ATCC®ウェビナーのお知らせ
（エクソソームをはじめとするExtracellular Vesiclesについて）

ATCC®（メーカー略称：ACC）では 2020年2月21日に無料のウェビナーを開催しました。ATCC®Webにて、録画版をご覧になれますので、是非ご覧いただき、皆様の今後のご研究にお役立て下さい。

・演題：Extracellular Vesicles: For Better and For Worse
・演者：Fatah Kashanchi, Ph.D., Professor, George Mason University
　　　　Heather Branscome, M.S., Lead Biologist, ATCC®
・言語：英語
・開催日：2020年2月21日（金）2：00 am（日本時間）（開催済み）

ウェビナーの詳細・録画版のご視聴はこちらから
※ ATCC® Exosomesの詳細はこちら。

Abstract:

Extracellular vesicles (EVs), such as exosomes, are nano-sized particles secreted by all cell types. Because of their ability to transfer a wide variety of biological cargo from donor to recipient cells, EVs have the potential to exert potent effects. Depending on the source of the donor cells, these effects may be either beneficial or harmful to recipient cells. For example, recent advancements in EV purification methods have allowed for the efficient separation of EVs away from virus in virally infected cells. Characterization of these damaging EVs has revealed the presence of viral material, and functional analyses have suggested that these EVs elicit adverse effects in uninfected recipient cells. On the other hand, EVs from human stem cells have demonstrated the ability to contribute to wound healing, angiogenesis, and immunomodulation. Therefore, these reparative EVs hold great promise for the future of regenerative medicine. This webinar will highlight recent research surrounding both damaging EVs from infected cells and reparative EVs from stem cells and discuss their potential applications for diagnostic and therapeutic purposes.

Key Points:

Extracellular vesicles (EVs) such as exosomes are critical mediators of intercellular communication. The diverse biological cargo that is associated with these vesicles is believed to mediate the pleiotropic effects of EVs. Damaging EVs contain viral non-coding RNAs and other viral proteins. These EVs can exert deleterious effects on recipient cells; further characterization of damaging EVs may serve for diagnostic purposes. Reparative EVs can contribute to various biological processes ranging from normal cellular development to the repair of damaged and/or diseased tissue. Because of their broad regenerative properties, stem cell EVs are being evaluated as potential replacements for stem cell therapy.

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