抗Flt-4抗体(Anti-Flt-4, Mouse-Mono antibody)
掲載日情報：2021/01/28 現在Webページ番号：29137
Flt-4に対する抗体(Anti-Flt-4, Mouse-Mono )です。
※ 本製品は研究用です。研究用以外には使用できません。
追加しました。
- 価格
- Product Details
- Applications and Data
- References
- Related Research Areas
- Related Product & Information
- Citations
価格
[在庫・価格 ：2025年04月26日 20時55分現在]
| 詳細 | 商品名 |
|
文献数 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
Anti-Flt-4, Mouse-Mono(54733) <Anti-VEGF Receptor 3> |
|
4 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
[在庫・価格 ：2025年04月26日 20時55分現在]
Anti-Flt-4, Mouse-Mono(54733) <Anti-VEGF Receptor 3>
文献数： 4
- 商品コード：BAM3492
- メーカー：RSD
- 包装：250μg
- 価格：¥113,000
- 在庫：無(未発注)
- 納期：10日程度 ※※ 表示されている納期は弊社に在庫がなく、取り寄せた場合の目安納期となります。
- 法規制等：
| 説明文 | マッチドペア：Human VEGF R3/Flt-4 サンドイッチELISAの検出用抗体として利用可能，補足用抗体として#MAB349-500，スタンダードとして#349-F4-050を用いる。 別名：EC 2.7.10 クローン：54733 Genbank No： 2324 Protein Accession No： P35916 |
||
|---|---|---|---|
| 法規制等 | |||
| 保存条件 | -20℃ | 法規備考 | |
| 抗原種 | Human | 免疫動物 | Mouse |
| 交差性 | Human | 適用 | ELISA,FCM |
| 標識 | Biotin | 性状 | Protein A/G Affinity Purified |
| 吸収処理 | クラス | IgG | |
| クロナリティ | Monoclonal | フォーマット | |
| 掲載カタログ |
|
||
| 製品記事 | Myeloid-derived Suppressor Cell Marker |
||
| 関連記事 | R&D Systems(R&Dシステムズ)社 ELISA用ペア抗体を使用したELISA 構築ガイド |
||
追加しました。
Product Details
| Species Reactivity | Human |
|---|---|
| Label | Biotin |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant human VEGF R3/Flt-4Tyr25-Ile776Accession # P35916 |
| Source | Monoclonal Mouse IgG1 Clone # 54733 |
| Purification | Protein A or G purified from hybridoma culture supernatant |
| Specificity | Detects human VEGF R3/Flt-4 in direct ELISAs. |
追加しました。
Applications and Data
| Recommended Concentration | Sample | |
| Flow Cytometry | 2.5 µg/106 cells | HUVEC human umbilical vein endothelial cells |
| Human VEGF R3/Flt-4 Sandwich Immunoassay | Reagent | |
| ELISA Capture (Matched Antibody Pair) | 2-8 µg/mL | Human VEGF R3/Flt‑4 Antibody (Catalog #MAB349 ) |
| ELISA Detection (Matched Antibody Pair) | 0.5-2.0 µg/mL | Human VEGF R3/Flt‑4 Biotinylated Antibody (Catalog #BAM3492 ) |
| ELISA Standard | Recombinant Human VEGF R3/Flt-4 Fc Chimera Protein, CF (Catalog #349-F4 ) | |
| Please Note: Optimal dilutions should be determined by each laboratory for each application.General Protocolsare available in the Technical Information section on our website. | Preparation and Storage | |
| Reconstitution | Reconstitute at 0.5 mg/mL in sterile PBS. | Reconstitution Buffer Available |
| Shipping | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. | |
| Stability & Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. | |
| 1 month, 2 to 8 °C under sterile conditions after reconstitution. | ||
| 6 months, -20 to -70 °C under sterile conditions after reconstitution. | ||
| Background: VEGF R3/Flt-4 | VEGF R2 (KDR/Flk-1), VEGF R1 (Flt-1) and VEGF R3 (Flt-4) belong to the class III subfamily of receptor tyrosine kinases (RTKs). All three receptors contain seven immunoglobulin-like repeats in their extracellular domains and kinase insert domains in their intracellular regions. The expression of VEGF R1, 2, and 3 is almost exclusively restricted to the endothelial cells. These receptors are likely to play essential roles in vasculogenesis and angiogenesis. VEGF R3 cDNA encodes a 1298 amino acid (aa) residue precursor protein with a 24 aa residue signal peptide. Mature VEGF R3 is composed of a 751 aa residue extracellular domain, a 22 aa residue transmembrane domain, and a 482 aa residue cytoplasmic domain. Both VEGF-C and VEGF-D have been shown to bind and activate VEGF R3 (Flt-4). VEGF R3 is widely expressed in the early embryo but becomes restricted to lymphatic endothelia at later stages of development. It is likely that VEGF R3 may be important for lymph angiogenesis. |
|
追加しました。
References
| Ferra, N. and R. Davis-Smyth (1997) Endocrine Reviews 18:4. | |
| Long Name: | Vascular Endothelial Growth Factor Receptor 3 |
| Entrez Gene IDs: | 2324 (Human); 14257 (Mouse) |
| Alternate Names: | EC 2.7.10; EC 2.7.10.1; FLT4; Flt-4; fms-related tyrosine kinase 4; LMPH1A; PCLFLT41; soluble VEGFR3 variant 1; soluble VEGFR3 variant 2; soluble VEGFR3 variant 3; Tyrosine-protein kinase receptor FLT4; vascular endothelial growth factor receptor 3; VEGF R3; VEGFR3; VEGFR-3; VEGFR3Fms-like tyrosine kinase 4 |
追加しました。
Related Research Areas
| Airway Inflammation and Remodeling | ||
| Endothelial Cell Markers | ||
| Endothelial Progenitor and Endothelial Cell Markers | ||
| Endothelial Progenitor Cell Markers | ||
| Receptor Tyrosine Kinases (RTKs) | ||
| Receptor Tyrosine Kinases (RTKs) in the Akt Pathway | ||
| Receptors in the Jak/STAT Pathway | ||
| VEGF Family | ||
| VEGF Receptors and Regulators on Endothelial Cells | ||
| ||
追加しました。
Related Product & Information
| Background | VEGF R3/Flt-4 |
|---|---|
| background_content | Background: VEGF R3/Flt-4 VEGF R2 (KDR/Flk-1), VEGF R1 (Flt-1) and VEGF R3 (Flt-4) belong to the class III subfamily of receptor tyrosine kinases (RTKs). All three receptors contain seven immunoglobulin-like repeats in their extracellular domains and kinase insert domains in their intracellular regions. The expression of VEGF R1, 2, and 3 is almost exclusively restricted to the endothelial cells. These receptors are likely to play essential roles in vasculogenesis and angiogenesis.VEGF R3 cDNA encodes a 1298 amino acid (aa) residue precursor protein with a 24 aa residue signal peptide. Mature VEGF R3 is composed of a 751 aa residue extracellular domain, a 22 aa residue transmembrane domain, and a 482 aa residue cytoplasmic domain. Both VEGF-C and VEGF-D have been shown to bind and activate VEGF R3 (Flt-4). VEGF R3 is widely expressed in the early embryo but becomes restricted to lymphatic endothelia at later stages of development. It is likely that VEGF R3 may be important for lymph angiogenesis. |
追加しました。
Citations
- Tumoural expression and circulating level of VEGFR-3 (Flt-4) in metastatic melanoma patients: correlation with clinical parameters and outcome.
Authors: Mouawad R, Spano JP, Comperat E, Capron F, Khayat D
Eur. J. Cancer, 2009;45(8):1407-14.
Species: Human
Sample Type: Serum
Application: ELISA Development - Resistance of acute myeloid leukemic cells to the triterpenoid CDDO-Imidazolide is associated with low caspase-8 and FADD levels.
Authors: Riccioni R, Senese M, Diverio D, Riti V, Mariani G, Boe A, LoCoco F, Foa R, Peschle C, Sporn M, Testa U
Leuk. Res., 2008;32(8):1244-58.
Species: Human
Sample Type: Whole Cells
Application: Flow - Expression of Tie-2 and other receptors for endothelial growth factors in acute myeloid leukemias is associated with monocytic features of leukemic blasts.
Authors: Riccioni R, Diverio D, Mariani G, Buffolino S, Riti V, Saulle E, Petrucci E, Cedrone M, Lo-Coco F, Foa R, Peschle C, Testa U
Stem Cells, 2007;25(8):1862-71.
Species: Human
Sample Type: Whole Cells
Application: Flow - Inhibition of the mammalian target of rapamycin impedes lymphangiogenesis.
Authors: Huber S, Bruns CJ, Schmid G, Hermann PC, Conrad C, Niess H, Huss R, Graeb C, Jauch KW, Heeschen C, Guba M
Kidney Int., 2007;71(8):771-7.
Species: Human
Sample Type: Whole Cells
Application: Flow
追加しました。
製品情報は掲載時点のものですが、価格表内の価格については随時最新のものに更新されます。お問い合わせいただくタイミングにより製品情報・価格などは変更されている場合があります。
表示価格に、消費税等は含まれていません。一部価格が予告なく変更される場合がありますので、あらかじめご了承下さい。