抗Human CD4 Phycoerythrin抗体(Anti-Human CD4 Phycoerythrin antibody)

• 価格
• Product Details
• Applications and Data
• Related Product & Information
• Citations

価格

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Product Details

Species Reactivity	Human
Label	Phycoerythrin
Immunogen	Recombinant Human CD4.Extracellular DomainAccession # P01730
Source	Monoclonal Mouse IgG2A Clone # 11830
Purification	Protein A or G purified from hybridoma culture supernatant
Specificity	Detects human CD4 in direct ELISAs.

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Applications and Data

	Recommended Concentration	Sample
Flow Cytometry	10 µL/106 cells	See below

Flow Cytometry

Detection of CD4 in Human Blood Lymphocytes by Flow Cytometry. Human peripheral blood lymphocytes were stained with Mouse Anti-Human CD3 epsilon APC‑conjugated Monoclonal Antibody (Catalog # FAB100A) and either (A) Mouse Anti-Human CD4 PE‑conjugated Monoclonal Antibody (Catalog # FAB3791P) or (B) Mouse IgG2A Phycoerythrin Isotype Control (Catalog # IC003P). View our protocol for Staining Membrane-associated Proteins.

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Related Product & Information

Entrez Gene IDs	920 (Human); 12504 (Mouse); 24932 (Rat); 403931 (Canine); 493775 (Feline)
Background	CD4
background_content	Background: CD4 CD4 is a type I membrane glycoprotein belonging to the immunoglobulin superfamily. It is expressed predominantly on thymocytes and a subset of mature T lymphocytes. CD4 functions in collaboration with the T cell receptor in the recognition of peptide antigens that are presented by class II major histocompatibility complexes. CD4 also has been shown to be a coreceptor of HIV entry and specifically binds gp120, the external envelope glycoprotein of HIV.

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Citations

1. Therapeutic immune monitoring of CD4(+)CD25(+) T cells in chronic myeloid leukemia patients treated with tyrosine kinase inhibitors
   Authors: Z Lu, N Xu, X Zhou, G Gao, L Li, J Huang, Y Li, Q Lu, B He, C Pan, X Liu
   Oncol Lett, 2017;14(2):1363-1372.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


2. Nuclear trafficking of the HIV-1 pre-integration complex depends on the ADAM10 intracellular domain.
   Authors: Endsley M, Somasunderam A, Li G, Oezguen N, Thiviyanathan V, Murray J, Rubin D, Hodge T, O'Brien W, Lewis B, Ferguson M
   Virology, 2014;454(0):60-6.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


3. Long-lasting inhibitory effects of fetal liver mesenchymal stem cells on T-lymphocyte proliferation.
   Authors: Giuliani M, Fleury M, Vernochet A, Ketroussi F, Clay D, Azzarone B, Lataillade JJ, Durrbach A
   2011;6(5):e19988.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


4. Chronically inflamed human tissues are infiltrated by highly differentiated Th17 lymphocytes.
   Authors: Pene J, Chevalier S, Preisser L, Venereau E, Guilleux MH, Ghannam S, Moles JP, Danger Y, Ravon E, Lesaux S, Yssel H, Gascan H
   J. Immunol., 2008;180(0):7423.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


5. Chemokine receptor expression on allergen-specific T cells in asthma and allergic bronchopulmonary aspergillosis.
   Authors: Garcia G, Humbert M, Capel F, Rimaniol AC, Escourrou P, Emilie D, Godot V
   Allergy, 2007;62(2):170-7.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow

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