抗Mouse CXCR3 Allophycocyanin抗体(Anti-Mouse CXCR3 Allophycocyanin antibody)

• 価格
• Product Details
• Applications and Data
• Related Product & Information
• Citations

価格

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Product Details

Species Reactivity	Mouse
Label	Allophycocyanin
Immunogen	CHO Chinese hamster ovary cell line transfected with mouse CXCR3Met1-Leu367Accession # AAC40163
Source	Monoclonal Rat IgG2A Clone # 220803
Purification	Protein A or G purified from hybridoma culture supernatant
Specificity	Detects mouse CXCR3.

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Applications and Data

	Recommended Concentration	Sample
Flow Cytometry	10 µL/106 cells	See below

Flow Cytometry
	Detection of CXCR3 in Mouse Splenocytes by Flow Cytometry. Mouse splenocytes were stained with Rat Anti-Mouse CD3 PE‑conjugated Monoclonal Antibody (Catalog # FAB4841P) and either (A) Rat Anti-Mouse CXCR3 APC‑conjugated Monoclonal Antibody (Catalog # FAB1685A) or (B) Rat IgG2A Allophycocyanin Isotype Control (Catalog # IC006A). View our protocol for Staining Membrane-associated Proteins.

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Related Product & Information

Entrez Gene IDs	2833 (Human); 12766 (Mouse); 84475 (Rat)
Background	CXCR3
background_content	Background: CXCR3 CXCR3 is a G protein coupled chemokine receptor that binds the alpha chemokines MIG (CXCL9), IP-10 (CXCL10) and I-TAC (CXCL11). CXCR3 is expressed on activated T cells, B cells and NK cells.

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Citations

1. Cryptococcus gattii infection dampens Th1 and Th17 responses by attenuating dendritic cell function and pulmonary chemokine expression in the immunocompetent hosts.
   Authors: Angkasekwinai P, Sringkarin N, Supasorn O, Fungkrajai M, Wang Y, Chayakulkeeree M, Ngamskulrungroj P, Angkasekwinai N, Pattanapanyasat K
   Infect Immun, 2014;82(9):3880-90.
   Species: Mouse
   Sample Type: Whole Cells
   Application: Flow


2. The developmental pathway for CD103(+)CD8+ tissue-resident memory T cells of skin.
   Authors: Mackay L, Rahimpour A, Ma J, Collins N, Stock A, Hafon M, Vega-Ramos J, Lauzurica P, Mueller S, Stefanovic T, Tscharke D, Heath W, Inouye M, Carbone F, Gebhardt T
   Nat Immunol, 2013;14(12):1294-301.
   Species: Mouse
   Sample Type: Whole Cells
   Application: Flow


3. CXCL9 causes heterologous desensitization of CXCL12-mediated memory T lymphocyte activation.
   Authors: Giegold O, Ogrissek N, Richter C, Schroder M, Herrero San Juan M, Pfeilschifter J, Radeke H
   J Immunol, 2013;190(7):3696-705.
   Species: Mouse
   Sample Type: Whole Cells
   Application: Flow


4. Early differentiated CD138(high) MHCII+ IgG+ plasma cells express CXCR3 and localize into inflamed kidneys of lupus mice.
   Authors: Lacotte S, Decossas M, Le Coz C, Brun S, Muller S, Dumortier H
   PLoS ONE, 2013;8(3):e58140.
   Species: Mouse
   Sample Type: Whole Cells
   Application: Flow


5. Chemokine receptor CXCR3 promotes growth of glioma.
   Authors: Liu C, Luo D, Reynolds BA
   Carcinogenesis, 2011;32(2):129-37.
   Species: Mouse
   Sample Type: Whole Cells
   Application: Flow


6. Chemokine gene expression during fatal murine cerebral malaria and protection due to CXCR3 deficiency.
   Authors: Miu J, Mitchell AJ, Muller M, Carter SL, Manders PM, McQuillan JA, Saunders BM, Ball HJ, Lu B, Campbell IL, Hunt NH
   J. Immunol., 2008;180(2):1217-30.
   Species: Mouse
   Sample Type: Whole Cells
   Application: Flow

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