抗Human CCR5 Fluorescein抗体(Anti-Human CCR5 Fluorescein antibody)

• 価格
• Product Details
• Applications and Data
• Related Product & Information
• Citations

価格

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Product Details

Species Reactivity	Human
Label	Fluorescein
Immunogen	NS0 mouse myeloma cell line transfected with human CCR5Met1-Leu352Accession # P51681
Source	Monoclonal Mouse IgG2B Clone # 45531
Purification	Protein A or G purified from ascites
Specificity	Detects human CCR5.

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Applications and Data

	Recommended Concentration	Sample
Flow Cytometry	10 µL/106 cells	See below

Flow Cytometry
	Detection of CCR5 in NS0 Mouse Cell Line Transfected with Human CCR5 by Flow Cytometry. NS0 mouse myeloma cell line transfected with human CCR5 was stained with Mouse Anti-Human CCR5 Fluorescein‑conjugated Monoclonal Antibody (Catalog # FAB182F, filled histogram) or isotype control antibody (Catalog # IC0041F, open histogram). View our protocol for Staining Membrane-associated Proteins.

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Related Product & Information

Entrez Gene IDs	1234 (Human); 12774 (Mouse); 117029 (Rat); 484789 (Canine); 493769 (Feline)
Background	CCR5
background_content	Background: CCR5 CCR5 is a G protein-linked seven transmembrane domain chemokine receptor. CCR5 serves as a receptor for several chemokines including MIP-1 alpha, MIP-1 beta, MCP-2, and RANTES. It also functions as a coreceptor for macrophage tropic HIV-1 infection.

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Citations

1. Detection of Primary T Cell Responses to Drugs and Chemicals in HLA-Typed Volunteers: Implications for the Prediction of Drug Immunogenicity
   Authors: Lee Faulkner
   Toxicol. Sci, 2016;154(2):416-429.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


2. Involvement of the second extracellular loop and transmembrane residues of CCR5 in inhibitor binding and HIV-1 fusion: insights into the mechanism of allosteric inhibition.
   Authors: Maeda K, Das D, Yin PD, Tsuchiya K, Ogata-Aoki H, Nakata H, Norman RB, Hackney LA, Takaoka Y, Mitsuya H
   J. Mol. Biol., 2008;381(4):956-74.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


3. NF-kappaB modulates sensitivity to apoptosis, proinflammatory and migratory potential in short- versus long-term cultured human gammadelta lymphocytes.
   Authors: Ferrarini M, Delfanti F, Gianolini M, Rizzi C, Alfano M, Lazzarin A, Biswas P
   J. Immunol., 2008;181(9):5857-64.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


4. Inhibition of HIV-1 infection by viral chemokine U83A via high-affinity CCR5 interactions that block human chemokine-induced leukocyte chemotaxis and receptor internalization.
   Authors: Catusse J, Parry CM, Dewin DR, Gompels UA
   Blood, 2007;109(9):3633-9.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow


5. Phenotypic and functional analysis of T cells homing into the CSF of subjects with inflammatory diseases of the CNS.
   Authors: Giunti D, Borsellino G, Benelli R, Marchese M, Capello E, Valle MT, Pedemonte E, Noonan D, Albini A, Bernardi G, Mancardi GL, Battistini L, Uccelli A
   J. Leukoc. Biol., 2003;73(5):584-90.
   Species: Human
   Sample Type: Whole Cells
   Application: Flow

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