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Institute of Microbial Chemistry (1 items)

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[Date : May 19 2025 00:06]

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Heliquinomycin, DNA Helicase Inhibitor
DatasheetThis may not be the latest data sheet. 10665 IMCInstitute of Microbial Chemistry 1 mg $500

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Description	M.W.: 698.5811 Purity : > 80％ (HPLC) Molecular Formula : C33H30O17 Solubility : Soluble in EtOAc, EtOH, and DMSO, Insoluble in H2O, and Hexane. Heliquinomycin is a natural product derived from actinomycetes and inhibits DNA helicase. This compound inhibits DNA helicase from HeLa cell (Ki＝6.8 mM). In addition, it inhibits growth of human tumor cell lines such as HeLa S3, KB, LS180, K562, and HL60 (IC50＝0.96～2.8 μg/ml). In cell culture, this compound also inhibits both DNA and RNA synthesis but do not inhibit protein synthesis. It was reported that HeLa S3 growth was arrested at G2/M phase by Heliquinomycin treatment.
Storage	-20°C	CAS	178182-49-5
Link	Heliquinomycin Bioactive Compounds Natural compound Product List

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[Date : May 19 2025 00:06]

Heliquinomycin, DNA Helicase Inhibitor

DatasheetThis may not be the latest data sheet.

Product Code: 10665
Supplier: IMC
Size: 1mg
Price: $500

Description	M.W.: 698.5811 Purity : > 80％ (HPLC) Molecular Formula : C33H30O17 Solubility : Soluble in EtOAc, EtOH, and DMSO, Insoluble in H2O, and Hexane. Heliquinomycin is a natural product derived from actinomycetes and inhibits DNA helicase. This compound inhibits DNA helicase from HeLa cell (Ki＝6.8 mM). In addition, it inhibits growth of human tumor cell lines such as HeLa S3, KB, LS180, K562, and HL60 (IC50＝0.96～2.8 μg/ml). In cell culture, this compound also inhibits both DNA and RNA synthesis but do not inhibit protein synthesis. It was reported that HeLa S3 growth was arrested at G2/M phase by Heliquinomycin treatment.
Storage	-20°C	CAS	178182-49-5
Link	Heliquinomycin Bioactive Compounds Natural compound Product List

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