抗Flk-1抗体(Anti-Flk-1, Mouse, Goat-Poly, Biotin antibody)
掲載日情報：2021/01/28 現在Webページ番号：27827
Flk-1に対する抗体(Anti-Flk-1, Mouse, Goat-Poly, Biotin )です。
※ 本製品は研究用です。研究用以外には使用できません。
追加しました。
- 価格
- Product Details
- Applications and Data
- References
- Related Research Areas
- Related Product & Information
- Citations
価格
[在庫・価格 ：2025年04月26日 20時35分現在]
| 詳細 | 商品名 |
|
文献数 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
Anti-Flk-1, Mouse, Goat-Poly, Biotin <Anti-VEGF Receptor 2> |
|
4 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
[在庫・価格 ：2025年04月26日 20時35分現在]
Anti-Flk-1, Mouse, Goat-Poly, Biotin <Anti-VEGF Receptor 2>
文献数： 4
- 商品コード：BAF644
- メーカー：RSD
- 包装：50μg
- 価格：¥113,000
- 在庫：無(未発注)
- 納期：10日程度 ※※ 表示されている納期は弊社に在庫がなく、取り寄せた場合の目安納期となります。
- 法規制等：
| 説明文 | マッチドペア：Mouse VEGF R2/Flk-1 サンドイッチELISAの検出用抗体として利用可能，補足用抗体として#MAB4431-500，スタンダードとして#443-KD-050を用いる。 別名：CD309 Genbank No： 3791 Protein Accession No： P35918 |
||
|---|---|---|---|
| 法規制等 | |||
| 保存条件 | -20℃ | 法規備考 | |
| 抗原種 | Mouse | 免疫動物 | Goat |
| 交差性 | Mouse | 適用 | ELISA,FCM,Western Blot |
| 標識 | Biotin | 性状 | Antigen Affinity Purified |
| 吸収処理 | クラス | IgG | |
| クロナリティ | Polyclonal | フォーマット | |
| 掲載カタログ |
|
||
| 製品記事 | Myeloid-derived Suppressor Cell Marker |
||
| 関連記事 | R&D Systems(R&Dシステムズ)社 ELISA用ペア抗体を使用したELISA 構築ガイド |
||
追加しました。
Product Details
| Species Reactivity | Mouse |
|---|---|
| Label | Biotin |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant mouse VEGF R2/KDR/Flk-1Ala20-Glu762Accession # P35918 |
| Source | Polyclonal Goat IgG |
| Purification | Antigen Affinity-purified |
| Specificity | Detects mouse VEGF R2/KDR/Flk-1 in ELISAs and Western blots. In sandwich ELISAs, less than 0.5% cross-reactivity with recombinant human VEGF R2, recombinant mouse (rm) VEGF164, rmVEGF R1, rmVEGF R3, rmVEGF-B, and rmVEGF-D is observed. |
追加しました。
Applications and Data
| Recommended Concentration | Sample | |
| Western Blot | 0.1 µg/mL | Recombinant Mouse VEGF R2/KDR/Flk‑1 Fc Chimera (Catalog # 443-KD) |
| Flow Cytometry | 2.5 µg/106 cells | bEnd.3 mouse endothelioma cell line |
| Mouse VEGF R2/Flk-1 Sandwich Immunoassay | Reagent | |
| ELISA Capture (Matched Antibody Pair) | 2-8 µg/mL | Mouse VEGF R2/KDR/Flk‑1 Antibody (Catalog #MAB4431 ) |
| ELISA Detection (Matched Antibody Pair) | 0.1-0.4 µg/mL | Mouse VEGF R2/KDR/Flk‑1 Biotinylated Antibody (Catalog #BAF644 ) |
| ELISA Standard | Recombinant Mouse VEGF R2/Flk-1 Fc Chimera Protein (Catalog #443-KD ) | |
| Please Note: Optimal dilutions should be determined by each laboratory for each application.General Protocolsare available in the Technical Information section on our website. | Preparation and Storage | |
| Reconstitution | Reconstitute at 0.2 mg/mL in sterile PBS. | Reconstitution Buffer Available |
| Shipping | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. | |
| Stability & Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. | |
| 1 month, 2 to 8 °C under sterile conditions after reconstitution. | ||
| 6 months, -20 to -70 °C under sterile conditions after reconstitution. | ||
| Background: VEGF R2/KDR/Flk-1 | VEGF R2 (KDR/Flk-1), VEGF R1 (Flt-1) and VEGF R3 (Flt-4) belong to the class III subfamily of receptor tyrosine kinases (RTKs). All three receptors contain seven immunoglobulin-like repeats in their extracellular domains and kinase insert domains in their intracellular regions. The expression of VEGF R1, 2, and 3 is almost exclusively restricted to the endothelial cells. These receptors are likely to play essential roles in vasculogenesis and angiogenesis. Mouse VEGF R2 cDNA encodes a 1367 amino acid (aa) residue precursor protein with a 19 aa residue signal peptide. Mature VEGF R2 is composed of a 743 aa residue extracellular domain, a 22 aa residue transmembrane domain and a 583 aa residue cytoplasmic domain. In contrast to VEGF R1 which binds both PlGF and VEGF with high affinity, VEGF R2 binds VEGF but not PlGF with high affinity. The recombinant soluble VEGF R2/Fc chimera binds VEGF with high affinity and is a potent VEGF antagonist. |
|
追加しました。
References
| Ferra, N. and R. Davis-Smyth (1997) Endocrine Reviews 18:4. | |
| Achen, M.G. et al. (1998) Proc. Natl. Acad. Sci. USA 95:548. | |
| Long Name: | Vascular Endothelial Growth Factor Receptor 2 |
| Entrez Gene IDs: | 3791 (Human); 16542 (Mouse) |
| Alternate Names: | CD309 antigen; CD309; EC 2.7.10; EC 2.7.10.1; Fetal liver kinase 1; fetal liver kinase-1; Flk1; Flk-1; FLK1tyrosine kinase growth factor receptor; KDR; kinase insert domain receptor (a type III receptor tyrosine kinase); Kinase insert domain receptor; Protein-tyrosine kinase receptor flk-1; soluble VEGFR2; vascular endothelial growth factor receptor 2; VEGF R2; VEGFR; VEGFR2; VEGFR-2 |
追加しました。
Related Research Areas
| Airway Inflammation and Remodeling | ||
| Cancer Biomarkers | ||
| Cytokine and Growth Factor Receptors on VSMC | ||
| Endothelial Cell Differentiation Markers | ||
| Endothelial Cell Markers | ||
| Endothelial Progenitor and Endothelial Cell Markers | ||
| Endothelial Progenitor Cell Markers | ||
| Hemangioblasts | ||
| Hematopoietic Stem Cell Markers | ||
| HIF Transcription Factors | ||
| Myeloid-derived Suppressor Cells (MDSC) | ||
| Receptor Tyrosine Kinases (RTKs) | ||
| Receptor Tyrosine Kinases (RTKs) in the Akt Pathway | ||
| Receptors in the Jak/STAT Pathway | ||
| Semaphorins, Plexin Receptors, and Related Molecules | ||
| VEGF Family | ||
| VEGF Receptors and Regulators on Endothelial Cells | ||
| ||
追加しました。
Related Product & Information
| Background | VEGF R2/KDR/Flk-1 |
|---|---|
| background_content | Background: VEGF R2/KDR/Flk-1 VEGF R2 (KDR/Flk-1), VEGF R1 (Flt-1) and VEGF R3 (Flt-4) belong to the class III subfamily of receptor tyrosine kinases (RTKs). All three receptors contain seven immunoglobulin-like repeats in their extracellular domains and kinase insert domains in their intracellular regions. The expression of VEGF R1, 2, and 3 is almost exclusively restricted to the endothelial cells. These receptors are likely to play essential roles in vasculogenesis and angiogenesis. Mouse VEGF R2 cDNA encodes a 1367 amino acid (aa) residue precursor protein with a 19 aa residue signal peptide. Mature VEGF R2 is composed of a 743 aa residue extracellular domain, a 22 aa residue transmembrane domain and a 583 aa residue cytoplasmic domain. In contrast to VEGF R1 which binds both PlGF and VEGF with high affinity, VEGF R2 binds VEGF but not PlGF with high affinity. The recombinant soluble VEGF R2/Fc chimera binds VEGF with high affinity and is a potent VEGF antagonist. |
追加しました。
Citations
- A novel two-step procedure to expand cardiac Sca-1+ cells clonally.
Authors: Tang YL, Shen L, Qian K, Phillips MI
Biochem. Biophys. Res. Commun., 2007;359(4):877-83.
Species: Mouse
Sample Type: Whole Cells
Application: ICC
追加しました。
製品情報は掲載時点のものですが、価格表内の価格については随時最新のものに更新されます。お問い合わせいただくタイミングにより製品情報・価格などは変更されている場合があります。
表示価格に、消費税等は含まれていません。一部価格が予告なく変更される場合がありますので、あらかじめご了承下さい。