HOME> Products> Natural and Chemical compound> Benanomicin B

Anti-HIV and anti-fungal activity Benanomicin B

Date:July 03 2020Web Page No:520047

Benanomicin B is an antibiotic isolated from the culture fluid of Actinomadura sp. MH193-16F4.1,2)
Benanomicin B prevented human T-cells from HIV-1 at 10~100 µg/mL and inhibited syncytium formation by HIV-1 at 10~100 µg/mL.3) The antifungal and anti HIV-1 activities of benanomicins and their analogues have been studied.4) It also showed good antibacterial activity against Candida, Cryptococcus and Saccharomyces, etc.

Benanomicin B

Specification

CAS#116249-66-2
Molecular FormulaC39H42N2O18
Molecular Weight826.761
SourceActinomadura sp. MH193-16F4
Purity> 90% (HPLC)
Long Term Storageat - 20 °C
SolubilitySoluble in DMSO. Insoluble in H2O.


Go back to index

Application Note

  • Exhibited the following antimicrobial activity(MIC) 1,4):
    Cryptococcus neoformans F-10 1.56 μg/ml, Candida pseudotropicalis F-2 6.25 μg/mL, Candida kusei F-5 6.25 μg/ml, Candida sp. Yu-1200 6.25 μg/ml, Saccharomyces cerevisiae F-7 6.25 μg/ml
  • Inhibited infection of human T-cells with human immunodeficiency virus (HIV-1) at 10~100 µg/mL.3)

Go back to index

Reference

  1. Takeuchi T. et al. J. Antibiot., 41(6), 807~811 (1988).
  2. Gomi S. et al. J. Antibiot., 41(8), 1019~1028 (1988).
  3. Hoshino H. et al. J. Antibiot., 42(2), 344~346 (1989).
  4. Kondo S. et al. J. Antibiot., 44(11), 1228~1236 (1991).

IMC banner

[Date : July 23 2024 00:06]

Detail Product Name Product Code Supplier Size Price
Benanomicin B,Antifungal
DatasheetThis may not be the latest data sheet.
02968 IMCInstitute of Microbial Chemistry 1 mg $500

Description
Storage -20°C CAS 116249-66-2 (free form)
Link

Bioactive Compounds

[Date : July 23 2024 00:06]

Benanomicin B,Antifungal


  • Product Code: 02968
  • Supplier: IMC
  • Size: 1mg
  • Price: $500

Description
Storage -20°C CAS 116249-66-2 (free form)
Link

Bioactive Compounds

Go back to index

CONTACT

export@funakoshi.co.jp

  • Prices on our website are for your reference only. Please inquire your distributor for your prices.
  • Please note that Product Information or Price may change without notice.