HOME> Products> Natural and Chemical compound> Other natural compound> Bequinostatin A

Glutathione S-transferase inhibitor Bequinostatin A

Date:April 14 2022Web Page No:95019

Bequinostatin A is isolated from the culture broth of Streptomyces sp. MI384-DF12, and it has a significant inhibitory activity against human Π(pi) class glutathione S-transferase (GSTπ) expressed in carcinogenesis (IC50: 4.6 ug/mL) 1).


Bequinostatin A

Specification

CAS#151013-37-5
Molecular FormulaC28H24O9
Molecular Weight504.491
SourceStreptomyces sp. MI384-DF12
Purity>75% (HPLC) (contains about 20% Bequinostatin C)
SolubilitySoluble in DMSO, MeOH and Pyridine. Insoluble in H2O

Go back to index

Application Note

  • Bequinostatin A exhibits no toxicity after intraperitoneal injection in mice at a dose of 100 mg/kg 1).
  • The absolute stereochemistry of the hydroxyl group was determined by the X-ray diffraction analysis 2).

Note: Bequinostatin A seems to change to Bequinostatin C slowly in the solution condition. The stock solution should be stored at 4˚C or lower, and should be used within a couple of days.

Go back to index

Reference


IMC banner

[Date : June 25 2024 00:08]

Detail Product Name Product Code Supplier Size Price
Bequinostatin A,Glutathione S-Transferase (GST) π Class Inhibitor
DatasheetThis may not be the latest data sheet.
14681 IMCInstitute of Microbial Chemistry 1 mg $500

Description
Storage -20°C CAS 151013-37-5
Link

Bioactive Compounds

[Date : June 25 2024 00:08]

Bequinostatin A,Glutathione S-Transferase (GST) π Class Inhibitor


  • Product Code: 14681
  • Supplier: IMC
  • Size: 1mg
  • Price: $500

Description
Storage -20°C CAS 151013-37-5
Link

Bioactive Compounds

Go back to index

CONTACT

export@funakoshi.co.jp

  • Prices are for USA / Canada customers. Prices do not include shipping and handling charges, VAT, import tariffs and service charge etc.
  • Please note that Product Information or Price may change without notice.