抗Human CXCR4 Phycoerythrin抗体(Anti-Human CXCR4 Phycoerythrin antibody)

• 価格
• Product Details
• Applications and Data
• Related Product & Information
• Citations

価格

目次に戻る

Product Details

Species Reactivity	Human
Label	Phycoerythrin
Immunogen	CP-MAC-infected SUP-T1 human T cell lymphoblastic lymphoma lineAccession # P61073
Source	Monoclonal Mouse IgG2A Clone # 12G5
Purification	Protein A or G purified from ascites
Specificity	Detects human CXCR4.

目次に戻る

Applications and Data

	Recommended Concentration	Sample
Flow Cytometry	10 µL/106 cells	See below

Flow Cytometry
	Detection of CXCR4 in Human Blood Lymphocytes by Flow Cytometry. Human peripheral blood lymphocytes were stained with Mouse Anti-Human CXCR4 PE‑conjugated Monoclonal Antibody (Catalog # FAB170P) and Mouse Anti-Human CD19 APC‑conjugated Monoclonal Antibody (Catalog # FAB4867A). View our protocol for Staining Membrane-associated Proteins.

目次に戻る

Related Product & Information

Background	CXCR4
background_content	Background: CXCR4 CXCR4 is a G-protein-linked seven transmembrane spanning receptor that binds stromal cell-derived factor-1 (SDF-1). CXCR4 acts as a co-factor for T-cell tropic HIV-1 and -2 viral entry into cells.

目次に戻る

Citations

1. Epithelial-to-mesenchymal transition in FHC-silenced cells: the role of CXCR4/CXCL12 axis
   Authors: I Aversa, F Zolea, C Ieranò, S Bulotta, AM Trotta, MC Faniello, C De Marco, D Malanga, F Biamonte, G Viglietto, G Cuda, S Scala, F Costanzo
   J. Exp. Clin. Cancer Res., 2017;36(1):104.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


2. Extensive Characterization and Comparison of Endothelial Cells Derived from Dermis and Adipose Tissue: Potential Use in Tissue Engineering
   PLoS ONE, 2016;11(11):e0167056.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


3. Mesenchymal stromal cell secretome up-regulates 47 kDa CXCR4 expression, and induce invasiveness in neuroblastoma cell lines.
   Authors: Shankar V, Hori H, Kihira K, Lei Q, Toyoda H, Iwamoto S, Komada Y
   PLoS ONE, 2015;10(3):e0120069.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


4. IL-24 inhibits lung cancer cell migration and invasion by disrupting the SDF-1/CXCR4 signaling axis.
   Authors: Panneerselvam J, Jin J, Shanker M, Lauderdale J, Bates J, Wang Q, Zhao Y, Archibald S, Hubin T, Ramesh R
   PLoS ONE, 2015;10(3):e0122439.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


5. PI3K/mTORC2 regulates TGF-beta/Activin signalling by modulating Smad2/3 activity via linker phosphorylation.
   Authors: Yu J, Ramasamy T, Murphy N, Holt M, Czapiewski R, Wei S, Cui W
   Nat Commun, 2015;6(0):7212.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


6. The high-affinity CXCR4 antagonist BKT140 is safe and induces a robust mobilization of human CD34+ cells in patients with multiple myeloma.
   Authors: Peled A, Abraham M, Avivi I, Rowe J, Beider K, Wald H, Tiomkin L, Ribakovsky L, Riback Y, Ramati Y, Aviel S, Galun E, Shaw H, Eizenberg O, Hardan I, Shimoni A, Nagler A
   Clin Cancer Res, 2014;20(2):469-79.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


7. Conversion of peripheral blood NK cells to a decidual NK-like phenotype by a cocktail of defined factors.
   Authors: Cerdeira A, Rajakumar A, Royle C, Lo A, Husain Z, Thadhani R, Sukhatme V, Karumanchi S, Kopcow H
   J Immunol, 2013;190(8):3939-48.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


8. CXCR4 positive and angiogenic monocytes in myocardial infarction.
   Thromb Haemost, 2013;109(2):255-62.
   Species: Human
   Sample Type: Whole Blood
   Application: Flow


9. KDR identifies a conserved human and murine hepatic progenitor and instructs early liver development.
   Authors: Goldman O, Han S, Sourisseau M, Dziedzic N, Hamou W, Corneo B, D'Souza S, Sato T, Kotton D, Bissig K, Kalir T, Jacobs A, Evans T, Evans M, Gouon-Evans V
   Cell Stem Cell, 2013;12(6):748-60.
   


10. A novel chemically directed route for the generation of definitive endoderm from human embryonic stem cells based on inhibition of GSK-3.
    Authors: Bone HK, Nelson AS, Goldring CE, Tosh D, Welham MJ
    J. Cell. Sci., 2011;124(0):1992-2000.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow

目次に戻る