抗Human CCR10 Phycoerythrin抗体(Anti-Human CCR10 Phycoerythrin antibody)

• 価格
• Product Details
• Applications and Data
• Related Product & Information
• Citations

価格

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Product Details

Species Reactivity	Human
Label	Phycoerythrin
Immunogen	Y3 rat myeloid cell line transfected with human CCR10Gln8-Asn362Accession # P46092
Source	Monoclonal Rat IgG2A Clone # 314305
Purification	Protein A or G purified from hybridoma culture supernatant
Specificity	Detect human CCR10. Stains human CCR10-transfected cells but not irrelevant transfectants.

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Applications and Data

	Recommended Concentration	Sample
Flow Cytometry	10 µL/106 cells	See below

Flow Cytometry
	Detection of CCR10 in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human CD3 epsilon APC‑conjugated Monoclonal Antibody (Catalog # FAB100A) and either (A) Rat Anti-Human CCR10 PE‑conjugated Monoclonal Antibody (Catalog # FAB3478P) or (B) Rat IgG2A Phycoerythrin Isotype Control (Catalog # IC006P). View our protocol for Staining Membrane-associated Proteins.
Flow Cytometry
	Detection of CCR10 in L1.2 Mouse Cell Line Transfected with Human CCR10 and eGFP by Flow Cytometry. L1.2 mouse pro-B cell line transfected with human CCR10 and eGFP was stained with either (A) Rat Anti-Human CCR10 PE‑conjugated Monoclonal Antibody (Catalog # FAB3478P) or (B) Rat IgG2A Phycoerythrin Isotype Control (Catalog # IC006P). View our protocol for Staining Membrane-associated Proteins.

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Related Product & Information

Entrez Gene IDs	2826 (Human); 12777 (Mouse); 363682 (Rat)
Background	CCR10
background_content	Background: CCR10 CCR10 is a G protein-linked seven transmembrane domain protein expressed by T cells and B cell subsets that functions as a receptor for CCL27 and CCL28. CCR10 mediates lymphocyte migration to the skin and mucosa, and its expression is correlated with the metastatic behavior of melanomas.

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Citations

1. Skewing towards Treg and Th2 responses is a characteristic feature of sustained remission in ANCA-positive granulomatosis with polyangiitis
   Authors: W Szczeklik, B Jakie?a, K Wawrzycka-, M Sanak, M Hubalewska, A Padjas, M Surmiak, K Szczeklik, J Sznajd, J Musia?
   Eur. J. Immunol, 2017;0(0):.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


2. Functional Langerinhigh-Expressing Langerhans-like Cells Can Arise from CD14highCD16- Human Blood Monocytes in Serum-Free Condition
   Authors: G Picarda, C Chéneau, JM Humbert, G Bériou, P Pilet, J Martin, F Duteille, P Perrot, F Bellier-Wa, M Heslan, F Haspot, F Guillon, R Josien, FA Halary
   J Immunol, 2016;0(0):.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


3. Detection of Primary T Cell Responses to Drugs and Chemicals in HLA-Typed Volunteers: Implications for the Prediction of Drug Immunogenicity
   Authors: Lee Faulkner
   Toxicol. Sci, 2016;154(2):416-429.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


4. Glatiramer Acetate, Dimethyl Fumarate, and Monomethyl Fumarate Upregulate the Expression of CCR10 on the Surface of Natural Killer Cells and Enhance Their Chemotaxis and Cytotoxicity
   Authors: Zaidoon Al-Jaderi
   Front Immunol, 2016;7(0):437.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


5. The oral commensal Streptococcus mitis shows a mixed memory Th cell signature that is similar to and cross-reactive with Streptococcus pneumoniae.
   Authors: Engen S, Valen Rukke H, Becattini S, Jarrossay D, Blix I, Petersen F, Sallusto F, Schenck K
   PLoS ONE, 2014;9(8):e104306.
   Species: Human
   Sample Type: Whole Cells
   Application: IP


6. CXCR4/IgG-expressing plasma cells are associated with human gastrointestinal tissue inflammation.
   Authors: Buckner, Clarisa, Moir, Susan, Kardava, Lela, Ho, Jason, Santich, Brian H, Kim, Leo Jin, Funk, Emily K, Nelson, Amy K, Winckler, Britanny, Chairez, Cheryl L, Theobald-Whiting, Narda L, Anaya-O'Brien, Sandra, Alimchandani, Meghna, Quezado, Martha M, Yao, Michael, Kovacs, Joseph A, Chun, Tae-Wook, Fauci, Anthony, Malech, Harry L, De Ravin, Suk See
   J Allergy Clin Immunol, 2014;133(6):1676-85.e5.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


7. Intracellular coexpression of CXC- and CC- chemokine receptors and their ligands in human melanoma cell lines and dynamic variations after xenotransplantation.
   Authors: Pinto S, Martinez-Romero A, O'Connor J, Gil-Benso R, San-Miguel T, Terradez L, Monteagudo C, Callaghan R
   BMC Cancer, 2014;14(0):118.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


8. IL-7 licenses activation of human liver intrasinusoidal mucosal-associated invariant T cells.
   Authors: Tang, Xin-Zi, Jo, Juandy, Tan, Anthony, Sandalova, Elena, Chia, Adeline, Tan, Kai Chah, Lee, Kang Hoe, Gehring, Adam J, De Libero, Gennaro, Bertoletti, Antonio
   J Immunol, 2013;190(7):3142-52.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


9. Functionally distinct subsets of human FOXP3+ Treg cells that phenotypically mirror effector Th cells.
   Authors: Duhen T, Duhen R, Lanzavecchia A
   Blood, 2012;119(19):4430-40.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


10. Increased numbers of immature plasma cells in peripheral blood specifically overexpress chemokine receptor CXCR3 and CXCR4 in patients with ulcerative colitis.
    Authors: Hosomi S, Oshitani N, Kamata N, Sogawa M, Okazaki H, Tanigawa T, Yamagami H, Watanabe K, Tominaga K, Watanabe T, Fujiwara Y, Maeda K, Hirakawa K, Arakawa T
    Clin. Exp. Immunol., 2011;163(2):215-24.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow

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