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A natural bioactive compound with antibacterial, and antiviral activities Amidinomycin (Sulfate) [CAS: 74984-58-0]

Date:July 02 2026Web Page No:549085

Amidinomycin is a small molecular bioactive compound isolated from Streptomyces flavochromogenes, and it is a polypeptide compound with an amidine group at the terminal. In 1960, Dr. Nakamura and Dr. Umezawa’s group reported that this compound exhibited activity against spore-forming bacteria such as B. subtilis and B. megatherium.1) In 1961, subsequent studies indicated that myxoviromycin2, 3) which was reported with anti-influenza virus activity and amidinomcyin were the same compound.4, 5)

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Amidinomycin-Structure

Chemical structure of amidinomycin (Sulfate) (#20414)


Specification

CAS#74984-58-0
Molecular FormulaC9H18N4O•H2SO4
Molecular Weight 296.342
Purity>90% (HPLC)
SolubilitySoluble in H2O

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Application Notes

• Amidinomycin exhibited antibacterial activity against B. subtilis and B. megaterium.1)

Bacterial species IC50(μg/ml)
B. subtilis 5
B. megaterium APF 10
E. coli >320

• Amidinomycin exhibited antiviral activity against influenza viruses.3)

Virus species Strain name MIC (μg/ml)
Influenza A PR8 8.8
FM1 1.7
Influenza B Zee 1.7

* Biological activity of the product was not verified. The values shown above were cited from the references.


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Reference

  1. Nakamura S., et al., J. Antibiot. Ser. A, 14(2), 103-106(1961). [DOI:10.11554/antibioticsa.14.2_103]
  2. Kuroya M., et al., Japan. J. Microb., 1(2), 85-90(1957). [PMID:13549116]
  3. Kobayashi N., Tohoku J. Exp. Med., 70(1), 95-102(1959). [PMID:14410278]
  4. Nakamura S., et al., J. Antibiot. Ser. A, 14(3), 163-164(1961). [DOI:10.11554/antibioticsa.14.3_163]
  5. Kaneda M., et al., J. Antibiot., 33(7), 778-780(1980). [PMID:7410224]

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Product Information

[Date : July 04 2026 00:09]

Detail Product Name Product Code Supplier Size Price
Amidinomycin (sulfate), Antibacterial, Antiviral
DatasheetThis may not be the latest data sheet.
20414 IMCInstitute of Microbial Chemistry 1 mg $500

Description M.W.: 296.342 Purity : >90% (HPLC) Molecular Formula : C9H18N4O•H2SO4 Solubility : Soluble in H2O, Amidinomycin is a natural bioactive compound with antibacterial and antiviral activities.
Storage CAS 74984-58-0
Link

[Date : July 04 2026 00:09]

Amidinomycin (sulfate), Antibacterial, Antiviral


  • Product Code: 20414
  • Supplier: IMC
  • Size: 1mg
  • Price: $500

Description M.W.: 296.342 Purity : >90% (HPLC) Molecular Formula : C9H18N4O•H2SO4 Solubility : Soluble in H2O, Amidinomycin is a natural bioactive compound with antibacterial and antiviral activities.
Storage CAS 74984-58-0
Link


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