抗Human CXCR3 Phycoerythrin抗体(Anti-Human CXCR3 Phycoerythrin antibody)

• 価格
• Product Details
• Applications and Data
• Related Product & Information
• Citations

価格

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Product Details

Species Reactivity	Human
Label	Phycoerythrin
Immunogen	NS0 mouse myeloma cell line transfected with human CXCR3Met1-Leu368Accession # P49682
Source	Monoclonal Mouse IgG1 Clone # 49801
Purification	Protein A or G purified from ascites
Specificity	Detects human CXCR3.

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Applications and Data

	Recommended Concentration	Sample
Flow Cytometry	10 µL/106 cells	See below

Flow Cytometry

Detection of CXCR3 in Human Blood Lymphocytes by Flow Cytometry. Human peripheral blood lymphocytes were stained with Mouse Anti-Human CXCR3 PE‑conjugated Monoclonal Antibody (Catalog # FAB160P) and Mouse Anti-Human CD3 epsilon Alexa Fluor® 700‑conjugated Monoclonal Antibody (Catalog # FAB100N). Quadrant markers were set based on control antibody staining (Catalog # IC002P). View our protocol for Staining Membrane-associated Proteins.

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Related Product & Information

Entrez Gene IDs	2833 (Human); 12766 (Mouse); 84475 (Rat)
Background	CXCR3
background_content	Background: CXCR3 CXCR3 is a G protein-coupled chemokine receptor that binds the alpha chemokines MIG (CXCL9), IP-10 (CXCL10), and I-TAC (CXCL11). CXCR3 is expressed on activated T cells, B cells, and NK cells.

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Citations

1. Autosomal dominant gain of function STAT1 mutation and severe bronchiectasis
   Authors: O Breuer, H Daum, M Cohen-Cymb, S Unger, D Shoseyov, P Stepensky, B Keller, K Warnatz, E Kerem
   Respir Med, 2017;126(0):39-45.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


2. IL-27 in human secondary lymphoid organs attracts myeloid dendritic cells and impairs HLA class I-restricted antigen presentation.
   Authors: Morandi, Fabio, Di Carlo, Emma, Ferrone, Soldano, Petretto, Andrea, Pistoia, Vito, Airoldi, Irma
   J Immunol, 2014;192(6):2634-42.
   


3. IL-12 directs further maturation of ex vivo differentiated NK cells with improved therapeutic potential.
   Authors: Lehmann, Dorit, Spanholtz, Jan, Sturtzel, Caterina, Tordoir, Marleen, Schlechta, Bernhard, Groenewegen, Dirk, Hofer, Erhard
   PLoS ONE, 2014;9(1):e87131.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


4. Human trophectoderm apposition is regulated by interferon gamma-induced protein 10 (IP-10) during early implantation.
   Authors: Sela H, Goldman-Wohl D, Haimov-Kochman R, Greenfield C, Natanson-Yaron S, Hamani Y, Revel A, Lavy Y, Singer O, Yachimovich-Cohen N, Turetsky T, Mandelboim O, Reubinoff B, Yagel S
   Placenta, 2013;34(3):222-30.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


5. Expression and functional heterogeneity of chemokine receptors CXCR4 and CXCR7 in primary patient-derived glioblastoma cells.
   Authors: Liu, Che, Pham, Kien, Luo, Defang, Reynolds, Brent A, Hothi, Parvinde, Foltz, Gregory, Harrison, Jeffrey
   PLoS ONE, 2013;8(3):e59750.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


6. Conversion of peripheral blood NK cells to a decidual NK-like phenotype by a cocktail of defined factors.
   Authors: Cerdeira A, Rajakumar A, Royle C, Lo A, Husain Z, Thadhani R, Sukhatme V, Karumanchi S, Kopcow H
   J Immunol, 2013;190(8):3939-48.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


7. Increased numbers of immature plasma cells in peripheral blood specifically overexpress chemokine receptor CXCR3 and CXCR4 in patients with ulcerative colitis.
   Authors: Hosomi S, Oshitani N, Kamata N, Sogawa M, Okazaki H, Tanigawa T, Yamagami H, Watanabe K, Tominaga K, Watanabe T, Fujiwara Y, Maeda K, Hirakawa K, Arakawa T
   Clin. Exp. Immunol., 2011;163(2):215-24.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


8. Thymoquinone inhibits the CXCL12-induced chemotaxis of multiple myeloma cells and increases their susceptibility to Fas-mediated apoptosis.
   Authors: Badr G, Lefevre EA, Mohany M
   PLoS ONE, 2011;6(9):e23741.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


9. Distinct roles for CCR4 and CXCR3 in the recruitment and positioning of regulatory T cells in the inflamed human liver.
   Authors: Oo YH, Weston CJ, Lalor PF, Curbishley SM, Withers DR, Reynolds GM, Shetty S, Harki J, Shaw JC, Eksteen B, Hubscher SG, Walker LS, Adams DH
   J. Immunol., 2010;184(6):2886-98.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


10. CD56highCD16-CD62L- NK cells accumulate in allergic contact dermatitis and contribute to the expression of allergic responses.
    Authors: Carbone T, Nasorri F, Pennino D
    J. Immunol., 2010;184(2):1102-10.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow

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