抗SOD1 [6F5]抗体 | Anti-SOD1 [6F5] antibody

• 特長
• 価格
• DATA IMAGES
• 製品情報
• APPLICATION
• PROPERTIES
• TARGET
• REFERENCEE(抜粋)

特長

• 高品質の抗体です。
• 幅広い研究分野に関連する抗体を取り揃えています。
• 使用されたアプリケーションや動物種などの情報が充実しています。
• 多数の論文で使用実績がある信頼性の高い抗体です。

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価格

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DATA IMAGES

	ICC/IF analysis of 3T3-L1 cells using GTX83012 SOD1 antibody [6F5].Green : SOD1 Blue: DRAQ5 fluorescent DNA dye
	WB analysis of HeLa (1), NIH3T3 (2), A549 (3) and A431 (4) cell lysate using GTX83012 SOD1 antibody [6F5].
	ICC/IF analysis of PANC-1 (left) and SKBR-3 (right) cells using GTX83012 SOD1 antibody [6F5].Green : SOD1 Blue: DRAQ5 fluorescent DNA dye Red: Actin filaments
	FACS analysis of A431 cells using GTX83012 SOD1 antibody [6F5].Green : SOD1 Purple : negative control

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製品情報

Host	Mouse
Clonality	Monoclonal
Clone Name	6F5
Isotype	IgG1
Application	WB, ICC/IF, FACS, ELISA
Reactivity	Human, Mouse

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APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Dilution
WB	1/500 - 1/2000
ICC/IF	1/200 - 1/1000
FACS	1/200 - 1/400
ELISA	1/10000

Not tested in other applications.

Calculated MW	16 kDa. ( Note )

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PROPERTIES

Form	Liquid
Buffer	Ascites, 0.03% sodium azide
Storage	Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Antigen Species	Human
Immunogen	Purified recombinant fragment of human SOD1 expressed in E. Coli.
Purification	Unpurified
Conjugation	Unconjugated
Note	For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

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TARGET

Synonyms	superoxide dismutase 1 , ALS , ALS1 , HEL-S-44 , IPOA , SOD , hSod1 , homodimer
Cellular Localization	Cytoplasm,Mitochondrion,Nucleus
Background	The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene. [provided by RefSeq, Jul 2008]
Database	・ Gene ID: 6647 SOD1 ・ UniProt: P00441 SOD1

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REFERENCEE(抜粋)

Application Reference	Application/Reactivity
Hathaway CK et al. Proc Natl Acad Sci U S A 2015; 112 (16) : 1183904 Endothelin-1 critically influences cardiac function via superoxide-MMP9 cascade.	Application : WB Reactivity : Mouse

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