抗MOG [C2C3], C-term抗体 | Anti-MOG [C2C3], C-term antibody

• 特長
• 価格
• DATA IMAGES
• 製品情報
• APPLICATION
• PROPERTIES
• TARGET
• REFERENCEE(抜粋)

特長

• 高品質の抗体です。
• 幅広い研究分野に関連する抗体を取り揃えています。
• 使用されたアプリケーションや動物種などの情報が充実しています。
• 多数の論文で使用実績がある信頼性の高い抗体です。

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価格

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DATA IMAGES

	MOG antibody [C2C3], C-term detects MOG protein by immunofluorescent analysis.Sample: DIV9 rat E18 primary cortical neurons and glia cells were fixed in 4% paraformaldehyde at RT for 15 min.Green: MOG protein stained by MOG antibody [C2C3], C-term (GTX106283) diluted at 1:500.Red: beta Tubulin 3/ Tuj1, stained by beta Tubulin 3/ Tuj1 antibody [GT886] (GTX631830) diluted at 1:500.Blue: Fluoroshield with DAPI (GTX30920).
	Various tissue extracts (50 μg) were separated by 12% SDS-PAGE, and the membrane was blotted with MOG antibody [C2C3], C-term (GTX106283) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
	MOG antibody [C2C3], C-term detects MOG protein expression by immunohistochemical analysis.Sample: Frozen-sectioned adult mouse cerebellum. Green: MOG protein stained by MOG antibody [C2C3], C-term (GTX106283) diluted at 1:250.Red: NeuN, stained by NeuN antibody [2Q158] (GTX30773) diluted at 1:500.Blue: Fluoroshield with DAPI (GTX30920).

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製品情報

Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Application	WB, ICC/IF, IHC-Fr
Reactivity	Mouse, Rat

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APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Dilution
WB	1:500-1:3000
ICC/IF	1:100-1:1000
IHC-Fr	1:100-1:1000

Not tested in other applications.

Calculated MW	28 kDa. ( Note )
Positive Control	mouse brain , rat brain
Predict Reactivity	Human(>80% identity)

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PROPERTIES

Form	Liquid
Buffer	1XPBS, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Storage	Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration	1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species	Human
Immunogen	Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human MOG. The exact sequence is proprietary.
Purification	Purified by antigen-affinity chromatography.
Conjugation	Unconjugated
Note	For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

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TARGET

Synonyms	myelin oligodendrocyte glycoprotein , BTN6 , BTNL11 , MOGIG2 , NRCLP7
Cellular Localization	Isoform 1: Cell membrane; Multi-pass membrane protein , Isoform 5: Cell membrane; Multi-pass membrane protein , Isoform 2: Cell membrane; Single-pass type I membrane protein , Isoform 3: Cell membrane; Single-pass type I membrane protein , Isoform 4: Cell
Background	The product of this gene is a membrane protein expressed on the oligodendrocyte cell surface and the outermost surface of myelin sheaths. Due to this localization, it is a primary target antigen involved in immune-mediated demyelination. This protein may be involved in completion and maintenance of the myelin sheath and in cell-cell communication. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq]
Database	・ Gene ID: 4340 MOG ・ UniProt: Q16653 MOG

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REFERENCEE(抜粋)

Application Reference	Application/Reactivity
Inamura N et al. Neurobiol Dis. 2018; 120 : 51-62 Developmental defects and aberrant accumulation of endogenous psychosine in oligodendrocytes in a murine model of Krabbe disease.	Application : WB Reactivity : Mouse

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