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New mitochondria uncoupling agent Ppc-1

Date:December 22 2017Web Page No:80714

Funakoshi Co.,Ltd.

Increasing mitochondria's oxigen consumption without inhibiting ATP synthesis
Ppc-1, MitoUncoupler

Ppc-1 is a newly isolated molecule from Polysphondylium pseudo-candidum. It shows comparatively mild uncoupling activity in Mitochodria.

Ppc-1 is a newly isolated molecule from Polysphondylium pseudo-candidum.
It shows comparatively mild uncoupling activity in Mitochodria.

According to papers, following effects are reported in Ppc-1.

  • Ppc-1 stimulates oxygen consumption without inhibiting ATP synthesis in mitochondria, isolated from mouse liver. 1), 2)
  • Ppc-1 administrated mouse shows inhibition of weight gain, without affecting liver and kidney. 1), 2)
  • Cell proliferation is inhibited without inducing cell death, in Ppc-1 treated 3T3-L1 cells. 3)

Features

  • Comparatively mild uncoupling activity
  • Low effect on ATP synthesis or degradation
  • Low active oxygen generation
  • Low cytotoxicity
  • Cell proliferation is inhibited by adding Ppc-1 to culture medium.
  • Chemical Name :3-Methylbut-2-enyl 4-methoxy-8-(3-methylbut-2-enyloxy)quinoline-2-carboxylate
  • CAS number :1245818-17-0
  • Molecular Formula :C21H25NO4
  • Molecular Weight :355.43
  • Purity :≧98%
  • Soluble in DMSO

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Reference

[Date : December 15 2018 00:15]

Detail Product Name Product Code Supplier Size Price
Ppc-1, MitoUncoupler
Datasheet
FDV-0011 FNAFunakoshi Co.,Ltd. 5 mg $200

Description Ppc-1 is a newly isolated molecule from Polysphondylium pseudo-candidum. It shows comparatively mild uncoupling activity in Mitochodria.
Storage -20°C CAS 1245818-17-0
Link

[Date : December 15 2018 00:15]

Ppc-1, MitoUncoupler


  • Product Code: FDV-0011
  • Supplier: FNA
  • Size: 5mg
  • Price: $200

Description Ppc-1 is a newly isolated molecule from Polysphondylium pseudo-candidum. It shows comparatively mild uncoupling activity in Mitochodria.
Storage -20°C CAS 1245818-17-0
Link

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