抗Human CCR3 Phycoerythrin抗体(Anti-Human CCR3 Phycoerythrin antibody)

• 価格
• Product Details
• Applications and Data
• Related Product & Information
• Citations

価格

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Product Details

Species Reactivity	Human
Label	Phycoerythrin
Immunogen	Y3 rat myeloid cell line transfected with human CCR3Accession # P51677
Source	Monoclonal Rat IgG2A Clone # 61828
Purification	Protein A or G purified from hybridoma culture supernatant
Specificity	Detects human CCR3 transfectants in flow cytometry. In flow cytometry, no cross-reactivity with CCR1, CCR2, CCR5, and CCR6 transfectants or the parental cell line is observed. Detects CCR3 on peripheral blood eosinophils.

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Applications and Data

	Recommended Concentration	Sample
Flow Cytometry	10 µL/106 cells	See below

Flow Cytometry

Detection of CCR3 in Human Blood Granulocytes by Flow Cytometry. Human peripheral blood granulocytes were stained with Mouse Anti-Human Integrin  alpha 4/CD49d APC‑conjugated Monoclonal Antibody (Catalog # FAB1354A) and either (A) Rat Anti-Human CCR3 PE‑conjugated Monoclonal Antibody (Catalog # FAB155P) or (B) Rat IgG2A Phycoerythrin Isotype Control (Catalog # IC006P). View our protocol for Staining Membrane-associated Proteins.

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Related Product & Information

Entrez Gene IDs	1232 (Human); 12771 (Mouse); 117027 (Rat); 448802 (Canine)
Background	CCR3
background_content	Background: CCR3 CCR3 is a G protein-linked seven transmembrane chemokine receptor that preferentially binds eotaxin and eotaxin-2.

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Citations

1. Distinct roles for CCR4 and CXCR3 in the recruitment and positioning of regulatory T cells in the inflamed human liver.
   Authors: Oo YH, Weston CJ, Lalor PF, Curbishley SM, Withers DR, Reynolds GM, Shetty S, Harki J, Shaw JC, Eksteen B, Hubscher SG, Walker LS, Adams DH
   J. Immunol., 2010;184(6):2886-98.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


2. The Lupane-type Triterpene 30-Oxo-calenduladiol Is a CCR5 Antagonist with Anti-HIV-1 and Anti-chemotactic Activities.
   Authors: Barroso-Gonzalez J, El Jaber-Vazdekis N, Garcia-Exposito L, Machado JD, Zarate R, Ravelo AG, Estevez-Braun A, Valenzuela-Fernandez A
   J. Biol. Chem., 2009;284(24):16609-20.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


3. Chemokine responsiveness of CD4+ CD25+ regulatory and CD4+ CD25- T cells from atopic and nonatopic donors.
   Authors: Ahern D, Lloyd CM, Robinson DS
   Allergy, 2009;64(8):1121-9.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


4. Infiltrated neutrophils acquire novel chemokine receptor expression and chemokine responsiveness in chronic inflammatory lung diseases.
   Authors: Hartl D, Krauss-Etschmann S, Koller B, Hordijk PL, Kuijpers TW, Hoffmann F, Hector A, Eber E, Marcos V, Bittmann I, Eickelberg O, Griese M, Roos D
   J. Immunol., 2008;181(11):8053-67.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


5. Chemokine production and chemokine receptor expression by human glioma cells: role of CXCL10 in tumour cell proliferation.
   Authors: Maru SV, Holloway KA, Flynn G, Lancashire CL, Loughlin AJ, Male DK, Romero IA
   J. Neuroimmunol., 2008;199(1):35-45.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


6. Chemokine receptors in head and neck cancer: association with metastatic spread and regulation during chemotherapy.
   Authors: Muller A, Sonkoly E, Eulert C, Gerber PA, Kubitza R, Schirlau K, Franken-Kunkel P, Poremba C, Snyderman C, Klotz LO, Ruzicka T, Bier H, Zlotnik A, Whiteside TL, Homey B, Hoffmann TK
   Int. J. Cancer, 2006;118(9):2147-57.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


7. Characterization of the human chemerin receptor--ChemR23/CMKLR1--as co-receptor for human and simian immunodeficiency virus infection, and identification of virus-binding receptor domains.
   Authors: Martensson UE, Fenyo EM, Olde B, Owman C
   Virology, 2006;355(1):6-17.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


8. Chemokine receptor expression on human eosinophils from peripheral blood and bronchoalveolar lavage fluid after segmental antigen challenge.
   Authors: Liu LY, Jarjour NN, Busse WW, Kelly EA
   J. Allergy Clin. Immunol., 2003;112(3):556-62.
   Species: Human
   Sample Type: BALF
   Application: Flow


9. Sequential involvement of CCR2 and CCR6 ligands for immature dendritic cell recruitment: possible role at inflamed epithelial surfaces.
   Authors: Vanbervliet B, Homey B, Durand I, Massacrier C, Ait-Yahia S, de Bouteiller O, Vicari A, Caux C
   Eur J Immunol, 2002;32(1):231-42.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow

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