TNF-α, Human, HS Quantikine ELISA Kit, 5th Generation
掲載日情報：2018/02/01 現在Webページ番号：206226
R&D Systems製のTNF-α, Human, HS, 5th Generationを測定するELISAキットです。
※本製品は研究用です。研究用以外には使用できません。
[在庫・価格 ：2025年04月26日 00時00分現在]
※ 表示されている納期は弊社に在庫が無く、取り寄せた場合の納期目安となります。
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TNF-α, Human, ELISA Kit, Quantikine HS, 5th Generation (96well) |
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TNF-α, Human, ELISA Kit, Quantikine HS, 5th Generation, SixPak (6×96well) |
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[在庫・価格 ：2025年04月26日 00時00分現在]
※ 表示されている納期は弊社に在庫が無く、取り寄せた場合の納期目安となります。
TNF-α, Human, ELISA Kit, Quantikine HS, 5th Generation (96well)
文献数： 192
- 商品コード：HSTA00E
- メーカー：RSD
- 包装：1kit
- 価格：¥124,000
- 在庫：1個
- 納期：10日程度 ※※ 表示されている納期は弊社に在庫がなく、取り寄せた場合の目安納期となります。
- 法規制等：
| 説明文 | 使用文献あり。測定範囲：0.156-10 pg/mL，感度：0.049 pg/mL，測定試料：Serum, Plasma，種交差性：Human，検出方法：呈色，測定波長：450 nm，アッセイ法：サンドイッチELISA，アッセイ数：96 well，測定時間：4.0 hours，測定因子：TNF-alpha High Sensitivity 別名：APC1 protein Genbank No： 7124 |
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| 保存条件 | 4℃ | 法規備考 | |
| 掲載カタログ |
ニュース2021年5月1日号 p.7
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| 製品記事 | TNF-α ELISA Kit（R&D Systems 社） 新型コロナウイルス感染に起因するサイトカインストームのモニタリング用製品 Helper T Cells Marker Antibodies MASLD / MASH研究用試薬 ELISA Kit製品に関するFAQ（R&D Systems） 日本語マニュアル配布中！ |
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| 関連記事 | R&D Systems Quantikine ELISA Kit／DuoSet Kit特集 Quantikine ELISA Kit |
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TNF-α, Human, ELISA Kit, Quantikine HS, 5th Generation, SixPak (6×96well)
文献数： 0
- 商品コード：SSTA00E
- メーカー：RSD
- 包装：1pack
- 価格：ご照会ください
- 在庫：無(未発注)
- 納期：ご照会下さい ※※ 表示されている納期は弊社に在庫がなく、取り寄せた場合の目安納期となります。
- 法規制等：
| 説明文 | 感度：0.049 pg/mL，測定範囲：0.16 - 10 pg/mL，測定試料：Serum (50 uL), EDTA Plasma (50 uL), Heparin Plasma (50 uL)，種交差性：Human，検出方法：colorimetric，測定波長：450 nm，アッセイ法：Sandwich，アッセイ数：576，別売品コントロール：QC232，測定時間：4.0 hours，測定因子：TNF-alpha 別名：APC1 protein Genbank No： 7124 |
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| 法規制等 | |||
| 保存条件 | 4℃ | 法規備考 | |
| 掲載カタログ |
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| 製品記事 | Helper T Cells Marker Antibodies ELISA Kit製品に関するFAQ（R&D Systems） |
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| 関連記事 | R&D Systems Quantikine ELISA Kit／DuoSet Kit特集 Quantikine ELISA Kit |
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Product Details
- Assay Length
- 4 hours
- Sample Type & Volume Required Per Well
- Serum (50 uL), EDTA Plasma (50 uL), Heparin Plasma (50 uL)
- Sensitivity
- 0.049 pg/mL
- Assay Range
- 0.2 - 10 pg/mL (Serum, EDTA Plasma, Heparin Plasma)
- Specificity
- Natural and recombinant human TNF-alpha
- Interference
- No significant interference observed with available related molecules.
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Product Summary
The Quantikine HS Human TNF-alpha Immunoassay is a 6.5 hour solid phase ELISA designed to measure TNF-alpha in serum and plasma. It contains E. coli-derived recombinant human TNF-alpha and antibodies raised against the recombinant factor. It has been shown to accurately quantitate recombinant human TNF-alpha. Results obtained with naturally occurring TNF-alpha samples showed linear curves that were parallel to the standard curves obtained using the recombinant kit standards. These results indicate that this kit can be used to determine relative mass values for natural TNF-alpha. Since the measurement of TNF-alpha is insensitive to the addition of recombinant forms of either of the two types of soluble receptors, it is probable that this measurement detects the total amount of TNF-alpha in samples, i.e., the total amount of free TNF-alpha plus the amount of TNF-alpha bound to soluble receptors.
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Precision
Intra-Assay Precision (Precision within an assay) Three samples of known concentration were tested on one plate to assess intra-assay precision.Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.Three samples of known concentration were tested twenty times on one plate to assess intra-assay precisionInter-Assay Precision (Precision between assays) Three samples of known concentration were tested in separate assays to assess inter-assay precision.Three samples of known concentration were tested in twenty separate assays to assess inter-assay precision. Assays were performed by at least three technicians using two lots of components.Three samples of known concentration were tested in twenty separate assays to assess inter-assay precision. Assays were performed by at least three technicians using two lots of components
Serum, EDTA Plasma, Heparin Plasma, Citrate Plasma
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Recovery
The recovery of TNF-alpha was determined by spiking to three different levels throughout the range of the assay in various matrices.
| Sample Type | Average % Recovery | Range % |
|---|---|---|
| EDTA Plasma (n=4) | 97 | 80-111 |
| Heparin Plasma (n=4) | 96 | 80-111 |
| Serum (n=4) | 94 | 83-103 |
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Linearity
To assess the linearity of the assay, samples were spiked with high concentrations of TNF-alpha and diluted with Calibrator Diluent to produce samples with values within the dynamic range of the assay.
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Additional Infomation
- Entrez Gene IDs
- 7124 (Human); 21926 (Mouse); 24835 (Rat); 397086 (Porcine); 280943 (Bovine); 403922 (Canine); 100033834 (Equine); 493755 (Feline); 100009088 (Rabbit)
- Background
- TNF-alpha
- Tumor necrosis factor alpha (TNF-α), also known as cachectin and TNFSF2, is the prototypic ligand of the TNF superfamily. It is a pleiotropic molecule that plays a central role in inflammation, apoptosis, and immune system development. TNF-α is produced by a wide variety of immune and epithelial cell types. Human TNF-α consists of a 35 amino acid (aa) cytoplasmic domain, a 21 aa transmembrane segment, and a 177 aa extracellular domain (ECD). Within the ECD, human TNF-α shares 97% aa sequence identity with rhesus and 71% - 92% with bovine, canine, cotton rat, equine, feline, mouse, porcine, and rat TNF-α. The 26 kDa type 2 transmembrane protein is assembled intracellularly to form a noncovalently linked homotrimer. Ligation of this complex induces reverse signaling that promotes lymphocyte costimulation but diminishes monocyte responsiveness. Cleavage of membrane bound TNF-α by TACE/ADAM17 releases a 55 kDa soluble trimeric form of TNF-α. TNF-α trimers bind the ubiquitous TNF RI and the hematopoietic cell-restricted TNF RII, both of which are also expressed as homotrimers. TNF-α regulates lymphoid tissue development through control of apoptosis. It also promotes inflammatory responses by inducing the activation of vascular endothelial cells and macrophages. TNF-α is a key cytokine in the development of several inflammatory disorders. It contributes to the development of type 2 diabetes through its effects on insulin resistance and fatty acid metabolism.
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Citations
R&D Systems personnel manually curate a database that contains references using R&D Systems products.The data collected includes not only links to publications in PubMed,but also provides information about sample types, species, and experimental conditions.
Repeated Excessive Exercise Attenuates the Anti-Inflammatory Effects of Exercise in Older Men
Authors: RE Sahl, PR Andersen, K Gronbaek, TH Morville, M Rosenkilde, HK Rasmusen, SS Poulsen, C Prats, F Dela, JW Helge
Front Physiol, 2017;8(0):407.
Species: Human
Sample Type: Plasma
Authors: RE Sahl, PR Andersen, K Gronbaek, TH Morville, M Rosenkilde, HK Rasmusen, SS Poulsen, C Prats, F Dela, JW Helge
Front Physiol, 2017;8(0):407.
Species: Human
Sample Type: Plasma
Association of plasma CD40L with acute chest syndrome in sickle cell anemia
Authors: VT Garrido, L Sonzogni, SN Mtatiro, FF Costa, N Conran, SL Thein
Cytokine, 2017;97(0):104-107.
Species: Human
Sample Type: Plasma
Authors: VT Garrido, L Sonzogni, SN Mtatiro, FF Costa, N Conran, SL Thein
Cytokine, 2017;97(0):104-107.
Species: Human
Sample Type: Plasma
Chemokine signals are crucial for enhanced homing and differentiation of circulating osteoclast progenitor cells
Authors: A Sucur, Z Jajic, M Artukovic, MI Matijasevi, B Anic, D Flegar, A Markotic, T Kelava, S Ivcevic, N Kovacic, V Katavic, D Grcevic
Arthritis Res. Ther., 2017;19(1):142.
Species: Human
Sample Type: Plasma
Authors: A Sucur, Z Jajic, M Artukovic, MI Matijasevi, B Anic, D Flegar, A Markotic, T Kelava, S Ivcevic, N Kovacic, V Katavic, D Grcevic
Arthritis Res. Ther., 2017;19(1):142.
Species: Human
Sample Type: Plasma
Microenvironment inflammatory infiltrate drives growth speed and outcome of hepatocellular carcinoma: a prospective clinical study
Authors: R Critelli, F Milosa, F Faillaci, R Condello, E Turola, L Marzi, B Lei, F Dituri, S Andreani, P Sighinolfi, P Manni, A Maiorana, C Caporali, F di Benedet, M Del Buono, N De Maria, F Schepis, ML Martinez-C, G Giannelli, E Villa
Cell Death Dis, 2017;8(8):e3017.
Species: Human
Sample Type: Serum
Authors: R Critelli, F Milosa, F Faillaci, R Condello, E Turola, L Marzi, B Lei, F Dituri, S Andreani, P Sighinolfi, P Manni, A Maiorana, C Caporali, F di Benedet, M Del Buono, N De Maria, F Schepis, ML Martinez-C, G Giannelli, E Villa
Cell Death Dis, 2017;8(8):e3017.
Species: Human
Sample Type: Serum
Visceral fat area is a strong predictor of leukocyte cell-derived chemotaxin 2, a potential biomarker of dyslipidemia
Authors: K Tanisawa, H Taniguchi, X Sun, T Ito, R Kawakami, S Sakamoto, M Higuchi
PLoS ONE, 2017;12(3):e0173310.
Species: Human
Sample Type: Serum
Authors: K Tanisawa, H Taniguchi, X Sun, T Ito, R Kawakami, S Sakamoto, M Higuchi
PLoS ONE, 2017;12(3):e0173310.
Species: Human
Sample Type: Serum
Effects of nateglinide and rosiglitazone on pancreatic alpha- and beta-cells,GLP-1 secretion and inflammatory markers in patients with type 2 diabetes:randomized crossover clinical study.
Authors: Tostes G, Cunha M, Fukui R, Correia M, Rocha D, Dos Santos R, da Silva M
Diabetol Metab Syndr, 2016;8(0):1.
Species: Human
Sample Type: Serum
Authors: Tostes G, Cunha M, Fukui R, Correia M, Rocha D, Dos Santos R, da Silva M
Diabetol Metab Syndr, 2016;8(0):1.
Species: Human
Sample Type: Serum
The relationship between circulating neutrophil gelatinase-associated lipocalin and early alteration of metabolic parameters is associated with dietary saturated fat intake in non-diabetic Korean women
Authors: GY Na, SR Yoon, J An, R Yeo, J Song, MN Jo, S Han, OY Kim
Endocr. J, 2016;0(0):.
Species: Human
Sample Type: Plasma
Authors: GY Na, SR Yoon, J An, R Yeo, J Song, MN Jo, S Han, OY Kim
Endocr. J, 2016;0(0):.
Species: Human
Sample Type: Plasma
Anti-TNF-? Drugs Differently Affect the TNF?-sTNFR System and Monocyte Subsets in Patients with Psoriasis
PLoS ONE, 2016;11(12):e0167757.
PLoS ONE, 2016;11(12):e0167757.
Local TNF causes NFATc1-dependent cholesterol-mediated podocyte injury
J Clin Invest, 2016;0(0):.
Species: Human
Sample Type: Serum
J Clin Invest, 2016;0(0):.
Species: Human
Sample Type: Serum
Casein glycomacropeptide for active distal ulcerative colitis: a randomised pilot study
Authors: CL Hvas, A Dige, M Bendix, PG Wernlund, LA Christense, JF Dahlerup, J Agnholt
Eur J Clin Invest, 2016;0(0):.
Species: Human
Sample Type: Plasma
Authors: CL Hvas, A Dige, M Bendix, PG Wernlund, LA Christense, JF Dahlerup, J Agnholt
Eur J Clin Invest, 2016;0(0):.
Species: Human
Sample Type: Plasma
Trait Hostility and Acute Inflammatory Responses to Stress in the Laboratory
Authors: Dominique Girard
PLoS ONE, 2016;11(6):e0156329.
Species: Human
Sample Type: Serum
Authors: Dominique Girard
PLoS ONE, 2016;11(6):e0156329.
Species: Human
Sample Type: Serum
Reduction of c-Fos via Overexpression of miR-34a Results in Enhancement of TNF- Production by LPS in Neutrophils from Myelodysplastic Syndrome Patients
PLoS ONE, 2016;11(8):e0158527.
Species: Human
Sample Type: Cell Culture Supernates
PLoS ONE, 2016;11(8):e0158527.
Species: Human
Sample Type: Cell Culture Supernates
Circadian misalignment increases cardiovascular disease risk factors in humans
Proc. Natl. Acad. Sci. U.S.A., 2016;113(10):E1402-11.
Species: Human
Sample Type: Serum
Proc. Natl. Acad. Sci. U.S.A., 2016;113(10):E1402-11.
Species: Human
Sample Type: Serum
Interleukin-6 Is a Risk Factor for Atrial Fibrillation in Chronic Kidney Disease:Findings from the CRIC Study.
Authors: Amdur R, Mukherjee M, Go A, Barrows I, Ramezani A, Shoji J, Reilly M, Gnanaraj J, Deo R, Roas S, Keane M, Master S, Teal V, Soliman E, Yang P, Feldman H, Kusek J, Tracy C, Raj D
PLoS ONE, 2016;11(2):e0148189.
Species: Human
Sample Type: Plasma
Authors: Amdur R, Mukherjee M, Go A, Barrows I, Ramezani A, Shoji J, Reilly M, Gnanaraj J, Deo R, Roas S, Keane M, Master S, Teal V, Soliman E, Yang P, Feldman H, Kusek J, Tracy C, Raj D
PLoS ONE, 2016;11(2):e0148189.
Species: Human
Sample Type: Plasma
Plasma TNF-alpha and Soluble TNF Receptor Levels after Doxorubicin with orwithout Co-Administration of Mesna-A Randomized, Cross-Over Clinical Study.
Authors: Hayslip J, Dressler E, Weiss H, Taylor T, Chambers M, Noel T, Miriyala S, Keeney J, Ren X, Sultana R, Vore M, Butterfield D, St Clair D, Moscow J
PLoS ONE, 2015;10(4):e0124988.
Species: Human
Sample Type: Plasma
Authors: Hayslip J, Dressler E, Weiss H, Taylor T, Chambers M, Noel T, Miriyala S, Keeney J, Ren X, Sultana R, Vore M, Butterfield D, St Clair D, Moscow J
PLoS ONE, 2015;10(4):e0124988.
Species: Human
Sample Type: Plasma
A randomized, placebo controlled trial of omega-3 fatty acids in the treatment ofyoung children with autism.
Authors: Mankad D, Dupuis A, Smile S, Roberts W, Brian J, Lui T, Genore L, Zaghloul D, Iaboni A, Marcon P, Anagnostou E
Mol Autism, 2015;6(0):18.
Species: Human
Sample Type: Plasma
Authors: Mankad D, Dupuis A, Smile S, Roberts W, Brian J, Lui T, Genore L, Zaghloul D, Iaboni A, Marcon P, Anagnostou E
Mol Autism, 2015;6(0):18.
Species: Human
Sample Type: Plasma
Effects of Acute Endurance Exercise Performed in the Morning and Evening onInflammatory Cytokine and Metabolic Hormone Responses.
Authors: Kim H, Konishi M, Takahashi M, Tabata H, Endo N, Numao S, Lee S, Kim Y, Suzuki K, Sakamoto S
PLoS ONE, 2015;10(9):e0137567.
Species: Human
Sample Type: Plasma
Authors: Kim H, Konishi M, Takahashi M, Tabata H, Endo N, Numao S, Lee S, Kim Y, Suzuki K, Sakamoto S
PLoS ONE, 2015;10(9):e0137567.
Species: Human
Sample Type: Plasma
Sclerostin, TNF-alpha and Interleukin-18 Correlate and are Together with KlothoRelated to Other Growth Factors and Cytokines in Haemodialysis Patients.
Authors: Almroth G, Lonn J, Uhlin F, Brudin L, Andersson B, Hahn-Zoric M
Scand J Immunol, 2015;83(1):58-63.
Species: Human
Sample Type: Serum
Authors: Almroth G, Lonn J, Uhlin F, Brudin L, Andersson B, Hahn-Zoric M
Scand J Immunol, 2015;83(1):58-63.
Species: Human
Sample Type: Serum
Tumor-specific cytotoxic T lymphocyte activity determines colorectal cancerpatient prognosis.
Authors: Reissfelder C, Stamova S, Gossmann C, Braun M, Bonertz A, Walliczek U, Grimm M, Rahbari N, Koch M, Saadati M, Benner A, Buchler M, Jager D, Halama N, Khazaie K, Weitz J, Beckhove P
J Clin Invest, 2015;125(2):739-51.
Species: Human
Sample Type: Tissue Homogenates
Authors: Reissfelder C, Stamova S, Gossmann C, Braun M, Bonertz A, Walliczek U, Grimm M, Rahbari N, Koch M, Saadati M, Benner A, Buchler M, Jager D, Halama N, Khazaie K, Weitz J, Beckhove P
J Clin Invest, 2015;125(2):739-51.
Species: Human
Sample Type: Tissue Homogenates
Differential Patterns and Determinants of Cardiac Autonomic Nerve Dysfunctionduring Endotoxemia and Oral Fat Load in Humans.
Authors: Ziegler D, Strom A, Strassburger K, Nowotny B, Zahiragic L, Nowotny P, Carstensen-Kirberg M, Herder C, Szendroedi J, Roden M
PLoS ONE, 2015;10(4):e0124242.
Species: Human
Sample Type: Serum
Authors: Ziegler D, Strom A, Strassburger K, Nowotny B, Zahiragic L, Nowotny P, Carstensen-Kirberg M, Herder C, Szendroedi J, Roden M
PLoS ONE, 2015;10(4):e0124242.
Species: Human
Sample Type: Serum
Effects of pentoxifylline on proteinuria and glucose control in patients withtype 2 diabetes: a prospective randomized double-blind multicenter study.
Authors: Han S, Kim H, Kim D, Sheen S, Chung C, Ahn C, Kim S, Cho Y, Park S, Kim S, Kim C, Kim K, Lee K
Diabetol Metab Syndr, 2015;7(0):64.
Species: Human
Sample Type: Serum
Authors: Han S, Kim H, Kim D, Sheen S, Chung C, Ahn C, Kim S, Cho Y, Park S, Kim S, Kim C, Kim K, Lee K
Diabetol Metab Syndr, 2015;7(0):64.
Species: Human
Sample Type: Serum
Association of Sarcopenic Obesity with Higher Serum High-Sensitivity C-ReactiveProtein Levels in Chinese Older Males--A Community-Based Study (TaichungCommunity Health Study-Elderly, TCHS-E).
Authors: Yang C, Li C, Li T, Liu C, Lin C, Lin W, Lin C
PLoS ONE, 2015;10(7):e0132908.
Species: Human
Sample Type: Serum
Authors: Yang C, Li C, Li T, Liu C, Lin C, Lin W, Lin C
PLoS ONE, 2015;10(7):e0132908.
Species: Human
Sample Type: Serum
Disturbances in Hypothalamic-Pituitary-Adrenal Axis and Immunological ActivityDifferentiating between Unipolar and Bipolar Depressive Episodes.
Authors: Becking K, Spijker A, Hoencamp E, Penninx B, Schoevers R, Boschloo L
PLoS ONE, 2015;10(7):e0133898.
Species: Human
Sample Type: Plasma
Authors: Becking K, Spijker A, Hoencamp E, Penninx B, Schoevers R, Boschloo L
PLoS ONE, 2015;10(7):e0133898.
Species: Human
Sample Type: Plasma
Association between Inflammation and Cardiac Geometry in Chronic Kidney Disease: Findings from the CRIC Study.
Authors: Gupta J, Dominic E, Fink J, Ojo A, Barrows I, Reilly M, Townsend R, Joffe M, Rosas S, Wolman M, Patel S, Keane M, Feldman H, Kusek J, Raj D
PLoS ONE, 2015;10(4):e0124772.
Species: Human
Sample Type: Plasma
Authors: Gupta J, Dominic E, Fink J, Ojo A, Barrows I, Reilly M, Townsend R, Joffe M, Rosas S, Wolman M, Patel S, Keane M, Feldman H, Kusek J, Raj D
PLoS ONE, 2015;10(4):e0124772.
Species: Human
Sample Type: Plasma
Tumor necrosis factor-alpha confers cardioprotection through ectopic expressionof keratins K8 and K18.
Authors: Papathanasiou S, Rickelt S, Soriano M, Schips T, Maier H, Davos C, Varela A, Kaklamanis L, Mann D, Capetanaki Y
Nat Med, 2015;21(9):1076-84.
Species: Human
Sample Type: Serum
Authors: Papathanasiou S, Rickelt S, Soriano M, Schips T, Maier H, Davos C, Varela A, Kaklamanis L, Mann D, Capetanaki Y
Nat Med, 2015;21(9):1076-84.
Species: Human
Sample Type: Serum
Compartment differences of inflammatory activity in chronic obstructive pulmonarydisease.
Authors: Ji J, von Scheele I, Bergstrom J, Billing B, Dahlen B, Lantz A, Larsson K, Palmberg L
Respir Res, 2014;15(0):104.
Species: Human
Sample Type: Serum
Authors: Ji J, von Scheele I, Bergstrom J, Billing B, Dahlen B, Lantz A, Larsson K, Palmberg L
Respir Res, 2014;15(0):104.
Species: Human
Sample Type: Serum
Zinc supplementation improves anticancer activity of monocytes in type-2 diabeticpatients with metabolic syndrome.
Authors: Meksawan K, Sermsri U, Chanvorachote P
Anticancer Res, 2014;34(1):295-9.
Species: Human
Sample Type: Plasma
Authors: Meksawan K, Sermsri U, Chanvorachote P
Anticancer Res, 2014;34(1):295-9.
Species: Human
Sample Type: Plasma
The protective effect of esculentoside a on experimental acute liver injury inmice.
Authors: Zhang F, Wang X, Qiu X, Wang J, Fang H, Wang Z, Sun Y, Xia Z
PLoS ONE, 2014;9(11):e113107.
Species: Human
Sample Type: Cell Culture Supernates
Authors: Zhang F, Wang X, Qiu X, Wang J, Fang H, Wang Z, Sun Y, Xia Z
PLoS ONE, 2014;9(11):e113107.
Species: Human
Sample Type: Cell Culture Supernates
Threonyl-tRNA synthetase overexpression correlates with angiogenic markers andprogression of human ovarian cancer.
Authors: Wellman T, Eckenstein M, Wong C, Rincon M, Ashikaga T, Mount S, Francklyn C, Lounsbury K
BMC Cancer, 2014;14(0):620.
Species: Human
Sample Type: Serum
Authors: Wellman T, Eckenstein M, Wong C, Rincon M, Ashikaga T, Mount S, Francklyn C, Lounsbury K
BMC Cancer, 2014;14(0):620.
Species: Human
Sample Type: Serum
Role of diacylglycerol activation of PKCtheta in lipid-induced muscle insulinresistance in humans.
Authors: Szendroedi J, Yoshimura T, Phielix E, Koliaki C, Marcucci M, Zhang D, Jelenik T, Muller J, Herder C, Nowotny P, Shulman G, Roden M
Proc Natl Acad Sci U S A, 2014;111(26):9597-602.
Species: Human
Sample Type: Plasma
Authors: Szendroedi J, Yoshimura T, Phielix E, Koliaki C, Marcucci M, Zhang D, Jelenik T, Muller J, Herder C, Nowotny P, Shulman G, Roden M
Proc Natl Acad Sci U S A, 2014;111(26):9597-602.
Species: Human
Sample Type: Plasma
Circulating mitochondrial DNA increases with age and is a familiar trait: Implications for "inflamm-aging"
Authors: Pinti M, Cevenini E, Nasi M, De Biasi S, Salvioli S, Monti D, Benatti S, Gibellini L, Cotichini R, Stazi M, Trenti T, Franceschi C, Cossarizza A
Eur J Immunol, 2014;44(5):1552-62.
Species: Human
Sample Type: Plasma
Authors: Pinti M, Cevenini E, Nasi M, De Biasi S, Salvioli S, Monti D, Benatti S, Gibellini L, Cotichini R, Stazi M, Trenti T, Franceschi C, Cossarizza A
Eur J Immunol, 2014;44(5):1552-62.
Species: Human
Sample Type: Plasma
The impact of two different transfusion strategies on patient immune response during major abdominal surgery: a preliminary report.
Authors: Theodoraki K, Markatou M, Rizos D, Fassoulaki A
J Immunol Res, 2014;2014(0):945829.
Species: Human
Sample Type: Plasma
Authors: Theodoraki K, Markatou M, Rizos D, Fassoulaki A
J Immunol Res, 2014;2014(0):945829.
Species: Human
Sample Type: Plasma
High-salt intake induced visceral adipose tissue hypoxia and its association withcirculating monocyte subsets in humans.
Authors: Zhou X, Yuan F, Ji W, Guo Z, Zhang L, Lu R, Liu X, Liu H, Zhang W, Jiang T, Zhang Z, Li Y
Obesity (Silver Spring), 2014;22(6):1470-6.
Species: Human
Sample Type: Serum
Authors: Zhou X, Yuan F, Ji W, Guo Z, Zhang L, Lu R, Liu X, Liu H, Zhang W, Jiang T, Zhang Z, Li Y
Obesity (Silver Spring), 2014;22(6):1470-6.
Species: Human
Sample Type: Serum
Smac mimetics and innate immune stimuli synergize to promote tumor death.
Authors: Beug S, Tang V, Lacasse E, Cheung H, Beauregard C, Brun J, Nuyens J, Earl N, St-Jean M, Holbrook J, Dastidar H, Mahoney D, Ilkow C, Le Boeuf F, Bell J, Korneluk R
Nat Biotechnol, 2014;32(2):182-90.
Species: Human
Sample Type: Cell Culture Supernates
Authors: Beug S, Tang V, Lacasse E, Cheung H, Beauregard C, Brun J, Nuyens J, Earl N, St-Jean M, Holbrook J, Dastidar H, Mahoney D, Ilkow C, Le Boeuf F, Bell J, Korneluk R
Nat Biotechnol, 2014;32(2):182-90.
Species: Human
Sample Type: Cell Culture Supernates
Race modifies the association between adiposity and inflammation in patients withchronic kidney disease: findings from the chronic renal insufficiency cohortstudy.
Authors: Wing M, Yang W, Teal V, Navaneethan S, Tao K, Ojo A, Guzman N, Reilly M, Wolman M, Rosas S, Cuevas M, Fischer M, Lustigova E, Master S, Xie D, Appleby D, Joffe M, Kusek J, Feldman H, Raj D
Obesity (Silver Spring), 2014;22(5):1359-66.
Species: Human
Sample Type: Plasma
Authors: Wing M, Yang W, Teal V, Navaneethan S, Tao K, Ojo A, Guzman N, Reilly M, Wolman M, Rosas S, Cuevas M, Fischer M, Lustigova E, Master S, Xie D, Appleby D, Joffe M, Kusek J, Feldman H, Raj D
Obesity (Silver Spring), 2014;22(5):1359-66.
Species: Human
Sample Type: Plasma
Big breakfast rich in protein and fat improves glycemic control in type 2 diabetics.
Authors: Rabinovitz H, Boaz M, Ganz T, Jakubowicz D, Matas Z, Madar Z, Wainstein J
Obesity (Silver Spring), 2014;22(5):E46-54.
Species: Human
Sample Type: Plasma
Authors: Rabinovitz H, Boaz M, Ganz T, Jakubowicz D, Matas Z, Madar Z, Wainstein J
Obesity (Silver Spring), 2014;22(5):E46-54.
Species: Human
Sample Type: Plasma
Association between traffic-related air pollution, subclinical inflammation andimpaired glucose metabolism: results from the SALIA study.
Authors: Teichert T, Vossoughi M, Vierkotter A, Sugiri D, Schikowski T, Schulte T, Roden M, Luckhaus C, Herder C, Kramer U
PLoS ONE, 2013;8(12):e83042.
Species: Human
Sample Type: Plasma
Authors: Teichert T, Vossoughi M, Vierkotter A, Sugiri D, Schikowski T, Schulte T, Roden M, Luckhaus C, Herder C, Kramer U
PLoS ONE, 2013;8(12):e83042.
Species: Human
Sample Type: Plasma
Engulfment of hematopoietic stem cells caused by down-regulation of CD47 iscritical in the pathogenesis of hemophagocytic lymphohistiocytosis.
Authors: Kuriyama T, Takenaka K, Kohno K, Yamauchi T, Daitoku S, Yoshimoto G, Kikushige Y, Kishimoto J, Abe Y, Harada N, Miyamoto T, Iwasaki H, Teshima T, Akashi K
Blood, 2012;120(19):4058-67.
Species: Human
Sample Type: Serum
Authors: Kuriyama T, Takenaka K, Kohno K, Yamauchi T, Daitoku S, Yoshimoto G, Kikushige Y, Kishimoto J, Abe Y, Harada N, Miyamoto T, Iwasaki H, Teshima T, Akashi K
Blood, 2012;120(19):4058-67.
Species: Human
Sample Type: Serum
Multiplexing immunoassays for cytokine detection in the serum of patients with rheumatoid arthritis: lack of sensitivity and interference by rheumatoid factor.
Authors: Churchman SM, Geiler J, Parmar R, Horner EA, Church LD, Emery P, Buch MH, McDermott MF, Ponchel F
Clin. Exp. Rheumatol., 2012;30(4):534-42.
Species: Human
Sample Type: Serum
Authors: Churchman SM, Geiler J, Parmar R, Horner EA, Church LD, Emery P, Buch MH, McDermott MF, Ponchel F
Clin. Exp. Rheumatol., 2012;30(4):534-42.
Species: Human
Sample Type: Serum
A randomized trial of recombinant human granulocyte-macrophage colony stimulating factor for patients with acute lung injury.
Authors: Paine R, Standiford TJ, Dechert RE, Moss M, Martin GS, Rosenberg AL, Thannickal VJ, Burnham EL, Brown MB, Hyzy RC
Crit. Care Med., 2012;40(1):90-7.
Species: Human
Sample Type: BALF
Authors: Paine R, Standiford TJ, Dechert RE, Moss M, Martin GS, Rosenberg AL, Thannickal VJ, Burnham EL, Brown MB, Hyzy RC
Crit. Care Med., 2012;40(1):90-7.
Species: Human
Sample Type: BALF
Fractalkine is an independent predictor of mortality in patients with advanced heart failure.
Thromb Haemost, 2012;108(6):1220-7.
Species: Human
Sample Type: Plasma
Thromb Haemost, 2012;108(6):1220-7.
Species: Human
Sample Type: Plasma
Adipocytokine levels mark endothelial function in normotensive individuals.
Authors: Solini A, Stea F, Santini E, Bruno R, Duranti E, Taddei S, Ghiadoni L
Cardiovasc Diabetol, 2012;11(0):103.
Species: Human
Sample Type: Plasma
Authors: Solini A, Stea F, Santini E, Bruno R, Duranti E, Taddei S, Ghiadoni L
Cardiovasc Diabetol, 2012;11(0):103.
Species: Human
Sample Type: Plasma
Mechanisms inducing low bone density in duchenne muscular dystrophy in mice and humans.
Authors: Rufo A, Del Fattore A, Capulli M, Carvello F, De Pasquale L, Ferrari S, Pierroz D, Morandi L, De Simone M, Rucci N, Bertini E, Bianchi ML, De Benedetti F, Teti A
J. Bone Miner. Res., 2011;26(8):1891-903.
Species: Human
Sample Type: Serum
Authors: Rufo A, Del Fattore A, Capulli M, Carvello F, De Pasquale L, Ferrari S, Pierroz D, Morandi L, De Simone M, Rucci N, Bertini E, Bianchi ML, De Benedetti F, Teti A
J. Bone Miner. Res., 2011;26(8):1891-903.
Species: Human
Sample Type: Serum
Effects of dietary fat modification on insulin sensitivity and on other risk factors of the metabolic syndrome-LIPGENE: a European randomized dietary intervention study.
Authors: Tierney AC, McMonagle J, Shaw DI, Gulseth HL, Helal O, Saris WH, Paniagua JA, Golabek-Leszczynska I, Defoort C, Williams CM, Karsltrom B, Vessby B, Dembinska-Kiec A, Lopez-Miranda J, Blaak EE, Drevon CA, Gibney MJ, Lovegrove JA, Roche HM
Int J Obes (Lond), 2011;35(6):800-9.
Species: Human
Sample Type: Serum
Authors: Tierney AC, McMonagle J, Shaw DI, Gulseth HL, Helal O, Saris WH, Paniagua JA, Golabek-Leszczynska I, Defoort C, Williams CM, Karsltrom B, Vessby B, Dembinska-Kiec A, Lopez-Miranda J, Blaak EE, Drevon CA, Gibney MJ, Lovegrove JA, Roche HM
Int J Obes (Lond), 2011;35(6):800-9.
Species: Human
Sample Type: Serum
Time-course of changes in inflammatory response after whole-body cryotherapy multi exposures following severe exercise.
Authors: Pournot H, Bieuzen F, Louis J, Fillard JR, Barbiche E, Hausswirth C
PLoS ONE, 2011;6(7):e22748.
Species: Human
Sample Type: Plasma
Authors: Pournot H, Bieuzen F, Louis J, Fillard JR, Barbiche E, Hausswirth C
PLoS ONE, 2011;6(7):e22748.
Species: Human
Sample Type: Plasma
Differential adaptation of human gut microbiota to bariatric surgery-induced weight loss: links with metabolic and low-grade inflammation markers.
Authors: Furet JP, Kong LC, Tap J, Poitou C, Basdevant A, Bouillot JL, Mariat D, Corthier G, Dore J, Henegar C, Rizkalla S, Clement K
Diabetes, 2010;59(12):3049-57.
Species: Human
Sample Type: Plasma
Authors: Furet JP, Kong LC, Tap J, Poitou C, Basdevant A, Bouillot JL, Mariat D, Corthier G, Dore J, Henegar C, Rizkalla S, Clement K
Diabetes, 2010;59(12):3049-57.
Species: Human
Sample Type: Plasma
Nonalcoholic fatty liver disease as the transducer of hepatic oversecretion of very-low-density lipoprotein-apolipoprotein B-100 in obesity.
Authors: Chan DC, Watts GF, Gan S
Arterioscler. Thromb. Vasc. Biol., 2010;30(5):1043-50.
Species: Human
Sample Type: Plasma
Authors: Chan DC, Watts GF, Gan S
Arterioscler. Thromb. Vasc. Biol., 2010;30(5):1043-50.
Species: Human
Sample Type: Plasma
Changes in cytokine levels during acute hyperinsulinemia in offspring of type 2 diabetic subjects.
Authors: Ruotsalainen E, Stancakova A, Vauhkonen I, Salmenniemi U, Pihlajamaki J, Punnonen K, Laakso M
Atherosclerosis, 2010;210(2):536-41.
Species: Human
Sample Type: Plasma
Authors: Ruotsalainen E, Stancakova A, Vauhkonen I, Salmenniemi U, Pihlajamaki J, Punnonen K, Laakso M
Atherosclerosis, 2010;210(2):536-41.
Species: Human
Sample Type: Plasma
B7-h3 augments the inflammatory response and is associated with human sepsis.
Authors: Zhang G, Wang J, Kelly J
J. Immunol., 2010;185(6):3677-84.
Species: Human
Sample Type: Plasma
Authors: Zhang G, Wang J, Kelly J
J. Immunol., 2010;185(6):3677-84.
Species: Human
Sample Type: Plasma
Sensitive plasma protein analysis by microparticle-based proximity ligation assays.
Authors: Darmanis S, Nong RY, Hammond M, Gu J, Alderborn A, Vanelid J, Siegbahn A, Gustafsdottir S, Ericsson O, Landegren U, Kamali-Moghaddam M
Mol. Cell Proteomics, 2010;9(2):327-35.
Species: Human
Sample Type: Plasma
Authors: Darmanis S, Nong RY, Hammond M, Gu J, Alderborn A, Vanelid J, Siegbahn A, Gustafsdottir S, Ericsson O, Landegren U, Kamali-Moghaddam M
Mol. Cell Proteomics, 2010;9(2):327-35.
Species: Human
Sample Type: Plasma
SIRT1 mRNA expression may be associated with energy expenditure and insulin sensitivity.
Authors: Rutanen J, Yaluri N, Modi S, Pihlajamaki J, Vanttinen M, Itkonen P, Kainulainen S, Yamamoto H, Lagouge M, Sinclair DA, Elliott P, Westphal C, Auwerx J, Laakso M
Diabetes, 2010;59(4):829-35.
Species: Human
Sample Type: Plasma
Authors: Rutanen J, Yaluri N, Modi S, Pihlajamaki J, Vanttinen M, Itkonen P, Kainulainen S, Yamamoto H, Lagouge M, Sinclair DA, Elliott P, Westphal C, Auwerx J, Laakso M
Diabetes, 2010;59(4):829-35.
Species: Human
Sample Type: Plasma
Prehospital resuscitation with hypertonic saline-dextran modulates inflammatory, coagulation and endothelial activation marker profiles in severe traumatic brain injured patients.
Authors: Rhind SG, Crnko NT, Baker AJ
J Neuroinflammation, 2010;7(0):5.
Species: Human
Sample Type: Serum
Authors: Rhind SG, Crnko NT, Baker AJ
J Neuroinflammation, 2010;7(0):5.
Species: Human
Sample Type: Serum
Procalcitonin as an early marker of bacterial infection in neutropenic febrile children with acute lymphoblastic leukemia.
Authors: Hatzistilianou M, Rekliti A, Athanassiadou F, Catriu D
Inflamm. Res., 2010;59(5):339-47.
Species: Human
Sample Type: Serum
Authors: Hatzistilianou M, Rekliti A, Athanassiadou F, Catriu D
Inflamm. Res., 2010;59(5):339-47.
Species: Human
Sample Type: Serum
Sex differences in inflammatory markers: what is the contribution of visceraladiposity?
Authors: Cartier A, Cote M, Lemieux I, Perusse L, Tremblay A, Bouchard C, Despres JP
Am. J. Clin. Nutr., 2009;89(5):1307-14.
Species: Human
Sample Type: Plasma
Authors: Cartier A, Cote M, Lemieux I, Perusse L, Tremblay A, Bouchard C, Despres JP
Am. J. Clin. Nutr., 2009;89(5):1307-14.
Species: Human
Sample Type: Plasma
Serum CXCL13 positively correlates with prostatic disease, prostate-specific antigen and mediates prostate cancer cell invasion, integrin clustering and cell adhesion.
Authors: Singh S, Singh R, Sharma PK, Singh UP, Rai SN, Chung LW, Cooper CR, Novakovic KR, Grizzle WE, Lillard JW
Cancer Lett., 2009;283(1):29-35.
Species: Human
Sample Type: Serum
Authors: Singh S, Singh R, Sharma PK, Singh UP, Rai SN, Chung LW, Cooper CR, Novakovic KR, Grizzle WE, Lillard JW
Cancer Lett., 2009;283(1):29-35.
Species: Human
Sample Type: Serum
Resistin, adiponectin, and risk of heart failure the Framingham offspring study.
Authors: Frankel DS, Vasan RS, D'Agostino RB, Benjamin EJ, Levy D, Wang TJ, Meigs JB
J. Am. Coll. Cardiol., 2009;53(9):754-62.
Species: Human
Sample Type: Plasma
Authors: Frankel DS, Vasan RS, D'Agostino RB, Benjamin EJ, Levy D, Wang TJ, Meigs JB
J. Am. Coll. Cardiol., 2009;53(9):754-62.
Species: Human
Sample Type: Plasma
Intervention of an inflammation amplifier, triggering receptor expressed on myeloid cells 1, for treatment of autoimmune arthritis.
Authors: Murakami Y, Akahoshi T, Aoki N, Toyomoto M, Miyasaka N, Kohsaka H
Arthritis Rheum., 2009;60(6):1615-23.
Species: Human
Sample Type: Serum
Authors: Murakami Y, Akahoshi T, Aoki N, Toyomoto M, Miyasaka N, Kohsaka H
Arthritis Rheum., 2009;60(6):1615-23.
Species: Human
Sample Type: Serum
Adiposity and gingival crevicular fluid tumour necrosis factor-alpha levels in children.
Authors: Khosravi R, Tran SD, Lambert M, O'Loughlin J, Kâ K, Feine JS, Caron C, Tremblay A, Nicolau B
J. Clin. Periodontol., 2009;36(4):301-7.
Species: Human
Sample Type: Gingival Crevicular Fluid (GCF)
Authors: Khosravi R, Tran SD, Lambert M, O'Loughlin J, Kâ K, Feine JS, Caron C, Tremblay A, Nicolau B
J. Clin. Periodontol., 2009;36(4):301-7.
Species: Human
Sample Type: Gingival Crevicular Fluid (GCF)
Characteristics of dengue virus-infected peripheral blood mononuclear cell death that correlates with the severity of illness.
Authors: Jaiyen Y, Masrinoul P, Kalayanarooj S, Pulmanausahakul R, Ubol S
Microbiol. Immunol., 2009;53(8):442-50.
Species: Human
Sample Type: Plasma
Authors: Jaiyen Y, Masrinoul P, Kalayanarooj S, Pulmanausahakul R, Ubol S
Microbiol. Immunol., 2009;53(8):442-50.
Species: Human
Sample Type: Plasma
Interleukin-6 is a significant predictor of radiographic knee osteoarthritis: The Chingford Study.
Authors: Livshits G, Zhai G, Hart DJ, Kato BS, Wang H, Williams FM, Spector TD
Arthritis Rheum., 2009;60(7):2037-45.
Species: Human
Sample Type: Serum
Authors: Livshits G, Zhai G, Hart DJ, Kato BS, Wang H, Williams FM, Spector TD
Arthritis Rheum., 2009;60(7):2037-45.
Species: Human
Sample Type: Serum
Age-dependent mobilization of circulating endothelial progenitor cells in infants and young children undergoing cardiac surgery with cardiopulmonary bypass.
Authors: Sun Y, Yi D, Wang Y, Zheng R, Sun G, Wang J, Liu Y, Ren J, Wang Y, Zhang S, Gu C, Pei J
Cytokine, 2009;47(3):206-13.
Species: Human
Sample Type: Plasma
Authors: Sun Y, Yi D, Wang Y, Zheng R, Sun G, Wang J, Liu Y, Ren J, Wang Y, Zhang S, Gu C, Pei J
Cytokine, 2009;47(3):206-13.
Species: Human
Sample Type: Plasma
Acetaldehyde stimulates monocyte adhesion in a P-selectin- and TNFalpha-dependent manner.
Authors: Redmond EM, Morrow D, Kundimi S, Miller-Graziano CL, Cullen JP
Atherosclerosis, 2009;204(2):372-80.
Species: Human
Sample Type: Cell Culture Supernates
Authors: Redmond EM, Morrow D, Kundimi S, Miller-Graziano CL, Cullen JP
Atherosclerosis, 2009;204(2):372-80.
Species: Human
Sample Type: Cell Culture Supernates
Interleukin-18 is a strong predictor of cardiovascular events in elderly men with the metabolic syndrome: synergistic effect of inflammation and hyperglycemia.
Authors: Troseid M, Seljeflot I, Hjerkinn EM, Arnesen H
Diabetes Care, 2009;32(3):486-92.
Species: Human
Sample Type: Serum
Authors: Troseid M, Seljeflot I, Hjerkinn EM, Arnesen H
Diabetes Care, 2009;32(3):486-92.
Species: Human
Sample Type: Serum
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