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HOME> Products> Cell Culture> Coating> iMatrix-111

To induce differentiation of human iPS cells into hepatoblast-like cells iMatrix-111

Date：June 24 2026Web Page No：160791

This product is purified to high purity only the E8 region (including integrin binding site) of human laminin 111 protein.
It can be used to induce differentiation of human iPS cells into hepatoblast-like cells (HLCs).

＊The products are for research use only.

iMatrix Lineup
What is laminin 111
Examples of Use
Reference
Product Information

iMatrix Lineup

iMatrix-511 series for feeder-free culture and single-cell passaging of ES/iPS cells
Liquid format (Dilution required)
Liquid format (No dilution required)
iMatrix-411 for efficient induction of endothelial progenitor cells from iPS cells
Liquid format (Dilution required)
iMatrix-221 for purification and maintenance of cardiomyocytes
Liquid format (Dilution required)
iMatrix-111 for differentiation-induction into hepatoblast-like cells from human iPS cells
Liquid format (Dilution required) These are the products introduced in this article.
iMatrix-332 for differentiation-induction into corneal epithelial cells from iPS cells
Liquid format (Dilution required)

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What is laminin 111

Laminin 111 is present in the liver and is known to bind to integrin α7X2β1 and α6β1 proteins, and is thought to be involved in maintaining liver tissue function.

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Examples of Use

Induction of differentiation of human iPS Cells into hepatoblast-like cells (HBCs) and hepatocyte-like cells (HLCs)

※ Laminin 111E8: a fragment of the laminin 111E8 region, is the major component of iMatrix-111
※※ LN-511E8/Laminin 511E8: a fragment of the laminin -511E8 region, is the major component of iMatrix-511

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Reference

Takayama, K., et al., Hepatol. Commun., 1(10):1058-1069 (2017). [PMID：29404442]

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Product Information

[Date : July 04 2026 00:09]

Detail Product Name Product Code Supplier Size Price

iMatrix-111
DatasheetThis may not be the latest data sheet. 892071 MAX 2x175 µg $561

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Description	iMatrix-111 is a recombinant human laminin-111 E8 fragment protein containing the integrin-binding site expressed in CHO-S cells. This product is useful for differentiation of pluripotent stem cells into hepatic progenitor cells, hepatocytes, and neural cells also supports the culture of other cells adhering to laminin-111 such as neural cells.
Storage	4°C,Dark Storage	CAS
Link

iMatrix-111
DatasheetThis may not be the latest data sheet. 892072 MAX 6x175 µg $1,508

Contact

Description	iMatrix-111 is a recombinant human laminin-111 E8 fragment protein containing the integrin-binding site expressed in CHO-S cells. This product is useful for differentiation of pluripotent stem cells into hepatic progenitor cells, hepatocytes, and neural cells also supports the culture of other cells adhering to laminin-111 such as neural cells.
Storage	4°C,Dark Storage	CAS
Link

[Date : July 04 2026 00:09]

iMatrix-111

DatasheetThis may not be the latest data sheet.

Product Code: 892071
Supplier: MAX
Size: 2x175µg
Price: $561

Description	iMatrix-111 is a recombinant human laminin-111 E8 fragment protein containing the integrin-binding site expressed in CHO-S cells. This product is useful for differentiation of pluripotent stem cells into hepatic progenitor cells, hepatocytes, and neural cells also supports the culture of other cells adhering to laminin-111 such as neural cells.
Storage	4°C,Dark Storage	CAS
Link

Contact

iMatrix-111

DatasheetThis may not be the latest data sheet.

Product Code: 892072
Supplier: MAX
Size: 6x175µg
Price: $1,508

Description	iMatrix-111 is a recombinant human laminin-111 E8 fragment protein containing the integrin-binding site expressed in CHO-S cells. This product is useful for differentiation of pluripotent stem cells into hepatic progenitor cells, hepatocytes, and neural cells also supports the culture of other cells adhering to laminin-111 such as neural cells.
Storage	4°C,Dark Storage	CAS
Link

Contact

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CONTACT

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