抗BMP-4抗体(Anti-BMP-4, Human, Mouse-Mono, Biotin antibody)

• 価格
• Product Details
• Applications and Data
• Related Research Areas
• Related Product & Information

価格

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Product Details

Species Reactivity	Human, Primate
Label	Biotin
Immunogen	Mouse myeloma cell line NS0-derived recombinant human BMP‑4Ser293-Arg408Accession # P12644
Source	Monoclonal Mouse IgG1 Clone # 66108
Purification	Protein A or G purified from hybridoma culture supernatant
Specificity	Detects human and primate BMP-4 in direct ELISAs and Western blots. Does not cross-react with recombinant human BMP‑2, ‑3, ‑5, ‑6, or ‑7.

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Applications and Data

	Recommended Concentration	Sample
Western Blot	1 µg/mL	Recombinant Human BMP‑4 (Catalog # 314-BP)
Human/Primate BMP-4 Sandwich Immunoassay	Reagent
ELISA Capture (Matched Antibody Pair)	2-8 µg/mL	Human/Primate BMP‑4 Antibody (Catalog #MAB7571 )
ELISA Detection (Matched Antibody Pair)	0.5-2.0 µg/mL	Human/Primate BMP‑4 Biotinylated Antibody (Catalog #BAM7572 )
ELISA Standard		Recombinant Human BMP-4 Protein (Catalog #314-BP )
Please Note: Optimal dilutions should be determined by each laboratory for each application.General Protocolsare available in the Technical Information section on our website.		Preparation and Storage
Reconstitution	Reconstitute at 0.5 mg/mL in sterile PBS.	Reconstitution Buffer Available
Shipping	The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: BMP-4	BMP-4 is one of at least 20 structurally and functionally related BMPswhich are members of the TGF-beta  superfamily. Biologically active BMP-4is a disulfide-linked homodimer of the carboxy-terminal domain. Themorphogenetic effects of BMP-4 on various tissues are mediated by typeI and type II BMP receptors.
Long Name:	Bone Morphogenetic Protein 4
Entrez Gene IDs:	652 (Human); 12159 (Mouse); 25296 (Rat); 30612 (Zebrafish)
Alternate Names:	BMP-2B; BMP2B1; BMP2BMCOPS6; BMP4; BMP-4; Bone morphogenetic protein 2B; bone morphogenetic protein 4; DVR4; OFC11; ZYME

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Related Research Areas

BMP Family

BMPs (Bone Morphogenetic Proteins)

BMPs and Regulators Secreted by Endothelial Cells

Cardiac Stem Cell Markers

Early Ectodermal Lineage Markers

Early Mesodermal Lineage Markers

EMT Induction

Molecules Secreted by VSMC

Neural Crest Cell Markers

TGF-beta Superfamily

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Related Product & Information

Background	BMP-4
background_content	Background: BMP-4 BMP-4 is one of at least 20 structurally and functionally related BMPs which are members of the TGF-beta  superfamily. Biologically active BMP-4 is a disulfide-linked homodimer of the carboxy-terminal domain. The morphogenetic effects of BMP-4 on various tissues are mediated by type I and type II BMP receptors.

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