Urinary Diacetylspermidine ELISA Kit
Date:August 28 2017Web Page No:80875
A new cancer marker
Urinary Diacetylspermine/Diacetylspermidine ELISA kit
N1,N12-Diacetylspermine (DiAcSpm)
N1,N8-Diacetylspermidine (DiAcSpd)
Polyamines are generally believed to function both in protein synthesis and DNA synthesis leading to control cell proliferation. In 1971, it was reported that total amount of urinary polyamines elevated in cancer patients. Quantitative kits of urinary polyamines were already developed and utilized as a general biochemical examination.
Recently two diacetyl-derivatives, N1, N12-diacetylspermine (DiAcSpm) and N1, N8-diacetylspermidine (DiAcSpd), were found to be excreted in urine and form 0.6% and 1.4% of total polyamines respectively.
Comparing urine of diseased person with that of healthy person, some reports suggested a possibility that diacetyl-derivatives correlate to the status of disease more closely than total amount of polyamines.
Our ELISA kits are convenient to quantify urinary DiAcSpm or DiAcSpd.
Synthetic Pathway of DiAcSpm and DiAcSpd
Assay Principle
Specs
#KK073 Urinary N1, N12-diacetylspermine (DiAcSpm) ELISA kit
Standard Curve Range : 6.25 - 200 nM
Detection Limit : 12.5 nM
Minimum Sample Dilution : x 4
Sample : Urine
#KK123 Urinary N1, N8-diacetylspermidine (DiAcSpd) ELISA kit
Standard Curve Range : 9.375 - 600 nM
Detection Limit : 18.75 nM
Minimum Sample Dilution : x 2
Sample : Urine
[Date : February 15 2024 12:37]
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[Date : February 15 2024 12:37]
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