抗TCR V alpha 2 [F1] (FITC)抗体 | Anti-TCR V alpha 2 [F1] (FITC) antibody

• 特長
• 価格
• DATA IMAGES
• 製品情報
• APPLICATION
• PROPERTIES
• TARGET

特長

• 高品質の抗体です。
• 幅広い研究分野に関連する抗体を取り揃えています。
• 使用されたアプリケーションや動物種などの情報が充実しています。
• 多数の論文で使用実績がある信頼性の高い抗体です。

目次に戻る

価格

目次に戻る

DATA IMAGES

FACS analysis of positive MOLT16 cells (left panel) or negative control HPB-ALL cells (right panel) using GTX79225 TCR V alpha 2 antibody [F1] (FITC). Dilution : 5ul of primary antibody were used per test

目次に戻る

製品情報

Host	Mouse
Clonality	Monoclonal
Clone Name	F1
Isotype	IgG2a
Application	WB, FACS, IHC
Reactivity	Human, Primate

目次に戻る

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Dilution
WB	Assay dependent
FACS	1-2 μg/test
IHC	Assay dependent

Not tested in other applications.

目次に戻る

PROPERTIES

Form	Liquid
Buffer	PBS, 0.5% BSA, 0.1% sodium azide
Storage	Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. Protect from light.
Concentration	0.15 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species	Human
Immunogen	Human TCR V alpha-2
Purification	Protein A purified
Conjugation	Fluorescein isothiocyanate (FITC)
Note	For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

目次に戻る

TARGET

Synonyms	T cell receptor alpha variable 2 , TCRAV11S1 , TCRAV2S1
Background	T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface of antigen presenting cells (APC). Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. In a single cell, the T cell receptor loci are rearranged and expressed in the order delta, gamma, beta, and alpha. If both delta and gamma rearrangements produce functional chains, the cell expresses delta and gamma. If not, the cell proceeds to rearrange the beta and alpha loci. This region represents the germline organization of the T cell receptor alpha and delta loci. Both the alpha and delta loci include V (variable), J (joining), and C (constant) segments and the delta locus also includes diversity (D) segments. The delta locus is situated within the alpha locus, between the alpha V and J segments. During T cell development, the delta chain is synthesized by a recombination event at the DNA level joining a D segment with a J segment; a V segment is then joined to the D-J gene. The alpha chain is synthesized by recombination joining a single V segment with a J segment. For both chains, the C segment is later joined by splicing at the RNA level. Recombination of many different V segments with several J segments provides a wide range of antigen recognition. Additional diversity is attained by junctional diversity, resulting from the random additional of nucleotides by terminal deoxynucleotidyltransferase. Five variable segments can be used in either alpha or delta chains and are described by TRAV/DV symbols. Several V and J segments of the alpha locus are known to be incapable of encoding a protein and are considered pseudogenes. [provided by RefSeq, Aug 2016]
Database	・ Gene ID: 28691 TRAV2

目次に戻る