Trehalase Resistant Lentztrehalose A

• Specification
• Application Notes
• References

Specification

CAS#	1609356-99-1
Molecular Formula	C17H32O13
Molecular Weight	444.430
Source	Lentzea sp. ML457-mF8
Purity	>80% (qNMR)
Long Term Storage	at -20˚C
Solubility	Soluble in MeOH, DMSO, H2O Insoluble in Hexane

Go back to index

Application Notes

• Lentztrehalose A is a biologically stable analog of trehalose, isolated from the soilid-state culture of Lentzea sp. ML457-mF8.^1-3)
• Lentztrehalose A is resistant to porcine kidney trehalase and various microbes which degrades trehalose³⁾ and it shows tolehalose like bioactivities, such as bone reinforcement and anti-obesity effect in a postmenopausal mouse model.¹⁾
• Lentztrehalose A has antitumor activity, which trehalose does not show, in mice bearing S-180 sarcoma and Ehrlich carcinoma cells at 12.5-50 mg/kg per day without apparent toxicity tomammalian cells.¹⁾

Go back to index

References

Go back to index