抗Flt-1抗体(Anti-Flt-1, Human, Mouse-Mono, PE antibody)

• 価格
• Product Details
• Applications and Data
• Related Product & Information
• Citations

価格

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Product Details

Species Reactivity	Human
Label	Phycoerythrin
Immunogen	S. frugiperda insect ovarian cell line Sf 21-derived recombinant human VEGF R1/Flt-1Ser27-His687Accession # NP_001153392
Source	Monoclonal Mouse IgG1 Clone # 49560
Purification	Protein A or G purified from hybridoma culture supernatant
Specificity	Detects human VEGF R1/Flt-1 in direct ELISAs and Western blots. In Western blots, this antibody does not cross-react with recombinant mouse VEGF R1, recombinant human (rh) VEGF R2, rhVEGF R3, or rhVEGF R4.

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Applications and Data

	Recommended Concentration	Sample
Flow Cytometry	10 µL/106 cells	See below

Flow Cytometry
	Detection of VEGF R1/Flt‑1 in HUVEC Human Cells by Flow Cytometry. HUVEC human umbilical vein endothelial cells were stained with Mouse Anti-Human VEGF R1/Flt‑1 PE‑conjugated Monoclonal Antibody (Catalog # FAB321P, filled histogram) or isotype control antibody (Catalog # IC002P, open histogram). View our protocol for Staining Membrane-associated Proteins.

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Related Product & Information

Long Name	Vascular Endothelial Growth Factor Receptor 1
Background	VEGF R1/Flt-1
background_content	Background: VEGF R1/Flt-1 Vascular Endothelial Growth Factor Receptor 1 (VEGF R1) is a receptor tyrosine kinase that is expressed primarily on endothelial cells and plays a role in vasculogenesis and angiogenesis. A soluble variant of VEGF R1 was also reported to bind VEGF and PlGF with high affinity and function as a potent VEGF antagonist.

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Citations

1. A quantitative method for screening and identifying molecular targets for nanomedicine
   Authors: P Guo, J Yang, DR Bielenberg, D Dillon, D Zurakowski, MA Moses, DT Auguste
   J Control Release, 2017;0(0):.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


2. The distribution and potential prognostic value of SMAD protein expression in chronic lymphocytic leukemia
   Authors: M Witkowska, A Majchrzak, B Cebula-Obr, E Wawrzyniak, T Robak, P Smolewski
   Tumour Biol, 2017;39(3):1010428317694.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


3. BRAF Inhibition Stimulates Melanoma-Associated Macrophages to Drive Tumor Growth.
   Authors: Wang T, Xiao M, Ge Y, Krepler C, Belser E, Lopez-Coral A, Xu X, Zhang G, Azuma R, Liu Q, Liu R, Li L, Amaravadi R, Xu W, Karakousis G, Gangadhar T, Schuchter L, Lieu M, Khare S, Halloran M, Herlyn M, Kaufman R
   Clin Cancer Res, 2015;21(7):1652-64.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


4. Metabolic impact of anti-angiogenic agents on U87 glioma cells.
   Authors: Mesti T, Savarin P, Triba M, Le Moyec L, Ocvirk J, Banissi C, Carpentier A
   PLoS ONE, 2014;9(6):e99198.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


5. Interaction of mesenchymal stem cells with fibroblast-like synoviocytes via cadherin-11 promotes angiogenesis by enhanced secretion of placental growth factor.
   Authors: Park, Su-Jung, Kim, Ki-Jo, Kim, Wan-Uk, Cho, Chul-Soo
   J Immunol, 2014;192(7):3003-10.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


6. Antiangiogenic cancer drug sunitinib exhibits unexpected proangiogenic effects on endothelial cells.
   Authors: Norton, Kerri-An, Han, Zheyi, Popel, Aleksand, Pandey, Niranjan
   Onco Targets Ther, 2014;7(0):1571-82.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


7. Laminin promotes vascular network formation in 3D in vitro collagen scaffolds by regulating VEGF uptake.
   Authors: Stamati K, Priestley J, Mudera V, Cheema U
   Exp Cell Res, 2014;327(1):68-77.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


8. Differential sensitivity of prostate tumor derived endothelial cells to sorafenib and sunitinib.
   Authors: Fiorio Pla, Alessand, Brossa, Alessia, Bernardini, Michela, Genova, Tullio, Grolez, Guillaum, Villers, Arnaud, Leroy, Xavier, Prevarskaya, Natalia, Gkika, Dimitra, Bussolati, Benedett
   BMC Cancer, 2014;14(0):939.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


9. Immunophenotypic characterization of human monocyte subsets: possible implications for cardiovascular disease pathophysiology.
   Authors: Shantsila E, Wrigley B, Tapp L, Apostolakis S, Montoro-Garcia S, Drayson MT, Lip GY
   J. Thromb. Haemost., 2011;9(5):1056-66.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


10. VEGFR2 is selectively expressed by FOXP3high CD4+ Treg.
    Authors: Suzuki H, Onishi H, Wada J, Yamasaki A, Tanaka H, Nakano K, Morisaki T, Katano M
    Eur. J. Immunol., 2010;40(1):197-203.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow

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