6-keto Prostaglandin F1α MaxSpec Standard | CAS:58962-34-8

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• 製品情報
• 製品詳細
• 文献

価格

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製品情報

6-keto Prostaglandin F_1α (6-keto PGF_1α) is the inactive, non-enzymatic hydrolysis product of PGI₂ (Item No. 18220). 6-keto PGF_1α serves as a useful marker of PGI₂ biosynthesis in vivo. When [³H]-PGI₂ is injected into healthy human males, 6.6% of the radioactivity is recovered from urine as [³H]-6-keto PGF_1α.

6-keto PGF_1α MaxSpec^® standard is a quantitative grade standard of 6-keto PGF_1α (Item No. 15210) that has been prepared specifically for mass spectrometry or any application where quantitative reproducibility is required. The solution has been prepared gravimetrically and is supplied in a deactivated glass ampule sealed under argon. The concentration was verified by comparison to an independently prepared calibration standard. This 6-keto PGF_1α MaxSpec^® standard is guaranteed to meet identity, purity, stability, and concentration specifications and is provided with a batch-specific certificate of analysis. Ongoing stability testing is performed to ensure the concentration remains accurate throughout the shelf life of the product. Note: The amount of solution added to the vial is in excess of the listed amount. Therefore, it is necessary to accurately measure volumes for preparation of calibration standards. Follow recommended storage and handling conditions to maintain product quality.

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製品詳細

name	6-keto Prostaglandin F1α MaxSpec Standard
Formal Name	6-oxo-9α,11α,15S-trihydroxy-prost-13E-en-1-oic acid
CAS Number	58962-34-8
Synonyms	6-keto PGF1α
Molecular Formula	C20H34O6
Formula Weight	370.5
Purity	≥95%
Formulation	A solution in methyl acetate
SMILES	CCCCCC(O)CC[C@H]1C(O)CC(O)C1CC(=O)CCCCC(=O)O
Storage	-20°C
Shipping	Wet ice in continental US; may vary elsewhere
Stability	≥ 1 year

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文献

1. Pace-Asciak, C.R. Isolation, structure, and biosynthesis of 6-ketoprostaglandin F1α in the rat stomach. J. Am. Chem. Soc. 98(8), 2348-2349 (1976).

2. Johnson, R.A., Morton, D.R., Kinner, J.H., et al. The chemical structure of prostaglandin X (prostacyclin). Prostaglandins 12(6), 915-928 (1976).

3. Brash, A.R., Jackson, E.K., Saggese, C.A., et al. Metabolic disposition of prostacyclin in humans. J. Pharmacol. Exp. Ther. 226(1), 78-87 (1983).

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