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A cytosine nucleoside compound harboring acaricidal and broad antibacterial activities Bagougeramine A (Formate)

Date:October 24 2025Web Page No:520102

Bagougeramine A is a cytosine nucleoside compound and was isolated from culture filtrate of Bacillus circulans which was discovered in soil. This compound exhibited strong acaricidal activity against the two spotted spier mite (Tetranychus urticae) and had broad antimicrobial activity against bacteria and fungi.1,2)
On the other hand, gougerotin which was discovered as a natural compound harboring antibacterial activity from Streptomyces gougerotii had similar structure of bagougeramine A and was also reported that the compound inhibited protein synthesis.3,4)
* This product is for research use only.


Bagougeramine A構造

Bagougeramine A (#18206)

Gougerotin構造

Gougerotin

Structure of Bagougeramine A and Gougerotin


Specification

CAS#104840-35-9 (This CAS# is for free salt form, shown as a reference.)*
Molecular FormulaC17H28N10O7・2HCO2H (for the formate salt form)
Molecular Weight 576.524 (for the formate salt form)
Purity>98% (HPLC)
SolubilitySoluble in H2O
Slightly soluble in DMSO
Insoluble in MeOH
* This product is supplied as the formate salt form of which CAS# has not been given yet.

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Application Note

  • In comparison to dicofol harboring acaricidal activity, bagougeramine A exhibited strong activity against the two-spotted spider mite.1)
  • This compound showed antibacterial activity against gram-positive bacteria, gram-negative bacteria, and some fungal species such as Pellicularia frlanrentosa f. sp. Sasakii which was known as a plant pathogen.1)
  • It was considered that toxicity of bagougeramine A is low because oral administration of this compound (100 mg/kg) to mice did not exhibit acute toxicity. 1)

* Biological activity of the product was not verified. The values shown above were cited from the references.


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Reference

  1. Takahashi A., et al., J. Antibiotics, 39 (8), 1033~1040 (1986). [PMID:3759653]
  2. Takahashi A., et al., J. Antibiotics, 39 (8), 1041~1046 (1986). [PMID:3759654]
  3. Kanzaki T., et al., J. Antibiotics, 15 (2), 93~97 (1962). [DOI:10.11554/antibioticsa.15.2_93]
  4. Clark, J. M. Jr., et al., Biochimica et Biophysica Acta, Specialized Section on Nucleic Acids and Related Subjects, 76 (4), 636~638 (1963). [DOI:10.1016/0926-6550(63)90092-6]

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Product Information

[Date : October 25 2025 00:07]

Detail Product Name Product Code Supplier Size Price
Bagougeramine A Formate <Acaricidal>
DatasheetThis may not be the latest data sheet.
18206 IMCInstitute of Microbial Chemistry 1 mg $500

Description M.W.: 576.524 Purity : >98% (HPLC) Molecular Formula : C17H28N10O7・2HCO2H (formate salt form) Solubility : Soluble in H2O Slightly soluble in DMSO, Insoluble in MeOH Bagougeramine A exhibited acaricidal activity against the two spotted spier mite (Tetranychus urticae) and had broad antimicrobial activity against bacteria and fungi. This product is supplied as the formate from.
Storage -20°C CAS 104840-35-9 (salt free form)
Link

[Date : October 25 2025 00:07]

Bagougeramine A Formate <Acaricidal>


  • Product Code: 18206
  • Supplier: IMC
  • Size: 1mg
  • Price: $500

Description M.W.: 576.524 Purity : >98% (HPLC) Molecular Formula : C17H28N10O7・2HCO2H (formate salt form) Solubility : Soluble in H2O Slightly soluble in DMSO, Insoluble in MeOH Bagougeramine A exhibited acaricidal activity against the two spotted spier mite (Tetranychus urticae) and had broad antimicrobial activity against bacteria and fungi. This product is supplied as the formate from.
Storage -20°C CAS 104840-35-9 (salt free form)
Link


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