抗Human TNF RII/TNFRSF1B抗体(Anti-Human TNF RII/TNFRSF1B antibody)
掲載日情報:2021/01/28 現在Webページ番号:28561
Human TNF RII/TNFRSF1Bに対する抗体(Anti-Human TNF RII/TNFRSF1B )です。
※ 本製品は研究用です。研究用以外には使用できません。
追加しました。
- 価格
- Product Details
- Applications and Data
- Data Examples
- Related Research Areas
- Summary
- Summary
- Related Product & Information
- Citations
価格
[在庫・価格 :2026年04月06日 20時55分現在]
| 詳細 | 商品名 |
|
文献数 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
Anti-Human TNF RII/TNFRSF1B MAb (Clone 22210) |
|
9 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|
Anti-Human TNF RII/TNFRSF1B MAb (Clone 22210) |
|
9 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|
Anti-Human TNF RII/TNFRSF1B MAb (Clone 22210) |
|
9 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
[在庫・価格 :2026年04月06日 20時55分現在]
Anti-Human TNF RII/TNFRSF1B MAb (Clone 22210)
文献数: 9
- 商品コード:MAB726-100
- メーカー:RSD
- 包装:100μg
- 価格:¥79,000
- 在庫:無(未発注)
- 納期:10日程度 ※※ 表示されている納期は弊社に在庫がなく、取り寄せた場合の目安納期となります。
- 法規制等:
| 説明文 | 別名:CD120b クローン:22210 Genbank No: 7133 Protein Accession No: P20333 |
||||||
|---|---|---|---|---|---|---|---|
| 別包装品 | 別包装品あり | ||||||
| 法規制等 | |||||||
| 保存条件 | -20℃ | 法規備考 | |||||
| 抗原種 | 免疫動物 | Mouse | |||||
| 交差性 | Human | 適用 | ELISA,Neutralising,Western Blot | ||||
| 標識 | Unlabeled | 性状 | Protein A/G Affinity Purified | ||||
| 吸収処理 | クラス | IgG | |||||
| クロナリティ | Monoclonal | フォーマット | |||||
| 掲載カタログ |
|
||||||
| 製品記事 | |||||||
| 関連記事 | R&D Systems(R&Dシステムズ)社 ELISA用ペア抗体を使用したELISA 構築ガイド |
||||||
Anti-Human TNF RII/TNFRSF1B MAb (Clone 22210)
文献数: 9
- 商品コード:MAB726-500
- メーカー:RSD
- 包装:500μg
- 価格:¥266,000
- 在庫:無(未発注)
- 納期:10日程度 ※※ 表示されている納期は弊社に在庫がなく、取り寄せた場合の目安納期となります。
- 法規制等:
| 説明文 | マッチドペア:Human TNF RII/TNFRSF1B サンドイッチELISAの補足用抗体として利用可能,検出用抗体として#BAF726,スタンダードとして#1089-R2-025を用いる。 別名:CD120b クローン:22210 Genbank No: 7133 Protein Accession No: P20333 |
||||||
|---|---|---|---|---|---|---|---|
| 別包装品 | 別包装品あり | ||||||
| 法規制等 | |||||||
| 保存条件 | -20℃ | 法規備考 | |||||
| 抗原種 | 免疫動物 | Mouse | |||||
| 交差性 | Human | 適用 | ELISA,Neutralising,Western Blot | ||||
| 標識 | Unlabeled | 性状 | Protein A/G Affinity Purified | ||||
| 吸収処理 | クラス | IgG | |||||
| クロナリティ | Monoclonal | フォーマット | |||||
| 掲載カタログ |
|
||||||
| 製品記事 | |||||||
| 関連記事 | R&D Systems(R&Dシステムズ)社 ELISA用ペア抗体を使用したELISA 構築ガイド |
||||||
Anti-Human TNF RII/TNFRSF1B MAb (Clone 22210)
文献数: 9
- 商品コード:MAB726-SP
- メーカー:RSD
- 包装:25μg
- 価格:¥28,000
- 在庫:1個
- 納期:2~3週間 ※※ 表示されている納期は弊社に在庫がなく、取り寄せた場合の目安納期となります。
- 法規制等:
| 説明文 | ※受注発注品。形状:溶液または凍結乾燥 別名:CD120b クローン:22210 Genbank No: 7133 Protein Accession No: P20333 |
||||||
|---|---|---|---|---|---|---|---|
| 別包装品 | 別包装品あり | ||||||
| 法規制等 | |||||||
| 保存条件 | -20℃ | 法規備考 | |||||
| 抗原種 | 免疫動物 | Mouse | |||||
| 交差性 | Human | 適用 | ELISA,Neutralising,Western Blot | ||||
| 標識 | Unlabeled | 性状 | Protein A/G Affinity Purified | ||||
| 吸収処理 | クラス | IgG | |||||
| クロナリティ | Monoclonal | フォーマット | |||||
| 掲載カタログ |
|
||||||
| 製品記事 | 使いっきり抗体 |
||||||
| 関連記事 | R&D Systems(R&Dシステムズ)社 ELISA用ペア抗体を使用したELISA 構築ガイド |
||||||
追加しました。
Product Details
| Species Reactivity | Human |
|---|---|
| Label | Unconjugated |
| Immunogen | E. coli-derived recombinant human TNF RII/TNFRSF1BLeu23-Asp257Accession # P20333 |
| Source | Monoclonal Mouse IgG1 Clone # 22210 |
| Purification | Protein A or G purified from hybridoma culture supernatant |
| Specificity | Detects human TNF RII in ELISAs and Western blots. In ELISAs, no cross-reactivity or interference was observed with recombinant human (rh) TNF RI, recombinant mouse (rm) TNF RI, rmTNF RII, rmTNF‑ alpha, rhTNF‑ alpha, or rhTNF‑ beta. In Western blots, this antibody does notcross‑react with rhTNF RI, rmTNF RI, or rmTNF RII. |
追加しました。
Applications and Data
| Recommended Concentration | Sample | |
| Western Blot | 1 µg/mL | Recombinant Human TNF RII/TNFRSF1B Fc Chimera (Catalog # 726-R2) under non-reducing conditions only |
| Human TNF RII/TNFRSF1B Sandwich Immunoassay | Reagent | |
| ELISA Capture (Matched Antibody Pair) | 2-8 µg/mL | Human TNF RII/TNFRSF1B Antibody (Catalog #MAB726 ) |
| ELISA Detection (Matched Antibody Pair) | 0.1-0.4 µg/mL | Human TNF RII/TNFRSF1B Biotinylated Antibody (Catalog #BAF726 ) |
| ELISA Standard | Recombinant Human TNF RII/TNFRSF1B (aa 24-206) Protein (Catalog #1089-R2 ) | |
| Neutralization | Measured by its ability to neutralize TNF RII/TNFRSF1B-mediated inhibition of cytotoxicity in the L‑929 mouse fibroblast cell line. The Neutralization Dose (ND50) is typically 0.5-1.5 µg/mL in the presence of 0.3 µg/mL Recombinant Human TNF RII/TNFRSF1B Fc Chimera, 0.25 ng/mL Recombinant Human TNF‑ alpha, and 1 µg/mL actinomycin D. | |
| Please Note: Optimal dilutions should be determined by each laboratory for each application.General Protocolsare available in the Technical Information section on our website. | ||
追加しました。
Data Examples
| Neutralization |
![]() click image to view larger | TNF RII/TNFRSF1B Inhibition of TNF‑ alpha -induced Cytotoxicity and Neutralization by Human TNF RII/TNFRSF1B Antibody.Recombinant Human TNF RII/TNFRSF1B Fc Chimera (Catalog # 726-R2) inhibits Recombinant Human TNF‑ alpha (Catalog # 210-TA) induced cytotoxicity in the L‑929 mouse fibroblast cell line in a dose-dependent manner (orange line), as measured by crystal violet staining. Inhibition of Recombinant Human TNF‑ alpha (0.25 ng/mL) activity elicited by Recombinant Human TNF RII/TNFRSF1B Fc Chimera (0.3 µg/mL) is neutralized (green line) by increasing concentrations of Mouse Anti-Human TNF RII/TNFRSF1B Monoclonal Antibody (Catalog # MAB726). The ND50 is typically 0.5-1.5 µg/mL in the presence of the metabolic inhibitor actinomycin D (1 µg/mL). |
| Reconstitution | Reconstitute at 0.5 mg/mL in sterile PBS. | Reconstitution Buffer Available |
| Shipping | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C | |
| Stability & Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. | |
| 1 month, 2 to 8 °C under sterile conditions after reconstitution. | ||
| 6 months, -20 to -70 °C under sterile conditions after reconstitution. | ||
| Background: TNF RII/TNFRSF1B | TNF RII, also known as p75 or p80 TNF R, is a prototypic member of theTNF receptor superfamily and has been designated TNFRSF1B. It binds TNFwith high affinity and is expressed primarily in cells of the immunesystem. | |
| Long Name: | Tumor Necrosis Factor Receptor II | |
| Entrez Gene IDs: | 7133 (Human); 21938 (Mouse); 156767 (Rat) | |
| Alternate Names: | CD120b antigen; CD120b; Etanercept; p75 TNF receptor; p75TBPII; p75TNFR; soluble TNFR1B variant 1; TNF RII; TNFBRp80 TNF-alpha receptor; TNF-R2; TNFR2TNFR1B; TNF-R75; TNFR80; TNFRII; TNF-RII; TNF-R-II; TNFR-II; TNFRSF1B; tumor necrosis factor beta receptor; tumor necrosis factor binding protein 2; Tumor necrosis factor receptor 2; tumor necrosis factor receptor superfamily member 1B; tumor necrosis factor receptor superfamily, member 1B; Tumor necrosis factor receptor type II | |
追加しました。
Related Research Areas
| Adipocytokines | ||||||||
| Cell Structure and Signaling Molecules | ||||||||
| Co-stimulatory and Co-inhibitory Molecules | ||||||||
| Cytokines and Receptors in Allergy and Asthma | ||||||||
| Cytokines and Receptors in Angiogenesis | ||||||||
| Diabetes | ||||||||
| Diabetic Peripheral Neuropathy | ||||||||
| Endothelial Cell Markers | ||||||||
| Neuroinflammation | ||||||||
| Obesity | ||||||||
| Platelet Cytokine and Growth Factor Receptors | ||||||||
| Regulation of Apoptosis by TNF Superfamily Members | ||||||||
| Regulation of Natural Killer Cell Co-stimulation by TNF Superfamily Members | ||||||||
| Regulation of T Cell Co-stimulation by TNF Superfamily Members | ||||||||
| Regulatory T Cells (Tregs) | ||||||||
| T Cell Cytokine Signaling | ||||||||
| TNF Superfamily | ||||||||
| TNF Superfamily Receptors | ||||||||
| ||||||||
| Images | Ratings | Applications | Species | Reviewed By | Date | Details | ||
|---|---|---|---|---|---|---|---|---|
| Excellent | Block/Neutralize | Human | Anonymous | 12/15/2017 | ||||
追加しました。
Summary
| Application | Block/Neutralize | |||||||||
| Sample Tested | Cell culture supernatant | |||||||||
| Species | Human | |||||||||
![]() Enlarge | Excellent | ELISA | Human | Anonymous | 11/22/2017 | Image Details |
![]() ELISA: Human TNF RII/TNFRSF1B Antibody [MAB726]. |
追加しました。
Summary
| Application | ELISA |
| Sample Tested | Cell culture supernatant,Serum and Plasma |
| Species | Human |
| Other Experimental Details | We used MAB726 as the solid phase antibody, 1089-R2 as the immunoassay standard and BAF225 as the detection antibody in a sandwich ELISA. Everything worked very well. |
追加しました。
Related Product & Information
| Long Name | Tumor Necrosis Factor Receptor II |
|---|---|
| Entrez Gene IDs | 7133 (Human); 21938 (Mouse); 156767 (Rat) |
| Background | TNF RII/TNFRSF1B |
| background_content | Background: TNF RII/TNFRSF1B TNF RII, also known as p75 or p80 TNF R, is a prototypic member of the TNF receptor superfamily and has been designated TNFRSF1B. It binds TNF with high affinity and is expressed primarily in cells of the immune system. |
追加しました。
Citations
- Genome-wide comparison between IL-17A- and IL-17F-induced effects in human rheumatoid arthritis synoviocytes.
Authors: Zrioual S, Ecochard R, Tournadre A, Lenief V, Cazalis MA, Miossec P
J. Immunol., 2009;182(0):3112-20.
Species: Human
Sample Type: Whole Cells
Application: Neut - Interaction between transmembrane TNF and TNFR1/2 mediates the activation of monocytes by contact with T cells.
Authors: Rossol M, Meusch U, Pierer M, Kaltenhauser S, Hantzschel H, Hauschildt S, Wagner U
J. Immunol., 2007;179(6):4239-48.
Species: Human
Sample Type: Whole Cells
Application: Neut - Direct comparison of traditional ELISAs and membrane protein arrays for detection and quantification of human cytokines.
Authors: Copeland S, Siddiqui J, Remick D
J. Immunol. Methods, 2004;284(1):99-106.
Species: Human
Sample Type: Cell Culture Supernates
Application: Array Development - A pilot study of pentoxifylline for the treatment of primary sclerosing cholangitis.
Authors: Bharucha AE, Jorgensen R, Lichtman SN, LaRusso NF, Lindor KD
Am. J. Gastroenterol., 2000;95(9):2338-42.
Species: Human
Sample Type: Serum
Application: ELISA Development - Innate immunity associated with inflammatory responses and cytokine production against common dietary proteins in patients with autism spectrum disorder.
Authors: Jyonouchi H, Sun S, Itokazu N
Neuropsychobiology, 0;46(2):76-84.
Species: Human
Sample Type: Whole Cells
Application: ELISA Development
追加しました。
製品情報は掲載時点のものですが、価格表内の価格については随時最新のものに更新されます。お問い合わせいただくタイミングにより製品情報・価格などは変更されている場合があります。
表示価格に、消費税等は含まれていません。一部価格が予告なく変更される場合がありますので、あらかじめご了承下さい。

![Neutralization TNF RII/TNFRSF1B Antibody (22210) [Unconjugated]](https://resources.rndsystems.com/images/datasheets/antibody/TNF_RII_MAB726_Block_Neutralize_2885.jpg)

