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Lentztrehalose A
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Lentztrehalose A
Trehalase Resistant Lentztrehalose A
Date：April 14 2022Web Page No：95023
Lentztrehalose A: Trehalase Resistant
Specification
| CAS# | 1609356-99-1 |
|---|---|
| Molecular Formula | C17H32O13 |
| Molecular Weight | 444.430 |
| Source | Lentzea sp. ML457-mF8 |
| Purity | >80% (qNMR) |
| Long Term Storage | at -20˚C |
| Solubility | Soluble in MeOH, DMSO, H2O Insoluble in Hexane |
Application Notes
- Lentztrehalose A is a biologically stable analog of trehalose, isolated from the soilid-state culture of Lentzea sp. ML457-mF8.1-3)
- Lentztrehalose A is resistant to porcine kidney trehalase and various microbes which degrades trehalose3) and it shows tolehalose like bioactivities, such as bone reinforcement and anti-obesity effect in a postmenopausal mouse model.1)
- Lentztrehalose A has antitumor activity, which trehalose does not show, in mice bearing S-180 sarcoma and Ehrlich carcinoma cells at 12.5-50 mg/kg per day without apparent toxicity tomammalian cells.1)
References
- Structure and biological properties of lentztrehalose: a novel trehalose analog. Wada S, et al., J. Antibiot., 2014 67 (4) 319-322.
- Synthesis and determination of absolute configuration of lentztrehalose A. Zhang M, et al., Chem. Pharm. Bull., 2015 63 (11) 961-966.
- Stability and bioavailability of lentztrehaloses A, B, and C as replacements for trehalose. Wada S, et al., J. Agric. Food Chem., 2016 64 (38) 7121-7126.
[Date : February 15 2024 12:37]
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Lentztrehalose A,Trehalase Resistant DatasheetThis may not be the latest data sheet. |
14678 | IMCInstitute of Microbial Chemistry | 25 mg | $500 | |||||||||||||||||||||||||||||||
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[Date : February 15 2024 12:37]
Lentztrehalose A,Trehalase Resistant
DatasheetThis may not be the latest data sheet.
- Product Code: 14678
- Supplier: IMC
- Size: 25mg
- Price: $500
| Description |
Biologically stable analogue of trehalose |
||
|---|---|---|---|
| Storage | -20°C | CAS | 1609356-99-1 |
| Link | |||
CONTACT
export@funakoshi.co.jp
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