Sugar surfactant harboring functions of protein extraction and solubilization IMCTA-C14 (Trifluoroacetate)
Date：July 01 2025Web Page No：520089
IMCTA-C14 is N-tetradecyl derivative from 4-trehalosamine and functions similarly to a sugar surfactant with a complex of a sugar as a hydrophilic group and long chain aliphatic hydrocarbon. This compound is stable against trehalases in mammalian and was not observed hydrolysis by porcine one.1) In addition, it showed high efficiency of protein extraction and solubilization without denaturing proteins.1)
*4-Trehalosamine and its analogue, lentztrehalose are also available. Click here!
* This product is for research use only.
Structure of IMCTA-C14 (trifluoroacetate) (#15613)
- Specification
- Application Note
- Reference
- Product Information
- Related Products: 4-Trehalosamine / Lentztrehalose
Specification
| Molecular Formula | C26H51NO10･CF3COOH |
|---|---|
| Molecular Weight | 651.714 |
| Purity | >90% (qNMR) |
| Solubility | Soluble in DMSO, MeOH, and H2O |
Application Note
- Unlike trehalose, IMCTA-C14 was not hydrolyzed by incubation with a mammalian trehalase.1)
- This trehalose analogue did not show protein denaturing activity.
- IMCTA-C14 showed strong activity of protein extraction similar to IMCTA-C12, and IMCTA-C13 harboring the length of carbon side chains, 12 and 13, respectively.
Reference
- Wada, S., et al., Adv. Bio., 6 (6), e2101309 (2022). [PMID:35297567]
Product Information
[Date : July 15 2025 00:07]
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IMCTA-C14 (trifluoroacetate), High Protein Extraction and Solubilization Activities DatasheetThis may not be the latest data sheet. |
15613 | IMCInstitute of Microbial Chemistry | 5 mg | $500 | |||||||||||||||||||||||||||||||
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[Date : July 15 2025 00:07]
IMCTA-C14 (trifluoroacetate), High Protein Extraction and Solubilization Activities
DatasheetThis may not be the latest data sheet.
- Product Code: 15613
- Supplier: IMC
- Size: 5mg
- Price: $500
| Description |
M.W.: 651.714 Purity : >90% (qNMR) Molecular Formula : C26H51NO10・CF3COOH Solubility : Soluble in MeOH, H2O, and DMSO IMCTA-C14 is N-tetradecyl derivative from 4-Trehalosamine, and showed high efficiency of protein extraction and solubilization without denaturing proteins. It was reported that this compound is stable against trehalases in mammalian and was not observed hydrolysis by porcine one. |
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| Storage | -20°C | CAS | |
| Link |
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Related Products: 4-Trehalosamine / Lentztrehalose
4-Trehalosamine
4-Trehalosamine is a trehalose analogue which is expected to have similar functions of it and was known as biologically stable against digestion by mammalian trehalase. Furthermore, its functions which trehalose does not have is pH buffering action at neutral pH stronger than Tris which is a well-known buffer solution. Therefore, 4-trehalosamine might be expected to be more suitable for versatile applications than trehalose because of a moisturizing protectant with pH buffering action.
* See dtails of 4-Trehalosamine, click here!
Structure of 4-Trehalosamine (#15612)
Lentztrehalose
Lentztrehalose A, B, C are trehalose analogues isolated from the soilid-state culture of Lentzea sp. ML457-mF8. Unlike trehalose, these lentztrehalose are stable to porcine kidney trehalase and not broken down by various microorganisms that metabolize trehalose.
* See details of Lentztrehalose, click here!
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