抗Human EG-VEGF/PK1抗体(Anti-Human EG-VEGF/PK1 antibody)
掲載日情報：2021/01/28 現在Webページ番号：34581
Human EG-VEGF/PK1に対する抗体(Anti-Human EG-VEGF/PK1 )です。
※ 本製品は研究用です。研究用以外には使用できません。
追加しました。
- 価格
- Product Details
- Applications and Data
- References
- Related Research Areas
- Related Product & Information
価格
[在庫・価格 ：2024年05月18日 10時15分現在]
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Anti-Human EG-VEGF/PK1 MAb (Clone 188608) (500 UG) |
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Anti-Human EG-VEGF/PK1 MAb (Clone 188608) |
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[在庫・価格 ：2024年05月18日 10時15分現在]
Anti-Human EG-VEGF/PK1 MAb (Clone 188608) (500 UG)
文献数： 0
- 商品コード：MAB12091
- メーカー：RSD
- 包装：500μg
- 価格：¥121,000
- 在庫：無(未発注)
- 納期：10日程度 ※※ 表示されている納期は弊社に在庫がなく、取り寄せた場合の目安納期となります。
- 法規制等：
| 説明文 |
マッチドペア：Human EG-VEGF/PK1 サンドイッチELISAの補足用抗体として利用可能，検出用抗体として#BAF1209，スタンダードとして#1209-EV-025を用いる。 別名：EGVEGF クローン：188608 Genbank No： 84432 Protein Accession No： P58294 |
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| 別包装品 | 別包装品あり | ||||||
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| 保存条件 | -20℃ | 法規備考 | |||||
| 抗原種 | Human | 免疫動物 | Mouse | ||||
| 交差性 | Human | 適用 | ELISA | ||||
| 標識 | Unlabeled | 性状 | Protein A/G Affinity Purified | ||||
| 吸収処理 | クラス | IgG | |||||
| クロナリティ | Monoclonal | フォーマット | |||||
| 掲載カタログ |
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| 関連記事 |
R&D Systems(R&Dシステムズ)社 ELISA用ペア抗体を使用したELISA 構築ガイド |
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Anti-Human EG-VEGF/PK1 MAb (Clone 188608)
文献数： 0
- 商品コード：MAB12091-SP
- メーカー：RSD
- 包装：25μg
- 価格：¥30,000
- 在庫：無(未発注)
- 納期：2～3週間 ※※ 表示されている納期は弊社に在庫がなく、取り寄せた場合の目安納期となります。
- 法規制等：
| 説明文 |
※受注発注品。形状：溶液または凍結乾燥 別名：EGVEGF クローン：188608 Genbank No： 84432 Protein Accession No： P58294 |
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| 別包装品 | 別包装品あり | ||||||
| 法規制等 | |||||||
| 保存条件 | 法規備考 | ||||||
| 抗原種 | 免疫動物 | Mouse | |||||
| 交差性 | Human | 適用 | ELISA | ||||
| 標識 | Unlabeled | 性状 | Protein A/G Affinity Purified | ||||
| 吸収処理 | クラス | IgG | |||||
| クロナリティ | Monoclonal | フォーマット | |||||
| 掲載カタログ |
|
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| 製品記事 | |||||||
| 関連記事 |
R&D Systems(R&Dシステムズ)社 ELISA用ペア抗体を使用したELISA 構築ガイド |
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Product Details
| Species Reactivity | Human |
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| Label | Unconjugated |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant human EG‑VEGF/PK1Ala20-Phe105Accession # P58294 |
| Source | Monoclonal Mouse IgG1 Clone # 188608 |
| Purification | Protein A or G purified from hybridoma culture supernatant |
| Specificity | Detects human EG‑VEGF/PK1 in direct ELISAs and Western blots. |
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Applications and Data
| Recommended Concentration | Sample | |
| Human EG-VEGF/PK1 Sandwich Immunoassay | Reagent | |
| ELISA Capture (Matched Antibody Pair) | 2-8 µg/mL | Human EG‑VEGF/PK1 Antibody (Catalog #MAB12091 ) |
| ELISA Detection (Matched Antibody Pair) | 0.1-0.4 µg/mL | Human EG‑VEGF/PK1 Biotinylated Antibody (Catalog #BAF1209 ) |
| ELISA Standard | Recombinant Human EG-VEGF/PK1 Protein (Catalog #1209-EV ) | |
| Please Note: Optimal dilutions should be determined by each laboratory for each application.General Protocolsare available in the Technical Information section on our website. | Preparation and Storage | |
| Reconstitution | Reconstitute at 0.5 mg/mL in sterile PBS. | Reconstitution Buffer Available |
| Shipping | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C | |
| Stability & Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. | |
| 1 month, 2 to 8 °C under sterile conditions after reconstitution. | ||
| 6 months, -20 to -70 °C under sterile conditions after reconstitution. | ||
| Background: EG-VEGF/PK1 | Endocrine gland-derived vascular endothelial growth factor (EG-VEGF), also called prokineticin 1 (PK1), is a member of the prokineticin family of secreted proteins that share a common structural motif containing ten conserved cysteine residues that form five pairs of disulfide bonds (1, 2). Members of this family include the mammalian EG-VEGF/PK1 and PK2, as well as the venom protein A (VPRA) from the venom of black mamba snake and the frog Bombina variegata, Bv8 (1). Human EG-VEGF precursor is a 105 amino acid (aa) residue protein with a 19 aa signal peptide that is cleaved to yield a 86 aa mature protein (1, 2). EG-VEGF is expressed in multiple tissues including the gastrointestinal (GI) tract and steroidogenic glands (testis, ovary, placenta and adrenal glands). EG-VEGF has been shown to potently stimulate the contraction of GI smooth muscle. In addition, EG-VEGF is a tissue-specific angiogenic factor that exhibits biological activities similar to that of VEGF on select cells. It induces the proliferation, migration, and fenestration in cultured endocrine gland-derived capillary endothelial cells. EG-VEGF binds to and activates two closely related G protein-coupled receptors, EG-VEGF/PK1-R1 and EG-VEGF/PK2-R2 (3, 4). Activation of the receptors leads to stimulation of phosphoinositide turnover and activation of p44/p42 MAP kinase signaling pathways. |
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References
| Li, M. et al. (2001) Mol. Pharmacol. 59:692. | |
| LeCouter, J. et al. (2001) Nature 412:877. | |
| Lin, D. et al. (2002) J. Biol. Chem. 277:19276. | |
| Masuda, Y. et al. (2002) Biochem. Biophys. Res. Commun. 293:396. | |
| Long Name: | Endocrine Gland-derived Vascular Endothelial Growth Factor |
| Entrez Gene IDs: | 84432 (Human); 246691 (Mouse); 192205 (Rat) |
| Alternate Names: | EGVEGF; EG-VEGF; EGVEGFblack mamba toxin-related protein; Endocrine-gland-derived vascular endothelial growth factor; Mambakine; PK1mambakine; PRK1prokineticin-1; PROK1; Prokineticin 1 |
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Related Research Areas
| Digestive Peptide Hormones and Regulators |
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Related Product & Information
| Background | EG-VEGF/PK1 |
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| background_content | Background: EG-VEGF/PK1 Endocrine gland-derived vascular endothelial growth factor (EG-VEGF), also called prokineticin 1 (PK1), is a member of the prokineticin family of secreted proteins that share a common structural motif containing ten conserved cysteine residues that form five pairs of disulfide bonds (1, 2). Members of this family include the mammalian EG-VEGF/PK1 and PK2, as well as the venom protein A (VPRA) from the venom of black mamba snake and the frog Bombina variegata, Bv8 (1). Human EG-VEGF precursor is a 105 amino acid (aa) residue protein with a 19 aa signal peptide that is cleaved to yield a 86 aa mature protein (1, 2). EG-VEGF is expressed in multiple tissues including the gastrointestinal (GI) tract and steroidogenic glands (testis, ovary, placenta and adrenal glands). EG-VEGF has been shown to potently stimulate the contraction of GI smooth muscle. In addition, EG-VEGF is a tissue-specific angiogenic factor that exhibits biological activities similar to that of VEGF on select cells. It induces the proliferation, migration, and fenestration in cultured endocrine gland-derived capillary endothelial cells. EG-VEGF binds to and activates two closely related G protein-coupled receptors, EG-VEGF/PK1-R1 and EG-VEGF/PK2-R2 (3, 4). Activation of the receptors leads to stimulation of phosphoinositide turnover and activation of p44/p42 MAP kinase signaling pathways. |
追加しました。
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