抗Mouse CCR3 Phycoerythrin抗体(Anti-Mouse CCR3 Phycoerythrin antibody)

• 価格
• Product Details
• Applications and Data
• Related Product & Information
• Citations

価格

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Product Details

Species Reactivity	Mouse
Label	Phycoerythrin
Immunogen	Y3 rat myeloid cell line transfected with mouse CCR3Met1-Phe359Accession # P51678
Source	Monoclonal Rat IgG2A Clone # 83101
Purification	Protein A or G purified from hybridoma culture supernatant
Specificity	Detects mouse CCR3. Specifically stains mouse CCR3 transfectants but not the parental cell lines. Does not cross‑react with Y3 cells transfected with human CCR3.

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Applications and Data

	Recommended Concentration	Sample
Flow Cytometry	0.25-1 µg/106 cells	See below

Flow Cytometry

Detection of CCR3 in Mouse Splenocytes by Flow Cytometry. Mousesplenocytes were stained with Rat Anti-Mouse CCR3 PE‑conjugated Monoclonal Antibody (Catalog # FAB729P) and Rat Anti-Mouse Gr‑1/Ly‑6G Fluoresein‑conjugated Monoclonal Antibody (Catalog # FAB1037F). Quadrant markers were set based on control antibody staining (Catalog # IC006P). View our protocol for Staining Membrane-associated Proteins.

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Related Product & Information

Entrez Gene IDs	1232 (Human); 12771 (Mouse); 117027 (Rat); 448802 (Canine)
Background	CCR3
background_content	Background: CCR3 CCR3 is a G protein-linked seven transmembrane receptor that is activated by several different chemokines. It is expressed on subsets of granulocytes, monocytes, T cells and epithelial cells.

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Citations

1. A prominent air pollutant, Indeno[1,2,3-cd]pyrene, enhances allergic lung inflammation via aryl hydrocarbon receptor
   Authors: TH Wong, CL Lee, HH Su, CL Lee, CC Wu, CC Wang, CC Sheu, RS Lai, SY Leung, CC Lin, YF Wei, CJ Wang, YC Lin, HL Chen, MS Huang, JH Yen, SK Huang, JL Suen
   Sci Rep, 2018;8(1):5198.
   Species: Mouse
   Sample Type: BALF
   Application: Flow


2. Self-renewal and phenotypic conversion are the main physiological responses of macrophages to the endogenous estrogen surge
   Authors: G Pepe, D Braga, TA Renzi, A Villa, C Bolego, F D'Avila, C Barlassina, A Maggi, M Locati, E Vegeto
   Sci Rep, 2017;7(0):44270.
   Species: Mouse
   Sample Type: Whole Cells
   Application: Flow


3. CCL2/CCR2 Regulates the Tumor Microenvironment in HER-2/neu-Driven Mammary Carcinomas in Mice
   PLoS ONE, 2016;11(11):e0165595.
   Species: Mouse
   Sample Type: Whole Cells
   Application: Flow


4. Over-expression of the LTC4 synthase gene in mice reproduces human aspirin-induced asthma.
   Authors: Hirata H, Arima M, Fukushima Y, Honda K, Sugiyama K, Tokuhisa T, Fukuda T
   Clin. Exp. Allergy, 2011;41(8):1133-42.
   Species: Mouse
   Sample Type: Whole Cells
   Application: Flow


5. The TLR7 ligand 9-benzyl-2-butoxy-8-hydroxy adenine inhibits IL-17 response by eliciting IL-10 and IL-10-inducing cytokines.
   Authors: Vultaggio A, Nencini F, Pratesi S, Maggi L, Guarna A, Annunziato F, Romagnani S, Parronchi P, Maggi E
   J. Immunol., 2011;186(8):4707-15.
   Species: Mouse
   Sample Type: Whole Cells
   Application: Flow


6. Impaired basophil induction leads to an age-dependent innate defect in type 2 immunity during helminth infection in mice.
   Authors: Nel HJ, Hams E, Saunders SP
   J. Immunol., 2011;186(8):4631-9.
   Species: Mouse
   Sample Type: Whole Cells
   Application: Flow


7. Sensitization by intratracheally injected dendritic cells is independent of antigen presentation by host antigen-presenting cells.
   Authors: Kuipers H, Soullie T, Hammad H, Willart M, Kool M, Hijdra D, Hoogsteden HC, Lambrecht BN
   J. Leukoc. Biol., 2009;85(1):64-70.
   Species: Mouse
   Sample Type: BALF
   Application: Flow


8. Anti-Siglec-F antibody reduces allergen-induced eosinophilic inflammation and airway remodeling.
   Authors: Song DJ, Cho JY, Lee SY, Miller M, Rosenthal P, Soroosh P, Croft M, Zhang M, Varki A, Broide DH
   J. Immunol., 2009;183(8):5333-41.
   Species: Mouse
   Sample Type: Whole Cells
   Application: Flow


9. Ablation of type I hypersensitivity in experimental allergic conjunctivitis by eotaxin-1/CCR3 blockade.
   Authors: Miyazaki D, Nakamura T, Ohbayashi M, Kuo CH, Komatsu N, Yakura K, Tominaga T, Inoue Y, Higashi H, Murata M, Takeda S, Fukushima A, Liu FT, Rothenberg ME, Ono SJ
   Int. Immunol., 2009;21(2):187-201.
   Species: Mouse
   Sample Type: Whole Cells
   Application: Flow


10. Treatment with anti-CC chemokine receptor 3 monoclonal antibody or dexamethasone inhibits the migration and differentiation of bone marrow CD34 progenitor cells in an allergic mouse model.
    Authors: Ben S, Li X, Xu F, Xu W, Li W, Wu Z, Huang H, Shi H, Shen H
    Allergy, 2008;63(9):1164-76.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Flow

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