HOME> Products> Natural and Chemical compound> Dopastin

Natural Product with Hypotensive Effect Dopastin

Date:July 03 2020Web Page No:520043

Dopastin is a natural product isolated and purified from Pseudomonas No. BAC-125.

Dopastin structure

Specification

CAS#37134-80-8
Molecular FormulaC9H17N3O3
Molecular Weight215.253
Purity> 90%
SolubilitySoluble in MeOH, Butanol, Acetone, CHCl3 and Alkaline water
Insoluble in water, Ethyl acetate, Ether and Hexane

Go back to index

Application Note

  • Dopastin is a potent inhibitor of dopamine β-hydroxylase of beef adrenals (IC50= 4.7 × 10-6M).1)
  • Dopastin shows a significant hypotensive effect to spontaneously hypertensive rats.2)
  • Dopastin shows a phytotoxicity to barley germination.2)
  • Dopastin has low toxicity (oral LD50:750 mg/kg, i.p. LD50:460 mg/kg in mice), and the intravenous injection of 250 mg/kg killed no mice.1)

Go back to index

Reference

  1. Iinuma H. et al. J. Antibiot., 25(8), 497-500(1972).
  2. Iinuma H. et al. Agric. Biol. Chem., 38(11), 2107-2111(1974).

  3. Structure and synthesis method:
  4. Iinuma H. et al. Agric. Biol. Chem., 38(11), 2099-2105(1974).

IMC banner

[Date : June 25 2024 00:08]

Detail Product Name Product Code Supplier Size Price
Dopastin,Dopamine β-Hydroxylase Inhibitor
DatasheetThis may not be the latest data sheet.
00381 IMCInstitute of Microbial Chemistry 1 mg $500

Description
Storage -20°C CAS 37134-80-8
Link

Bioactive Compounds

[Date : June 25 2024 00:08]

Dopastin,Dopamine β-Hydroxylase Inhibitor


  • Product Code: 00381
  • Supplier: IMC
  • Size: 1mg
  • Price: $500

Description
Storage -20°C CAS 37134-80-8
Link

Bioactive Compounds

Go back to index

CONTACT

export@funakoshi.co.jp

  • Prices are for USA / Canada customers. Prices do not include shipping and handling charges, VAT, import tariffs and service charge etc.
  • Please note that Product Information or Price may change without notice.