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Bioactive compound harboring activities of tyrosine hydroxylase inhibition, phenylalanine hydroxylase inhibition, and hypotensive Oudenone (Potassium Salt)

Date:July 08 2025Web Page No:520094

Oudenone was isolated from fermentation broth of Oudemansiella radicata (also known as Hymenopellis radicata) as an inhibitor of tyrosine hydroxylase (IC50: 1.1x10-4 M).1, 2)
It also inhibited phenylalanine hydroxylase (IC50: 2.3×10-3 M)3) and showed strong hypotensive effect.1)
* This product is for research use only.


Oudenone-Structure

Structure of Oudenone (Potassium Salt) ( #16640)


Specification

CAS#34200-97-0 *
Molecular FormulaC12H17O4K
Molecular Weight 264.362
Purity>98% (HPLC)
SolubilitySoluble in DMSO and H2O
* This CAS# is not reflected 3D structure of the hydroxyl group.

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Application Note

  • It was reported that this compound inhibited tyrosine hydroxylase (IC50: 1.1x10-4 M) and phenylalanine hydroxylase (IC50: 2.3x10-3 M).
  • This compound also indicated strong hypotensive effect.

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Reference

  1. Umezawa, H., et al., J. Antibiotics, 23 (10), 514~518 (1970). [PMID:4991641]
  2. Ohno, M., et al., J. Am. Chem. Soc., 93 (5), 1285~1286 (1971). [PMID:5545929]
  3. Koizumi, S., et al., J. Antibiotics, 35 (4), 458~462 (1982). [PMID:7096201]

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Product Information

[Date : July 15 2025 00:07]

Detail Product Name Product Code Supplier Size Price
Oudenone(potassium salt), Tyrosine hydroxylase inhibitor, Hypotensive
DatasheetThis may not be the latest data sheet.
16640 IMCInstitute of Microbial Chemistry 1 mg $500

Description M.W.: 264.362 Purity : >98% (HPLC) Molecular Formula : C12H17O4・K Solubility : Soluble in H2O, and DMSO, Oudenone is a bioactive compound harboring activities of tyrosine hydroxylase inhibition, phenylalanine inhibition, and hypotensive effect.
Storage -20°C CAS 34200-97-0 (assigned to the planar structure of oudenone potassium salt)
Link

[Date : July 15 2025 00:07]

Oudenone(potassium salt), Tyrosine hydroxylase inhibitor, Hypotensive


  • Product Code: 16640
  • Supplier: IMC
  • Size: 1mg
  • Price: $500

Description M.W.: 264.362 Purity : >98% (HPLC) Molecular Formula : C12H17O4・K Solubility : Soluble in H2O, and DMSO, Oudenone is a bioactive compound harboring activities of tyrosine hydroxylase inhibition, phenylalanine inhibition, and hypotensive effect.
Storage -20°C CAS 34200-97-0 (assigned to the planar structure of oudenone potassium salt)
Link


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