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HOME> Products> Natural and Chemical compound> Benastatin A

Glutathione S-Transferase (GST) Inhibitor Benastatin A

Date：July 03 2020Web Page No：520041

Benastatin A is isolated from the culture broth of Streptomyces sp. MI384-DF12 as an inhibitor of glutathione S-transferase (GST).^1,2) It has antibacterial activity against gram-positive bacteria including methicillin-resistant Staphylococcus aureus (MRSA).¹⁾

Specification
Application Note
Reference

Specification

CAS#	138968-85-1
Molecular Formula	C₃₀H₂₈O₇
Molecular Weight	500.547
Source	Streptomyces sp. MI384-DF12
Purity	> 95% (HPLC)
Solubility	Soluble in DMSO. Poorly soluble in MeOH, CHCl₃. Insoluble in H₂O.

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Application Note

The inhibition of benastatin A against GST is competitive with 3,4-dichloronitrobenzene (Ki: 5.0 × 10^-6 M), and noncompetitive with glutathione (Ki: 3.5×10^-6 M).
Benastatin A has activity against gram-positive bacteria including methicillin-resistant Staphylococcus aureus (MRSA).¹⁾

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Reference

Aoyagi T. et al. J. Antibiot., 45(9), 1385～1390 (1992).
Aoyagi T. et al. J. Antibiot., 45(9), 1391～1396 (1992).

[Date : February 15 2024 12:37]

Detail Product Name Product Code Supplier Size Price

Benastatin A,Glutathione S-Transferase (GST) Inhibitor
DatasheetThis may not be the latest data sheet. 00379 IMCInstitute of Microbial Chemistry 1 mg $500

Contact

Description
Storage	-20°C	CAS	138968-85-1
Link	Bioactive Compounds

[Date : February 15 2024 12:37]

Benastatin A,Glutathione S-Transferase (GST) Inhibitor

DatasheetThis may not be the latest data sheet.

Product Code: 00379
Supplier: IMC
Size: 1mg
Price: $500

Description
Storage	-20°C	CAS	138968-85-1
Link	Bioactive Compounds

Contact

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