抗Mouse CXCR4 Phycoerythrin抗体(Anti-Mouse CXCR4 Phycoerythrin antibody)

• 価格
• Product Details
• Applications and Data
• Related Product & Information
• Citations

価格

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Product Details

Species Reactivity	Mouse
Label	Phycoerythrin
Immunogen	Y3 rat myeloid cell line transfected with mouse CXCR4Met1-Ser359Accession # P70658
Source	Monoclonal Rat IgG2B Clone # 247506
Purification	Protein A or G purified from hybridoma culture supernatant
Specificity	Detects mouse CXCR4 transfectants. Does not stain irrelevant transfectants.

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Applications and Data

	Recommended Concentration	Sample
Flow Cytometry	10 µL/106 cells	See below

Flow Cytometry
	Detection of CXCR4 in Mouse Thymocytes by Flow Cytometry. Mouse thymocytes were stained with (A) Rat Anti-Mouse CXCR4 PE‑conjugated Monoclonal Antibody (Catalog # FAB21651P) or (B) Rat IgG2B isotype control antibody (Catalog # IC013P) and Rat anti-Mouse CD8 alpha APC-conjugated Monoclonal Antibody (Catalog # FAB116A). View our protocol for Staining Membrane-associated Proteins.

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Related Product & Information

Entrez Gene IDs	7852 (Human); 12767 (Mouse); 60628 (Rat); 483900 (Canine); 493676 (Feline)
Background	CXCR4
background_content	Background: CXCR4 CXCR4 is a G-protein-linked seven transmembrane spanning receptor that binds stromal cell-derived factor-1 (SDF-1). CXCR4 acts as a co-factor for T-cell tropic HIV-1 and-2 viral entry into cells.

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Citations

1. Infection of Female BWF1 Lupus Mice with Malaria Parasite Attenuates B Cell Autoreactivity by Modulating the CXCL12/CXCR4 Axis and Its Downstream Signals PI3K/AKT, NFkappaB and ERK.
   Authors: Badr G, Sayed A, Abdel-Maksoud M, Mohamed A, El-Amir A, Abdel-Ghaffar F, Al-Quraishy S, Mahmoud M
   PLoS ONE, 2015;10(4):e0125340.
   Species: Mouse
   Sample Type: Whole Cells
   Application: Flow


2. Chemokine receptor CX3CR1 contributes to macrophage survival in tumor metastasis.
   Authors: Zheng, Jiao, Yang, Min, Shao, Jianghua, Miao, Yanju, Han, Jiahuai, Du, Jie
   Mol Cancer, 2013;12(1):141.
   Species: Mouse
   Sample Type: Whole Cells
   Application: Flow


3. G protein-coupled receptor kinase-3-deficient mice exhibit WHIM syndrome features and attenuated inflammatory responses.
   Authors: Tarrant, Teresa K, Billard, Matthew, Timoshchenko, Roman G, McGinnis, Marcus W, Serafin, D Stephe, Foreman, Oded, Esserman, Denise A, Chao, Nelson J, Lento, William, Lee, David M, Patel, Dhavalku, Siderovski, David P
   J Leukoc Biol, 2013;94(6):1243-51.
   Species: Mouse
   Sample Type: Whole Cells
   Application: Flow


4. MicroRNA126 contributes to granulocyte colony-stimulating factor-induced hematopoietic progenitor cell mobilization by reducing the expression of vascular cell adhesion molecule 1.
   Authors: Salvucci O, Jiang K, Gasperini P
   Haematologica, 2012;97(6):818-26.
   Species: Mouse
   Sample Type: Whole Cells
   Application: Flow


5. CXCL12 enhances exogenous CD4+CD25+ T cell migration and prevents embryo loss in non-obese diabetic mice.
   Authors: Lin Y, Xu L, Jin H, Zhong Y, Di J, Lin QD
   Fertil. Steril., 2009;91(6):2687-96.
   Species: Mouse
   Sample Type: Whole Cells
   Application: Flow


6. The angiogenic response is dictated by beta3 integrin on bone marrow-derived cells.
   Authors: Feng W, McCabe NP, Mahabeleshwar GH, Somanath PR, Phillips DR, Byzova TV
   J. Cell Biol., 2008;183(6):1145-57.
   Species: Mouse
   Sample Type: Whole Cells
   Application: Flow

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