抗IFN-alpha抗体(Anti-IFN-α, Porcine, Mouse-Mono antibody)

• 価格
• Product Details
• Applications and Data
• Related Product & Information
• Citations

価格

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Product Details

Species Reactivity	Porcine
Label	Unconjugated
Immunogen	Porcine IFN-alpha
Source	Monoclonal Mouse IgG1 Clone # F17
Purification	Protein A or G purified from hybridoma culture supernatant
Specificity	Neutralizes pig interferon alpha

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Applications and Data

	Recommended Concentration	Sample
Neutralization

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Related Product & Information

Long Name	Interferon alpha
Entrez Gene IDs	3440 (Human)
Background	IFN-alpha
background_content	Background: IFN-alpha Interferon-alpha (IFN-alpha), also known as leukocyte interferon, represents a group of related but distinct proteins that share over 95% amino acid sequence homology. They are members of the type I interferon family which share a common cell surface receptor composed of two subunits, a 100 kDa ligand-binding subunit (IFN-alpha R2) and a 125 kDa ligand binding and signal transduction subunit (IFN-alpha R1) that is involved both in ligand binding and signal transduction. IFN-alpha has both anti-viral and immunomodulatory activities on target cells.

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Citations

1. Porcine cathelicidins efficiently complex and deliver nucleic acids to plasmacytoid dendritic cells and can thereby mediate bacteria-induced IFN-alpha responses.
   Authors: Baumann A, Demoulins T, Python S, Summerfield A
   J Immunol, 2014;193(1):364-71.
   Species: Porcine
   Sample Type: Whole Cells
   Application: Flow


2. Cytokine protein expression levels in tracheobronchial lymph node homogenates of pigs infected with pseudorabies virus.
   Authors: Miller LC, Zanella EL, Waters WR
   Clin. Vaccine Immunol., 2010;17(5):728-34.
   Species: Porcine
   Sample Type: Tissue Homogenates
   Application: ELISA Development


3. The leader proteinase of foot-and-mouth disease virus inhibits the induction of beta interferon mRNA and blocks the host innate immune response.
   Authors: de Los Santos T, de Avila Botton S, Weiblen R, Grubman MJ
   J. Virol., 2006;80(4):1906-14.
   Species: Porcine
   Sample Type: Cell Culture Supernates
   Application: ELISA Development


4. Fc gamma RII-dependent sensitisation of natural interferon-producing cells for viral infection and interferon-alpha responses.
   Authors: Balmelli C, Vincent IE, Rau H, Guzylack-Piriou L, McCullough K, Summerfield A
   Eur. J. Immunol., 2005;35(8):2406-15.
   Species: Porcine
   Sample Type: Serum
   Application: ELISA Development


5. Classical swine fever virus induces proinflammatory cytokines and tissue factor expression and inhibits apoptosis and interferon synthesis during the establishment of long-term infection of porcine vascular endothelial cells.
   Authors: Bensaude E, Turner JL, Wakeley PR, Sweetman DA, Pardieu C, Drew TW, Wileman T, Powell PP
   J. Gen. Virol., 2004;85(0):1029-37.
   Species: Porcine
   Sample Type: Cell Culture Supernates
   Application: ELISA Development


6. Porcine reproductive and respiratory syndrome virus field isolates differ in in vitro interferon phenotypes.
   Authors: Lee SM, Schommer SK, Kleiboeker SB
   Vet. Immunol. Immunopathol., 2004;102(3):217-31.
   Species: Porcine
   Sample Type: Cell Culture Supernates
   Application: ELISA Development


7. Immediate protection of swine from foot-and-mouth disease: a combination of adenoviruses expressing interferon alpha and a foot-and-mouth disease virus subunit vaccine.
   Authors: Moraes MP, Chinsangaram J, Brum MC, Grubman MJ
   Vaccine, 2003;22(2):268-79.
   Species: Porcine
   Sample Type: Plasma
   Application: ELISA Development

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