Human VEGF R1/Flt-1 Quantikine ELISA Kit, 3rd Generation
掲載日情報：2018/02/01 現在Webページ番号：206223
R&D Systems製のHuman VEGF R1/Flt-1, 3rd Generationを測定するELISAキットです。
※本製品は研究用です。研究用以外には使用できません。
[在庫・価格 ：2025年04月27日 00時00分現在]
※ 表示されている納期は弊社に在庫が無く、取り寄せた場合の納期目安となります。
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Human VEGF R1/Flt-1 Quantikine ELISA Kit, 3rd Gen |
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[在庫・価格 ：2025年04月27日 00時00分現在]
※ 表示されている納期は弊社に在庫が無く、取り寄せた場合の納期目安となります。
Human VEGF R1/Flt-1 Quantikine ELISA Kit, 3rd Gen
文献数： 67
- 商品コード：DVR100C
- メーカー：RSD
- 包装：1kit
- 価格：¥116,000
- 在庫：3個以上
- 納期：10日程度 ※※ 表示されている納期は弊社に在庫がなく、取り寄せた場合の目安納期となります。
- 法規制等：
| 説明文 | 感度：8.46 pg/mL，測定範囲：31.3-2,000 pg/mL，測定試料：Serum, Plasma, Cell Culture Supernatant, Saliva, Tissue Lysate，種交差性：Human，検出方法：colorimetric，測定波長：450 nm，アッセイ法：Sandwich，アッセイ数：96，別売品コントロール：QC239，測定時間：4.5 hours，測定因子：VEGFR1, Flt-1 別名：EC 2.7.10 Genbank No： 2321 |
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| 保存条件 | 4℃ | 法規備考 | |
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| 製品記事 | ELISA Kit製品に関するFAQ（R&D Systems） |
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| 関連記事 | R&D Systems Quantikine ELISA Kit／DuoSet Kit特集 Quantikine ELISA Kit |
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Product Details
- Assay Length
- 4.5 hours
- Sample Type & Volume Required Per Well
- Cell Culture Supernates (100 uL), Cell Lysates (10 uL), Serum (100 uL), EDTA Plasma (100 uL), Heparin Plasma (100 uL), Saliva (100 uL)
- Sensitivity
- 8.46 pg/mL
- Assay Range
- 31.3 - 2,000 pg/mL (Cell Culture Supernates, Cell Lysates, Serum, EDTA Plasma, Heparin Plasma, Saliva)
- Specificity
- Natural and recombinant human soluble VEGF R1
- Interference
- No significant interference observed with available related molecules.
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Product Summary
The Quantikine Human VEGF R1 Immunoassay is a 4.5 hour solid-phase ELISA designed to measure human soluble VEGF R1 in cell culture supernates, serum, plasma, saliva, and follicular fluid. It contains Sf 21-expressed recombinant human VEGF R1/Fc Chimera and has been shown to accurately quantitate the recombinant factor. Results obtained using natural human VEGF R1 showed linear curves that were parallel to the standard curves obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for naturally occurring soluble VEGF R1.
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Precision
Intra-Assay Precision (Precision within an assay) Three samples of known concentration were tested on one plate to assess intra-assay precision.Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision
Inter-Assay Precision (Precision between assays) Three samples of known concentration were tested in separate assays to assess inter-assay precision.Three samples of known concentration were tested in twenty separate assays to assess inter-assay precision. Assays were performed by at least three technicians using two lots of components
Cell Culture Supernates, Cell Lysates, Serum, EDTA Plasma, Heparin Plasma, Saliva
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Recovery
The recovery of VEGF R1 spiked to levels throughout the range of the assay in various matrices was evaluated.
| Sample Type | Average % Recovery | Range % |
|---|---|---|
| Cell Culture Media (n=4) | 99 | 87-110 |
| Cell Lysis Buffer (n=4) | 94 | 86-108 |
| EDTA Plasma (n=4) | 92 | 84-98 |
| Heparin Plasma (n=4) | 89 | 81-96 |
| Saliva (n=4) | 109 | 96-124 |
| Serum (n=4) | 104 | 93-114 |
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Linearity
To assess the linearity of the assay, samples containing and/or spiked with high concentrations of VEGF R1 were serially diluted with Calibrator Diluent to produce samples with values within the dynamic range of the assay.
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Additional Infomation
- Entrez Gene IDs
- 2321 (Human); 14254 (Mouse)
- Background
- VEGF R1/Flt-1
- VEGF R1 (Flt-1), VEGF R2 (KDR/Flk-1), and VEGF R3 (Flt-4) belong to the class III subfamily of receptor tyrosine kinases (RTKs). All three receptors contain seven immunoglobulin-like repeats in their extracellular domain and kinase insert domains in their intracellular region. They are best known for regulating VEGF family-mediated vasculogenesis, angiogenesis, and lymphangiogenesis. They are also mediators of neurotrophic activity and regulators of hematopoieticdevelopment. VEGF R2 is thought to be the primary inducer of VEGF-mediated blood vessel growth, while VEGF R3 plays a significant role in VEGF-C and VEGF-D-mediated lymphangiogenesis.
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Citations
R&D Systems personnel manually curate a database that contains references using R&D Systems products.
The data collected includes not only links to publications in PubMed,
but also provides information about sample types, species, and experimental conditions.
Endothelial Dysfunction in Severe Preeclampsia is Mediated by Soluble Factors, Rather than Extracellular Vesicles
Authors: M O'Brien, D Baczyk, JC Kingdom
Sci Rep, 2017;7(1):5887.
Species: Human
Sample Type: Tissue Culture Supernates
Authors: M O'Brien, D Baczyk, JC Kingdom
Sci Rep, 2017;7(1):5887.
Species: Human
Sample Type: Tissue Culture Supernates
Albuminuria Is Associated with Endothelial Dysfunction and Elevated Plasma Endothelin-1 in Sickle Cell Anemia
PLoS ONE, 2016;11(9):e0162652.
Species: Human
Sample Type: Plasma
PLoS ONE, 2016;11(9):e0162652.
Species: Human
Sample Type: Plasma
Association between Placental Lesions, Cytokines and Angiogenic Factors in Pregnant Women with Preeclampsia
Authors: Ingrid C Weel
PLoS ONE, 2016;11(6):e0157584.
Species: Human
Sample Type: Tissue Homogenates
Authors: Ingrid C Weel
PLoS ONE, 2016;11(6):e0157584.
Species: Human
Sample Type: Tissue Homogenates
Inhibition of placental growth factor in renal cell carcinoma.
Authors: Bessho H, Wong B, Huang D, Siew E, Huang D, Tan J, Ong C, Tan S, Matsumoto K, Iwamura M, Teh B
Anticancer Res, 2015;35(1):531-41.
Species: Human
Sample Type: Cell Culture Supernates
Authors: Bessho H, Wong B, Huang D, Siew E, Huang D, Tan J, Ong C, Tan S, Matsumoto K, Iwamura M, Teh B
Anticancer Res, 2015;35(1):531-41.
Species: Human
Sample Type: Cell Culture Supernates
Serum angiopoietin-2 and soluble VEGFR-2 levels predict malignancy of ovarianneoplasm and poor prognosis in epithelial ovarian cancer.
Authors: Sallinen H, Heikura T, Koponen J, Kosma V, Heinonen S, Yla-Herttuala S, Anttila M
BMC Cancer, 2014;14(0):696.
Species: Human
Sample Type: Serum
Authors: Sallinen H, Heikura T, Koponen J, Kosma V, Heinonen S, Yla-Herttuala S, Anttila M
BMC Cancer, 2014;14(0):696.
Species: Human
Sample Type: Serum
FLT1 genetic variation predisposes to neovascular AMD in ethnically diverse populations and alters systemic FLT1 expression.
Authors: Owen, Leah A, Morrison, Margaux, Ahn, Jeeyun, Woo, Se Joon, Sato, Hajime, Robinson, Rosann, Morgan, Denise J, Zacharaki, Fani, Simeonova, Marina, Uehara, Hironori, Chakravarthy, Usha, Hogg, Ruth E, Ambati, Balamura, Kotoula, Maria, Baehr, Wolfgang, Haider, Neena B, Silvestri, Giuliana, Miller, Joan W, Tsironi, Evangeli, Farrer, Lindsay, Kim, Ivana K, Park, Kyu Hyun, DeAngelis, Margaret
Invest Ophthalmol Vis Sci, 2014;55(6):3543-54.
Species: Human
Sample Type: Serum
Authors: Owen, Leah A, Morrison, Margaux, Ahn, Jeeyun, Woo, Se Joon, Sato, Hajime, Robinson, Rosann, Morgan, Denise J, Zacharaki, Fani, Simeonova, Marina, Uehara, Hironori, Chakravarthy, Usha, Hogg, Ruth E, Ambati, Balamura, Kotoula, Maria, Baehr, Wolfgang, Haider, Neena B, Silvestri, Giuliana, Miller, Joan W, Tsironi, Evangeli, Farrer, Lindsay, Kim, Ivana K, Park, Kyu Hyun, DeAngelis, Margaret
Invest Ophthalmol Vis Sci, 2014;55(6):3543-54.
Species: Human
Sample Type: Serum
Analysis of plasma cytokines and angiogenic factors in patients with pretreated urothelial cancer receiving Pazopanib: the role of circulating interleukin-8 toenhance the prognostic accuracy.
Authors: Necchi A, Pennati M, Zaffaroni N, Landoni E, Giannatempo P, Raggi D, Schwartz L, Morosi C, Crippa F, Fare E, Nicolai N, Lanocita R, Sava T, Sacco C, Messina C, Ortega C, De Braud F, Salvioni R, Daidone M, Gianni A, Mariani L
Br J Cancer, 2014;110(1):26-33.
Species: Human
Sample Type: Plasma
Authors: Necchi A, Pennati M, Zaffaroni N, Landoni E, Giannatempo P, Raggi D, Schwartz L, Morosi C, Crippa F, Fare E, Nicolai N, Lanocita R, Sava T, Sacco C, Messina C, Ortega C, De Braud F, Salvioni R, Daidone M, Gianni A, Mariani L
Br J Cancer, 2014;110(1):26-33.
Species: Human
Sample Type: Plasma
Placental growth factor and soluble Fms-like tyrosine kinase 1 in diabeticpregnancy: A possible relation to distal villous immaturity.
Authors: El-Tarhouny S, Almasry S, Elfayomy A, Baghdadi H, Habib F
Histol Histopathol, 2014;29(2):259-72.
Species: Human
Sample Type: Serum
Authors: El-Tarhouny S, Almasry S, Elfayomy A, Baghdadi H, Habib F
Histol Histopathol, 2014;29(2):259-72.
Species: Human
Sample Type: Serum
Persistent urinary podocyte loss following preeclampsia may reflect subclinical renal injury.
Authors: White W, Garrett A, Craici I, Wagner S, Fitz-Gibbon P, Butters K, Brost B, Rose C, Grande J, Garovic V
PLoS ONE, 2014;9(3):e92693.
Species: Human
Sample Type: Serum
Authors: White W, Garrett A, Craici I, Wagner S, Fitz-Gibbon P, Butters K, Brost B, Rose C, Grande J, Garovic V
PLoS ONE, 2014;9(3):e92693.
Species: Human
Sample Type: Serum
Advanced oxidation protein products enhances soluble Fms-like tyrosine kinase 1 expression in trophoblasts: a possible link between oxidative stress and preeclampsia.
Authors: Huang Q, Wang S, Zhang M, Huang L, Tian J, Yu Y, Wang Z, Zhong M
Placenta, 2013;34(10):949-52.
Species: Human
Sample Type: Cell Culture Supernates
Authors: Huang Q, Wang S, Zhang M, Huang L, Tian J, Yu Y, Wang Z, Zhong M
Placenta, 2013;34(10):949-52.
Species: Human
Sample Type: Cell Culture Supernates
Role of serum concentration of VEGFR1 and TIMP2 on clinical outcome in primarycervical cancer: results of a companion protocol of the randomized, NOGGO-AGOphase III adjuvant trial of simultaneous cisplatin-based radiochemotherapy vs.carboplatin and paclitaxel containing sequential radiotherapy.
Authors: Braicu E, Fotopoulou C, Chekerov R, Richter R, Blohmer J, Kummel S, Stamatian F, Yalcinkaya I, Mentze M, Lichtenegger W, Sehouli J
Cytokine, 2013;61(3):755-8.
Species: Human
Sample Type: Serum
Authors: Braicu E, Fotopoulou C, Chekerov R, Richter R, Blohmer J, Kummel S, Stamatian F, Yalcinkaya I, Mentze M, Lichtenegger W, Sehouli J
Cytokine, 2013;61(3):755-8.
Species: Human
Sample Type: Serum
Integrating multiple 'omics' analyses identifies serological protein biomarkers for preeclampsia.
Authors: Liu, Linda Y, Yang, Ting, Ji, Jun, Wen, Qiaojun, Morgan, Alexande, Jin, Bo, Chen, Gongxing, Lyell, Deirdre, Stevenson, David K, Ling, Xuefeng, Butte, Atul J
BMC Med, 2013;11(0):236.
Species: Human
Sample Type: Serum
Authors: Liu, Linda Y, Yang, Ting, Ji, Jun, Wen, Qiaojun, Morgan, Alexande, Jin, Bo, Chen, Gongxing, Lyell, Deirdre, Stevenson, David K, Ling, Xuefeng, Butte, Atul J
BMC Med, 2013;11(0):236.
Species: Human
Sample Type: Serum
A randomized controlled trial of multicomponent exercise in older adults withmild cognitive impairment.
Authors: Suzuki T, Shimada H, Makizako H, Doi T, Yoshida D, Ito K, Shimokata H, Washimi Y, Endo H, Kato T
PLoS ONE, 2013;8(4):e61483.
Species: Human
Sample Type: Serum
Authors: Suzuki T, Shimada H, Makizako H, Doi T, Yoshida D, Ito K, Shimokata H, Washimi Y, Endo H, Kato T
PLoS ONE, 2013;8(4):e61483.
Species: Human
Sample Type: Serum
Fcgamma receptor-induced soluble vascular endothelial growth factor receptor-1 (VEGFR-1) production inhibits angiogenesis and enhances efficacy of anti-tumor antibodies.
Authors: Justiniano S, Elavazhagan S, Fatehchand K, Shah P, Mehta P, Roda J, Mo X, Cheney C, Hertlein E, Eubank T, Marsh C, Muthusamy N, Butchar J, Byrd J, Tridandapani S
J Biol Chem, 2013;288(37):26800-9.
Species: Human
Sample Type: Cell Culture Supernates
Authors: Justiniano S, Elavazhagan S, Fatehchand K, Shah P, Mehta P, Roda J, Mo X, Cheney C, Hertlein E, Eubank T, Marsh C, Muthusamy N, Butchar J, Byrd J, Tridandapani S
J Biol Chem, 2013;288(37):26800-9.
Species: Human
Sample Type: Cell Culture Supernates
Cardiac angiogenic imbalance leads to peripartum cardiomyopathy.
Authors: Patten IS, Rana S, Shahul S, Rowe GC, Jang C, Liu L, Hacker MR, Rhee JS, Mitchell J, Mahmood F, Hess P, Farrell C, Koulisis N, Khankin EV, Burke SD, Tudorache I, Bauersachs J, del Monte F, Hilfiker-Kleiner D, Karumanchi SA, Arany Z
Nature, 2012;485(7398):333-8.
Species: Human
Sample Type: Plasma
Authors: Patten IS, Rana S, Shahul S, Rowe GC, Jang C, Liu L, Hacker MR, Rhee JS, Mitchell J, Mahmood F, Hess P, Farrell C, Koulisis N, Khankin EV, Burke SD, Tudorache I, Bauersachs J, del Monte F, Hilfiker-Kleiner D, Karumanchi SA, Arany Z
Nature, 2012;485(7398):333-8.
Species: Human
Sample Type: Plasma
Phase I and pharmacokinetic study of sunitinib in pediatric patients with refractory solid tumors: a children's oncology group study.
Authors: Dubois SG, Shusterman S, Ingle AM, Ahern CH, Reid JM, Wu B, Baruchel S, Glade-Bender J, Ivy P, Grier HE, Adamson PC, Blaney SM
Clin. Cancer Res., 2011;17(15):5113-22.
Species: Human
Sample Type: Plasma
Authors: Dubois SG, Shusterman S, Ingle AM, Ahern CH, Reid JM, Wu B, Baruchel S, Glade-Bender J, Ivy P, Grier HE, Adamson PC, Blaney SM
Clin. Cancer Res., 2011;17(15):5113-22.
Species: Human
Sample Type: Plasma
In vitro vascular tube formation testing as a tool for treatment individualisation in patients with cervical cancer.
Authors: Landt S, Heidecke H, Korlach S, Reuter C, Schwidde I, Barinoff J, Thill M, Sehouli J, Kummel S
Anticancer Res., 2011;31(8):2609-15.
Species: Human
Sample Type: Serum
Authors: Landt S, Heidecke H, Korlach S, Reuter C, Schwidde I, Barinoff J, Thill M, Sehouli J, Kummel S
Anticancer Res., 2011;31(8):2609-15.
Species: Human
Sample Type: Serum
Prognostic significance of angiogenic factors in uterine cervical cancer.
Authors: Landt S, Wehling M, Heidecke H, Jeschke S, Korlach S, Stoblen F, Schmid P, Blohmer JU, Lichtenegger W, Sehouli J, Kummel S
Anticancer Res., 2011;31(8):2589-95.
Species: Human
Sample Type: Serum
Authors: Landt S, Wehling M, Heidecke H, Jeschke S, Korlach S, Stoblen F, Schmid P, Blohmer JU, Lichtenegger W, Sehouli J, Kummel S
Anticancer Res., 2011;31(8):2589-95.
Species: Human
Sample Type: Serum
Expression and prognostic value of circulating angiogenic cytokines in pancreatic cancer.
Authors: Rahbari NN, Schmidt T, Falk CS, Hinz U, Herber M, Bork U, Buchler MW, Weitz J, Koch M
BMC Cancer, 2011;11(0):286.
Species: Human
Sample Type: Serum
Authors: Rahbari NN, Schmidt T, Falk CS, Hinz U, Herber M, Bork U, Buchler MW, Weitz J, Koch M
BMC Cancer, 2011;11(0):286.
Species: Human
Sample Type: Serum
Effect of smoking on circulating angiogenic factors in high risk pregnancies.
Authors: Jeyabalan A, Powers RW, Clifton RG, Van Dorsten P, Hauth JC, Klebanoff MA, Lindheimer MD, Sibai B, Landon M, Miodovnik M, Caritis S, Roberts JM, Kuller J, Cotroneo M, Kamon T, Mercer B, Ramsey R, Paul R, Rabello Y, McCart D, Mueller E, Goldenberg R, Copper R, Sorokin Y, Norman G, Millinder A, Christmas JT, McCoy S, Elder S, Elder N, Carter B, Pemberton V, Thurnau G, Meier A, Minton V, Meis P, Swain M, Moawad AH, Jones P, Iams JD, Meadows S, Brenner S, Collins B, Newman RB, Carter SG, Romero R, Sabo V, Thom E, Bain RP, MacPherson C, Johnson D, Fischer ML, McNellis D, Spong C, Catz C, Yaffe S
PLoS ONE, 2010;5(10):e13270.
Species: Human
Sample Type: Serum
Authors: Jeyabalan A, Powers RW, Clifton RG, Van Dorsten P, Hauth JC, Klebanoff MA, Lindheimer MD, Sibai B, Landon M, Miodovnik M, Caritis S, Roberts JM, Kuller J, Cotroneo M, Kamon T, Mercer B, Ramsey R, Paul R, Rabello Y, McCart D, Mueller E, Goldenberg R, Copper R, Sorokin Y, Norman G, Millinder A, Christmas JT, McCoy S, Elder S, Elder N, Carter B, Pemberton V, Thurnau G, Meier A, Minton V, Meis P, Swain M, Moawad AH, Jones P, Iams JD, Meadows S, Brenner S, Collins B, Newman RB, Carter SG, Romero R, Sabo V, Thom E, Bain RP, MacPherson C, Johnson D, Fischer ML, McNellis D, Spong C, Catz C, Yaffe S
PLoS ONE, 2010;5(10):e13270.
Species: Human
Sample Type: Serum
Soluble fms-Like tyrosine kinase 1 (sFlt1), endoglin and placental growth factor (PlGF) in preeclampsia among high risk pregnancies.
Authors: Powers RW, Jeyabalan A, Clifton RG
PLoS ONE, 2010;5(10):e13263.
Species: Human
Sample Type: Serum
Authors: Powers RW, Jeyabalan A, Clifton RG
PLoS ONE, 2010;5(10):e13263.
Species: Human
Sample Type: Serum
An automated method for the determination of the sFlt-1/PIGF ratio in the assessment of preeclampsia.
Authors: Verlohren S, Galindo A, Schlembach D, Zeisler H, Herraiz I, Moertl MG, Pape J, Dudenhausen JW, Denk B, Stepan H
Am. J. Obstet. Gynecol., 2010;202(2):161.e1-161.e1.
Species: Human
Sample Type: Serum
Authors: Verlohren S, Galindo A, Schlembach D, Zeisler H, Herraiz I, Moertl MG, Pape J, Dudenhausen JW, Denk B, Stepan H
Am. J. Obstet. Gynecol., 2010;202(2):161.e1-161.e1.
Species: Human
Sample Type: Serum
Soluble Flt-1 gene therapy ameliorates albuminuria but accelerates tubulointerstitial injury in diabetic mice.
Authors: Kosugi T, Nakayama T, Li Q, Chiodo VA, Zhang L, Campbell-Thompson M, Grant M, Croker BP, Nakagawa T
Am. J. Physiol. Renal Physiol., 2010;298(3):F609-16.
Species: Human
Sample Type: Urine
Authors: Kosugi T, Nakayama T, Li Q, Chiodo VA, Zhang L, Campbell-Thompson M, Grant M, Croker BP, Nakagawa T
Am. J. Physiol. Renal Physiol., 2010;298(3):F609-16.
Species: Human
Sample Type: Urine
Periodic assessment of plasma sFlt-1 and PlGF concentrations and its association with placental morphometry in gestational hypertension (GH) - a prospective follow-up study.
Authors: Jeevaratnam K, Nadarajah VD, Judson JP
BMC Pregnancy Childbirth, 2010;10(0):58.
Species: Human
Sample Type: Plasma
Authors: Jeevaratnam K, Nadarajah VD, Judson JP
BMC Pregnancy Childbirth, 2010;10(0):58.
Species: Human
Sample Type: Plasma
Signs of reduced angiogenic activity after surgical removal of deeply infiltrating endometriosis.
Authors: Bourlev V, Iljasova N, Adamyan L, Larsson A, Olovsson M
Fertil. Steril., 2010;94(1):52-7.
Species: Human
Sample Type: Serum
Authors: Bourlev V, Iljasova N, Adamyan L, Larsson A, Olovsson M
Fertil. Steril., 2010;94(1):52-7.
Species: Human
Sample Type: Serum
Antiangiogenic gene therapy with soluble VEGFR-1, -2, and -3 reduces the growth of solid human ovarian carcinoma in mice.
Authors: Sallinen H, Anttila M, Narvainen J, Koponen J, Hamalainen K, Kholova I, Heikura T, Toivanen P, Kosma VM, Heinonen S, Alitalo K, Yla-Herttuala S
Mol. Ther., 2009;17(2):278-84.
Species: Human
Sample Type: Plasma
Authors: Sallinen H, Anttila M, Narvainen J, Koponen J, Hamalainen K, Kholova I, Heikura T, Toivanen P, Kosma VM, Heinonen S, Alitalo K, Yla-Herttuala S
Mol. Ther., 2009;17(2):278-84.
Species: Human
Sample Type: Plasma
Are plasma VEGF and its soluble receptor sFlt-1 atherogenic risk factors?Cross-sectional data from the SAPHIR study.
Authors: Sandhofer A, Tatarczyk T, Kirchmair R, Iglseder B, Paulweber B, Patsch JR, Schratzberger P
Atherosclerosis, 2009;206(1):265-9.
Species: Human
Sample Type: Plasma
Authors: Sandhofer A, Tatarczyk T, Kirchmair R, Iglseder B, Paulweber B, Patsch JR, Schratzberger P
Atherosclerosis, 2009;206(1):265-9.
Species: Human
Sample Type: Plasma
Pre-eclampsia, soluble fms-like tyrosine kinase 1, and the risk of reduced thyroid function: nested case-control and population based study.
Authors: Levine RJ, Vatten LJ, Horowitz GL
BMJ, 2009;339(0):b4336.
Species: Human
Sample Type: Serum
Authors: Levine RJ, Vatten LJ, Horowitz GL
BMJ, 2009;339(0):b4336.
Species: Human
Sample Type: Serum
Plasma levels of soluble Tie2 and vascular endothelial growth factor distinguish critical limb ischemia from intermittent claudication in patients with peripheral arterial disease.
Authors: Findley CM, Mitchell RG, Duscha BD, Annex BH, Kontos CD
J. Am. Coll. Cardiol., 2008;52(5):387-93.
Species: Human
Sample Type: Plasma
Authors: Findley CM, Mitchell RG, Duscha BD, Annex BH, Kontos CD
J. Am. Coll. Cardiol., 2008;52(5):387-93.
Species: Human
Sample Type: Plasma
Regulation of vascular endothelial growth factor-A and its soluble receptor sFlt-1 by luteinizing hormone in vivo: implication for ovarian follicle angiogenesis.
Authors: Gutman G, Barak V, Maslovitz S, Amit A, Lessing JB, Geva E
Fertil. Steril., 2008;89(4):922-6.
Species: Human
Sample Type: Serum
Authors: Gutman G, Barak V, Maslovitz S, Amit A, Lessing JB, Geva E
Fertil. Steril., 2008;89(4):922-6.
Species: Human
Sample Type: Serum
Natural selection of FLT1 alleles and their association with malaria resistance in utero.
Authors: Muehlenbachs A, Fried M, Lachowitzer J, Mutabingwa TK, Duffy PE
Proc. Natl. Acad. Sci. U.S.A., 2008;105(38):14488-91.
Species: Human
Sample Type: Cell Culture Supernates
Authors: Muehlenbachs A, Fried M, Lachowitzer J, Mutabingwa TK, Duffy PE
Proc. Natl. Acad. Sci. U.S.A., 2008;105(38):14488-91.
Species: Human
Sample Type: Cell Culture Supernates
Cigarette smoke exposure and angiogenic factors in pregnancy and preeclampsia.
Authors: Jeyabalan A, Powers RW, Durica AR, Harger GF, Roberts JM, Ness RB
Am. J. Hypertens., 2008;21(8):943-7.
Species: Human
Sample Type: Plasma
Authors: Jeyabalan A, Powers RW, Durica AR, Harger GF, Roberts JM, Ness RB
Am. J. Hypertens., 2008;21(8):943-7.
Species: Human
Sample Type: Plasma
Angiogenesis markers (VEGF, soluble receptor of VEGF and angiopoietin-1) in very early arthritis and their association with inflammation and joint destruction.
Authors: Clavel G, Bessis N, Lemeiter D, Fardellone P, Mejjad O, Menard JF, Pouplin S, Boumier P, Vittecoq O, Le Loet X, Boissier MC
Clin. Immunol., 2007;124(2):158-64.
Species: Human
Sample Type: Serum
Authors: Clavel G, Bessis N, Lemeiter D, Fardellone P, Mejjad O, Menard JF, Pouplin S, Boumier P, Vittecoq O, Le Loet X, Boissier MC
Clin. Immunol., 2007;124(2):158-64.
Species: Human
Sample Type: Serum
Significant decrease in angiopoietin-1 and angiopoietin-2 after radical prostatectomy in prostate cancer patients.
Authors: Caine GJ, Ryan P, Lip GY, Blann AD
Cancer Lett., 2007;251(2):296-301.
Species: Human
Sample Type: Plasma
Authors: Caine GJ, Ryan P, Lip GY, Blann AD
Cancer Lett., 2007;251(2):296-301.
Species: Human
Sample Type: Plasma
Changes in plasma vascular endothelial growth factor, angiopoietins, and their receptors following surgery for breast cancer.
Authors: Caine GJ, Stonelake PS, Lip GY, Blann AD
Cancer Lett., 2007;248(1):131-6.
Species: Human
Sample Type: Plasma
Authors: Caine GJ, Stonelake PS, Lip GY, Blann AD
Cancer Lett., 2007;248(1):131-6.
Species: Human
Sample Type: Plasma
Angiogenic growth factors in maternal and fetal serum in pregnancies complicated by intrauterine growth restriction.
Authors: Wallner W, Sengenberger R, Strick R, Strissel PL, Meurer B, Beckmann MW, Schlembach D
Clin. Sci., 2007;112(1):51-7.
Species: Human
Sample Type: Serum
Authors: Wallner W, Sengenberger R, Strick R, Strissel PL, Meurer B, Beckmann MW, Schlembach D
Clin. Sci., 2007;112(1):51-7.
Species: Human
Sample Type: Serum
Circulating angiogenic factors in preeclampsia, gestational proteinuria, and preeclampsia superimposed on chronic glomerulonephritis.
Authors: Masuyama H, Suwaki N, Nakatsukasa H, Masumoto A, Tateishi Y, Hiramatrsu Y
Am. J. Obstet. Gynecol., 2006;194(2):551-6.
Species: Human
Sample Type: Serum
Authors: Masuyama H, Suwaki N, Nakatsukasa H, Masumoto A, Tateishi Y, Hiramatrsu Y
Am. J. Obstet. Gynecol., 2006;194(2):551-6.
Species: Human
Sample Type: Serum
Soluble endoglin and other circulating antiangiogenic factors in preeclampsia.
Authors: Levine RJ, Lam C, Qian C, Yu KF, Maynard SE, Sachs BP, Sibai BM, Epstein FH, Romero R, Thadhani R, Karumanchi SA
N. Engl. J. Med., 2006;355(10):992-1005.
Species: Human
Sample Type: Serum
Authors: Levine RJ, Lam C, Qian C, Yu KF, Maynard SE, Sachs BP, Sibai BM, Epstein FH, Romero R, Thadhani R, Karumanchi SA
N. Engl. J. Med., 2006;355(10):992-1005.
Species: Human
Sample Type: Serum
Phase I clinical and pharmacokinetic study of PTK/ZK, a multiple VEGF receptor inhibitor, in patients with liver metastases from solid tumours.
Authors: Mross K, Drevs J, Muller M, Medinger M, Marme D, Hennig J, Morgan B, Lebwohl D, Masson E, Ho YY, Gunther C, Laurent D, Unger C
Eur. J. Cancer, 2005;41(9):1291-9.
Species: Human
Sample Type: Serum
Authors: Mross K, Drevs J, Muller M, Medinger M, Marme D, Hennig J, Morgan B, Lebwohl D, Masson E, Ho YY, Gunther C, Laurent D, Unger C
Eur. J. Cancer, 2005;41(9):1291-9.
Species: Human
Sample Type: Serum
Hypoxia-induced increase in soluble Flt-1 production correlates with enhanced oxidative stress in trophoblast cells from the human placenta.
Authors: Li H, Gu B, Zhang Y, Lewis DF, Wang Y
Placenta, 2005;26(2):210-7.
Species: Human
Sample Type: Cell Culture Supernates
Authors: Li H, Gu B, Zhang Y, Lewis DF, Wang Y
Placenta, 2005;26(2):210-7.
Species: Human
Sample Type: Cell Culture Supernates
Urinary placental growth factor and risk of preeclampsia.
Authors: Levine RJ, Thadhani R, Qian C, Lam C, Lim KH, Yu KF, Blink AL, Sachs BP, Epstein FH, Sibai BM, Sukhatme VP, Karumanchi SA
JAMA, 2005;293(1):77-85.
Species: Human
Sample Type: Urine
Authors: Levine RJ, Thadhani R, Qian C, Lam C, Lim KH, Yu KF, Blink AL, Sachs BP, Epstein FH, Sibai BM, Sukhatme VP, Karumanchi SA
JAMA, 2005;293(1):77-85.
Species: Human
Sample Type: Urine
Urinary angiogenic factors cluster hypertensive disorders and identify women with severe preeclampsia.
Authors: Buhimschi CS, Norwitz ER, Funai E, Richman S, Guller S, Lockwood CJ, Buhimschi IA
Am. J. Obstet. Gynecol., 2005;192(3):734-41.
Species: Human
Sample Type: Urine
Authors: Buhimschi CS, Norwitz ER, Funai E, Richman S, Guller S, Lockwood CJ, Buhimschi IA
Am. J. Obstet. Gynecol., 2005;192(3):734-41.
Species: Human
Sample Type: Urine
GM-CSF induces expression of soluble VEGF receptor-1 from human monocytes and inhibits angiogenesis in mice.
Authors: Eubank TD, Roberts R, Galloway M, Wang Y, Cohn DE, Marsh CB
Immunity, 2004;21(6):831-42.
Species: Human
Sample Type: Cell Culture Supernates
Authors: Eubank TD, Roberts R, Galloway M, Wang Y, Cohn DE, Marsh CB
Immunity, 2004;21(6):831-42.
Species: Human
Sample Type: Cell Culture Supernates
Circulating angiogenic factors and the risk of preeclampsia.
Authors: Levine RJ, Maynard SE, Qian C, Lim KH, England LJ, Yu KF, Schisterman EF, Thadhani R, Sachs BP, Epstein FH, Sibai BM, Sukhatme VP, Karumanchi SA
N. Engl. J. Med., 2004;350(7):672-83.
Species: Human
Sample Type: Serum
Authors: Levine RJ, Maynard SE, Qian C, Lim KH, England LJ, Yu KF, Schisterman EF, Thadhani R, Sachs BP, Epstein FH, Sibai BM, Sukhatme VP, Karumanchi SA
N. Engl. J. Med., 2004;350(7):672-83.
Species: Human
Sample Type: Serum
Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia.
Authors: Maynard SE, Min JY, Merchan J, Lim KH, Mondal S, Stillman IE, Epstein FH, Karumanchi SA
J. Clin. Invest., 2003;111(5):649-58.
Species: Human
Sample Type: Serum
Authors: Maynard SE, Min JY, Merchan J, Lim KH, Mondal S, Stillman IE, Epstein FH, Karumanchi SA
J. Clin. Invest., 2003;111(5):649-58.
Species: Human
Sample Type: Serum
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