抗IL-17 Receptor抗体(Anti-IL-17 Receptor, Human, Goat-Poly, Biotin antibody)
掲載日情報：2021/01/28 現在Webページ番号：29824
IL-17 Receptorに対する抗体(Anti-IL-17 Receptor, Human, Goat-Poly, Biotin )です。
※ 本製品は研究用です。研究用以外には使用できません。
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- 価格
- Product Details
- Applications and Data
- References
- Related Research Areas
- Related Product & Information
- Citations
価格
[在庫・価格 ：2025年04月26日 20時55分現在]
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[在庫・価格 ：2025年04月26日 20時55分現在]
Anti-IL-17 Receptor, Human, Goat-Poly, Biotin
文献数： 2
- 商品コード：BAF177
- メーカー：RSD
- 包装：50μg
- 価格：¥113,000
- 在庫：無(未発注)
- 納期：10日程度 ※※ 表示されている納期は弊社に在庫がなく、取り寄せた場合の目安納期となります。
- 法規制等：
| 説明文 | マッチドペア：Human IL-17 RA/IL-17 R サンドイッチELISAの検出用抗体として利用可能，補足用抗体として#MAB1771，スタンダードとして#177-IR-100を用いる。 別名：CD217 Genbank No： 23765 Protein Accession No： Q96F46 |
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| 法規制等 | |||
| 保存条件 | -20℃ | 法規備考 | |
| 抗原種 | Human | 免疫動物 | Goat |
| 交差性 | Human | 適用 | ELISA,Western Blot |
| 標識 | Biotin | 性状 | Antigen Affinity Purified |
| 吸収処理 | クラス | IgG | |
| クロナリティ | Polyclonal | フォーマット | |
| 掲載カタログ |
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| 製品記事 | Helper T Cells Marker Antibodies |
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| 関連記事 | R&D Systems(R&Dシステムズ)社 ELISA用ペア抗体を使用したELISA 構築ガイド |
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Product Details
| Species Reactivity | Human |
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| Label | Biotin |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant human IL‑17 RA/IL‑17 RLeu33-Trp320Accession # Q96F46 |
| Source | Polyclonal Goat IgG |
| Purification | Antigen Affinity-purified |
| Specificity | Detects human IL‑17 RA/IL‑17 R in ELISAs and Western blots. In sandwich immunoassays, less than 1% cross-reactivity with recombinant human IL‑17 RB is observed. |
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Applications and Data
| Recommended Concentration | Sample | |
| Western Blot | 0.1 µg/mL | Recombinant Human IL‑17 RA/IL‑17 R Fc Chimera (Catalog # 177-IR) |
| Human IL-17 RA/IL-17 R Sandwich Immunoassay | Reagent | |
| ELISA Capture (Matched Antibody Pair) | 2-8 µg/mL | Human IL‑17 RA/IL‑17 R Antibody (Catalog #MAB1771 ) |
| ELISA Detection (Matched Antibody Pair) | 0.1-0.4 µg/mL | Human IL‑17 RA/IL‑17 R Biotinylated Antibody (Catalog #BAF177 ) |
| ELISA Standard | Recombinant Human IL-17 RA/IL-17 R Fc Chimera Protein, CF (Catalog #177-IR ) | |
| Please Note: Optimal dilutions should be determined by each laboratory for each application.General Protocolsare available in the Technical Information section on our website. | Preparation and Storage | |
| Reconstitution | Reconstitute at 0.2 mg/mL in sterile PBS. | Reconstitution Buffer Available |
| Shipping | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. | |
| Stability & Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. | |
| 1 month, 2 to 8 °C under sterile conditions after reconstitution. | ||
| 6 months, -20 to -70 °C under sterile conditions after reconstitution. | ||
| Background: IL-17 RA/IL-17 R | Interleukin 17 (also known as CTLA-8) is a T cell-expressed pleotropic cytokine. IL-17 binds to IL-17 receptor (IL-17 RA/IL-17 R) which shares no homology with any known family of receptors. While the expression of IL-17 is restricted to activated T cells, the IL-IL-17 RA/IL-17 R mRNA exhibits a broad tissue distribution, and has been detected in virtually all cells and tissues tested. The human IL-17 RA/IL-17 R gene was localized to chromosome 22. Human IL-17 RA/IL-17 R is an 866 amino acid (aa) type I membrane glycoprotein with a 293 aa extracellular domain, a 21 aa carboxy-proximal transmembrane domain, and a 525 aa cytoplasmic tail. The aa sequence of human IL‑17 R is 69% identical to the mouse IL-17 RA/IL-17 R. The signaling events of IL-17 includes activation of NF-kappa B and JNK, and require TNF receptor-associated factors 6 (TRAF6) in the signaling pathway (1, 2). |
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References
| Yao, Z. et al. (1997) Cytokine 9:794. | |
| Schwander, R. et al. (2000) J. Exp. Med. 191:1233. | |
| Long Name: | Interleukin 17 Receptor |
| Entrez Gene IDs: | 23765 (Human); 16172 (Mouse); 312679 (Rat) |
| Alternate Names: | CD217 antigen; CD217; Cdw217; CDw217interleukin 17 receptor; hIL-17R; IL-17 R; IL-17 RA; IL-17 receptor A; IL17RA; IL-17RA; IL-17RAMGC10262; IL17Rinterleukin-17 receptor A; interleukin 17 receptor A |
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Related Research Areas
| Cytokines and Receptors in Tfh Cell Differentiation and Function | ||
| IL-17 Family | ||
| Multiple Sclerosis and Myelin Related Molecules | ||
| Th17 Cells | ||
| Th2 Cells | ||
| Th9 Cells | ||
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Related Product & Information
| Background | IL-17 RA/IL-17 R |
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| background_content | Background: IL-17 RA/IL-17 R Interleukin 17 (also known as CTLA-8) is a T cell-expressed pleotropic cytokine. IL-17 binds to IL-17 receptor (IL-17 RA/IL-17 R) which shares no homology with any known family of receptors. While the expression of IL-17 is restricted to activated T cells, the IL-IL-17 RA/IL-17 R mRNA exhibits a broad tissue distribution, and has been detected in virtually all cells and tissues tested. The human IL-17 RA/IL-17 R gene was localized to chromosome 22. Human IL-17 RA/IL-17 R is an 866 amino acid (aa) type I membrane glycoprotein with a 293 aa extracellular domain, a 21 aa carboxy-proximal transmembrane domain, and a 525 aa cytoplasmic tail. The aa sequence of human IL‑17 R is 69% identical to the mouse IL-17 RA/IL-17 R. The signaling events of IL-17 includes activation of NF-kappa B and JNK, and require TNF receptor-associated factors 6 (TRAF6) in the signaling pathway (1, 2). |
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Citations
- Expression and activity of IL-17 in cutaneous T-cell lymphomas (mycosis fungoides and Sezary syndrome).
Authors: Ciree A, Michel L, Camilleri-Broet S, Jean Louis F, Oster M, Flageul B, Senet P, Fossiez F, Fridman WH, Tartour E
Int. J. Cancer, 2004;112(1):113-20.
Species: Human
Sample Type: Whole Cells
Application: Flow - Expression and activity of IL-17 in cutaneous T-cell lymphomas (mycosis fungoides and Sezary syndrome).
Authors: Ciree A, Michel L, Camilleri-Broet S, Jean Louis F, Oster M, Flageul B, Senet P, Fossiez F, Fridman WH, Tartour E
Int. J. Cancer, 2004;112(1):113-20.
Species: Human
Sample Type: Whole Cells
Application: Flow
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