抗VEGF抗体(Anti-VEGF, Mouse-Mono antibody)
掲載日情報:2019/10/21 現在Webページ番号:29266
VEGFに対する抗体(Anti-VEGF, Mouse-Mono )です。
※ 本製品は研究用です。研究用以外には使用できません。
追加しました。
価格
[在庫・価格 :2025年04月26日 20時55分現在]
詳細 | 商品名 |
|
文献数 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Anti-VEGF, Mouse-Mono(211615) |
|
2 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Anti-Zebrafish VEGF MAb (Clone 211615) |
|
0 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|
[在庫・価格 :2025年04月26日 20時55分現在]
Anti-VEGF, Mouse-Mono(211615)
文献数: 2
- 商品コード:MAB1247
- メーカー:RSD
- 包装:500μg
- 価格:¥121,000
- 在庫:無(未発注)
- 納期:10日程度 ※※ 表示されている納期は弊社に在庫がなく、取り寄せた場合の目安納期となります。
- 法規制等:
説明文 | 別名:MVCD1 クローン:211615 Genbank No: 7422 Protein Accession No: O73682.1 |
||||||
---|---|---|---|---|---|---|---|
別包装品 | 別包装品あり | ||||||
法規制等 | |||||||
保存条件 | -20℃ | 法規備考 | |||||
抗原種 | Zebrafish | 免疫動物 | Mouse | ||||
交差性 | Zebrafish | 適用 | Neutralising,Western Blot | ||||
標識 | Unlabeled | 性状 | Protein A/G Affinity Purified | ||||
吸収処理 | クラス | IgG | |||||
クロナリティ | Monoclonal | フォーマット | |||||
掲載カタログ |
|
||||||
製品記事 | M1/M2 Macrophage Activation Marker Myeloid-derived Suppressor Cell Marker |
||||||
関連記事 |
Anti-Zebrafish VEGF MAb (Clone 211615)
文献数: 0
- 商品コード:MAB1247-SP
- メーカー:RSD
- 包装:25μg
- 価格:¥30,000
- 在庫:無(未発注)
- 納期:2~3週間 ※※ 表示されている納期は弊社に在庫がなく、取り寄せた場合の目安納期となります。
- 法規制等:
説明文 | ※受注発注品。形状:溶液または凍結乾燥 別名:MVCD1 クローン:211615 Genbank No: 7422 Protein Accession No: O73682.1 |
||||||
---|---|---|---|---|---|---|---|
別包装品 | 別包装品あり | ||||||
法規制等 | |||||||
保存条件 | 法規備考 | ||||||
抗原種 | 免疫動物 | Mouse | |||||
交差性 | Zebrafish | 適用 | Neutralising,Western Blot | ||||
標識 | Unlabeled | 性状 | Protein A/G Affinity Purified | ||||
吸収処理 | クラス | IgG | |||||
クロナリティ | Monoclonal | フォーマット | |||||
掲載カタログ |
|
||||||
製品記事 | M1/M2 Macrophage Activation Marker 使いっきり抗体 Myeloid-derived Suppressor Cell Marker |
||||||
関連記事 |
追加しました。
Product Details
Species Reactivity | Zebrafish |
---|---|
Label | Unconjugated |
Immunogen | S. frugiperda insect ovarian cell line Sf 21-derived recombinant zebrafish VEGF165Ala24-Arg188Accession # O73682.1 |
Source | Monoclonal Mouse IgG2B Clone # 211615 |
Purification | Protein A or G purified from hybridoma culture supernatant |
Specificity | Detects zebrafish VEGF in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross‑reactivity with recombinant human (rh) VEGF121, 165, 206, rhVEGF-B186, rhVEGF-C, rhVEGF‑D, recombinant mouse (rm) VEGF115, rmVEGF165, rmVEGF-B186, rmVEGF‑D, or recombinant rat VEGF164 is observed. |
追加しました。
Applications and Data
Recommended Concentration | Sample | |
Western Blot | 1 µg/mL | Recombinant Zebrafish VEGF165 (Catalog # 1247-ZV) |
Neutralization | Measured by its ability to neutralize VEGF165-induced proliferation in HUVEC human umbilical vein endothelial cells. The Neutralization Dose (ND50) is typically 0.2-0.5 µg/mL in the presence of 100 ng/mL Recombinant Zebraship VEGF165. |
追加しました。
Related Product & Information
Long Name | Vascular Endothelial Growth Factor |
---|---|
Entrez Gene IDs | 7422 (Human); 22339 (Mouse); 83785 (Rat); 281572 (Bovine); 403802 (Canine); 493845 (Feline); 30682 (Zebrafish) |
Background | VEGF |
background_content | Background: VEGF Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF) and VEGF-A, is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the PDGF family that is characterized by the presence of eight conserved cysteine residues. In human, at least eight alternate splice isoforms of VEGF-A, ranging from 206 amino acids (aa) to 121 aa in length, are known. In zebrafish, two VEGF isoforms, a 165 aa and a 121 aa isoform, have been reported. Mature zebrafish VEGF165 shares 64%, 62% and 62% aa sequence identity with frog, human, and mouse VEGF165, respectively. There are two tyrosine kinase receptors for VEGF reported in mammals termed VEGF R1 and VEGF R2/FLK-1. One receptor has been identified in zebrafish (FLK-1), and this may actually represent the orthologue to the early common ancestor for mammalian VEGF R1 and R2. All receptors are type I transmembrane proteins that show seven immunoglobulin-like domains extracellularly and a split kinase domain intracellularly. In addition to the tyrosine kinase receptors, neuropilin-1 (NRP-1) has been reported to be a coreceptor for VEGF binding. It is proposed that the presence of NRP-1 lowers the concentration of VEGF necessary for activation of VEGF R2. NRP-1 has been reported in both zebrafish and human. VEGF regulates multiple biological functions in endothelial cells, including cell proliferation, migration and survival. These functions of VEGF are mediated partly through the induction of nitric oxide and prostacyclin, as well as upregulation of metalloproteinases. Together with other vascular-specific growth factors such as the Angiopoietins, VEGF have separate but complementary roles in angiogenesis and vasculogenesis (1‑7). |
追加しました。
Citations
- CUL2 is required for the activity of hypoxia-inducible factor and vasculogenesis.
Authors: Maeda Y, Suzuki T, Pan X, Chen G, Pan S, Bartman T, Whitsett JA
J. Biol. Chem., 2008;283(23):16084-92.
Species: Zebrafish
Sample Type: Tissue Homogenates
Application: WB - Microarray gene expression profiling of cell lines from primary and metastatic tongue squamous cell carcinoma: possible insights from emerging technology.
Authors: Vigneswaran N, Sacks P, Gilcrease M, Zacharias W
J. Oral Pathol. Med., 2005;34(2):77-86.
Species: Human
Sample Type: Whole Cells
Application: ICC
追加しました。
製品情報は掲載時点のものですが、価格表内の価格については随時最新のものに更新されます。お問い合わせいただくタイミングにより製品情報・価格などは変更されている場合があります。
表示価格に、消費税等は含まれていません。一部価格が予告なく変更される場合がありますので、あらかじめご了承下さい。