抗I-TAC抗体(Anti-I-TAC, Human, Goat-Poly, Biotin antibody)
掲載日情報：2021/01/28 現在Webページ番号：27840
I-TACに対する抗体(Anti-I-TAC, Human, Goat-Poly, Biotin )です。
※ 本製品は研究用です。研究用以外には使用できません。
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- 価格
- Product Details
- Applications and Data
- References
- Related Research Areas
- Related Product & Information
- Citations
価格
[在庫・価格 ：2025年04月26日 20時55分現在]
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Anti-I-TAC, Human, Goat-Poly, Biotin <Anti-CXCL11> |
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[在庫・価格 ：2025年04月26日 20時55分現在]
Anti-I-TAC, Human, Goat-Poly, Biotin <Anti-CXCL11>
文献数： 2
- 商品コード：BAF672
- メーカー：RSD
- 包装：50μg
- 価格：¥118,000
- 在庫：無(未発注)
- 納期：10日程度 ※※ 表示されている納期は弊社に在庫がなく、取り寄せた場合の目安納期となります。
- 法規制等：
| 説明文 | マッチドペア：Human CXCL11/I-TAC サンドイッチELISAの検出用抗体として利用可能，補足用抗体として#MAB672-500，スタンダードとして#672-IT-025を用いる。 別名：beta-R1 Genbank No： 6373 Protein Accession No： O14625 |
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| 法規制等 | |||
| 保存条件 | -20℃ | 法規備考 | |
| 抗原種 | Human | 免疫動物 | Goat |
| 交差性 | Human | 適用 | ELISA,Western Blot |
| 標識 | Biotin | 性状 | Antigen Affinity Purified |
| 吸収処理 | クラス | IgG | |
| クロナリティ | Polyclonal | フォーマット | |
| 掲載カタログ |
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| 製品記事 | M1/M2 Macrophage Activation Marker |
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| 関連記事 | R&D Systems(R&Dシステムズ)社 ELISA用ペア抗体を使用したELISA 構築ガイド |
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Product Details
| Species Reactivity | Human |
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| Label | Biotin |
| Immunogen | E. coli-derived recombinant human CXCL11/I-TAC (R&D Systems, Catalog # 672-IT)Phe22-Phe94Accession # O14625 |
| Source | Polyclonal Goat IgG |
| Purification | Antigen Affinity-purified |
| Specificity | Detects human I-TAC in ELISAs and Western blots. In sandwich immunoassays, less than 0.05% cross‑reactivity with rhENA-78, rhIL-8, rhIP-10, rhMIG and rhNAP‑2 is observed. |
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Applications and Data
| Recommended Concentration | Sample | |
| Western Blot | 0.1 µg/mL | Recombinant Human CXCL11/I-TAC (Catalog # 672-IT) |
| Human CXCL11/I-TAC Sandwich Immunoassay | Reagent | |
| ELISA Capture (Matched Antibody Pair) | 2-8 µg/mL | Human CXCL11/I‑TAC Antibody (Catalog #MAB672 ) |
| ELISA Detection (Matched Antibody Pair) | 0.1-0.4 µg/mL | Human CXCL11/I-TAC Biotinylated Antibody (Catalog #BAF672 ) |
| ELISA Standard | Recombinant Human CXCL11/I-TAC Protein (Catalog #672-IT ) | |
| Please Note: Optimal dilutions should be determined by each laboratory for each application.General Protocolsare available in the Technical Information section on our website. | Preparation and Storage | |
| Reconstitution | Reconstitute at 0.2 mg/mL in sterile PBS. | Reconstitution Buffer Available |
| Shipping | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. | |
| Stability & Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. | |
| 1 month, 2 to 8 °C under sterile conditions after reconstitution. | ||
| 6 months, -20 to -70 °C under sterile conditions after reconstitution. | ||
| Background: CXCL11/I-TAC | CXCL11, also known as I-TAC, SCYB9B, H174 and beta -R1, is a non-ELR CXC chemokine. CXCL11 cDNA encodes a 94 amino acid (aa) residue precursor protein with a 21 aa residue putative signal sequence, which is cleaved to form the mature 73 aa residue protein. CXCL11 shares 36% and 37% amino acid sequence homology with IP-10 and MIG (two other known human non-ELR CXC chemokines), respectively. CXCL11 is expressed at low levels in normal tissues including thymus, spleen and pancreas. The expression of CXCL11 mRNA is radically up regulated in IFN-gamma and IL-1 stimulated astrocytes. Moderate increase in expression is also observed in stimulated monocytes. CXCL11 has potent chemoattractant activity for IL-2 activated T cells and transfected cell lines expressing CXCR3 but not freshly isolated T cells, neutrophils or monocytes. The gene encoding CXCL11 has been mapped to chromosome 4. |
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References
| Cole, K. et al. (1998) J. Exp. Med. 187:2009. | |
| Sandhya Rani, M. et al. (1996) J. Biol. Chem. 271:22878. | |
| Lou, Y. et al. (1998) J. Neurovirol. 4:575. | |
| Entrez Gene IDs: | 6373 (Human); 56066 (Mouse) |
| Alternate Names: | beta-R1; b-R1; chemokine (C-X-C motif) ligand 11; CXCL11; H174; H174IP9; Interferon gamma-inducible protein 9; Interferon-inducible T-cell alpha chemoattractant; IP-9member 11; ITAC; I-TAC; I-TACMGC102770; SCYB9B; small inducible cytokine subfamily B (Cys-X-Cys), member 9B; Small-inducible cytokine B11 |
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Related Research Areas
| Chemokines and Receptors | ||
| Chemokines and Receptors in Angiogenesis | ||
| CXC Chemokines and Receptors | ||
| Macrophage Activation Markers | ||
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Related Product & Information
| Background | CXCL11/I-TAC |
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| background_content | Background: CXCL11/I-TAC CXCL11, also known as I-TAC, SCYB9B, H174 and beta -R1, is a non-ELR CXC chemokine. CXCL11 cDNA encodes a 94 amino acid (aa) residue precursor protein with a 21 aa residue putative signal sequence, which is cleaved to form the mature 73 aa residue protein. CXCL11 shares 36% and 37% amino acid sequence homology with IP-10 and MIG (two other known human non-ELR CXC chemokines), respectively. CXCL11 is expressed at low levels in normal tissues including thymus, spleen and pancreas. The expression of CXCL11 mRNA is radically up regulated in IFN-gamma and IL-1 stimulated astrocytes. Moderate increase in expression is also observed in stimulated monocytes. CXCL11 has potent chemoattractant activity for IL-2 activated T cells and transfected cell lines expressing CXCR3 but not freshly isolated T cells, neutrophils or monocytes. The gene encoding CXCL11 has been mapped to chromosome 4. |
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Citations
- Characterization of the chemokine CXCL11-heparin interaction suggests two different affinities for glycosaminoglycans.
Authors: Severin IC, Gaudry JP, Johnson Z, Kungl A, Jansma A, Gesslbauer B, Mulloy B, Power C, Proudfoot AE, Handel T
J. Biol. Chem., 2010;285(23):17713-24.
Species: Human
Sample Type: Protein
Application: ELISA Development - Enhanced generation of helper T type 1 and 2 chemokines in allergen-induced asthma.
Authors: Liu L, Jarjour NN, Busse WW, Kelly EA
Am. J. Respir. Crit. Care Med., 2004;169(10):1118-24.
Species: Human
Sample Type: BALF
Application: ELISA Development
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