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Glutathione S-Transferase (GST) Inhibitor Benastatin B

Date:July 03 2020Web Page No:520051

Benastatin B is isolated from the culture broth of Streptomyces sp. MI384-DF12 as an inhibitor of glutathione S-transferase (GST).1,2)

Benastatin B

Specification

CAS#138968-86-2
Molecular FormulaC30H30O7
Molecular Weight502.563
SourceStreptomyces sp. MI384-DF12
Purity> 95% (HPLC)
SolubilitySoluble in DMSO. Poorly soluble in MeOH, Acetone, EtOAc.
Insoluble in H2O

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Application Note

  • The inhibition of benastatin B against GST is competitive with 3,4-dichloronitrobenzene (Ki:3.7×10-6 M), and noncompetitive with glutathione (Ki:4.2×10-6 M).
  • Benastatin B has activity against Gram-positive bacteria including methicillin-resistant Staphylococcus aureus (MRSA).1)

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Reference

  1. Aoyagi T. et al. J. Antibiot., 45(9), 1385~1390 (1992).
  2. Aoyagi T. et al. J. Antibiot., 45(9), 1391~1396 (1992).

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[Date : February 15 2024 12:37]

Detail Product Name Product Code Supplier Size Price
Benastatin B,Glutathione S-Transferase (GST) Inhibitor
DatasheetThis may not be the latest data sheet.
14653 IMCInstitute of Microbial Chemistry 1 mg $500

Description
Storage -20°C CAS 138968-86-2
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Bioactive Compounds

[Date : February 15 2024 12:37]

Benastatin B,Glutathione S-Transferase (GST) Inhibitor


  • Product Code: 14653
  • Supplier: IMC
  • Size: 1mg
  • Price: $500

Description
Storage -20°C CAS 138968-86-2
Link

Bioactive Compounds

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