows inhibitory activity against gram-positive bacteria. It is also reported to have low toxicity but strong antibacterial activity against drug-resistant bacteria, such as against MRSA(Methicillin-Resistant Staphylococcus Aureus) and VRE(Vancomycin-Resistant enterococci). The mechanism of Bottromycin A2 is known to inhibit bacterial protein synthesis by binding to the A-site of ribosome and blocking aminoacyl-tRNA binding.
Storage -20°C CAS 15005-62-6
Link

Bottromycin A2


Back to Product Lineup


Anti-Resporatory Infectious Bacteria

[Date : October 09 2025 00:07]

Detail Product Name Product Code Supplier Size Price
Forphenicinol, Immunomodifier
DatasheetThis may not be the latest data sheet. 		09637 IMCInstitute of Microbial Chemistry 1 mg $500

Description M.W.: 197.190 Purity : >98% (HPLC) Molecular Formula : C9H11NO4 Solubility : Soluble in MeOH, DMSO, and H2O Insoluble in hexane. Forphenicinol is a synthesized derivative of forphenicine, the inhibitor of alkaline phosphatase produced by Streptomyces. The compound does not have inhibitory activity to alkaline phosphatase. It exhibits biological activities such as enhanced delayed hypersensitivity, enhanced macrophage phagocytosis, antitumor effects on transplanted tumors, and enhanced resistance to Pseudomonas aeruginosa infection in mice, while being extremely low toxicity.
Storage -20°C CAS 71522-58-2
Link

Forphenicinol

[Date : October 09 2025 00:07]

Forphenicinol, Immunomodifier

DatasheetThis may not be the latest data sheet.


  • Product Code: 09637
  • Supplier: IMC
  • Size: 1mg
  • Price: $500

Description M.W.: 197.190 Purity : >98% (HPLC) Molecular Formula : C9H11NO4 Solubility : Soluble in MeOH, DMSO, and H2O Insoluble in hexane. Forphenicinol is a synthesized derivative of forphenicine, the inhibitor of alkaline phosphatase produced by Streptomyces. The compound does not have inhibitory activity to alkaline phosphatase. It exhibits biological activities such as enhanced delayed hypersensitivity, enhanced macrophage phagocytosis, antitumor effects on transplanted tumors, and enhanced resistance to Pseudomonas aeruginosa infection in mice, while being extremely low toxicity.
Storage -20°C CAS 71522-58-2
Link

Forphenicinol


Back to Product Lineup


Acid-Fast Bacillus Growth Suppression

[Date : October 09 2025 00:07]

Detail Product Name Product Code Supplier Size Price
Minosaminomicin, Bacterial Protein Synthesis Inhibitor
DatasheetThis may not be the latest data sheet. 		02872 IMCInstitute of Microbial Chemistry 1 mg $500

Description M.W.: 618.689 Purity : >98％ (HPLC) Molecular Formula : C25H46N8O10 Solubility : Soluble in MeOH, DMSO, and H2O, Insoluble in Hexane. Minosaminomycin inhibits phage f2 RNA-directed protein synthesis in a cell-free system of Escherichia coli by 50% at 0.2 µM. It was also reported that minimum inhibitory concentrations of the bioactive compound were determined as 1.56 µg/ml for Mycobacterium smegmatis ATCC 607 and 6.25 µg/ml for Mycobacterium phlei, respectively.
Storage -20°C CAS 51746-09-9
Link

Minosaminomycin

[Date : October 09 2025 00:07]

Minosaminomicin, Bacterial Protein Synthesis Inhibitor

DatasheetThis may not be the latest data sheet.


  • Product Code: 02872
  • Supplier: IMC
  • Size: 1mg
  • Price: $500

Description M.W.: 618.689 Purity : >98％ (HPLC) Molecular Formula : C25H46N8O10 Solubility : Soluble in MeOH, DMSO, and H2O, Insoluble in Hexane. Minosaminomycin inhibits phage f2 RNA-directed protein synthesis in a cell-free system of Escherichia coli by 50% at 0.2 µM. It was also reported that minimum inhibitory concentrations of the bioactive compound were determined as 1.56 µg/ml for Mycobacterium smegmatis ATCC 607 and 6.25 µg/ml for Mycobacterium phlei, respectively.
Storage -20°C CAS 51746-09-9
Link

Minosaminomycin


Back to Product Lineup


Antifungal

[Date : October 09 2025 00:07]

Detail Product Name Product Code Supplier Size Price
Benanomicin A, Antifungal via Binding to Mannan
DatasheetThis may not be the latest data sheet. 		02966 IMCInstitute of Microbial Chemistry 1 mg $500

Description M.W.: 827.74 Purity : > 90％ (HPLC) Molecular Formula : C39H41NO19 Solubility : Soluble in DMSO and DMF, Poorly soluble in MeOH and CHCl3 Insoluble in H2O, Antimicrobial activity (MIC) : Cryptococcus neoformans F-10 0.6~1.25 μg/ml, Cryptococcus laurenti 0.63 μg/ml, Rhodotorula rubra 0.63 μg/ml, Tricosporon cutaneum 1.25~5 μg/ml. Benanomicin A is isolated from Actinomadura sp. MH193-16F4. This compound exhibits excellent therapeutic efficacy against in a Pneumocystis carinii-infected mouse model by intraperitoneal administration at 10mg/kg/day. In addition, this compound also has antimycotic activities via binding to mannan in the cell walls of fungi. It is recently reported that this compound has been utilized to prepare mannan cell walls by the lectin-like functionality of it.
Storage -20°C CAS 116249-65-1
Link

Benanomicin A

Benanomicin B, Antifungal
DatasheetThis may not be the latest data sheet. 		02968 IMCInstitute of Microbial Chemistry 1 mg $500

Description M.W.: 826.761 Purity : > 90％ (HPLC) Molecular Formula : C39H42N2O18 Solubility : Soluble in DMSO, Insoluble in H2O, Antimicrobial activity (MIC) : Cryptococcus neoformans F-10 1.56 μg/ml, Candida pseudotropicalis F-2 6.25 μg/ml, Candida kusei F-5 6.25 μg/ml, Candida sp. Yu-1200 6.25 μg/ml, Saccharomyces cerevisiae F-7 6.25 μg/ml. Benanomicin B is an antibiotic isolated from the culture fluid of Actinomadura sp. MH193-16F4. This compound prevented HIV-1 infection to human T-cells and syncytium formation. In addition, the natural compound is also reported antifungal and antibacterial activities against Candida, Cryptococcus and Saccharomyces, etc.
Storage -20°C CAS 116249-66-2 (free form)
Link

Benanomicin B

Iturin A-2, Antifungal Antitumor
DatasheetThis may not be the latest data sheet. 		15171 IMCInstitute of Microbial Chemistry 1 mg $500

Description M.W.: 1,043.190 Purity : >90％ (HPLC) Molecular Formula : C48H74N12O14 Solubility : Soluble in MeOH, DMSO, and DMF Insoluble in H2O. Iturin A-2 is a cyclic polypeptide with antifungal activity. It was reported that the bioactive compound showed suppression of damping-off of tomato (a seeding disease) and cytotoxicity to human breast cancer cell line BT-474. Pharmacophore mapping studies suggested that the angiotensin-converting enzyme 2 (ACE2) as one of the potential targets of iturin A-2. This finding indicates that these lipopeptides may bind to SARS-CoV-2 nsp12 (RNA-dependent RNA polymerase) efficiently.
Storage -20°C CAS 83785-07-3
Link

Iturin A-2 [CAS: 83785-07-3]

Plipastatin A1, Phospholipase Inhibitor
DatasheetThis may not be the latest data sheet. 		15170 IMCInstitute of Microbial Chemistry 1 mg $500

Description M.W.: 1463.736　Purity : >90 % (HPLC) Solubility : Soluble in H2O, MeOH and DMSO, Insoluble in acetone, ethyl acetate Plipastatin A1, a member of lipopeptide containing a C16 3-hydroxyl fatty acid and 11 amino acids,　was isolated as an inhibitor of phospholipase A2 from the fermentation broth of Bacillus cereus BMG302-fF67. ) It showed the inhibitory activity on phospholipase A2 (IC50: 2.9 μM), C (IC50: 1.3 μM) and D (IC50: 1.4 μM).
Storage -20°C CAS 103651-09-8
Link

Plipastatin A1 [CAS: 103651-09-8]

[Date : October 09 2025 00:07]

Benanomicin A, Antifungal via Binding to Mannan

DatasheetThis may not be the latest data sheet.


  • Product Code: 02966
  • Supplier: IMC
  • Size: 1mg
  • Price: $500

Description M.W.: 827.74 Purity : > 90％ (HPLC) Molecular Formula : C39H41NO19 Solubility : Soluble in DMSO and DMF, Poorly soluble in MeOH and CHCl3 Insoluble in H2O, Antimicrobial activity (MIC) : Cryptococcus neoformans F-10 0.6~1.25 μg/ml, Cryptococcus laurenti 0.63 μg/ml, Rhodotorula rubra 0.63 μg/ml, Tricosporon cutaneum 1.25~5 μg/ml. Benanomicin A is isolated from Actinomadura sp. MH193-16F4. This compound exhibits excellent therapeutic efficacy against in a Pneumocystis carinii-infected mouse model by intraperitoneal administration at 10mg/kg/day. In addition, this compound also has antimycotic activities via binding to mannan in the cell walls of fungi. It is recently reported that this compound has been utilized to prepare mannan cell walls by the lectin-like functionality of it.
Storage -20°C CAS 116249-65-1
Link

Benanomicin A

Benanomicin B, Antifungal

DatasheetThis may not be the latest data sheet.


  • Product Code: 02968
  • Supplier: IMC
  • Size: 1mg
  • Price: $500

Description M.W.: 826.761 Purity : > 90％ (HPLC) Molecular Formula : C39H42N2O18 Solubility : Soluble in DMSO, Insoluble in H2O, Antimicrobial activity (MIC) : Cryptococcus neoformans F-10 1.56 μg/ml, Candida pseudotropicalis F-2 6.25 μg/ml, Candida kusei F-5 6.25 μg/ml, Candida sp. Yu-1200 6.25 μg/ml, Saccharomyces cerevisiae F-7 6.25 μg/ml. Benanomicin B is an antibiotic isolated from the culture fluid of Actinomadura sp. MH193-16F4. This compound prevented HIV-1 infection to human T-cells and syncytium formation. In addition, the natural compound is also reported antifungal and antibacterial activities against Candida, Cryptococcus and Saccharomyces, etc.
Storage -20°C CAS 116249-66-2 (free form)
Link

Benanomicin B

Iturin A-2, Antifungal Antitumor

DatasheetThis may not be the latest data sheet.


  • Product Code: 15171
  • Supplier: IMC
  • Size: 1mg
  • Price: $500

Description M.W.: 1,043.190 Purity : >90％ (HPLC) Molecular Formula : C48H74N12O14 Solubility : Soluble in MeOH, DMSO, and DMF Insoluble in H2O. Iturin A-2 is a cyclic polypeptide with antifungal activity. It was reported that the bioactive compound showed suppression of damping-off of tomato (a seeding disease) and cytotoxicity to human breast cancer cell line BT-474. Pharmacophore mapping studies suggested that the angiotensin-converting enzyme 2 (ACE2) as one of the potential targets of iturin A-2. This finding indicates that these lipopeptides may bind to SARS-CoV-2 nsp12 (RNA-dependent RNA polymerase) efficiently.
Storage -20°C CAS 83785-07-3
Link

Iturin A-2 [CAS: 83785-07-3]

Plipastatin A1, Phospholipase Inhibitor

DatasheetThis may not be the latest data sheet.


  • Product Code: 15170
  • Supplier: IMC
  • Size: 1mg
  • Price: $500

Description M.W.: 1463.736　Purity : >90 % (HPLC) Solubility : Soluble in H2O, MeOH and DMSO, Insoluble in acetone, ethyl acetate Plipastatin A1, a member of lipopeptide containing a C16 3-hydroxyl fatty acid and 11 amino acids,　was isolated as an inhibitor of phospholipase A2 from the fermentation broth of Bacillus cereus BMG302-fF67. ) It showed the inhibitory activity on phospholipase A2 (IC50: 2.9 μM), C (IC50: 1.3 μM) and D (IC50: 1.4 μM).
Storage -20°C CAS 103651-09-8
Link

Plipastatin A1 [CAS: 103651-09-8]


Back to Product Lineup


Inhibition of Protein Synthesis in Bacteria

[Date : October 09 2025 00:07]

Detail Product Name Product Code Supplier Size Price
Althiomycin, Bacterial Protein Synthesis Inhibitor, Antibacterial (Gram-Positive & Negative)
DatasheetThis may not be the latest data sheet. 		14660 IMCInstitute of Microbial Chemistry 1 mg $500

Description M.W.: 439.461 Purity : >98% (HPLC) Molecular Formula : C16H17N5O6S2 Solubility : Soluble in 2-ethoxy ethanol (ethyl cellosolve), pyridine, and DMSO. Poorly soluble in MeOH, EtOAc, and acetone. Insoluble in H2O. Althiomycin is a sulfur containing peptide antibiotic obtained from Streptomyces. This natural compound is active against both gram-positive and-negative bacteria and inhibits protein synthesis in both intact cells and cell-free system of E. coli.
Storage -20°C CAS 12656-40-5
Link

Althiomycin

Minosaminomicin, Bacterial Protein Synthesis Inhibitor
DatasheetThis may not be the latest data sheet. 		02872 IMCInstitute of Microbial Chemistry 1 mg $500

Description M.W.: 618.689 Purity : >98％ (HPLC) Molecular Formula : C25H46N8O10 Solubility : Soluble in MeOH, DMSO, and H2O, Insoluble in Hexane. Minosaminomycin inhibits phage f2 RNA-directed protein synthesis in a cell-free system of Escherichia coli by 50% at 0.2 µM. It was also reported that minimum inhibitory concentrations of the bioactive compound were determined as 1.56 µg/ml for Mycobacterium smegmatis ATCC 607 and 6.25 µg/ml for Mycobacterium phlei, respectively.
Storage -20°C CAS 51746-09-9
Link

Minosaminomycin

Negamycin (Hydrochloride), Antibacterial (Gram-Positive & Negative), Bacterial Protein Synthesis Inhibitor
DatasheetThis may not be the latest data sheet. 		14662 IMCInstitute of Microbial Chemistry 5 mg $500

Description M.W.: 284.741（mono HCl salt） Purity : >80% (qNMR) Molecular Formula : C9H20N4O4･HCl Solubility : Soluble in DMSO, Insoluble in hexane Negamycin exhibits anti-bacterial activity against gram-positive and gram-negative bacteria including multidrug-resistant Pseudomonas and cause inhibition of protein synthesis by interacting helix 34 (h34) element of 16S rRNA. This product is supplied as HCl salt.
Storage -20°C CAS 33404-78-3 (salt free form)
Link

Negamycin (hydrochloride)

[Date : October 09 2025 00:07]

Althiomycin, Bacterial Protein Synthesis Inhibitor, Antibacterial (Gram-Positive & Negative)

DatasheetThis may not be the latest data sheet.


  • Product Code: 14660
  • Supplier: IMC
  • Size: 1mg
  • Price: $500

Description M.W.: 439.461 Purity : >98% (HPLC) Molecular Formula : C16H17N5O6S2 Solubility : Soluble in 2-ethoxy ethanol (ethyl cellosolve), pyridine, and DMSO. Poorly soluble in MeOH, EtOAc, and acetone. Insoluble in H2O. Althiomycin is a sulfur containing peptide antibiotic obtained from Streptomyces. This natural compound is active against both gram-positive and-negative bacteria and inhibits protein synthesis in both intact cells and cell-free system of E. coli.
Storage -20°C CAS 12656-40-5
Link

Althiomycin

Minosaminomicin, Bacterial Protein Synthesis Inhibitor

DatasheetThis may not be the latest data sheet.


  • Product Code: 02872
  • Supplier: IMC
  • Size: 1mg
  • Price: $500

Description M.W.: 618.689 Purity : >98％ (HPLC) Molecular Formula : C25H46N8O10 Solubility : Soluble in MeOH, DMSO, and H2O, Insoluble in Hexane. Minosaminomycin inhibits phage f2 RNA-directed protein synthesis in a cell-free system of Escherichia coli by 50% at 0.2 µM. It was also reported that minimum inhibitory concentrations of the bioactive compound were determined as 1.56 µg/ml for Mycobacterium smegmatis ATCC 607 and 6.25 µg/ml for Mycobacterium phlei, respectively.
Storage -20°C CAS 51746-09-9
Link

Minosaminomycin

Negamycin (Hydrochloride), Antibacterial (Gram-Positive & Negative), Bacterial Protein Synthesis Inhibitor

DatasheetThis may not be the latest data sheet.


  • Product Code: 14662
  • Supplier: IMC
  • Size: 5mg
  • Price: $500

Description M.W.: 284.741（mono HCl salt） Purity : >80% (qNMR) Molecular Formula : C9H20N4O4･HCl Solubility : Soluble in DMSO, Insoluble in hexane Negamycin exhibits anti-bacterial activity against gram-positive and gram-negative bacteria including multidrug-resistant Pseudomonas and cause inhibition of protein synthesis by interacting helix 34 (h34) element of 16S rRNA. This product is supplied as HCl salt.
Storage -20°C CAS 33404-78-3 (salt free form)
Link

Negamycin (hydrochloride)


Back to Product Lineup


Pneumocystis Pneumonia Suppression

[Date : October 09 2025 00:07]

Detail Product Name Product Code Supplier Size Price
Benanomicin A, Antifungal via Binding to Mannan
DatasheetThis may not be the latest data sheet. 		02966 IMCInstitute of Microbial Chemistry 1 mg $500

Description M.W.: 827.74 Purity : > 90％ (HPLC) Molecular Formula : C39H41NO19 Solubility : Soluble in DMSO and DMF, Poorly soluble in MeOH and CHCl3 Insoluble in H2O, Antimicrobial activity (MIC) : Cryptococcus neoformans F-10 0.6~1.25 μg/ml, Cryptococcus laurenti 0.63 μg/ml, Rhodotorula rubra 0.63 μg/ml, Tricosporon cutaneum 1.25~5 μg/ml. Benanomicin A is isolated from Actinomadura sp. MH193-16F4. This compound exhibits excellent therapeutic efficacy against in a Pneumocystis carinii-infected mouse model by intraperitoneal administration at 10mg/kg/day. In addition, this compound also has antimycotic activities via binding to mannan in the cell walls of fungi. It is recently reported that this compound has been utilized to prepare mannan cell walls by the lectin-like functionality of it.
Storage -20°C CAS 116249-65-1
Link

Benanomicin A

[Date : October 09 2025 00:07]

Benanomicin A, Antifungal via Binding to Mannan

DatasheetThis may not be the latest data sheet.


  • Product Code: 02966
  • Supplier: IMC
  • Size: 1mg
  • Price: $500

Description M.W.: 827.74 Purity : > 90％ (HPLC) Molecular Formula : C39H41NO19 Solubility : Soluble in DMSO and DMF, Poorly soluble in MeOH and CHCl3 Insoluble in H2O, Antimicrobial activity (MIC) : Cryptococcus neoformans F-10 0.6~1.25 μg/ml, Cryptococcus laurenti 0.63 μg/ml, Rhodotorula rubra 0.63 μg/ml, Tricosporon cutaneum 1.25~5 μg/ml. Benanomicin A is isolated from Actinomadura sp. MH193-16F4. This compound exhibits excellent therapeutic efficacy against in a Pneumocystis carinii-infected mouse model by intraperitoneal administration at 10mg/kg/day. In addition, this compound also has antimycotic activities via binding to mannan in the cell walls of fungi. It is recently reported that this compound has been utilized to prepare mannan cell walls by the lectin-like functionality of it.
Storage -20°C CAS 116249-65-1
Link

Benanomicin A


Back to Product Lineup


Anti-HIV-Ⅰ

[Date : October 09 2025 00:07]

Detail Product Name Product Code Supplier Size Price
Benanomicin A, Antifungal via Binding to Mannan
DatasheetThis may not be the latest data sheet. 		02966 IMCInstitute of Microbial Chemistry 1 mg $500

Description M.W.: 827.74 Purity : > 90％ (HPLC) Molecular Formula : C39H41NO19 Solubility : Soluble in DMSO and DMF, Poorly soluble in MeOH and CHCl3 Insoluble in H2O, Antimicrobial activity (MIC) : Cryptococcus neoformans F-10 0.6~1.25 μg/ml, Cryptococcus laurenti 0.63 μg/ml, Rhodotorula rubra 0.63 μg/ml, Tricosporon cutaneum 1.25~5 μg/ml. Benanomicin A is isolated from Actinomadura sp. MH193-16F4. This compound exhibits excellent therapeutic efficacy against in a Pneumocystis carinii-infected mouse model by intraperitoneal administration at 10mg/kg/day. In addition, this compound also has antimycotic activities via binding to mannan in the cell walls of fungi. It is recently reported that this compound has been utilized to prepare mannan cell walls by the lectin-like functionality of it.
Storage -20°C CAS 116249-65-1
Link

Benanomicin A

Benanomicin B, Antifungal
DatasheetThis may not be the latest data sheet. 		02968 IMCInstitute of Microbial Chemistry 1 mg $500

Description M.W.: 826.761 Purity : > 90％ (HPLC) Molecular Formula : C39H42N2O18 Solubility : Soluble in DMSO, Insoluble in H2O, Antimicrobial activity (MIC) : Cryptococcus neoformans F-10 1.56 μg/ml, Candida pseudotropicalis F-2 6.25 μg/ml, Candida kusei F-5 6.25 μg/ml, Candida sp. Yu-1200 6.25 μg/ml, Saccharomyces cerevisiae F-7 6.25 μg/ml. Benanomicin B is an antibiotic isolated from the culture fluid of Actinomadura sp. MH193-16F4. This compound prevented HIV-1 infection to human T-cells and syncytium formation. In addition, the natural compound is also reported antifungal and antibacterial activities against Candida, Cryptococcus and Saccharomyces, etc.
Storage -20°C CAS 116249-66-2 (free form)
Link

Benanomicin B

[Date : October 09 2025 00:07]

Benanomicin A, Antifungal via Binding to Mannan

DatasheetThis may not be the latest data sheet.


  • Product Code: 02966
  • Supplier: IMC
  • Size: 1mg
  • Price: $500

Description M.W.: 827.74 Purity : > 90％ (HPLC) Molecular Formula : C39H41NO19 Solubility : Soluble in DMSO and DMF, Poorly soluble in MeOH and CHCl3 Insoluble in H2O, Antimicrobial activity (MIC) : Cryptococcus neoformans F-10 0.6~1.25 μg/ml, Cryptococcus laurenti 0.63 μg/ml, Rhodotorula rubra 0.63 μg/ml, Tricosporon cutaneum 1.25~5 μg/ml. Benanomicin A is isolated from Actinomadura sp. MH193-16F4. This compound exhibits excellent therapeutic efficacy against in a Pneumocystis carinii-infected mouse model by intraperitoneal administration at 10mg/kg/day. In addition, this compound also has antimycotic activities via binding to mannan in the cell walls of fungi. It is recently reported that this compound has been utilized to prepare mannan cell walls by the lectin-like functionality of it.
Storage -20°C CAS 116249-65-1
Link

Benanomicin A

Benanomicin B, Antifungal

DatasheetThis may not be the latest data sheet.


  • Product Code: 02968
  • Supplier: IMC
  • Size: 1mg
  • Price: $500

Description M.W.: 826.761 Purity : > 90％ (HPLC) Molecular Formula : C39H42N2O18 Solubility : Soluble in DMSO, Insoluble in H2O, Antimicrobial activity (MIC) : Cryptococcus neoformans F-10 1.56 μg/ml, Candida pseudotropicalis F-2 6.25 μg/ml, Candida kusei F-5 6.25 μg/ml, Candida sp. Yu-1200 6.25 μg/ml, Saccharomyces cerevisiae F-7 6.25 μg/ml. Benanomicin B is an antibiotic isolated from the culture fluid of Actinomadura sp. MH193-16F4. This compound prevented HIV-1 infection to human T-cells and syncytium formation. In addition, the natural compound is also reported antifungal and antibacterial activities against Candida, Cryptococcus and Saccharomyces, etc.
Storage -20°C CAS 116249-66-2 (free form)
Link

Benanomicin B


Back to Product Lineup


Immunoregulation

[Date : October 09 2025 00:07]

Detail Product Name Product Code Supplier Size Price
Forphenicinol, Immunomodifier
DatasheetThis may not be the latest data sheet. 		09637 IMCInstitute of Microbial Chemistry 1 mg $500

Description M.W.: 197.190 Purity : >98% (HPLC) Molecular Formula : C9H11NO4 Solubility : Soluble in MeOH, DMSO, and H2O Insoluble in hexane. Forphenicinol is a synthesized derivative of forphenicine, the inhibitor of alkaline phosphatase produced by Streptomyces. The compound does not have inhibitory activity to alkaline phosphatase. It exhibits biological activities such as enhanced delayed hypersensitivity, enhanced macrophage phagocytosis, antitumor effects on transplanted tumors, and enhanced resistance to Pseudomonas aeruginosa infection in mice, while being extremely low toxicity.
Storage -20°C CAS 71522-58-2
Link

Forphenicinol

[Date : October 09 2025 00:07]

Forphenicinol, Immunomodifier

DatasheetThis may not be the latest data sheet.


  • Product Code: 09637
  • Supplier: IMC
  • Size: 1mg
  • Price: $500

Description M.W.: 197.190 Purity : >98% (HPLC) Molecular Formula : C9H11NO4 Solubility : Soluble in MeOH, DMSO, and H2O Insoluble in hexane. Forphenicinol is a synthesized derivative of forphenicine, the inhibitor of alkaline phosphatase produced by Streptomyces. The compound does not have inhibitory activity to alkaline phosphatase. It exhibits biological activities such as enhanced delayed hypersensitivity, enhanced macrophage phagocytosis, antitumor effects on transplanted tumors, and enhanced resistance to Pseudomonas aeruginosa infection in mice, while being extremely low toxicity.
Storage -20°C CAS 71522-58-2
Link

Forphenicinol


Back to Product Lineup


Lectin-like Function

[Date : October 09 2025 00:07]

Detail Product Name Product Code Supplier Size Price
Benanomicin A, Antifungal via Binding to Mannan
DatasheetThis may not be the latest data sheet. 		02966 IMCInstitute of Microbial Chemistry 1 mg $500

Description M.W.: 827.74 Purity : > 90％ (HPLC) Molecular Formula : C39H41NO19 Solubility : Soluble in DMSO and DMF, Poorly soluble in MeOH and CHCl3 Insoluble in H2O, Antimicrobial activity (MIC) : Cryptococcus neoformans F-10 0.6~1.25 μg/ml, Cryptococcus laurenti 0.63 μg/ml, Rhodotorula rubra 0.63 μg/ml, Tricosporon cutaneum 1.25~5 μg/ml. Benanomicin A is isolated from Actinomadura sp. MH193-16F4. This compound exhibits excellent therapeutic efficacy against in a Pneumocystis carinii-infected mouse model by intraperitoneal administration at 10mg/kg/day. In addition, this compound also has antimycotic activities via binding to mannan in the cell walls of fungi. It is recently reported that this compound has been utilized to prepare mannan cell walls by the lectin-like functionality of it.
Storage -20°C CAS 116249-65-1
Link

Benanomicin A

[Date : October 09 2025 00:07]

Benanomicin A, Antifungal via Binding to Mannan

DatasheetThis may not be the latest data sheet.


  • Product Code: 02966
  • Supplier: IMC
  • Size: 1mg
  • Price: $500

Description M.W.: 827.74 Purity : > 90％ (HPLC) Molecular Formula : C39H41NO19 Solubility : Soluble in DMSO and DMF, Poorly soluble in MeOH and CHCl3 Insoluble in H2O, Antimicrobial activity (MIC) : Cryptococcus neoformans F-10 0.6~1.25 μg/ml, Cryptococcus laurenti 0.63 μg/ml, Rhodotorula rubra 0.63 μg/ml, Tricosporon cutaneum 1.25~5 μg/ml. Benanomicin A is isolated from Actinomadura sp. MH193-16F4. This compound exhibits excellent therapeutic efficacy against in a Pneumocystis carinii-infected mouse model by intraperitoneal administration at 10mg/kg/day. In addition, this compound also has antimycotic activities via binding to mannan in the cell walls of fungi. It is recently reported that this compound has been utilized to prepare mannan cell walls by the lectin-like functionality of it.
Storage -20°C CAS 116249-65-1
Link

Benanomicin A


Back to Product Lineup


Inhibition of Aflatoxin Production

[Date : October 09 2025 00:07]

Detail Product Name Product Code Supplier Size Price
Dioctatin A (Hydrochloride), Human Dipeptidyl Aminopeptidase II Inhibitor, Aflatoxin Production Inhibitor
DatasheetThis may not be the latest data sheet. 		14700 IMCInstitute of Microbial Chemistry 1 mg $500

Description M.W.: 434.018 (hydrochloride salt form) Purity : >95% (HPLC) Molecular Formula : C21H39N3O4･HCl Solubility : Soluble in acidic DMSO, acidic MeOH, and acidic H2O Dioctatin A is a selective inhibitor of dipeptidyl aminopeptidase II (DPP2) in pancreas of rat. It was found that this bioactive compound strongly inhibited aflatoxin production by Aspergillus parasiticus.
Storage -20°C CAS 138146-67-5 (salt free form)
Link

Dioctatin A (Hydrochloride)

[Date : October 09 2025 00:07]

Dioctatin A (Hydrochloride), Human Dipeptidyl Aminopeptidase II Inhibitor, Aflatoxin Production Inhibitor

DatasheetThis may not be the latest data sheet.


  • Product Code: 14700
  • Supplier: IMC
  • Size: 1mg
  • Price: $500

Description M.W.: 434.018 (hydrochloride salt form) Purity : >95% (HPLC) Molecular Formula : C21H39N3O4･HCl Solubility : Soluble in acidic DMSO, acidic MeOH, and acidic H2O Dioctatin A is a selective inhibitor of dipeptidyl aminopeptidase II (DPP2) in pancreas of rat. It was found that this bioactive compound strongly inhibited aflatoxin production by Aspergillus parasiticus.
Storage -20°C CAS 138146-67-5 (salt free form)
Link

Dioctatin A (Hydrochloride)


Back to Product Lineup


Induced Systemic Resistance

[Date : October 09 2025 00:07]

Detail Product Name Product Code Supplier Size Price
Iturin A-2, Antifungal Antitumor
DatasheetThis may not be the latest data sheet. 		15171 IMCInstitute of Microbial Chemistry 1 mg $500

Description M.W.: 1,043.190 Purity : >90％ (HPLC) Molecular Formula : C48H74N12O14 Solubility : Soluble in MeOH, DMSO, and DMF Insoluble in H2O. Iturin A-2 is a cyclic polypeptide with antifungal activity. It was reported that the bioactive compound showed suppression of damping-off of tomato (a seeding disease) and cytotoxicity to human breast cancer cell line BT-474. Pharmacophore mapping studies suggested that the angiotensin-converting enzyme 2 (ACE2) as one of the potential targets of iturin A-2. This finding indicates that these lipopeptides may bind to SARS-CoV-2 nsp12 (RNA-dependent RNA polymerase) efficiently.
Storage -20°C CAS 83785-07-3
Link

Iturin A-2 [CAS: 83785-07-3]

Plipastatin A1, Phospholipase Inhibitor
DatasheetThis may not be the latest data sheet. 		15170 IMCInstitute of Microbial Chemistry 1 mg $500

Description M.W.: 1463.736　Purity : >90 % (HPLC) Solubility : Soluble in H2O, MeOH and DMSO, Insoluble in acetone, ethyl acetate Plipastatin A1, a member of lipopeptide containing a C16 3-hydroxyl fatty acid and 11 amino acids,　was isolated as an inhibitor of phospholipase A2 from the fermentation broth of Bacillus cereus BMG302-fF67. ) It showed the inhibitory activity on phospholipase A2 (IC50: 2.9 μM), C (IC50: 1.3 μM) and D (IC50: 1.4 μM).
Storage -20°C CAS 103651-09-8
Link

Plipastatin A1 [CAS: 103651-09-8]

[Date : October 09 2025 00:07]

Iturin A-2, Antifungal Antitumor

DatasheetThis may not be the latest data sheet.


  • Product Code: 15171
  • Supplier: IMC
  • Size: 1mg
  • Price: $500

Description M.W.: 1,043.190 Purity : >90％ (HPLC) Molecular Formula : C48H74N12O14 Solubility : Soluble in MeOH, DMSO, and DMF Insoluble in H2O. Iturin A-2 is a cyclic polypeptide with antifungal activity. It was reported that the bioactive compound showed suppression of damping-off of tomato (a seeding disease) and cytotoxicity to human breast cancer cell line BT-474. Pharmacophore mapping studies suggested that the angiotensin-converting enzyme 2 (ACE2) as one of the potential targets of iturin A-2. This finding indicates that these lipopeptides may bind to SARS-CoV-2 nsp12 (RNA-dependent RNA polymerase) efficiently.
Storage -20°C CAS 83785-07-3
Link

Iturin A-2 [CAS: 83785-07-3]

Plipastatin A1, Phospholipase Inhibitor

DatasheetThis may not be the latest data sheet.


  • Product Code: 15170
  • Supplier: IMC
  • Size: 1mg
  • Price: $500

Description M.W.: 1463.736　Purity : >90 % (HPLC) Solubility : Soluble in H2O, MeOH and DMSO, Insoluble in acetone, ethyl acetate Plipastatin A1, a member of lipopeptide containing a C16 3-hydroxyl fatty acid and 11 amino acids,　was isolated as an inhibitor of phospholipase A2 from the fermentation broth of Bacillus cereus BMG302-fF67. ) It showed the inhibitory activity on phospholipase A2 (IC50: 2.9 μM), C (IC50: 1.3 μM) and D (IC50: 1.4 μM).
Storage -20°C CAS 103651-09-8
Link

Plipastatin A1 [CAS: 103651-09-8]


Back to Product Lineup

Go back to index

CONTACT

export@funakoshi.co.jp

  • ※Prices on our website are for your reference only. Please inquire your distributor for your prices.
  • ※Please note that Product Information or Price may change without notice.