抗NKG2C/CD159c抗体(Anti-Human NKG2C Allophycocyanin antibody)

• 価格
• Product Details
• Applications and Data
• Related Product & Information
• Citations

価格

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Product Details

Species Reactivity	Human
Label	Allophycocyanin
Immunogen	BaF3 mouse pro-B cell line transfected with human NKG2C/CD159c and CD94
Source	Monoclonal Mouse IgG1 Clone # 134591
Purification	Protein A or G purified from hybridoma culture supernatant
Specificity	Detects human NKG2C/CD159c heterodimer with CD94 in flow cytometry. It does not cross-react with the human NKG2A/CD94 heterodimer or with the human CD94 homodimer.

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Applications and Data

	Recommended Concentration	Sample
Flow Cytometry	10 µL/106 cells	See below

Flow Cytometry

Detection of NKG2C/CD159c in Human PBMC lymphocytes by Flow Cytometry. Human peripheral blood mononuclear cell (PBMC) lymphocytes were stained with Mouse Anti-Human NCAM‑1/CD56 PE‑conjugated Monoclonal Antibody (Catalog # FAB2408P) and either (A) Mouse Anti-Human NKG2C/CD159c APC‑conjugated Monoclonal Antibody (Catalog # FAB138A) or (B) Mouse IgG1 Allophycocyanin Isotype Control (Catalog # IC002A). View our protocol for Staining Membrane-associated Proteins.

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Related Product & Information

Long Name	Natural Killer G2C
Background	NKG2C/CD159c
background_content	Background: NKG2C/CD159c NKG2C, also known as hemoglobin scavenger receptor, is a type II transmembrane protein expressed exclusively in monocytes and macrophages. It is a scavenger receptor cysteine-rich superfamily (SRCR-SF) protein that contains nine SRCR motifs in its extracellular region.

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Citations

1. NK cells generate memory-type responses to human cytomegalovirus-infected fibroblasts
   Authors: N Newhook, N Fudge, M Grant
   Eur. J. Immunol., 2017;0(0):.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


2. NKG2C(+)CD57(+) Natural Killer Cell Expansion Parallels Cytomegalovirus-Specific CD8(+) T Cell Evolution towards Senescence
   Authors: John Heath
   J Immunol Res, 2016;2016(0):7470124.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


3. Impaired NK Cell Responses to Pertussis and H1N1 Influenza Vaccine Antigens in Human Cytomegalovirus-Infected Individuals.
   Authors: Nielsen C, White M, Bottomley C, Lusa C, Rodriguez-Galan A, Turner S, Goodier M, Riley E
   J Immunol, 2015;194(10):4657-67.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


4. Effector Vgamma9Vdelta2 T cells dominate the human fetal gammadelta T-cell repertoire.
   Authors: Dimova T, Brouwer M, Gosselin F, Tassignon J, Leo O, Donner C, Marchant A, Vermijlen D
   Proc Natl Acad Sci U S A, 2015;112(6):E556-65.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


5. Modulation of the natural killer cell KIR repertoire by cytomegalovirus infection.
   Authors: Charoudeh H, Terszowski G, Czaja K, Gonzalez A, Schmitter K, Stern M
   Eur J Immunol, 2013;43(2):480-7.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


6. Galectin-9 functionally impairs natural killer cells in humans and mice.
   Authors: Golden-Mason L, McMahan R, Strong M, Reisdorph R, Mahaffey S, Palmer B, Cheng L, Kulesza C, Hirashima M, Niki T, Rosen H
   J Virol, 2013;87(9):4835-45.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


7. Plasmodium falciparum-infected erythrocytes induce granzyme B by NK cells through expression of host-Hsp70.
   Authors: Bottger E, Multhoff G, Kun JF, Esen M
   PLoS ONE, 2012;7(3):e33774.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


8. Autologous antitumor activity by NK cells expanded from myeloma patients using GMP-compliant components.
   Authors: Alici E, Sutlu T, Bjorkstrand B, Gilljam M, Stellan B, Nahi H, Quezada HC, Gahrton G, Ljunggren HG, Dilber MS
   Blood, 2008;111(6):3155-62.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow

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