抗IL-21抗体(Anti-IL-21, Mouse, Goat-Poly, Biotin antibody)

掲載日情報:2021/01/28 現在Webページ番号:27794

IL-21に対する抗体(Anti-IL-21, Mouse, Goat-Poly, Biotin )です。
本製品は研究用です。研究用以外には使用できません。

価格

[在庫・価格 :2026年04月06日 15時35分現在]

※ 表示されている納期は弊社に在庫が無く、取り寄せた場合の納期目安となります。
詳細 商品名
  • 商品コード
  • メーカー
  • 包装
  • 価格
  • 在庫
  • 法規制等
納期 文献数
Anti-IL-21, Mouse, Goat-Poly, Biotin
10日程度 ※ 表示されている納期は弊社に在庫がなく、取り寄せた場合の目安納期となります。 9
  • 使用文献
  • メーカーサイト
  • お問い合わせ
説明文
マッチドペア:Mouse IL-21 サンドイッチELISAの検出用抗体として利用可能,補足用抗体として#AF594,スタンダードとして#594-ML-010を用いる。
別名:IL21
Genbank No: 59067
Protein Accession No: Q9ES17
法規制等
保存条件 -20℃ 法規備考
抗原種 Mouse 免疫動物 Goat クラス IgG 標識 Biotin
交差性 Mouse 適用 ELISA,Western Blot
クロナリティ Polyclonal フォーマット 性状 Antigen Affinity Purified 吸収処理
掲載カタログ

製品記事 Helper T Cells Marker Antibodies
関連記事 R&D Systems(R&Dシステムズ)社 ELISA用ペア抗体を使用したELISA 構築ガイド

[在庫・価格 :2026年04月06日 15時35分現在]

※ 表示されている納期は弊社に在庫が無く、取り寄せた場合の納期目安となります。

Anti-IL-21, Mouse, Goat-Poly, Biotin

文献数: 9

説明文 マッチドペア:Mouse IL-21 サンドイッチELISAの検出用抗体として利用可能,補足用抗体として#AF594,スタンダードとして#594-ML-010を用いる。
別名:IL21
Genbank No: 59067
Protein Accession No: Q9ES17
法規制等
保存条件 -20℃ 法規備考
抗原種 Mouse 免疫動物 Goat
交差性 Mouse 適用 ELISA,Western Blot
標識 Biotin 性状 Antigen Affinity Purified
吸収処理 クラス IgG
クロナリティ Polyclonal フォーマット
掲載カタログ

製品記事 Helper T Cells Marker Antibodies
関連記事 R&D Systems(R&Dシステムズ)社 ELISA用ペア抗体を使用したELISA 構築ガイド



目次に戻る

Product Details

Species ReactivityMouse
LabelBiotin
ImmunogenE. coli-derived recombinant mouse IL‑21 (R&D Systems, Catalog # 594-ML)Pro25-Ser146Accession # Q9ES17
SourcePolyclonal Goat IgG
PurificationAntigen Affinity-purified
SpecificityDetects mouse IL-21 in ELISAs and Western blots. In sandwich immunoassays, less than 0.5% cross-reactivity with recombinant mouse (rm) IL‑2, rmIL‑4, rmIL‑15, and recombinant human IL‑21 is observed.


目次に戻る

Applications and Data

 Recommended
Concentration
Sample
Western Blot0.1 µg/mLRecombinant Mouse IL‑21 (Catalog # 594-ML)
Mouse IL-21 Sandwich ImmunoassayReagent
ELISA Capture (Matched Antibody Pair)0.2-0.8 µg/mL Mouse IL‑21 Antibody (Catalog #AF594 )
ELISA Detection (Matched Antibody Pair)0.1-0.4 µg/mL Mouse IL‑21 Biotinylated Antibody (Catalog #BAF594 )
ELISA Standard  Recombinant Mouse IL-21 Protein (Catalog #594-ML )
Please Note: Optimal dilutions should be determined by each laboratory for each application.General Protocolsare available in the Technical Information section on our website.Preparation and Storage
ReconstitutionReconstitute at 0.2 mg/mL in sterile PBS.Reconstitution Buffer Available
ShippingThe product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: IL-21

Interleukin-21 (IL-21) and its receptor appear to play important roles in the regulation of the immune system. IL-21 is most related to IL-2, IL-4, and IL-15. IL-21 R, also called NILR (novel interleukin receptor), is a type I cytokine receptor with 4 conserved cysteine residues and an extracellular WSXWS motif. It is most closely related to IL-2 R beta and IL-4 R alpha. Mouse IL-21 is a 146 amino acid (aa) residue protein with a 24 aa signal peptide. Mouse and human IL-21 share 57% amino acid identity. IL‑21 is expressed by activated T cells. Although not fully elucidated, the IL-2 R gamma ( gamma c) chain appears to play a role in IL-21 R signaling. The IL-21/IL-21 R interaction appear to play important roles in B and T cell proliferation after antigen stimulation and NK cell maturation.

目次に戻る

References

Parrish-Novak, et al. (2000) Nature 408:57.
Ozaki, K. et al. (2000) Proc. Natl. Acad. Sci. USA 97:11439.
Dumoutier, L. et al. (2000) Proc. Natl. Acad. Sci. USA 97:10144.
Asao, H. et al. (2001) J. Immunol. 167:1.
Long Name:Interleukin 21
Entrez Gene IDs:59067 (Human); 60505 (Mouse); 365769 (Rat); 442935 (Canine); 100344172 (Rabbit)
Alternate Names:IL21; IL-21; IL-21Za11interleukin-21; interleukin 21; interleukin-21 isoform

目次に戻る

Related Research Areas

B Cell Markers
Common gamma Chain Receptor Family
Cytokines and Receptors in Tfh Cell Differentiation and Function
Isolation, Culture, and Identification of Natural Killer Cells
Multiple Sclerosis and Myelin Related Molecules
Natural Killer T (NKT) Cells
Th17 Cells
Th2 Cells
Th22 Cells
Th9 Cells
  1. Prostaglandin E2 inhibits Tr1 cell differentiation through suppression of c-Maf
    Authors: KM Hooper, W Kong, D Ganea
    PLoS ONE, 2017;12(6):e0179184.
    Species: Mouse
    Sample Type: Cell Culture Supernates


目次に戻る

Related Product & Information

BackgroundIL-21
background_contentBackground:
IL-21
Interleukin-21 (IL-21) and its receptor appear to play important roles in the regulation of the immune system. IL-21 is most related to IL-2, IL-4, and IL-15. IL-21 R, also called NILR (novel interleukin receptor), is a type I cytokine receptor with 4 conserved cysteine residues and an extracellular WSXWS motif. It is most closely related to IL-2 R beta and IL-4 R alpha. Mouse IL-21 is a 146 amino acid (aa) residue protein with a 24 aa signal peptide. Mouse and human IL-21 share 57% amino acid identity. IL‑21 is expressed by activated T cells. Although not fully elucidated, the IL-2 R gamma ( gamma c) chain appears to play a role in IL-21 R signaling. The IL-21/IL-21 R interaction appear to play important roles in B and T cell proliferation after antigen stimulation and NK cell maturation.


目次に戻る

Citations

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
  1. Prostaglandin E2 inhibits Tr1 cell differentiation through suppression of c-Maf
    Authors: KM Hooper, W Kong, D Ganea
    PLoS ONE, 2017;12(6):e0179184.
    Species: Mouse
    Sample Type: Cell Culture Supernates

  2. Interleukin-21 is critically required in autoimmune and allogeneic responses to islet tissue in murine models.
    Authors: McGuire HM, Walters S, Vogelzang A
    Diabetes, 2011;60(3):867-75.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Flow

  3. IL-28 supplants requirement for T(reg) cells in protein sigma1-mediated protection against murine experimental autoimmune encephalomyelitis (EAE).
    Authors: Rynda A, Maddaloni M, Ochoa-Reparaz J, Callis G, Pascual DW
    PLoS ONE, 2010;5(1):e8720.
    Species: Mouse
    Sample Type: Cell Culture Supernates
    Application: ELISA Development

  4. Regulation of the IL-21 gene by the NF-kappaB transcription factor c-Rel.
    Authors: Chen G, Hardy K, Bunting K
    J. Immunol., 2010;185(4):2350-9.
    Species: Mouse
    Sample Type: Serum
    Application: ELISA Development

  5. Cytokine-secreting follicular T cells shape the antibody repertoire.
    Authors: Reinhardt RL, Liang HE, Locksley RM
    Nat. Immunol., 2009;10(4):385-93.
    Species: Mouse
    Sample Type: Whole Cells
    Application: ELISpot Development

  6. Tumor-specific Th17-polarized cells eradicate large established melanoma.
    Authors: Muranski P, Boni A, Antony PA, Cassard L, Irvine KR, Kaiser A, Paulos CM, Palmer DC, Touloukian CE, Ptak K, Gattinoni L, Wrzesinski C, Hinrichs CS, Kerstann KW, Feigenbaum L, Chan CC, Restifo NP
    Blood, 2008;112(2):362-73.
    Species: Mouse
    Sample Type: Cell Culture Supernates
    Application: ELISA Development



目次に戻る

お問い合わせ先

(テクニカルサポート 試薬担当)

reagent@funakoshi.co.jp

製品情報は掲載時点のものですが、価格表内の価格については随時最新のものに更新されます。お問い合わせいただくタイミングにより製品情報・価格などは変更されている場合があります。
表示価格に、消費税等は含まれていません。一部価格が予告なく変更される場合がありますので、あらかじめご了承下さい。