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HOME> Products> Natural and Chemical compound> Enzyme inhibitor> Benastatin B

Glutathione S-Transferase (GST) Inhibitor Benastatin B

Date：July 03 2020Web Page No：520051

Benastatin B is isolated from the culture broth of Streptomyces sp. MI384-DF12 as an inhibitor of glutathione S-transferase (GST).^1,2)

Specification
Application Note
Reference

Specification

CAS#	138968-86-2
Molecular Formula	C₃₀H₃₀O₇
Molecular Weight	502.563
Source	Streptomyces sp. MI384-DF12
Purity	> 95% (HPLC)
Solubility	Soluble in DMSO. Poorly soluble in MeOH, Acetone, EtOAc. Insoluble in H₂O

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Application Note

The inhibition of benastatin B against GST is competitive with 3,4-dichloronitrobenzene (Ki:3.7×10^-6 M), and noncompetitive with glutathione (Ki:4.2×10^-6 M).
Benastatin B has activity against Gram-positive bacteria including methicillin-resistant Staphylococcus aureus (MRSA).¹⁾

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Reference

Aoyagi T. et al. J. Antibiot., 45(9), 1385～1390 (1992).
Aoyagi T. et al. J. Antibiot., 45(9), 1391～1396 (1992).

[Date : May 16 2025 00:07]

Detail Product Name Product Code Supplier Size Price

Benastatin B, Glutathione S-Transferase (GST) Inhibitor
DatasheetThis may not be the latest data sheet. 14653 IMCInstitute of Microbial Chemistry 1 mg $500

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Description	M.W.: 502.563 Purity : > 95％ (HPLC) Molecular Formula : C30H30O7 Solubility : Soluble in DMSO, Poorly soluble in MeOH, Acetone, EtOAc, Insoluble in H2O. Benastatin B exhibited competitive inhibitory activity with 3,4-dichloronitrobenzene (Ki:3.7×10^-6 M), and noncompetitive with glutathione (Ki:4.2×10^-6 M). In addition, this compound also has anti-bacterial activity against Gram-positive bacteria including methicillin-resistant Staphylococcus aureus (MRSA).
Storage	-20°C	CAS	138968-86-2
Link	Bioactive Compounds

[Date : May 16 2025 00:07]

Benastatin B, Glutathione S-Transferase (GST) Inhibitor

DatasheetThis may not be the latest data sheet.

Product Code: 14653
Supplier: IMC
Size: 1mg
Price: $500

Description	M.W.: 502.563 Purity : > 95％ (HPLC) Molecular Formula : C30H30O7 Solubility : Soluble in DMSO, Poorly soluble in MeOH, Acetone, EtOAc, Insoluble in H2O. Benastatin B exhibited competitive inhibitory activity with 3,4-dichloronitrobenzene (Ki:3.7×10^-6 M), and noncompetitive with glutathione (Ki:4.2×10^-6 M). In addition, this compound also has anti-bacterial activity against Gram-positive bacteria including methicillin-resistant Staphylococcus aureus (MRSA).
Storage	-20°C	CAS	138968-86-2
Link	Bioactive Compounds

Contact

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