For cancer research : Anti-Human Lumican antibody
Date:June 07 2017Web Page No:160340
Funakoshi Co.,Ltd.
For clear staining of human lumican in Immunohistochemistry (IHC)
Anti-Human Lumican Rabbit-Poly
Lumican is a glycoprotein, consists of 338 amino acids and is a member of small leucine-rich proteoglycan (SLRP) family. Lumican contains tandem leucine-rich repeat region and its central region plays a role in N-linked glycosylation.
It has been reported that overexpression of lumican is related to skin cancer, breast cancer, pancreas cancer, lung cancer, colon cancer, malignant melanoma and bone cancer.
Funakoshi's anti-human lumican rabbit-poly can stain tumor part and stromal component in cancer tissues sharply.
This product is commercialized by the research result of Departments of Pathology and Integrative Oncological Pathology, Nippon Medical School.
Specification
- Immunogen : Synthetic peptide of Human Lumican aa 211-227
- Host : Rabbit
- Crossreactivity : Human and Rat
- Format : Affinity Purified
- Product Form : Phosphate buffered saline (10mM Phosphate buffer, 0.15M NaCl (pH7.2))(0.3mg/ml)
- Preservative : 0.1% Sodium Azide
- Quantity : 25 μL
- Application : Immunohistochemistry (FFPE ; Formalin-Fixed Paraffin-Embedded tissue) and Western Blot
Staining Data
Fig. 1 IHC data of human pancreas cancer tissue (FFPE)
Fig.2 IHC data of human lung cancer tissue (FFPE). Lumican can be detected in cancer cell (Left) or stromal component (Right) at squamous cell cancer.
Fig.3 Western Blotting data of A549 cell lysate. Core protein (~37 kDa) and other bands can be detected by difference of glycosylation.
Fig. 4 IHC data from tissue sample of Bowen's disease patient. Lumican expression is detected in cytoplasm of cancer cells at epidermis.
Fig. 5 IHC data from tissue sample of hidroacanthoma simplex. Lumican expression is detected in cytoplasm of cancer cells at epidermis.
Citation
- Yamamoto, T., et al., Cancer Lett., 320, 31~39 (2012).
- Ishiwata, T., et al., Exp. Mol. Pathol., 88, 363~370 (2010).
- Matsuda, Y., et al., Int. J. Oncol., 33, 1177~1185 (2008).
- Ishiwata, T., et al., Oncol. Rep., 18, 537~543 (2007).
- Seya, T., et al., Oncol. Rep., 16, 1225~1230 (2006).
- Shinji, S., et al., Int. J. Oncol., 26, 873~880 (2005).
- Kusafuka, K., et al., J. Pathol., 203, 953~960 (2004).
- Ishiwata, T., et al., Pathol. Int., 54, 77~81 (2004).
- Saika, S., et al., Invest. Ophthalmol. Vis. Sci., 44, 2094~2102 (2003).
- Naito, Z., et al., Exp. Mol. Pathol., 74, 33~39 (2003).
- Lu, Y. P., et al., Pathol. Int., 52, 519~526 (2002).
- Naito, Z., et al., Int. J. Oncol., 20, 943~948 (2002).
- Onda, M., et al., Exp. Mol. Pathol., 72, 142~149 (2002).
- Ping, Lu. Y., et al., J. Pathol., 196, 324~330 (2002).
- Qin, H., et al., J. Pathol., 195, 604~608 (2001).
- Baba, H., et al., Jpn. Circ. J., 65, 445~450 (2001).
- Takayama, R., et al., Am, J, Dermatopathol., 35, 827~832 (2013).
- Takayama, R., et al., Am, J, Dermatopathol., 36, 655~660 (2014).
- Niiyama, S., et al., Case Rep Dermatol., 7, 241~244 (2015).
[Date : February 15 2024 12:37]
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Anti-Lumican, Human, Rabbit-Poly DatasheetThis may not be the latest data sheet. |
FDV-0001 | FNAFunakoshi Co.,Ltd. | 25 µl | $160 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||
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[Date : February 15 2024 12:37]
Anti-Lumican, Human, Rabbit-Poly
DatasheetThis may not be the latest data sheet.
- Product Code: FDV-0001
- Supplier: FNA
- Size: 25µl
- Price: $160
Description |
Lumican is a glycoprotein, consists of 338 amino acids and is a member of small leucine-rich proteoglycan (SLRP) family. Lumican contains tandem leucine-rich repeat region and its central region plays a role in N-linked glycosylation. It has been reported that overexpression of lumican is related to skin cancer, breast cancer, pancreas cancer, lung cancer, colon cancer, malignant melanoma and bone cancer. Funakoshi's anti-human lumican rabbit-poly can stain tumor part and stromal component in cancer tissues sharply. |
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Storage | -20°C | ||
Antigen Species | Human | Host Species | Rabbit |
Class | Label | Unlabeled | |
Cross Reactivity | Human/Rat | Application | IHC,Western Blot |
Clonality | Format | ||
Purification | Affinity Purified | Absorption | |
Link |
Antibody Product List (0-M) |
CONTACT
export@funakoshi.co.jp
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- ※Please note that Product Information or Price may change without notice.