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Trehalase Resistant Lentztrehalose A

Date:April 14 2022Web Page No:95023

Lentztrehalose A: Trehalase Resistant

Lentztrehalose A

Specification

CAS#1609356-99-1
Molecular FormulaC17H32O13
Molecular Weight444.430
SourceLentzea sp. ML457-mF8
Purity>80% (qNMR)
Long Term Storageat -20˚C
SolubilitySoluble in MeOH, DMSO, H2O
Insoluble in Hexane

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Application Notes

  • Lentztrehalose A is a biologically stable analog of trehalose, isolated from the soilid-state culture of Lentzea sp. ML457-mF8.1-3)
  • Lentztrehalose A is resistant to porcine kidney trehalase and various microbes which degrades trehalose3) and it shows tolehalose like bioactivities, such as bone reinforcement and anti-obesity effect in a postmenopausal mouse model.1)
  • Lentztrehalose A has antitumor activity, which trehalose does not show, in mice bearing S-180 sarcoma and Ehrlich carcinoma cells at 12.5-50 mg/kg per day without apparent toxicity tomammalian cells.1)

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References

  1. Structure and biological properties of lentztrehalose: a novel trehalose analog. Wada S, et al., J. Antibiot., 2014 67 (4) 319-322.
  2. Synthesis and determination of absolute configuration of lentztrehalose A. Zhang M, et al., Chem. Pharm. Bull., 2015 63 (11) 961-966.
  3. Stability and bioavailability of lentztrehaloses A, B, and C as replacements for trehalose. Wada S, et al., J. Agric. Food Chem., 2016 64 (38) 7121-7126.

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[Date : June 20 2024 00:07]

Detail Product Name Product Code Supplier Size Price
Lentztrehalose A,Trehalase Resistant
DatasheetThis may not be the latest data sheet.
14678 IMCInstitute of Microbial Chemistry 25 mg $500

Description Biologically stable analogue of trehalose
Storage -20°C CAS 1609356-99-1
Link

Bioactive Compounds
Lentztrehalose A and its analogues B, C

[Date : June 20 2024 00:07]

Lentztrehalose A,Trehalase Resistant


  • Product Code: 14678
  • Supplier: IMC
  • Size: 25mg
  • Price: $500

Description Biologically stable analogue of trehalose
Storage -20°C CAS 1609356-99-1
Link

Bioactive Compounds
Lentztrehalose A and its analogues B, C


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