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Tumor Cell Migration Inhibitor, Antitumor Migrastatin

Date:January 20 2020Web Page No:81424

Migrastatin inhibits tumor cell migration, thus offering a possible way to inhibit metastasis.

Migrastatin stop tumor cell micration

Application Notes

  • Migrastatin inhibits cell migration of human esophageal cancer (EC17) & mouse melanoma (B16) cells 1).
  • It was found to inhibit anchorage-independent growth of human small cell lung carcinoma (Ms-1) cells 2).

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Specifications

  • Code No. : 10708
  • CAS# : 314245-65-3
  • Molecular Formula : C27H39NO7
  • Molecular Weight : 489.609
  • Source : Streptomyces sp. MK929-43F1
  • Appearance : White powder
  • Purity : > 95% (HPLC)
  • Storage : -20℃
  • Solubility : Soluble in MeOH, DMSO, DMF. Insoluble in H2O.

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Reference

  1. Migrastatin, a New Inhibitor of Tumor Cell Migration from Streptomyces sp. MK929-43F1. Taxonomy, Fermentation, Isolation and Biological Activities.
    Nakae K, Yoshimoto Y, Sawa T, Homma Y, Hamada M, Takeuchi T, Imoto M.
    J. Antibiotics, 2000, 53, 1130-1136.
  2. Migrastatin, a novel 14-membered ring macrolide, inhibits anchorage-independent growth of human small cell lung carcinoma Ms-1 cells.
    Takemoto Y, Nakae K, Kawatani M, Takahashi Y, Naganawa H, Imoto M.
    J. Antibiotics, 2001, 54, 1104-1107.

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Product Information

IMC banner

[Date : August 13 2022 00:32]

Detail Product Name Product Code Supplier Size Price
Migrastatin,Tumor Cell Migration Inhibitor,Antitumor
DatasheetThis may not be the latest data sheet.
10708 IMCInstitute of Microbial Chemistry 1 mg $500

Description
Storage -20°C CAS 314245-65-3
Link

Bioactive Compounds

[Date : August 13 2022 00:32]

Migrastatin,Tumor Cell Migration Inhibitor,Antitumor


  • Product Code: 10708
  • Supplier: IMC
  • Size: 1mg
  • Price: $500

Description
Storage -20°C CAS 314245-65-3
Link

Bioactive Compounds

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