抗MMP-9抗体(Anti-MMP-9, Human, Goat-Poly, Biotin antibody)

掲載日情報:2021/01/28 現在Webページ番号:27975

MMP-9に対する抗体(Anti-MMP-9, Human, Goat-Poly, Biotin )です。
本製品は研究用です。研究用以外には使用できません。

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[在庫・価格 :2025年04月26日 20時55分現在]

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Anti-MMP-9, Human, Goat-Poly, Biotin
10日程度 ※ 表示されている納期は弊社に在庫がなく、取り寄せた場合の目安納期となります。 9
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説明文
マッチドペア:Human/Primate MMP-9 サンドイッチELISAの検出用抗体として利用可能,補足用抗体として#MAB936-500,スタンダードとして#911-MP-010を用いる。
別名:92 kDa gelatinase
Genbank No: 4318
法規制等
保存条件 -20℃ 法規備考
抗原種 Human 免疫動物 Goat クラス IgG 標識 Biotin
交差性 Human 適用 ELISA,Western Blot
クロナリティ Polyclonal フォーマット 性状 Antigen Affinity Purified 吸収処理
掲載カタログ

製品記事 Myeloid-derived Suppressor Cell Marker
関連記事 R&D Systems(R&Dシステムズ)社 ELISA用ペア抗体を使用したELISA 構築ガイド

[在庫・価格 :2025年04月26日 20時55分現在]

※ 表示されている納期は弊社に在庫が無く、取り寄せた場合の納期目安となります。

Anti-MMP-9, Human, Goat-Poly, Biotin

文献数: 9

説明文 マッチドペア:Human/Primate MMP-9 サンドイッチELISAの検出用抗体として利用可能,補足用抗体として#MAB936-500,スタンダードとして#911-MP-010を用いる。
別名:92 kDa gelatinase
Genbank No: 4318
法規制等
保存条件 -20℃ 法規備考
抗原種 Human 免疫動物 Goat
交差性 Human 適用 ELISA,Western Blot
標識 Biotin 性状 Antigen Affinity Purified
吸収処理 クラス IgG
クロナリティ Polyclonal フォーマット
掲載カタログ

製品記事 Myeloid-derived Suppressor Cell Marker
関連記事 R&D Systems(R&Dシステムズ)社 ELISA用ペア抗体を使用したELISA 構築ガイド



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Product Details

Species ReactivityHuman, Primate
LabelBiotin
ImmunogenChinese hamster ovary cell line CHO-derived recombinant human MMP-9
SourcePolyclonal Goat IgG
PurificationAntigen Affinity-purified
SpecificityDetects human and primate MMP-9 in ELISAs and Western blots. In sandwich immunoassays, less than 0.1% cross-reactivity with rmMMP-9, rhMMP-1, -2, -3, -7, -8, -10, -12, -13, and -14 is observed.


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Applications and Data

 Recommended
Concentration
Sample
Western Blot0.1 µg/mLRecombinant Human MMP‑9 (Catalog # 911-MP)
Human/Primate MMP-9 Sandwich ImmunoassayReagent
ELISA Capture (Matched Antibody Pair)2-8 µg/mL Human/Primate MMP‑9 Antibody (Catalog #MAB936 )
ELISA Detection (Matched Antibody Pair)0.1-0.4 µg/mL Human/Primate MMP‑9 Biotinylated Antibody (Catalog #BAF911 )
ELISA Standard  Recombinant Human MMP-9 Protein, CF (Catalog #911-MP )
Please Note: Optimal dilutions should be determined by each laboratory for each application.General Protocolsare available in the Technical Information section on our website.Preparation and Storage
ReconstitutionReconstitute at 0.2 mg/mL in sterile PBS.Reconstitution Buffer Available
ShippingThe product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: MMP-9

Matrix metalloproteinases are a family of zinc and calcium dependent endopeptidases with the combined ability to degrade all the components of the extracellular matrix. MMP-9 (gelatinase B) can degrade a broad range of substrates including gelatin, collagen types IV and V, elastin and proteoglycan core protein. It is believed to act synergistically with interstitial collagenase (MMP-1) in the degradation of fibrillar collagens as it degrades their denatured gelatin forms. MMP-9 is produced by keratinocytes, monocytes, macrophages and PMN leukocytes. MMP-9 is present in most cases of inflammatory responses. Structurally, MMP-9 maybe be divided into five distinct domains: a pro-domain which is cleaved upon activation, a gelatin-binding domain consisting of three contiguous fibronectin type II units, a catalytic domain containing the zinc binding site, a proline-rich linker region, and a carboxyl terminal hemopexin-like domain.

Long Name:Matrix Metalloproteinase 9
Entrez Gene IDs:4318 (Human); 17395 (Mouse); 81687 (Rat)
Alternate Names:92 kDa gelatinase; 92 kDa type IV collagenase; CLG4B; EC 3.4.24; EC 3.4.24.35; Gelatinase B; GELB; macrophage gelatinase; MANDP2; matrix metallopeptidase 9; matrix metalloproteinase 9; matrix metalloproteinase-9; MMP9; MMP-9; type V collagenase

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Related Research Areas

Airway Inflammation and Remodeling
Alpha Granule Soluble Molecules
Cancer Biomarkers
Cell to Cell Adhesion Disassembly During EMT
Collagen Modifying Enzymes
Enzymes Secreted by Endothelial Cells
Extracellular Matrix Remodeling and Cell Migration During EMT
Gametes and Fertilization
Inflammatory Mediators
Mesenchymal Cells and EMT
Metalloproteases and Regulators
MMPs, TIMPs and Related Molecules
Molecules Secreted by VSMC
Preeclampsia
Proteolytic Degradation of Amyloid beta
  1. Activation of D2 dopamine receptors in CD133+ve cancer stem cells in non-small cell lung carcinoma inhibits proliferation, clonogenic ability and invasiveness of these cells
    Authors: Soumyabrata Roy
    J. Biol. Chem, 2016;0(0):.
    Species: Human
    Sample Type: Cell Culture Supernates
    Application: ELISA detection


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Related Product & Information

BackgroundMMP-9
background_contentBackground:
MMP-9
Matrix metalloproteinases are a family of zinc and calcium dependent endopeptidases with the combined ability to degrade all the components of the extracellular matrix. MMP-9 (gelatinase B) can degrade a broad range of substrates including gelatin, collagen types IV and V, elastin and proteoglycan core protein. It is believed to act synergistically with interstitial collagenase (MMP-1) in the degradation of fibrillar collagens as it degrades their denatured gelatin forms. MMP-9 is produced by keratinocytes, monocytes, macrophages and PMN leukocytes. MMP-9 is present in most cases of inflammatory responses. Structurally, MMP-9 maybe be divided into five distinct domains: a pro-domain which is cleaved upon activation, a gelatin-binding domain consisting of three contiguous fibronectin type II units, a catalytic domain containing the zinc binding site, a proline-rich linker region, and a carboxyl terminal hemopexin-like domain.


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Citations

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
  1. Activation of D2 dopamine receptors in CD133+ve cancer stem cells in non-small cell lung carcinoma inhibits proliferation, clonogenic ability and invasiveness of these cells
    Authors: Soumyabrata Roy
    J. Biol. Chem, 2016;0(0):.
    Species: Human
    Sample Type: Cell Culture Supernates
    Application: ELISA detection

  2. Neutrophils from vasculitis patients exhibit an increased propensity for activation by anti-neutrophil cytoplasmic antibodies.
    Authors: Ohlsson S, Ohlsson S, Soderberg D, Gunnarsson L, Pettersson A, Segelmark M, Hellmark T
    Clin Exp Immunol, 2014;176(3):363-72.
    Species: Human
    Sample Type: Cell Culture Supernates
    Application: ELISA detection

  3. Long-term weight loss decreases the nontraditional cardiovascular risk factors interleukin-18 and matrix metalloproteinase-9 in obese subjects.
    Authors: Madsen EL, Bruun JM, Skogstrand K, Hougaard DM, Christiansen T, Richelsen B
    Metab. Clin. Exp., 2009;58(7):946-53.
    Species: Human
    Sample Type: Serum
    Application: Luminex Assay Development

  4. Development and validation of sandwich ELISA microarrays with minimal assay interference.
    Authors: Gonzalez RM, Seurynck-Servoss SL, Crowley SA
    J. Proteome Res., 2008;7(6):2406-14.
    Species: Human
    Sample Type: Serum
    Application: ELISA Microarray Development



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