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iMatrix series | Funakoshi
Cel l culture coating material / substrate of laminin fragment iMatrix series | Funakoshi
Date：March 20 2020Web Page No：81450
A series of recombinant human laminins as various cell culture substrate.
Laminin is one of the extra cellular matrixes (ECM) located in the basement membrane of animals, and play an important role for cell adhesion and proliferation. Laminin is composed of three parts ; alpha, beta, and gamma chain, and 15 types of laminin has been already known.
iMatrix is the purified E8 fragment in α-chain of laminins, which has integrin binding ability.
Depending on cultured cell types, 3 types of iMatrix (-221, -411 and -511) are available as an optimized product.
- iMatrix 221: For cardiomyocytes or skeletal muscule cells culture
- iMatrix 411: For induction of endothelial progenitor cells from iPS cells
iMatrix 221: For cardiomyocytes or skeletal muscule cells culture
iMatrix 221 is a useful cell culture substrate for proliferation and differentiation of cardiomyocytes and skeletal muscule cells.
This is a recombinant human laminin 221 E8 fragment protein which contains the integrin binding site of the laminin 221 molecule.
Video
Can check video of differentiated cardiomyocytes pulsating on iMatrix-221 at:
Product Information
[Date : April 26 2025 00:07]
[Date : April 26 2025 00:07]
iMatrix 411: For induction of endothelial progenitor cells from iPS cells
This is a recombinant human laminin 411 E8 fragment protein which contains the integrin binding site of the laminin 411 molecule.
After culturing on iMatrix-511 and replacing it to iMatrix-411, endothelial progenitor cells are efficiently induced from pluripotent stem cells.
Phenotypes of endothelial cells induced from pluripotent stem cells on iMatrix-411 coated plate.
Acetyl-LDL uptake (Red), CD31 (Green) expression and nuclear stainiing (Blue).
Scale bar : 10 μm
Product Information
[Date : April 26 2025 00:07]
[Date : April 26 2025 00:07]
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