抗Human CCR3 Fluorescein抗体(Anti-Human CCR3 Fluorescein antibody)

• 価格
• Product Details
• Applications and Data
• Related Product & Information
• Citations

価格

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Product Details

Species Reactivity	Human
Label	Fluorescein
Immunogen	Y3 rat myeloid cell line transfected with human CCR3Accession # P51677
Source	Monoclonal Rat IgG2A Clone # 61828
Purification	Protein A or G purified from hybridoma culture supernatant
Specificity	Detects human CCR3 transfectants in flow cytometry. In flow cytometry, no cross-reactivity with CCR1, CCR2, CCR5, and CCR6 transfectants or the parental cell line is observed. Detects CCR3 on peripheral blood eosinophils.

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Applications and Data

	Recommended Concentration	Sample
Flow Cytometry	10 µL/106 cells	See below

Flow Cytometry

Detection of CCR3 in Human Blood Granulocytes by Flow Cytometry. Human peripheral blood granulocytes were stained with Mouse Anti-Human Integrin  alpha 4/CD49d APC‑conjugated Monoclonal Antibody (Catalog # FAB1354A) and either (A) Rat Anti-Human CCR3 Fluorescein‑conjugated Monoclonal Antibody (Catalog # FAB155F) or (B) Rat IgG2A Fluorescein Isotype Control (Catalog # IC006F). View our protocol for Staining Membrane-associated Proteins.

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Related Product & Information

Entrez Gene IDs	1232 (Human); 12771 (Mouse); 117027 (Rat); 448802 (Canine)
Background	CCR3
background_content	Background: CCR3 CCR3 is a G protein-linked seven transmembrane chemokine receptor that preferentially binds eotaxin and eotaxin-2.

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Citations

1. Detection of Primary T Cell Responses to Drugs and Chemicals in HLA-Typed Volunteers: Implications for the Prediction of Drug Immunogenicity
   Authors: Lee Faulkner
   Toxicol. Sci, 2016;154(2):416-429.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


2. Chemokine receptor expression on allergen-specific T cells in asthma and allergic bronchopulmonary aspergillosis.
   Authors: Garcia G, Humbert M, Capel F, Rimaniol AC, Escourrou P, Emilie D, Godot V
   Allergy, 2007;62(2):170-7.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


3. CC chemokine receptor 5 and CXC chemokine receptor 6 expression by lung CD8+ cells correlates with chronic obstructive pulmonary disease severity.
   Authors: Freeman CM, Curtis JL, Chensue SW
   Am. J. Pathol., 2007;171(3):767-76.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


4. Modulation of eotaxin-3 (CCL26) in alveolar type II epithelial cells.
   Authors: Abonyo BO, Lebby KD, Tonry JH, Ahmad M, Heiman AS
   Cytokine, 2006;36(5):237-44.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


5. Anti-IL-5 (mepolizumab) therapy for eosinophilic esophagitis.
   Authors: Stein ML, Collins MH, Villanueva JM, Kushner JP, Putnam PE, Buckmeier BK, Filipovich AH, Assa'ad AH, Rothenberg ME
   J. Allergy Clin. Immunol., 2006;118(6):1312-9.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


6. Modulation of GM-CSF release by enantiomers of beta-agonists in human airway smooth muscle.
   Authors: Ameredes BT, Calhoun WJ
   J. Allergy Clin. Immunol., 2005;116(1):65-72.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


7. Aberration of CCR7 CD8 memory T cells from patients with systemic lupus erythematosus: an inducer of T helper type 2 bias of CD4 T cells.
   Authors: Sen Y, Chunsong H, Baojun H, Linjie Z, Qun L, San J, Qiuping Z, Junyan L, Zhang X, Jinquan T
   Immunology, 2004;112(2):274-89.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


8. Phenotypic and functional analysis of T cells homing into the CSF of subjects with inflammatory diseases of the CNS.
   Authors: Giunti D, Borsellino G, Benelli R, Marchese M, Capello E, Valle MT, Pedemonte E, Noonan D, Albini A, Bernardi G, Mancardi GL, Battistini L, Uccelli A
   J. Leukoc. Biol., 2003;73(5):584-90.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


9. Regulation of CCR5 expression and MIP-1alpha production in CD4+ T cells from patients with rheumatoid arthritis.
   Authors: Wang CR, Liu MF
   Clin. Exp. Immunol., 2003;132(2):371-8.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow

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