How to search

HOME> Products> Antibody> Innovative Antibodies for Challenging Antigens

Empowering your Research in Oncology & Structural Analysis Innovative Antibodies for Challenging Antigens

Date：May 13 2026Web Page No：160819

Perseus Proteomics Inc.

Perseus Proteomics Inc. offers a wide range of cancer-related antibodies.

＊The products are for research use only.

What is S1P

Sphingosine-1-phosphate (S1P) is a lipid signaling molecule that regulates various physiological functions via its receptors, including the trafficking of cancer-related immune cells, vascular permeability, and angiogenesis. In research targeting the S1P receptor S1PR3, X-ray crystallography has elucidated the three-dimensional structure recognized by S1P by focusing on its localization in the cell membrane and binding to the extracellular domain.


Go back to index

What is GPR87

In recent years, GPR87 has emerged as a promising therapeutic target and cancer marker, as it is expressed in various types of cancer while showing minimal expression in normal tissues 1. Research using humanized antibodies, derived from anti-GPR87 mouse monoclonal antibodies, has demonstrated the efficacy of GPR87-targeted near-infrared photoimmunotherapy in models of lung cancer and malignant pleural mesothelioma 2.

GPR87 antibody IHC
Paraffin section of human esophagus

Reference

  1. Bai, R., et al., Commun. Biol., 5(1), 663(2022). [PMID:35790819]
  2. Yasui, H., et al., EBioMedicine, 67, 103372(2021). [PMID:33993055]

Go back to index

Lineup

Name Host Species (Clonality) Clone Code
EDG3/S1PR3 antibody Mouse (Monoclonal) AS055 PP-AS55-0C
GPR87 antibody Mouse (Monoclonal) C0804 PP-C0804-0C
GPR87 antibody Mouse (Monoclonal) C0812 PP-C0812-0C

Go back to index

Example of Use

EDG3/S1PR3 antibody (PP-AS55-0C)

Flow Cytometry ; Anti human EDG3/S1PR3 mouse monoclonal antibody/ AS55

Two experimental groups were prepared using the human breast cancer cell line Cama-1: an S1PR3-targeted siRNA group (siRNA-S1PR3 group) and a negative control siRNA group. Knockdown efficiency was evaluated by qPCR, with relative expression levels calculated using the 2-ΔΔCt method. The results showed that S1PR3 expression was significantly reduced in the siRNA-S1PR3 group compared to the negative control group. Additionally, the specificity of antibody staining was assessed via flow cytometry.

Citation: Maeda, S., et al., Sci. Adv., 7(24), eabf5325(2021)


GPR87 antibody (PP-C0804-0C, PP-C0812-0C)

Flow Cytometry GPR87 antibody

GPR87-overexpressing cells (2×105 cells) were incubated with the primary antibody at a final concentration of 1 μg/mL for 1 hour. After washing, PE-labeled anti-mouse IgG (secondary antibody: Jackson ImmunoResearch Laboratories, 1:200) was added, and the cells were incubated for 1 hour at 4°C in the dark. After a final wash, the cells were analyzed using a flow cytometer. A peak shift was confirmed at the final concentration of 1 μg/mL.

Citation: Niwa, S., (2011) Doctoral thesis (Japanese)


Go back to index

Product Information

[Date : May 13 2026 00:11]

Detail Product Name Product Code Supplier Size Price
Anti-human EDG3/S1PR3 mouse monoclonal antibody (ProteinA purified), 1 mg/mL
DatasheetThis may not be the latest data sheet. 		PP-AS55-0C PMXPerseus Proteomics Inc. 100 µl $870

Description Clone: AS55, Formulation: Physiologic saline with 0.1 % NaN3, Purification: Affinity chromatography with Protein A, S1PR3 (Sphingosine-1-phosphate receptor 3) is a G protein-coupled receptor (GPCR) widely expressed in the central nervous system and vascular tissues, regulating cell migration, angiogenesis, and neuroprotection via sphingosine-1-phosphate (S1P) signaling. It modulates immune responses and vascular permeability. Dysregulation is linked to inflammatory diseases, neurodegeneration, and vascular disorders.
Storage -20°C
Antigen Species Host Species Class Label
Cross Reactivity Application FCM
Clonality Format Purification Absorption
Link

Anti-human GPR87 mouse monoclonal antibody(C0804), ProteinA purified, 1mg/mL
DatasheetThis may not be the latest data sheet. 		PP-C0804-0C PMXPerseus Proteomics Inc. 100 µl $870

Description Formulation: Physiologic saline with 0.1 % NaN3, Purification: Affinity chromatography with Protein A, GPR87 (G protein-coupled receptor 87) is a G proteincoupled receptor (GPCR) primarily expressed in epithelial and tumor cells, where it promotes cell proliferation, survival, and tumor progression. It responds to lysophosphatidic acid (LPA) and is involved in pathways such as JAK2/STAT3 signaling and p53-dependent responses to DNA damage. Aberrations in GPR87 are associated with cancer development, including pancreatic ductal adenocarcinoma (PDA) and other carcinomas.
Storage -20°C
Antigen Species Host Species Class Label
Cross Reactivity Application FCM,IHC,ICC
Clonality Format Purification Absorption
Link

Anti-human GPR87 mouse monoclonal antibody(C0812), ProteinA purified, 1mg/mL
DatasheetThis may not be the latest data sheet. 		PP-C0812-0C PMXPerseus Proteomics Inc. 100 µl $870

Description Formulation: Physiologic saline with 0.1 % NaN3, Purification: Affinity chromatography with Protein A, GPR87 (G protein-coupled receptor 87) is a G proteincoupled receptor (GPCR) primarily expressed in epithelial and tumor cells, where it promotes cell proliferation, survival, and tumor progression. It responds to lysophosphatidic acid (LPA) and is involved in pathways such as JAK2/STAT3 signaling and p53-dependent responses to DNA damage. Aberrations in GPR87 are associated with cancer development, including pancreatic ductal adenocarcinoma (PDA) and other carcinomas.
Storage -20°C
Antigen Species Host Species Mouse Class Label
Cross Reactivity Huma/Mouse Application FCM,IHC,ICC
Clonality Format Purification Absorption
Link

[Date : May 13 2026 00:11]

Anti-human EDG3/S1PR3 mouse monoclonal antibody (ProteinA purified), 1 mg/mL

DatasheetThis may not be the latest data sheet.


  • Product Code: PP-AS55-0C
  • Supplier: PMX
  • Size: 100µl
  • Price: $870

Description Clone: AS55, Formulation: Physiologic saline with 0.1 % NaN3, Purification: Affinity chromatography with Protein A, S1PR3 (Sphingosine-1-phosphate receptor 3) is a G protein-coupled receptor (GPCR) widely expressed in the central nervous system and vascular tissues, regulating cell migration, angiogenesis, and neuroprotection via sphingosine-1-phosphate (S1P) signaling. It modulates immune responses and vascular permeability. Dysregulation is linked to inflammatory diseases, neurodegeneration, and vascular disorders.
Storage -20°C
Antigen Species Host Species
Class Label
Cross Reactivity Application FCM
Clonality Format
Purification Absorption
Link

Anti-human GPR87 mouse monoclonal antibody(C0804), ProteinA purified, 1mg/mL

DatasheetThis may not be the latest data sheet.


  • Product Code: PP-C0804-0C
  • Supplier: PMX
  • Size: 100µl
  • Price: $870

Description Formulation: Physiologic saline with 0.1 % NaN3, Purification: Affinity chromatography with Protein A, GPR87 (G protein-coupled receptor 87) is a G proteincoupled receptor (GPCR) primarily expressed in epithelial and tumor cells, where it promotes cell proliferation, survival, and tumor progression. It responds to lysophosphatidic acid (LPA) and is involved in pathways such as JAK2/STAT3 signaling and p53-dependent responses to DNA damage. Aberrations in GPR87 are associated with cancer development, including pancreatic ductal adenocarcinoma (PDA) and other carcinomas.
Storage -20°C
Antigen Species Host Species
Class Label
Cross Reactivity Application FCM,IHC,ICC
Clonality Format
Purification Absorption
Link

Anti-human GPR87 mouse monoclonal antibody(C0812), ProteinA purified, 1mg/mL

DatasheetThis may not be the latest data sheet.


  • Product Code: PP-C0812-0C
  • Supplier: PMX
  • Size: 100µl
  • Price: $870

Description Formulation: Physiologic saline with 0.1 % NaN3, Purification: Affinity chromatography with Protein A, GPR87 (G protein-coupled receptor 87) is a G proteincoupled receptor (GPCR) primarily expressed in epithelial and tumor cells, where it promotes cell proliferation, survival, and tumor progression. It responds to lysophosphatidic acid (LPA) and is involved in pathways such as JAK2/STAT3 signaling and p53-dependent responses to DNA damage. Aberrations in GPR87 are associated with cancer development, including pancreatic ductal adenocarcinoma (PDA) and other carcinomas.
Storage -20°C
Antigen Species Host Species Mouse
Class Label
Cross Reactivity Huma/Mouse Application FCM,IHC,ICC
Clonality Format
Purification Absorption
Link

Go back to index

CONTACT

export@funakoshi.co.jp

  • ※Prices on our website are for your reference only. Please inquire your distributor for your prices.
  • ※Please note that Product Information or Price may change without notice.