抗Human CCR10 Allophycocyanin抗体(Anti-Human CCR10 Allophycocyanin antibody)

• 価格
• Product Details
• Applications and Data
• Related Product & Information
• Citations

価格

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Product Details

Species Reactivity	Human
Label	Allophycocyanin
Immunogen	Y3 rat myeloid cell line transfected with human CCR10Gln8-Asn362Accession # P46092
Source	Monoclonal Rat IgG2A Clone # 314305
Purification	Protein A or G purified from hybridoma culture supernatant
Specificity	Detect human CCR10. Stains human CCR10-transfected cells but not irrelevant transfectants.

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Applications and Data

	Recommended Concentration	Sample
Flow Cytometry	10 µL/106 cells	See below

Flow Cytometry
	Detection of CCR10 in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human CD3 epsilon Fluorescein‑conjugated Monoclonal Antibody (Catalog # FAB100F) and either (A) Rat Anti-Human CCR10 APC‑conjugated Monoclonal Antibody (Catalog # FAB3478A) or (B) Rat IgG2A Allophycocyanin Isotype Control (Catalog # IC006A). View our protocol for Staining Membrane-associated Proteins.
Flow Cytometry
	Detection of CCR10 in L1.2 Mouse Cell Line Transfected with Human CCR10 and eGFP by Flow Cytometry. L1.2 mouse pro-B cell line transfected with human CCR10 and eGFP was stained with either (A) Rat IgG2A Allophycocyanin Isotype Control (Catalog # IC006A) or (B) Rat Anti-Human CCR10 APC‑conjugated Monoclonal Antibody (Catalog # FAB3478A). View our protocol for Staining Membrane-associated Proteins.

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Related Product & Information

Entrez Gene IDs	2826 (Human); 12777 (Mouse); 363682 (Rat)
Background	CCR10
background_content	Background: CCR10 CCR10 is a G protein-linked seven transmembrane domain protein expressed by T cells and B cell subsets that functions as a receptor for CCL27 and CCL28. CCR10 mediates lymphocyte migration to the skin and mucosa, and its expression is correlated with the metastatic behavior of melanomas.

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Citations

1. A role for CCL28-CCR3 in T-cell homing to the human upper airway mucosa.
   Authors: Danilova, E, Skrindo, I, Gran, E, Hales, B J, Smith, W A, Jahnsen, J, Johansen, F E, Jahnsen, F L, Baekkevold, E S
   Mucosal Immunol, 2015;8(1):107-14.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


2. Plasmablasts as migratory IgG-producing cells in the pathogenesis of neuromyelitis optica.
   Authors: Chihara, Norio, Aranami, Toshimas, Oki, Shinji, Matsuoka, Takako, Nakamura, Masakazu, Kishida, Hitaru, Yokoyama, Kazumasa, Kuroiwa, Yoshiyuk, Hattori, Nobutaka, Okamoto, Tomoko, Murata, Miho, Toda, Tatsushi, Miyake, Sachiko, Yamamura, Takashi
   PLoS ONE, 2013;8(12):e83036.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


3. Steady-state generation of mucosal IgA+ plasmablasts is not abrogated by B-cell depletion therapy with rituximab.
   Authors: Mei HE, Frolich D, Giesecke C, Loddenkemper C, Reiter K, Schmidt S, Feist E, Daridon C, Tony HP, Radbruch A, Dorner T
   Blood, 2010;116(24):5181-90.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


4. CCL28 is increased in human Helicobacter pylori-induced gastritis and mediates recruitment of gastric immunoglobulin A-secreting cells.
   Authors: Hansson M, Hermansson M, Svensson H, Elfvin A, Hansson LE, Johnsson E, Sjoling A, Quiding-Jarbrink M
   Infect. Immun., 2008;76(7):3304-11.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow

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